Progress in Nutrition最新文献_第6页

Effect of Nigella sativa oil extract on inflammatory cytokine response and oxidative stress among people with type 2 diabetes mellitus: a randomized, double-blind, placebo controlled trial 黑草油提取物对2型糖尿病患者炎症细胞因子反应和氧化应激的影响:一项随机、双盲、安慰剂对照试验

4区医学

Progress in Nutrition Pub Date : 2018-08-06 DOI: 10.23751/PN.V20I1-S.6062

Saeid Hadi, P. Mirmiran, Reza Daryabeygi-Khotbesara, Vahid Hadi

{"title":"Effect of Nigella sativa oil extract on inflammatory cytokine response and oxidative stress among people with type 2 diabetes mellitus: a randomized, double-blind, placebo controlled trial","authors":"Saeid Hadi, P. Mirmiran, Reza Daryabeygi-Khotbesara, Vahid Hadi","doi":"10.23751/PN.V20I1-S.6062","DOIUrl":"https://doi.org/10.23751/PN.V20I1-S.6062","url":null,"abstract":"Objectives: Diabetes mellitus (DM) is the most common chronic disease and a challenging global health problem. Inflammation plays a key role in the pathogenesis of DM. The experimental studies have shown that Nigella sativa (N. sativa) oil extract is a potential anti-inflammatory and anti-oxidant substance. The present study was conducted to evaluate the anti-inflammatory and antioxidant effects of N. sativa among adults diagnosed with type 2 diabetes (T2D). Methods: A double-blind placebo controlled trial was designed. A total of 43 participants were assigned into either intervention (N=23) or control (N=20) conditions. The intervention group received 500 mg N. sativa capsules twice a day, while control group received identical amounts of placebo capsules twice a day for 8 weeks. Dietary intake, physical activity, anthropometric indices, and fasting blood samples were measured at baseline and one week post-intervention. Results: Findings revealed significant reductions in malondialdehyde (MDA) and nitric oxide (NO) within the intervention condition, although between-group analysis did not show any significant changes neither for MAD nor NO. Besides, within- and between-group analyses did not show any significant differences pre- and post-intervention for interleukin 1β (IL-1β), tumor necrosis factor-α (TNF-α), superoxide dismutase (SOD), and catalase (CAT). Conclusions: The current study revealed favorable effects for N. sativa oil extract in reducing MDA and NO among people with T2D. However, future research is needed to establish potential anti-inflammatory and anti-oxidative responses of N. sativa in diabetes.","PeriodicalId":20600,"journal":{"name":"Progress in Nutrition","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42998919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 23

Effects of coconut oil (Cocos nucifera) and sesame oils (Sesamum indicum L.) on rapeseed powder induced changes of cardio-hepatic enzymes in Wistar rats. 椰子油和芝麻油对菜籽粉诱导Wistar大鼠肝心酶变化的影响。

4区医学

Progress in Nutrition Pub Date : 2018-08-06 DOI: 10.23751/PN.V20I1-S.5543

H. Rahman, Shaikh Shahinur Rahman

引用次数: 0

Canola oil and olive oil impact on lipid profile and blood pressure in women with type 2 diabetes: a randomized, controlled trial 菜籽油和橄榄油对2型糖尿病女性血脂和血压的影响:一项随机对照试验

