Processes最新文献_第4页

Semi-Analytical Closed-Form Solutions of the Ball–Plate Problem 球板问题的半解析封闭式解法

IF 3.5 4区工程技术

Processes Pub Date : 2024-09-13 DOI: 10.3390/pr12091977

Remus-Daniel Ene, Nicolina Pop

引用次数: 0

Innovative and Patented Liposome-Based Drug Carriers 创新型专利脂质体药物载体

IF 3.5 4区工程技术

Processes Pub Date : 2024-09-13 DOI: 10.3390/pr12091970

Snežana Ilić-Stojanović, Suzana Cakić, Nada Nikolić, Slobodan Petrović

{"title":"Innovative and Patented Liposome-Based Drug Carriers","authors":"Snežana Ilić-Stojanović, Suzana Cakić, Nada Nikolić, Slobodan Petrović","doi":"10.3390/pr12091970","DOIUrl":"https://doi.org/10.3390/pr12091970","url":null,"abstract":"Liposome-based drug carriers are multipurpose colloidal drug delivery systems developed mainly for targeted therapy. Researchers have expanded their research on liposomes due to their unique characteristics (e.g., non-toxicity, biodegradability, biocompatibility, and non-immunogenicity). This review summarizes historical advances, from the first scientific papers and patents to the latest inventive solutions, in the field of liposome-based drug carriers and their production processes. Various bibliometric studies on the use of liposomes as drug carriers have been published; nevertheless, they focus on published scientific works rather than patent documents. Patent information is important for the pharmaceutical, nutraceutical, and cosmetic industries because technical knowledge in patent documentation is often not published in any other document. The research in this review was conducted using the Espacenet—European Patent Office database, with keywords and classification codes defined by the International Patent Classification. Innovative formulations, including the usage and administration route, are broadly researched to produce effective and safe drug delivery systems with negligible side effects. Global patenting trends in liposome drug carriers’ production process were also discussed, and this evaluation unifies up-to-date development in this field. Patent database reviews and analyses could help as inspiration for future investigations as well as for problem-solving resources.","PeriodicalId":20597,"journal":{"name":"Processes","volume":"7 1","pages":""},"PeriodicalIF":3.5,"publicationDate":"2024-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142187960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Understanding Perforation Detonation Failure Mechanisms Based on Physicochemical Detection and Simulation Modeling 基于物理化学检测和模拟建模了解穿孔引爆失效机理

IF 3.5 4区工程技术

Processes Pub Date : 2024-09-13 DOI: 10.3390/pr12091971

Chaofeng Chen, Xihe Liu, Dong Ruan, Xueru Chen, Xiangtong Yang, Kun Ning, Zhilong Lian

{"title":"Understanding Perforation Detonation Failure Mechanisms Based on Physicochemical Detection and Simulation Modeling","authors":"Chaofeng Chen, Xihe Liu, Dong Ruan, Xueru Chen, Xiangtong Yang, Kun Ning, Zhilong Lian","doi":"10.3390/pr12091971","DOIUrl":"https://doi.org/10.3390/pr12091971","url":null,"abstract":"With advancements in the exploration and development of deep and ultra-deep oil and gas resources, the number of ultra-deep wells continues to rise globally. This trend places higher demands on testing technology. The combined perforating and testing technique, an established method for deep and ultra-deep wells, faces challenges. Frequent test operation failures due to perforation detonation failure increase down-hole complexity, restricting the timeliness of testing operations. Current methods use mechanical calibration software to calculate the minimum safety factor of the tubing string for safety assessments. However, without a thorough understanding of perforation detonation failure theory, existing mechanical analysis software remains unreliable for assessing well safety during operations. Simply using the safety factor method lacks reliability and cannot explain the causes of perforation detonation failure. This paper examines an ultra-deep well, referred to as TW1, to analyze perforation detonation failure mechanisms. Through metal microstructure examinations, chemical composition analysis, electron microscope scanning, and numerical simulation, the study yields the following insights: (1) The packer mandrel of Well TW1 fractured due to overstress from the detonation waves. (2) Detonation wave propagation patterns along the tubing string during perforation become apparent. (3) Simulation methods reconstruct the perforation detonation process, calculating effective stress at different tubing string positions over time. (4) It introduces an innovative approach for assessing perforation detonation failure mechanisms through a combination of laboratory testing and simulation modeling.","PeriodicalId":20597,"journal":{"name":"Processes","volume":"185 1","pages":""},"PeriodicalIF":3.5,"publicationDate":"2024-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142187961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Development of Replica Molding Processes for Hypervariable Microstructural Components 开发用于超变量微结构部件的复制成型工艺

