Preventive medicine最新文献_第3页

Prospective association of internet gaming disorder with subsequent first suicidal attempt: A large-scale school-based study of Chinese adolescents 网络游戏障碍与随后的第一次自杀企图的前瞻性关联：一项针对中国青少年的大规模学校研究

IF 3.2 2区医学

Preventive medicine Pub Date : 2025-08-27 DOI: 10.1016/j.ypmed.2025.108396

Pu Peng , Zhangming Chen , Silan Ren , Yudiao Liang , Youguo Tan , Xiaogang Chen , Jinsong Tang , Yanhui Liao

{"title":"Prospective association of internet gaming disorder with subsequent first suicidal attempt: A large-scale school-based study of Chinese adolescents","authors":"Pu Peng , Zhangming Chen , Silan Ren , Yudiao Liang , Youguo Tan , Xiaogang Chen , Jinsong Tang , Yanhui Liao","doi":"10.1016/j.ypmed.2025.108396","DOIUrl":"10.1016/j.ypmed.2025.108396","url":null,"abstract":"<div><h3>Objectives</h3><div>While Internet Gaming Disorder (IGD) is a known risk factor for suicidal ideation, longitudinal evidence linking it to suicidal attempt remains scarce. This study investigates whether IGD severity independently predicts first-onset suicidal attempt in adolescents.</div></div><div><h3>Methods</h3><div>A school-based cohort of 87,390 Chinese adolescents (baseline age: 14.2 ± 1.5 years) was followed for one year (2022−2023). The severity of IGD was assessed using the Internet Gaming Disorder Scale-Short Form (IGDS9-SF). The primary analysis utilized multivariable logistic regression to examine the association between the continuous IGDS9-SF score and incident suicidal attempts, adjusting for demographics, mental health symptoms, and baseline suicidal ideation. Sensitivity analyses included examining categorical IGD status, individual symptom contributions, non-linearity testing, and <em>E</em>-value calculation.</div></div><div><h3>Results</h3><div>A total of 6620 (7.6 %) adolescents reported an incident suicidal attempt. Each one-point increase in the IGDS9-SF score raised the odds of a first suicidal attempt by 2 % (Adjusted Odds Ratio = 1.02, 95 % CI = 1.02–1.03). The association was robust across all sensitivity analyses, demonstrating a linear trend and resilience to unmeasured confounding (<em>E</em>-value ≥2.24).</div></div><div><h3>Conclusions</h3><div>IGD severity is an independent, dose-dependent associated factor for suicidal attempt in adolescents. Measuring IGD severity might be a valuable strategy for identifying adolescents at risk.</div></div>","PeriodicalId":20339,"journal":{"name":"Preventive medicine","volume":"199 ","pages":"Article 108396"},"PeriodicalIF":3.2,"publicationDate":"2025-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144908472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Suicide trends and patterns in young adults across global regions and selected major countries worldwide from the World Health Organization mortality database, 2001–2020 2001-2020年世界卫生组织死亡率数据库中全球各区域和选定主要国家青年的自杀趋势和模式

IF 3.2 2区医学

Preventive medicine Pub Date : 2025-08-26 DOI: 10.1016/j.ypmed.2025.108397

Minjae Choi , Sujeong Yu , Hanul Park , Joshua Kirabo Sempungu , Joon Hee Han , Eun Hae Lee , Yo Han Lee