4区医学

Progress in Nutrition Pub Date : 2018-08-06 DOI: 10.23751/PN.V20I1-S.5854

Masoumeh Atefi, G. Pishdad, S. Faghih

{"title":"Canola oil and olive oil impact on lipid profile and blood pressure in women with type 2 diabetes: a randomized, controlled trial","authors":"Masoumeh Atefi, G. Pishdad, S. Faghih","doi":"10.23751/PN.V20I1-S.5854","DOIUrl":"https://doi.org/10.23751/PN.V20I1-S.5854","url":null,"abstract":"Objective: A number of studies indicated that olive oil (OO) and canola oil (CO) have lipid-lowering and blood pressure-lowering effects. This clinical trial was done to compare the effects of CO and OO on serum lipids and blood pressure in women with type 2 diabetes. Methods: This randomized controlled clinical trial was done on 77 type 2 diabetic women. 4 weeks before the intervention, lipid-lowering drugs intakes were cut under the supervision of an endocrinologist. The participants were randomly allocated into 2 intervention groups (Balanced diet + 30 grams/day OO or CO) and one control group (Balanced diet + 30 grams/day of sunflower oil (SFO)). Dietary intakes were assessed using three 24-hour food records at baseline and at weeks 4 and 8 of the interventions. At baseline and after 8 weeks, height, weight, waist circumference, systolic blood pressure (SBP), diastolic blood pressure (DBP), serum total cholesterol (TC), triglycerides (TG), low-density lipoprotein cholesterol (LDL-C), very low-density lipoprotein (VLDL-C) and high-density lipoprotein cholesterol (HDL-C) were measured and the data were statistically analyzed by SPSS 19. Results: After treatment, SBP (p=0.02), TG (p=0.01) and VLDL-C (p=0.02) were significantly decreased in OO group. None of the variables had significant changes in CO or SFO groups. There were no significant differences in the blood pressure and lipid profile among 3 groups. Conclusion: Although we found no differences between the effects of CO, OO, and SFO, it seems that replacing CO and SFO by OO may have some beneficial effects on SBP, TG and VLDL-C in women with type 2 diabetes.","PeriodicalId":20600,"journal":{"name":"Progress in Nutrition","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46919976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 15

In vitro propagation of Cataloglu Apricot (Prunus armeniaca L.) cultivar using apical node as explant 以杏心尖节为外植体的杏品种离体繁殖

4区医学

Progress in Nutrition Pub Date : 2018-08-06 DOI: 10.23751/PN.V20I1-S.5576

F. A. Özdemir, N. Gur

引用次数: 4

Influence of gamma irradiation on microflora, sensory quality, nutritional properties and shelf life of Desi chickpea (Cicer arietinum) γ辐照对鹰嘴豆微生物区系、感官品质、营养特性和保质期的影响

4区医学

Progress in Nutrition Pub Date : 2018-08-06 DOI: 10.23751/PN.V20I1-S.5961

R. Abdullah, M. Zulfiqar, Z. Akram, M. Iqtedar, A. Kaleem, S. Naz

引用次数: 1

Sensory attributes of mineral fortified low fat buffalo milk Cheddar cheese 矿物质强化低脂水牛奶切达奶酪的感官特性

4区医学

Progress in Nutrition Pub Date : 2018-08-06 DOI: 10.23751/PN.V20I1-S.5415

R. Perveen, Masood Sadiq, H. A. Sakandar

{"title":"Sensory attributes of mineral fortified low fat buffalo milk Cheddar cheese","authors":"R. Perveen, Masood Sadiq, H. A. Sakandar","doi":"10.23751/PN.V20I1-S.5415","DOIUrl":"https://doi.org/10.23751/PN.V20I1-S.5415","url":null,"abstract":"Buffalo milk was fortified with different sources of calcium (Ca) and phosphorous (P) to manufacture of cheddar cheese. It was fortified with calcium chloride (CaCl2) and trisodium phosphate (Na3PO4) at level of 10 (T1), 20 (T2) and 30 (T3) mM/ milk. All samples of cheddar cheese (0, 15 and 30 days) were analyzed for moisture, fat, mineral profile such as calcium, sodium, phosphorous and potassium, sensory analysis (hand firmness, chew down degree of breakdown and chew down smoothness). The fat content of Ca and P enriched cheeses exhibited significant differences due to treatments (23.87±0.63to 23.13±0.56%). No obvious significantly effects were observed in moisture fat, mineral profile, ash and organoleptic characteristics on cheddar cheeses during ripening. The salt fortified cheese showed significant effect of mineral with treatments; sodium (612.52±4.17 to 634.47±7.68 mg/100g), potassium (64.76±2.21 to 74.04±2.02mg/100g), calcium (831.58±4.55 to 874.45±2.62mg/100g). Additionally, hedonic response of developed cheeses was significantly affected due to treatments. Decisively, colloidal supramolecular structures of caseins in buffalo milk play a pivotal role in cheese making and other related organoleptic characteristics. Thus, buffalo milk casein along with calcium and phosphorus incorporation for the development of novel cheese formulation is a pragmatic approach in the field of dairy technology.","PeriodicalId":20600,"journal":{"name":"Progress in Nutrition","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45948546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of saffron on serum leptin levels in patients with metabolic syndrome, a double-blind, randomized and placebo-controlled trial study 藏红花对代谢综合征患者血清瘦素水平的影响，一项双盲、随机和安慰剂对照的试验研究