IF 3.5 4区工程技术

Processes Pub Date : 2024-09-13 DOI: 10.3390/pr12091968

Yung-Jin Weng, Yu-Zhe Gao, Yu-Ming Chen

{"title":"Development of Replica Molding Processes for Hypervariable Microstructural Components","authors":"Yung-Jin Weng, Yu-Zhe Gao, Yu-Ming Chen","doi":"10.3390/pr12091968","DOIUrl":"https://doi.org/10.3390/pr12091968","url":null,"abstract":"The current study investigates the development of a replica molding process for hypervariable microstructures. Initially, the mold deformation theory for these hypervariable microstructures was derived. Based on this theory, a metal material with magnetic properties was selected as the structural material to create a negative Poisson’s ratio (NPR) geometric structure. The experimental results, obtained by fabricating the NPR geometric mold layer with a metal material with adjustable magnetic properties and controlling microstructure deformation indirectly, validate the deformation theory and its predictions. These results demonstrate that the developed molding process, integrated with the magnetic NPR regulation system, exhibits excellent stability and replication capability. In this study, at the zero height (z = 0) position on the interface between the NPR geometric structure layer and the Polydimethylsiloxane (PDMS), the variation becomes more pronounced with increasing distance from the center of the microstructure. Furthermore, the tendency of the function curve varies accordingly. The primary cause is the lack of constraints on the free ends of both sides and the excessive constraints on the intermediate parts. Under the conditions in this study, the maximum ratio of its influence on the radial diameter thickness was 2.1%. This innovative process facilitates the rapid imprinting of microstructural components and offers the advantage of efficient molding.","PeriodicalId":20597,"journal":{"name":"Processes","volume":"1 1","pages":""},"PeriodicalIF":3.5,"publicationDate":"2024-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142188086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bacterial Cellulose in Food Packaging: A Bibliometric Analysis and Review of Sustainable Innovations and Prospects 食品包装中的细菌纤维素：可持续创新与前景的文献计量分析与回顾

IF 3.5 4区工程技术

Processes Pub Date : 2024-09-13 DOI: 10.3390/pr12091975

Aida Aguilera Infante-Neta, Alan Portal D’Almeida, Tiago Lima de Albuquerque

{"title":"Bacterial Cellulose in Food Packaging: A Bibliometric Analysis and Review of Sustainable Innovations and Prospects","authors":"Aida Aguilera Infante-Neta, Alan Portal D’Almeida, Tiago Lima de Albuquerque","doi":"10.3390/pr12091975","DOIUrl":"https://doi.org/10.3390/pr12091975","url":null,"abstract":"The scientific community has explored new packaging materials owing to environmental challenges and pollution from plastic waste. Bacterial cellulose (BC), produced by bacteria like Gluconacetobacter xylinus, shows high potential for food preservation owing to its exceptional mechanical strength, high crystallinity, and effective barrier properties against gases and moisture, making it a promising alternative to conventional plastics. This review highlights recent advances in BC production, particularly agro-industrial residues, which reduce costs and enhance environmental sustainability. Incorporating antimicrobial agents into BC matrices has also led to active packaging solutions that extend food shelf-life and improve safety. A bibliometric analysis reveals a significant increase in research on BC over the last decade, reflecting growing global interest. Key research themes include the development of BC-based composites and the exploration of their antimicrobial properties. Critical areas for future research include improving BC production’s scalability and economic viability and the integration of BC with other biopolymers. These developments emphasize BC’s potential as a sustainable packaging material and its role in the circular economy through waste valorization.","PeriodicalId":20597,"journal":{"name":"Processes","volume":"7 1","pages":""},"PeriodicalIF":3.5,"publicationDate":"2024-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142187964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An Enhanced Multi-Objective Evolutionary Algorithm with Reinforcement Learning for Energy-Efficient Scheduling in the Flexible Job Shop 增强型多目标进化算法与强化学习用于灵活作业车间的节能调度

