生物化学与生物物理进展最新文献

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New Progress of Glycan as Receptors for Influenza Virus*: New Progress of Glycan as Receptors for Influenza Virus* 聚糖作为流感病毒受体的新进展*:聚糖作为流感病毒受体的新进展*
IF 0.3 4区 生物学
生物化学与生物物理进展 Pub Date : 2012-08-06 DOI: 10.3724/SP.J.1206.2011.00618
Y. Zhong, Yannan Qin, Shisheng Sun, Wentian Chen, Zheng Li
{"title":"New Progress of Glycan as Receptors for Influenza Virus*: New Progress of Glycan as Receptors for Influenza Virus*","authors":"Y. Zhong, Yannan Qin, Shisheng Sun, Wentian Chen, Zheng Li","doi":"10.3724/SP.J.1206.2011.00618","DOIUrl":"https://doi.org/10.3724/SP.J.1206.2011.00618","url":null,"abstract":"","PeriodicalId":20655,"journal":{"name":"生物化学与生物物理进展","volume":"26 1","pages":"605-612"},"PeriodicalIF":0.3,"publicationDate":"2012-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84224931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prospect of Building The Strategic Alliances of Technical Innovation in China Biomedical Industry: Prospect of Building The Strategic Alliances of Technical Innovation in China Biomedical Industry 构建中国生物医药产业技术创新战略联盟的展望——构建中国生物医药产业技术创新战略联盟的展望
IF 0.3 4区 生物学
生物化学与生物物理进展 Pub Date : 2012-08-06 DOI: 10.3724/SP.J.1206.2012.00199
N. Deng, Yi Ao, Zhen-He Guan, Yue Su
{"title":"Prospect of Building The Strategic Alliances of Technical Innovation in China Biomedical Industry: Prospect of Building The Strategic Alliances of Technical Innovation in China Biomedical Industry","authors":"N. Deng, Yi Ao, Zhen-He Guan, Yue Su","doi":"10.3724/SP.J.1206.2012.00199","DOIUrl":"https://doi.org/10.3724/SP.J.1206.2012.00199","url":null,"abstract":"","PeriodicalId":20655,"journal":{"name":"生物化学与生物物理进展","volume":"161 1","pages":"631-639"},"PeriodicalIF":0.3,"publicationDate":"2012-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77369408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Association of Single Nucleotide Polymorphisms of NBS1 Gene With Genetic Susceptibility to Primary Liver Cancer in a Chinese Han Population*: Association of Single Nucleotide Polymorphisms of NBS1 Gene With Genetic Susceptibility to Primary Liver Cancer in a Chinese Han Population* 中国汉族人群NBS1基因单核苷酸多态性与原发性肝癌遗传易感性的关联*:中国汉族人群NBS1基因单核苷酸多态性与原发性肝癌遗传易感性的关联*
IF 0.3 4区 生物学
生物化学与生物物理进展 Pub Date : 2012-08-06 DOI: 10.3724/SP.J.1206.2011.00536
Jian Huang, Yan-ping Zhao, Qian Li, Junxian Zhang, Y. Wang, Bei Zhang
{"title":"Association of Single Nucleotide Polymorphisms of NBS1 Gene With Genetic Susceptibility to Primary Liver Cancer in a Chinese Han Population*: Association of Single Nucleotide Polymorphisms of NBS1 Gene With Genetic Susceptibility to Primary Liver Cancer in a Chinese Han Population*","authors":"Jian Huang, Yan-ping Zhao, Qian Li, Junxian Zhang, Y. Wang, Bei Zhang","doi":"10.3724/SP.J.1206.2011.00536","DOIUrl":"https://doi.org/10.3724/SP.J.1206.2011.00536","url":null,"abstract":"","PeriodicalId":20655,"journal":{"name":"生物化学与生物物理进展","volume":"52 1","pages":"678-686"},"PeriodicalIF":0.3,"publicationDate":"2012-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76899699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Impaired Post-transcriptional Regulation in Alzheimer′s Disease 阿尔茨海默病的转录后调控受损
IF 0.3 4区 生物学
生物化学与生物物理进展 Pub Date : 2012-08-01 DOI: 10.3724/SP.J.1206.2012.00211
Zhu Li, 朱笠, Liu Jianghong, Wu Ying
