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Poster Presentations - Proffered Abstracts最新文献

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Abstract P157: Targeting Trop2 for treatment of prostate and breast cancer P157:靶向Trop2治疗前列腺癌和乳腺癌
Poster Presentations - Proffered Abstracts Pub Date : 2021-12-01 DOI: 10.1158/1535-7163.targ-21-p157
Tanya Stoyanova
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引用次数: 0
Abstract P211: The investigational chemoprotection drug ALRN-6924, a dual inhibitor of MDMX and MDM2, shows potential for radioprotection 摘要:正在研究的化学保护药物ALRN-6924是MDMX和MDM2的双重抑制剂，具有潜在的放射保护作用
Poster Presentations - Proffered Abstracts Pub Date : 2021-12-01 DOI: 10.1158/1535-7163.targ-21-p211
A. Annis, D. Sutton, M. Aivado, V. Vukovic
{"title":"Abstract P211: The investigational chemoprotection drug ALRN-6924, a dual inhibitor of MDMX and MDM2, shows potential for radioprotection","authors":"A. Annis, D. Sutton, M. Aivado, V. Vukovic","doi":"10.1158/1535-7163.targ-21-p211","DOIUrl":"https://doi.org/10.1158/1535-7163.targ-21-p211","url":null,"abstract":"","PeriodicalId":20348,"journal":{"name":"Poster Presentations - Proffered Abstracts","volume":"4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84916152","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Abstract P198: MDNA11 is a long-acting ‘beta-only’ IL-2 agonist that demonstrates a safe and durable anti-tumor immune response 摘要:MDNA11是一种长效的“β -only”IL-2激动剂，具有安全持久的抗肿瘤免疫应答
Poster Presentations - Proffered Abstracts Pub Date : 2021-12-01 DOI: 10.1158/1535-7163.targ-21-p198
M. To, F. Merchant, M. Muhsin, Carole L. Galligan, L. Pearce, P. Lloyd, R. Merchant
{"title":"Abstract P198: MDNA11 is a long-acting ‘beta-only’ IL-2 agonist that demonstrates a safe and durable anti-tumor immune response","authors":"M. To, F. Merchant, M. Muhsin, Carole L. Galligan, L. Pearce, P. Lloyd, R. Merchant","doi":"10.1158/1535-7163.targ-21-p198","DOIUrl":"https://doi.org/10.1158/1535-7163.targ-21-p198","url":null,"abstract":"","PeriodicalId":20348,"journal":{"name":"Poster Presentations - Proffered Abstracts","volume":"25 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81614283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Abstract P050: Trial in progress: A phase 2 multicenter study of autologous tumor-infiltrating lymphocyte (TIL, LN-145) cell therapy in patients with metastatic non-small cell lung cancer (mNSCLC) P050:正在进行的试验:自体肿瘤浸润淋巴细胞(TIL, LN-145)细胞治疗转移性非小细胞肺癌(mNSCLC)患者的2期多中心研究
Poster Presentations - Proffered Abstracts Pub Date : 2021-12-01 DOI: 10.1158/1535-7163.targ-21-p050
E. Massarelli, S. Samakoglu, V. Gontcharova, Guang Chen, M. Jagasia, F. Finckenstein, A. Sukari
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引用次数: 0
Abstract P097: Comparative single cell transcriptome profiling of primary tumors, CTCs and metastatic sites from a bladder cancer PDX model P097:膀胱癌PDX模型原发肿瘤、ctc和转移部位的单细胞转录组分析比较
Poster Presentations - Proffered Abstracts Pub Date : 2021-12-01 DOI: 10.1158/1535-7163.targ-21-p097
T. Vilimas, B. Fullmer, Alyssa K. Chapman, Li Chen, Ting-Chia Chang, R. Pauly, Biswajit Das, C. Karlovich, Yvonne A. Evrard, H. Stotler, Michelle M. Gottholm-Ahalt, Tara Grinnage-Pulley, M. Hollingshead, J. Doroshow, P. Williams
{"title":"Abstract P097: Comparative single cell transcriptome profiling of primary tumors, CTCs and metastatic sites from a bladder cancer PDX model","authors":"T. Vilimas, B. Fullmer, Alyssa K. Chapman, Li Chen, Ting-Chia Chang, R. Pauly, Biswajit Das, C. Karlovich, Yvonne A. Evrard, H. Stotler, Michelle M. Gottholm-Ahalt, Tara Grinnage-Pulley, M. Hollingshead, J. Doroshow, P. Williams","doi":"10.1158/1535-7163.targ-21-p097","DOIUrl":"https://doi.org/10.1158/1535-7163.targ-21-p097","url":null,"abstract":"","PeriodicalId":20348,"journal":{"name":"Poster Presentations - Proffered Abstracts","volume":"67 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79634316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Abstract P100: Use of a novel checkpoint inhibitor peptide ligand in a first-in-human phase 1 trial for adults with recurrent glioblastoma P100:一种新的检查点抑制剂肽配体在成人复发性胶质母细胞瘤的首次人体1期试验中使用