{"title":"Suicide trends and patterns in young adults across global regions and selected major countries worldwide from the World Health Organization mortality database, 2001–2020","authors":"Minjae Choi , Sujeong Yu , Hanul Park , Joshua Kirabo Sempungu , Joon Hee Han , Eun Hae Lee , Yo Han Lee","doi":"10.1016/j.ypmed.2025.108397","DOIUrl":"10.1016/j.ypmed.2025.108397","url":null,"abstract":"<div><h3>Objective</h3><div>We aimed to analyze trends and patterns of suicide among young adults worldwide, 2001–2020.</div></div><div><h3>Methods</h3><div>We used the World Health Organization Mortality Database to extract suicide deaths for individuals aged 20–39 years from 55 countries with valid and medium/high-quality data, 2001–2020. Suicide rates were calculated by sex, age group, and suicide method across global regions and countries. We conducted a joinpoint regression analysis to identify trends and changes in suicide rates.</div></div><div><h3>Results</h3><div>Marked geographical disparities were found in suicide trends by sex and method. In the Americas, suicide rates recently increased across all subregions, particularly in the North American region. In contrast, most European subregions showed decreasing trends in suicide rates in both males and females, except for North Europe. In Asia, suicide trends varied across subregions, with marked reductions in Central Asia among males and fluctuations in East Asia among females. Hanging was the most commonly used method across all countries, except in the US, where firearms were more used, particularly among males. Other major methods, such as poisoning and gas poisoning, showed changes in trends.</div></div><div><h3>Conclusions</h3><div>Suicide trends among young adults varied by sex, method, and country, with concerning increases or persistently high rates in some countries.</div></div>","PeriodicalId":20339,"journal":{"name":"Preventive medicine","volume":"200 ","pages":"Article 108397"},"PeriodicalIF":3.2,"publicationDate":"2025-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144926756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association of sustained extremely low income and income decrease with the risk of Parkinson's disease: A population-based nationwide cohort study in Korea 持续极低收入和收入减少与帕金森病风险的关系：韩国一项基于人群的全国队列研究

IF 3.2 2区医学

Preventive medicine Pub Date : 2025-08-25 DOI: 10.1016/j.ypmed.2025.108394

Seo Yeon Yoon , Kyungdo Han , Kyu-Na Lee , Jee Hyun Suh , Ga Eun Nam

{"title":"Association of sustained extremely low income and income decrease with the risk of Parkinson's disease: A population-based nationwide cohort study in Korea","authors":"Seo Yeon Yoon , Kyungdo Han , Kyu-Na Lee , Jee Hyun Suh , Ga Eun Nam","doi":"10.1016/j.ypmed.2025.108394","DOIUrl":"10.1016/j.ypmed.2025.108394","url":null,"abstract":"<div><h3>Objective</h3><div>Previous studies on the association between income and Parkinson's disease assessed income status at a single time point, without considering changes over time. This study aimed to evaluate the longitudinal association between various income dynamics and the risk of Parkinson's disease.</div></div><div><h3>Methods</h3><div>We used the Korean National Health Insurance Service data, enrolling 2,644,550 individuals who participated in the 2012 National Health Screening Program. The national health insurance premium was used as a proxy measure of income, with four levels (quartile 1 [low] to 4 [high]). Additionally, Medical Aid was classified as extremely low-income. Parkinson's disease was defined using the ICD-10 code (G20) and the rare intractable disease registration code (V124). Cox proportional hazards models were used to assess the longitudinal association between income status and Parkinson's disease rate.</div></div><div><h3>Results</h3><div>During the study period, the incidence rate of Parkinson's disease was 27.13 per 100,000 person-years. A dose-response association between the cumulative number of years in the extremely low-income status and Parkinson's disease rate was identified (P for trend <0.001). A decrease in income from 2008 to 2012 to extremely low-income from quartile 1 (HR = 2.19, 95 % CI 1.55, 3.09), quartile 2 (HR = 2.56, 95 % CI 1.75, 3.74), or quartile 3 (HR = 2.20, 95 % CI 1.24, 3.88) was associated with more than a two-fold increased Parkinson's disease rate compared to individuals with sustained income status.</div></div><div><h3>Conclusions</h3><div>Individuals with sustained extremely low income over 5 consecutive years and those who experienced a decrease in income to this status were at a significantly higher rate of developing Parkinson's disease.</div></div>","PeriodicalId":20339,"journal":{"name":"Preventive medicine","volume":"199 ","pages":"Article 108394"},"PeriodicalIF":3.2,"publicationDate":"2025-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144908480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Maintaining healthy lifestyle behaviours in the era of social media: Challenges and solutions 在社交媒体时代保持健康的生活方式：挑战和解决方案