{"title":"Impaired Post-transcriptional Regulation in Alzheimer′s Disease","authors":"Zhu Li, 朱笠, Liu Jianghong, Wu Ying","doi":"10.3724/SP.J.1206.2012.00211","DOIUrl":"https://doi.org/10.3724/SP.J.1206.2012.00211","url":null,"abstract":"Post-transcriptional regulation plays a central role in the development and maintenance of the nervous system.Defects in post-transcriptional regulation lead to neurodegenerative diseases.Mounting evidence suggests that the impaired post-transcriptional regulation of associated genes contribute to the neurodegenerative process,such as Alzheimer's disease(AD).This review discusses the role of disruption of alternative splicing regulation of the human tau gene(MAPT) and alterations of microRNA expression in the pathogenesis of neurodegeneration including AD.A brief overview is provided for the role and the mechanism of post-transcriptional regulation in AD pathogenesis.","PeriodicalId":20655,"journal":{"name":"生物化学与生物物理进展","volume":"105 1","pages":"703-708"},"PeriodicalIF":0.3,"publicationDate":"2012-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79411362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Novel Characters of Myxobacterial Modular Natural Product Assembly Lines*: Novel Characters of Myxobacterial Modular Natural Product Assembly Lines* 黏菌模块化天然产品装配线的新特性*:黏菌模块化天然产品装配线的新特性*
IF 0.3 4区 生物学
生物化学与生物物理进展 Pub Date : 2012-07-30 DOI: 10.3724/SP.J.1206.2011.00325
Li-Ping Zhu, Zhi-feng Li, Kui Han, Shu-guang Li, Yue-zhong Li
{"title":"Novel Characters of Myxobacterial Modular Natural Product Assembly Lines*: Novel Characters of Myxobacterial Modular Natural Product Assembly Lines*","authors":"Li-Ping Zhu, Zhi-feng Li, Kui Han, Shu-guang Li, Yue-zhong Li","doi":"10.3724/SP.J.1206.2011.00325","DOIUrl":"https://doi.org/10.3724/SP.J.1206.2011.00325","url":null,"abstract":"","PeriodicalId":20655,"journal":{"name":"生物化学与生物物理进展","volume":"6 1","pages":"525-539"},"PeriodicalIF":0.3,"publicationDate":"2012-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72720556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Progress on Whole Brain Imaging Methods at The Level of Optical Microscopy*: Progress on Whole Brain Imaging Methods at The Level of Optical Microscopy* 光学显微镜水平全脑成像方法的进展*:光学显微镜水平全脑成像方法的进展*
IF 0.3 4区 生物学
生物化学与生物物理进展 Pub Date : 2012-07-30 DOI: 10.3724/SP.J.1206.2012.00237
A. Li, H. Gong
{"title":"Progress on Whole Brain Imaging Methods at The Level of Optical Microscopy*: Progress on Whole Brain Imaging Methods at The Level of Optical Microscopy*","authors":"A. Li, H. Gong","doi":"10.3724/SP.J.1206.2012.00237","DOIUrl":"https://doi.org/10.3724/SP.J.1206.2012.00237","url":null,"abstract":"","PeriodicalId":20655,"journal":{"name":"生物化学与生物物理进展","volume":"40 1","pages":"498-504"},"PeriodicalIF":0.3,"publicationDate":"2012-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78451731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Sirtuin 1 Maitains Survival via PKB Signaling in Degenerative Human Disc Nucleus Pulposus Cells*: Sirtuin 1 Maitains Survival via PKB Signaling in Degenerative Human Disc Nucleus Pulposus Cells* Sirtuin 1通过PKB信号传导维持退行性人椎间盘髓核细胞的存活*:Sirtuin 1通过PKB信号传导维持退行性人椎间盘髓核细胞的存活*
IF 0.3 4区 生物学
生物化学与生物物理进展 Pub Date : 2012-07-30 DOI: 10.3724/SP.J.1206.2011.00484
Dawu Wang, Zhenming Hu, J. Hao, Bin He, Qiang Gan, Xiao-ming Zhong, Jieliang Shen, Ji Fang
{"title":"Sirtuin 1 Maitains Survival via PKB Signaling in Degenerative Human Disc Nucleus Pulposus Cells*: Sirtuin 1 Maitains Survival via PKB Signaling in Degenerative Human Disc Nucleus Pulposus Cells*","authors":"Dawu Wang, Zhenming Hu, J. Hao, Bin He, Qiang Gan, Xiao-ming Zhong, Jieliang Shen, Ji Fang","doi":"10.3724/SP.J.1206.2011.00484","DOIUrl":"https://doi.org/10.3724/SP.J.1206.2011.00484","url":null,"abstract":"","PeriodicalId":20655,"journal":{"name":"生物化学与生物物理进展","volume":"86 1","pages":"563-573"},"PeriodicalIF":0.3,"publicationDate":"2012-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88515826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
UNC-10 Regulates The Docking Step of DCV Exocytosis in C. elegans UNC-10调控秀丽隐杆线虫DCV胞吐的对接步骤