IF 3.5 4区工程技术

Processes Pub Date : 2024-09-13 DOI: 10.3390/pr12091976

Jinfa Shi, Wei Liu, Jie Yang

{"title":"An Enhanced Multi-Objective Evolutionary Algorithm with Reinforcement Learning for Energy-Efficient Scheduling in the Flexible Job Shop","authors":"Jinfa Shi, Wei Liu, Jie Yang","doi":"10.3390/pr12091976","DOIUrl":"https://doi.org/10.3390/pr12091976","url":null,"abstract":"The study of the flexible job shop scheduling problem (FJSP) is of great importance in the context of green manufacturing. In this paper, with the optimization objectives of minimizing the maximum completion time and the total machine energy consumption, an improved multi-objective evolutionary algorithm with decomposition (MOEA/D) based on reinforcement learning is proposed. Firstly, three initialization strategies are used to generate the initial population in a certain ratio, and four variable neighborhood search strategies are combined to increase the local search capability of the algorithm. Second, a parameter adaptation strategy based on Q-learning is proposed to guide the population to select the optimal parameters to increase diversity. Finally, the performance of the proposed algorithm is analyzed and evaluated by comparing Q-MOEA/D with IMOEA/D and NSGA-II through different sizes of Kacem and BRdata benchmark cases and production examples of automotive engine cooling system manufacturing. The results show that the Q-MOEA/D algorithm outperforms the other two algorithms in solving the energy-efficient scheduling problem for flexible job shops.","PeriodicalId":20597,"journal":{"name":"Processes","volume":"185 1","pages":""},"PeriodicalIF":3.5,"publicationDate":"2024-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142187965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Surrounding Rock Control Technology of Thick Hard Roof and Hard Coal Seam Roadway under Tectonic Stress 构造应力作用下厚硬顶硬煤层巷道围岩控制技术

IF 3.5 4区工程技术

Processes Pub Date : 2024-09-13 DOI: 10.3390/pr12091973

Zhongzong Cao, Honglin Liu, Chengfang Shan, Hongzhi Wang, Haitong Kang

{"title":"Surrounding Rock Control Technology of Thick Hard Roof and Hard Coal Seam Roadway under Tectonic Stress","authors":"Zhongzong Cao, Honglin Liu, Chengfang Shan, Hongzhi Wang, Haitong Kang","doi":"10.3390/pr12091973","DOIUrl":"https://doi.org/10.3390/pr12091973","url":null,"abstract":"In the process of roadway excavation in thick and hard coal seams with a hard roof, the instantaneous release of a large amount of elastic energy accumulated in coal and rock mass causes disasters. Especially under the action of tectonic stress, dynamic disasters of roadway-surrounding rock are extremely strong. Therefore, this paper takes the 110,505 roadway of the Yushuling Coal Mine as the engineering background. Aiming at the serious deformation of roadway-surrounding rock and the problem of strong mine pressure, the deformation mechanism of roadway-surrounding rock is studied by means of theoretical analysis, indoor experimentation, numerical simulation and field testing, and the surrounding rock control technology is proposed. Firstly, the results show that the stress field type of the Yushuling Coal Mine is a σHv type, the azimuth angle of the maximum horizontal principal stress is concentrated in 110.30°~114.12°, the dip angle is −33.04°~−3.43°, and the maximum horizontal principal stress is 1.94~2.76 times of the minimum horizontal principal stress. Secondly, the brittleness index of No. 5 is 0.62; the failure energy release of the surrounding rock compressive energy floor rock sample is up to 150,000 mv * ms. The more the cumulative number of rock samples, the greater the strength, and the more severe the damage. Thirdly, with the increase in tectonic stress, the stress of roadway-surrounding rock is asymmetrically distributed, and the plastic zone develops along the tendency. The maximum range of the plastic zone expands from 4.18 m to 10.19 m. Lastly, according to the deformation characteristics of roadway-surrounding rock, left side > roof > right side > floor, the surrounding rock control technology of ‘asymmetric anchor net cable support + borehole pressure relief’ is proposed, which realizes the effective control of roadway-surrounding rock deformation.","PeriodicalId":20597,"journal":{"name":"Processes","volume":"22 1","pages":""},"PeriodicalIF":3.5,"publicationDate":"2024-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142187999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Lead Ion Adsorption on Glutathione-Modified Carbon 谷胱甘肽改性碳对铅离子的吸附作用

IF 3.5 4区工程技术

Processes Pub Date : 2024-09-13 DOI: 10.3390/pr12091972

Namasivayam Selvanantharajah, Poobalasuntharam Iyngaran, Poobalasingam Abiman, Navaratnarajah Kuganathan