IF 3.2 2区医学

Preventive medicine Pub Date : 2025-08-24 DOI: 10.1016/j.ypmed.2025.108395

Jean-Philippe Chaput , Allana G. LeBlanc

{"title":"Maintaining healthy lifestyle behaviours in the era of social media: Challenges and solutions","authors":"Jean-Philippe Chaput , Allana G. LeBlanc","doi":"10.1016/j.ypmed.2025.108395","DOIUrl":"10.1016/j.ypmed.2025.108395","url":null,"abstract":"<div><h3>Objective</h3><div>To examine the dual role of social media in influencing lifestyle behaviours relevant to chronic disease prevention and to propose strategies that align digital environments with public health objectives.</div></div><div><h3>Methods</h3><div>This commentary synthesizes recent evidence on the associations between social media use and health behaviours, including physical activity, nutrition, sleep, and sedentary time. It draws on research from public health, behavioural science, and digital media studies to highlight both risks and opportunities.</div></div><div><h3>Results</h3><div>Evidence shows that prolonged and unregulated social media engagement contributes to increased sedentary time, sleep disruption, poor dietary choices, exposure to targeted marketing of unhealthy products, unrealistic body ideals, and health misinformation. Conversely, social media can be harnessed to promote behaviour change through scalable interventions such as social support, self-monitoring, and goal setting.</div></div><div><h3>Conclusions</h3><div>Addressing the challenges posed by social media requires coordinated, multi-level strategies. These include redesigning digital environments with health-promoting defaults, regulating harmful commercial exposures, leveraging platforms for evidence-based health promotion, strengthening digital literacy, and introducing school-based smartphone restrictions. Aligning platform design and governance with public health goals is essential to mitigating risks, supporting healthy behaviours, and improving population health outcomes.</div></div>","PeriodicalId":20339,"journal":{"name":"Preventive medicine","volume":"199 ","pages":"Article 108395"},"PeriodicalIF":3.2,"publicationDate":"2025-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144902918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association between midlife intake of ultra-processed foods and later-life subjective cognitive complaints: Evidence from the new York University women's health study 中年摄入超加工食品与晚年主观认知抱怨之间的关系：来自纽约大学妇女健康研究的证据

IF 3.2 2区医学

Preventive medicine Pub Date : 2025-08-21 DOI: 10.1016/j.ypmed.2025.108390

Kejia Zhang , Fen Wu , Tess V. Clendenen , Yelena Afanasyeva , Yian Gu , Karen L. Koenig , Anne Zeleniuch-Jacquotte , Yu Chen

{"title":"Association between midlife intake of ultra-processed foods and later-life subjective cognitive complaints: Evidence from the new York University women's health study","authors":"Kejia Zhang , Fen Wu , Tess V. Clendenen , Yelena Afanasyeva , Yian Gu , Karen L. Koenig , Anne Zeleniuch-Jacquotte , Yu Chen","doi":"10.1016/j.ypmed.2025.108390","DOIUrl":"10.1016/j.ypmed.2025.108390","url":null,"abstract":"<div><h3>Objective</h3><div>Research into risk factors for subjective cognitive complaints (SCCs) may offer insight into the etiology and prevention of Alzheimer's disease. Ultra-processed foods (UPFs) contain food additives that improve palatability and processed raw materials. Evidence is limited on the role of mid-life UPF intake in the development of late-life SCCs.</div></div><div><h3>Methods</h3><div>We included 5119 participants who responded to the 2018 or 2020 follow-up of the New York University Women's Health Study, a prospective cohort of 14,274 women recruited in New York City, United States, in 1985–91. Data on diet were collected at baseline using a validated modified Block food frequency questionnaire. Energy-adjusted total intake of UPFs and subgroups of UPFs, defined following the nova guidelines, were estimated using the residual method.</div></div><div><h3>Results</h3><div>The odds ratios (ORs) and 95 % confidence intervals (CIs) for reporting ≥2 SCCs were 1.15 (0.94–1.39), 1.06 (0.87–1.30), 1.20 (0.99–1.46), and 1.24 (1.02–1.51) for women in the 2nd, 3rd, 4th, and 5th quintiles of energy-adjusted UPF intake, respectively, compared to those in the bottom quintile (p-trend = 0.02). The associations were similar in sensitivity analyses using Multiple Imputation and Inverse Probability Weighting to account for potential selection bias.</div></div><div><h3>Conclusions</h3><div>Higher UPF intakes in midlife were associated with higher odds of late-life SCCs in women.</div></div>","PeriodicalId":20339,"journal":{"name":"Preventive medicine","volume":"200 ","pages":"Article 108390"},"PeriodicalIF":3.2,"publicationDate":"2025-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144933915","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Inequities in food security by sexual orientation in the United States 美国性取向导致的食品安全不平等