Poster Presentations - Proffered Abstracts Pub Date : 2021-12-01 DOI: 10.1158/1535-7163.targ-21-p100
M. Olin, G. Pluhar, Ingunn M. Stromnes, Anne A Eaton, Shannon Lynn, Emily G Greengard, C. Moertel
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引用次数: 0
Abstract P154: Genomic profiling and matched therapy for recurrent or metastatic salivary gland neoplasms. Results from the matched cohort of the GEMS-001 clinical trial P154:复发或转移性唾液腺肿瘤的基因组分析和匹配治疗。来自GEMS-001临床试验匹配队列的结果
Poster Presentations - Proffered Abstracts Pub Date : 2021-12-01 DOI: 10.1158/1535-7163.targ-21-p154
A. Hernando-Calvo, E. Malone, D. Dai, A. Prawira, I. Weinreb, A. Eliason, Angela Rodriguez, K. Lajkosz, S. Jennings, A. Spreafico, L. Siu, A. Hansen
{"title":"Abstract P154: Genomic profiling and matched therapy for recurrent or metastatic salivary gland neoplasms. Results from the matched cohort of the GEMS-001 clinical trial","authors":"A. Hernando-Calvo, E. Malone, D. Dai, A. Prawira, I. Weinreb, A. Eliason, Angela Rodriguez, K. Lajkosz, S. Jennings, A. Spreafico, L. Siu, A. Hansen","doi":"10.1158/1535-7163.targ-21-p154","DOIUrl":"https://doi.org/10.1158/1535-7163.targ-21-p154","url":null,"abstract":"","PeriodicalId":20348,"journal":{"name":"Poster Presentations - Proffered Abstracts","volume":"4 3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79721947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Abstract P264: Targeting oxygen metabolism reduces hypoxia in the tumor microenvironment of a syngeneic mouse model 摘要P264:靶向氧代谢可减少同基因小鼠肿瘤微环境中的缺氧
Poster Presentations - Proffered Abstracts Pub Date : 2021-12-01 DOI: 10.1158/1535-7163.targ-21-p264
D. Boreel, P. Span, H. Peters, R. V. D. van den Bijgaart, S. Heskamp, G. Adema, J. Bussink
{"title":"Abstract P264: Targeting oxygen metabolism reduces hypoxia in the tumor microenvironment of a syngeneic mouse model","authors":"D. Boreel, P. Span, H. Peters, R. V. D. van den Bijgaart, S. Heskamp, G. Adema, J. Bussink","doi":"10.1158/1535-7163.targ-21-p264","DOIUrl":"https://doi.org/10.1158/1535-7163.targ-21-p264","url":null,"abstract":"","PeriodicalId":20348,"journal":{"name":"Poster Presentations - Proffered Abstracts","volume":"25 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80768632","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Abstract P129: Ketogenic diet (KD) and targeting Warburg effect: Apparent toxicity of KD combination with 2-deoxy-D-glucose 摘要P129:生酮饮食(KD)和靶向Warburg效应:KD联合2-脱氧-d -葡萄糖的明显毒性
Poster Presentations - Proffered Abstracts Pub Date : 2021-12-01 DOI: 10.1158/1535-7163.targ-21-p129
Rafal Zieliński, M. Poimenidou, M. Khuong, Krzysztof Grela, Roberto Cárdenas-Zúñiga, S. Skóra, I. Fokt, Mike Gagea, Jody Swain, Sigmund Zhou, W. Priebe
{"title":"Abstract P129: Ketogenic diet (KD) and targeting Warburg effect: Apparent toxicity of KD combination with 2-deoxy-D-glucose","authors":"Rafal Zieliński, M. Poimenidou, M. Khuong, Krzysztof Grela, Roberto Cárdenas-Zúñiga, S. Skóra, I. Fokt, Mike Gagea, Jody Swain, Sigmund Zhou, W. Priebe","doi":"10.1158/1535-7163.targ-21-p129","DOIUrl":"https://doi.org/10.1158/1535-7163.targ-21-p129","url":null,"abstract":"","PeriodicalId":20348,"journal":{"name":"Poster Presentations - Proffered Abstracts","volume":"93 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83158562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Abstract P220: Reactivation of the tumor suppressor SPARC in bladder cancer by verteporfin P220:维替泊芬对膀胱癌肿瘤抑制因子SPARC的再激活作用
Poster Presentations - Proffered Abstracts Pub Date : 2021-12-01 DOI: 10.1158/1535-7163.targ-21-p220
N. Said
{"title":"Abstract P220: Reactivation of the tumor suppressor SPARC in bladder cancer by verteporfin","authors":"N. Said","doi":"10.1158/1535-7163.targ-21-p220","DOIUrl":"https://doi.org/10.1158/1535-7163.targ-21-p220","url":null,"abstract":"","PeriodicalId":20348,"journal":{"name":"Poster Presentations - Proffered Abstracts","volume":"247 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81442260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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