4区医学

Progress in Nutrition Pub Date : 2018-08-06 DOI: 10.23751/PN.V20I1-S.6078

M. Zilaee, M. Soukhtanloo, M. Ghayour-Mobarhan, Maryam Shemshian, M. Salehi, G. Ferns

{"title":"Effect of saffron on serum leptin levels in patients with metabolic syndrome, a double-blind, randomized and placebo-controlled trial study","authors":"M. Zilaee, M. Soukhtanloo, M. Ghayour-Mobarhan, Maryam Shemshian, M. Salehi, G. Ferns","doi":"10.23751/PN.V20I1-S.6078","DOIUrl":"https://doi.org/10.23751/PN.V20I1-S.6078","url":null,"abstract":"Background: Metabolic syndrome is a risk factor for cardiovascular disease and diabetes mellitus. A decreased level of serum leptin is reported for obese populations. Beneficial effects of saffron on human health, including appetite-regulation, have been reported previously. The aim of this study was to investigating the effect of saffron supplementation on serum leptin levels in patients with metabolic syndrome. Material and method: Patients with metabolic syndrome were randomly divided into two groups; a case group, receiving saffron and a control group, receiving placebo. Concentration of serum leptin was measured at baseline and after 12 weeks of the start of study. SPSS software was used to analyze the data. Results: There was a borderline (p=0.05) significant difference in serum leptin before and after treatment with saffron, but not in the placebo group. There was a significant difference in serum leptin concentrations between the groups (p=0.001). Conclusion: Saffron supplementation has no significant effect on serum leptin levels in patients with metabolic syndrome.","PeriodicalId":20600,"journal":{"name":"Progress in Nutrition","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46176606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 10

The effect of chamomile (Matricaria recutita L.) infusion on blood glucose, lipid profile and kidney function in type 2 diabetic patients: a randomized clinical trial 洋甘菊输注对2型糖尿病患者血糖、血脂及肾功能的影响:一项随机临床试验

4区医学

Progress in Nutrition Pub Date : 2018-08-06 DOI: 10.23751/PN.V20I1-S.5884

F. Kaseb, Zeinab Yazdanpanah, Akram Naghdipour Biregani, Nahid Yazdi, Z. Yazdanpanah

{"title":"The effect of chamomile (Matricaria recutita L.) infusion on blood glucose, lipid profile and kidney function in type 2 diabetic patients: a randomized clinical trial","authors":"F. Kaseb, Zeinab Yazdanpanah, Akram Naghdipour Biregani, Nahid Yazdi, Z. Yazdanpanah","doi":"10.23751/PN.V20I1-S.5884","DOIUrl":"https://doi.org/10.23751/PN.V20I1-S.5884","url":null,"abstract":"Introduction: Chamomile is one of the medicinal herbs, frequently used in traditional medicine for treatment of diabetes. Therefore this study aimed to evaluate the effects of chamomile herbal tea on glycemic index, lipid profile and kidney function in type 2 diabetic patients. Methods: This randomized clinical trial was conducted on 50 diabetic patients. The intervention group received standard treatment with orally 200 ml/day of chamomile infusion (10 g/100 mL boiling water) twice a day before meals (lunch and dinner) for 4 weeks. The control group only received standard therapy. Results: Consumption of the chamomile infusion was accompanied by a significant reduction in total cholesterol (TC) (p= 0.02), low density lipoprotein cholesterol (LDL-C) (p= 0.04) and creatinine (Cr) (p= 0.03). Within-group comparisons showed there was a significant decrease in fasting blood sugar and 2-h postprandial glucose in the intervention group (p= 0.01), (p= 0.03), respectively. Conclusions: Chamomile has potential desirable effects on serum levels of TC, LDL-C and Cr in patients with type 2 diabetes taking oral hypoglycemic agent.","PeriodicalId":20600,"journal":{"name":"Progress in Nutrition","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47015996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 15