IF 0.3 4区 生物学
生物化学与生物物理进展 Pub Date : 2012-07-30 DOI: 10.3724/SP.J.1206.2011.00374
Feng WanJuan, Zhou Wei, Zhang Yongdeng, Wu Zheng-xing, Xu Tao, 徐涛
{"title":"UNC-10 Regulates The Docking Step of DCV Exocytosis in C. elegans","authors":"Feng WanJuan, Zhou Wei, Zhang Yongdeng, Wu Zheng-xing, Xu Tao, 徐涛","doi":"10.3724/SP.J.1206.2011.00374","DOIUrl":"https://doi.org/10.3724/SP.J.1206.2011.00374","url":null,"abstract":"","PeriodicalId":20655,"journal":{"name":"生物化学与生物物理进展","volume":"24 1","pages":"556-562"},"PeriodicalIF":0.3,"publicationDate":"2012-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82782823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
sTn is a Novel Biomarker for Type I Endometrial Carcinoma sTn是I型子宫内膜癌的一种新的生物标志物
IF 0.3 4区 生物学
生物化学与生物物理进展 Pub Date : 2012-07-30 DOI: 10.3724/SP.J.1206.2012.00185
An Yunhe, Zhang Haofeng, S. Min, Z. Jun, Chen Xiuqin, Chen Dong, L. Di, F. Jing, Yang Dongling, S. Lina, Y. Xiyun, 阎锡蕴, J. Zhang
{"title":"sTn is a Novel Biomarker for Type I Endometrial Carcinoma","authors":"An Yunhe, Zhang Haofeng, S. Min, Z. Jun, Chen Xiuqin, Chen Dong, L. Di, F. Jing, Yang Dongling, S. Lina, Y. Xiyun, 阎锡蕴, J. Zhang","doi":"10.3724/SP.J.1206.2012.00185","DOIUrl":"https://doi.org/10.3724/SP.J.1206.2012.00185","url":null,"abstract":"Sialyl-Tn(sTn) is a tumor-associated carbohydrate antigen overexpressed in many carcinomas.But whether it is expressed in neoplastic human endometrium is controversial.Here we screened 111 clinical samples including 82 endometrial cancers,16 atypical hyperplastic and 13 normal endometria,by immunohistochemistry using a novel anti-sTn antibody,namely 3P9.Our results showed that the expression of sTn in the endometrial carcinoma was significantly higher(76%) than that in normal tissues(31%)(P 0.01) and in atypical hyperplasia(44%)(P 0.05).Importantly,we found that sTn expression in typeⅠ carcinoma(80%) was obviously higher than that in typeⅡ(45%)(P 0.05).These results suggested that sTn may be a biomarker for endometrial carcinoma,especially for typeⅠcarcinoma.Moreover,we observed that sTn expression was increased with the decline of tumor histological grade(P 0.05),indicating that sTn was associated with a favorable prognosis in endometrial carcinoma.","PeriodicalId":20655,"journal":{"name":"生物化学与生物物理进展","volume":"40 1","pages":"548-555"},"PeriodicalIF":0.3,"publicationDate":"2012-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87431486","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
A Novel Scale-free Network Construction Method and Its Application in Gene Expression Profiles Simulation*: A Novel Scale-free Network Construction Method and Its Application in Gene Expression Profiles Simulation* 一种新的无标度网络构建方法及其在基因表达谱模拟中的应用*:一种新的无标度网络构建方法及其在基因表达谱模拟中的应用*
IF 0.3 4区 生物学
生物化学与生物物理进展 Pub Date : 2012-07-30 DOI: 10.3724/SP.J.1206.2011.00311
Ming Zheng, Yanxin Huang, Wei-Lun Shen, Yi Zhong, Jianan Wu, Guixia Liu, You Zhou
{"title":"A Novel Scale-free Network Construction Method and Its Application in Gene Expression Profiles Simulation*: A Novel Scale-free Network Construction Method and Its Application in Gene Expression Profiles Simulation*","authors":"Ming Zheng, Yanxin Huang, Wei-Lun Shen, Yi Zhong, Jianan Wu, Guixia Liu, You Zhou","doi":"10.3724/SP.J.1206.2011.00311","DOIUrl":"https://doi.org/10.3724/SP.J.1206.2011.00311","url":null,"abstract":"","PeriodicalId":20655,"journal":{"name":"生物化学与生物物理进展","volume":"14 1","pages":"581-590"},"PeriodicalIF":0.3,"publicationDate":"2012-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77725629","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
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