{"title":"Lead Ion Adsorption on Glutathione-Modified Carbon","authors":"Namasivayam Selvanantharajah, Poobalasuntharam Iyngaran, Poobalasingam Abiman, Navaratnarajah Kuganathan","doi":"10.3390/pr12091972","DOIUrl":"https://doi.org/10.3390/pr12091972","url":null,"abstract":"This study explores the adsorption of Pb(II) from aqueous solutions using glutathione-modified carbon powder at room temperature. The graphite powder was modified through oxidation followed by surface immobilization of glutathione. The Pb(II) concentration was measured using square wave anodic stripping voltammetry (SWASV). Experiments were conducted with the following varying initial Pb(II) ion concentrations: 20.72 mg L−1, 41.44 mg L−1, 62.16 mg L−1, 82.88 mg L−1, 103.60 mg L−1, and 124.32 mg L−1. The effect of varying the glutathione-modified carbon powder dosage (12.5 mg, 25.0 mg, 50.0 mg, 75.0 mg, and 100.0 mg) on Pb(II) uptake was studied. The adsorption data were modeled using the Freundlich isotherm, resulting in a regression coefficient (R2) of 0.96, which signifies a good fit. The Freundlich constants obtained were KF = 3.54 × 10−5 (adsorption capacity) and n = 1.56 (adsorption intensity). At optimal conditions (10.0 mL of 20.72 mg L−1 Pb(II) solution with 100.0 mg of glutathione-modified carbon powder), the adsorption efficiency was 96.3%. The glutathione-modified carbon powder exhibits a high capacity for adsorbing Pb(II) from aqueous solutions.","PeriodicalId":20597,"journal":{"name":"Processes","volume":"8 1","pages":""},"PeriodicalIF":3.5,"publicationDate":"2024-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142187962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of Various Drying Methods for Mexican Yahualica chili: Drying Characteristics and Quality Assessment 墨西哥 Yahualica 辣椒各种干燥方法的评估：干燥特性和质量评估

IF 3.5 4区工程技术

Processes Pub Date : 2024-09-13 DOI: 10.3390/pr12091969

Diana Paola García-Moreira, Neith Pacheco, Harumi Hernández-Guzmán, Younes Bahammou, Zakaria Tagnamas, Ivan Moreno, Erick César López-Vidaña

引用次数: 0

Finite Element Analysis of Laminar Natural Convection in a Differentially Heated Porous Cavity Using the Darcy–Brinkman Model 使用达西-布林克曼模型对不同加热多孔空腔中的层流自然对流进行有限元分析

IF 3.5 4区工程技术

Processes Pub Date : 2024-09-13 DOI: 10.3390/pr12091974

Benabderrahmane Farhat, Noureddine Kaid, Sultan Alqahtani, Younes Menni, Badr M. Alshammari, Lioua Kolsi

{"title":"Finite Element Analysis of Laminar Natural Convection in a Differentially Heated Porous Cavity Using the Darcy–Brinkman Model","authors":"Benabderrahmane Farhat, Noureddine Kaid, Sultan Alqahtani, Younes Menni, Badr M. Alshammari, Lioua Kolsi","doi":"10.3390/pr12091974","DOIUrl":"https://doi.org/10.3390/pr12091974","url":null,"abstract":"This study delves into the convective heat transfer phenomena within a square cavity that houses a porous medium, analyzing the effects of Darcy (Da) and Rayleigh (Ra) numbers on the thermal and fluid dynamic behavior within the system. Utilizing a combination of computational fluid dynamics (CFD) and the finite element method (FEM), the research focuses on steady-state, laminar flow conditions in two dimensions. The cavity, which is impermeable at its boundaries, contains a centrally located square region filled with a porous, isotropic material. The thermal environment is controlled with insulated horizontal walls and vertically positioned walls that experience sinusoidal temperature variations. The study examines how variations in the permeability of the porous medium (Da numbers ranging from 10−1 to 10−4) and the buoyancy-driven flow strength (Ra numbers spanning from 102 to 105) influence the velocity fields and heat transfer rates, with results expressed through Nusselt number (Nu) distributions. The findings reveal that higher Ra numbers, particularly at 105, significantly intensify convection within the cavity, thereby boosting local rates of heat transfer, especially in the central vertical section. The research identifies that optimal flow resistance in the porous medium occurs within the Da number range of 10−3 to 10−4. These insights are critical for advancing thermal management techniques, particularly in the natural cooling of electronic devices and improving insulation methods.","PeriodicalId":20597,"journal":{"name":"Processes","volume":"84 1","pages":""},"PeriodicalIF":3.5,"publicationDate":"2024-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142187963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0