Grifola Frondosa Polysaccharide (GFP) improves neutrophils immune function of heavy load exercising rats 灰树花多糖改善大鼠中性粒细胞免疫功能

4区医学

Progress in Nutrition Pub Date : 2018-08-02 DOI: 10.23751/PN.V20I1-S.5507

Jian-ting Huang, Yali Shi, Minjun Sun

{"title":"Grifola Frondosa Polysaccharide (GFP) improves neutrophils immune function of heavy load exercising rats","authors":"Jian-ting Huang, Yali Shi, Minjun Sun","doi":"10.23751/PN.V20I1-S.5507","DOIUrl":"https://doi.org/10.23751/PN.V20I1-S.5507","url":null,"abstract":"Grifola frondosa polysaccharide (GFP) is the extract of Grifola frondosa. In this study, 50 male wistar rats were separated into S + C, S + T, LG + T, MG + T and HG + T groups to study the effect of GFP on the immune function of heavy load exercising rats. In S + T group, blood neutrophil number, neutrophil phagocytic index and bactericidal capacity decreased significantly, and adhesion function showed remarkable increase after 8 weeks excessive exercise. Low, medium and high doses of GFP were administered to different groups based on gavage. After gavaging GFP during the eight weeks of excessive exercise, blood neutrophils in the MG + T group and HG + T group were 15.3% and 7.9% higher than in the S + T group. The blood neutrophil phagocytic indices in the MG + T and HG + T groups increased to 1.19 and 1.20, respectively, from 1.02 in the S + T group. The neutrophil bactericidal ability of blood cells in the MG + T and HG + T groups was also observed to be 46.6% and 45.6%, respectively, in comparison with 39.7% for S + T and 39.2% for LG + T group. Blood neutrophil adhesion function in the MG + T and HG + T groups was 57.4% and 57.6%, respectively. This is significantly lower than 65.6% in the S+T group. We demonstrate that feeding a medium or high dose of GFP can improve the neutrophil immune function of excessively exercising rats. A medium dose of GFP shows the most significant effect.","PeriodicalId":20600,"journal":{"name":"Progress in Nutrition","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48572559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effects of Cornus walteri extract on hepatic lipid-regulating enzyme activities in high fat diet-induced obese rats 山茱萸提取物对高脂饮食诱导的肥胖大鼠肝脏脂质调节酶活性的影响

4区医学

Progress in Nutrition Pub Date : 2018-08-02 DOI: 10.23751/PN.V20I1-S.5237

S. Yun, JoonHo Lee, H. Suh, E. Jung

{"title":"Effects of Cornus walteri extract on hepatic lipid-regulating enzyme activities in high fat diet-induced obese rats","authors":"S. Yun, JoonHo Lee, H. Suh, E. Jung","doi":"10.23751/PN.V20I1-S.5237","DOIUrl":"https://doi.org/10.23751/PN.V20I1-S.5237","url":null,"abstract":"In this study, we investigated whether the body fat suppressive effects of Cornus walteri extract (CE) were due to alterations in lipid-regulating enzyme activities in high fat diet-induced obese rats. Male Sprague-Dawley rats were randomly divided into three groups (n=6): a normal diet group (N-control), a high fat diet group (F-control), and a high fat diet group, treated orally with CE (0.25%) in their drinking water (Treatment). After five weeks, CE supplementation tended to reduce body-weight gain and visceral fat in the diet-induced obese rats. The activity of hepatic glucose-6-phosphate dehydrogenase (G6PD) and malic enzyme (ME), responsible for fatty acid synthesis, tended to be lower in the Treatment group compared to the non-treated groups. This finding indicates that the body fat suppressive effects of CE are most likely due to decreases in hepatic fatty acid synthesis. CE supplementation increased hepatic carnitine palmitoyltransferase (CPT) activity, which suggests that β-oxidation was enhanced. In conclusion, CE supplementation suppressed body fat accumulation by attenuating fatty acid synthesis and enhancing β-oxidation through alteration of lipid-regulating enzyme activities.","PeriodicalId":20600,"journal":{"name":"Progress in Nutrition","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47382542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0