IF 3.2 2区医学

Preventive medicine Pub Date : 2025-08-20 DOI: 10.1016/j.ypmed.2025.108391

Alexandra Balshi , John P. Dempsey , Hannah R. Thompson , Mary W. Montgomery

{"title":"Inequities in food security by sexual orientation in the United States","authors":"Alexandra Balshi , John P. Dempsey , Hannah R. Thompson , Mary W. Montgomery","doi":"10.1016/j.ypmed.2025.108391","DOIUrl":"10.1016/j.ypmed.2025.108391","url":null,"abstract":"<div><h3>Objective</h3><div>To determine if sexual minority (gay, lesbian, bisexual, or another [LGB+] sexual orientation) identity independently contributes to food insecurity while accounting for other social drivers of health (SDoH) like race, education, employment, supplemental nutrition assistance program (SNAP) participation, and mental illness.</div></div><div><h3>Methods</h3><div>We performed multivariate logistic regression of 2019–2023 National Health Interview Surveys to determine any relationship between LGB+ identity and 30-day food security scale responses.</div></div><div><h3>Results</h3><div>We included 130,656 participants, representing 235,728,318 Americans by weighted sampling. Among those eligible, there was no difference in SNAP utilization between LGB+ and heterosexual individuals (odds ratio: 1.12, 95 % confidence interval: 0.97–1.30). However, LGB+ individuals had 1.53 times higher odds of very low food security (95 % confidence interval: 1.31–1.79) even after adjusting for SDoH and mental illness.</div></div><div><h3>Conclusion</h3><div>Despite similar SNAP enrollment, LGB+ individuals remain disproportionately food insecure, suggesting that structural or systemic barriers not addressed through federal food assistance programs contribute to elevated risk.</div></div>","PeriodicalId":20339,"journal":{"name":"Preventive medicine","volume":"199 ","pages":"Article 108391"},"PeriodicalIF":3.2,"publicationDate":"2025-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144889692","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Electronic cigarettes and pregnancy: A social media content analysis. 电子烟与怀孕：一项社交媒体内容分析。

IF 3.2 2区医学

Preventive medicine Pub Date : 2025-08-13 DOI: 10.1016/j.ypmed.2025.108387

Grace Kong, Rachel R Ouellette, Amanda de la Noval, Christina N Kyriakos, Vanessa Ponte, Elise E DeVito

{"title":"Electronic cigarettes and pregnancy: A social media content analysis.","authors":"Grace Kong, Rachel R Ouellette, Amanda de la Noval, Christina N Kyriakos, Vanessa Ponte, Elise E DeVito","doi":"10.1016/j.ypmed.2025.108387","DOIUrl":"10.1016/j.ypmed.2025.108387","url":null,"abstract":"<p><strong>Objective: </strong>Electronic cigarette (e-cigarette) use during pregnancy is a polarizing and complex public health topic. We examined social media content on e-cigarette use during pregnancy.</p><p><strong>Methods: </strong>We content analyzed 170 TikTok posts about e-cigarettes and pregnancy in 2023. We coded message valence (anti-, pro-, mixed/unclear/neutral), messenger characteristics (age, gender, pregnancy status, healthcare provider status, e-cigarette and cigarette use), geographic origin, and engagement metrics (likes, favorites, shares, downloads, comments, followers). We assessed whether engagement and message valence differed by messenger and post characteristics using Chi-Square and Kruskal-Wallis tests.</p><p><strong>Results: </strong>Posts included 55 % (n = 93) anti-, 32.4 % (n = 55) mixed/unclear/neutral, and 12.9 % (n = 22) pro-e-cigarette use during pregnancy messages. Messenger characteristics included 90.6 % (n = 144) female, 53.5 % (n = 85) 18 to 30 years old, 40.9 % (n = 65) pregnant, 7.5 % (n = 12) healthcare providers. Geographic origin included 66.5 % (n = 113) from the United States and 22.9 % (n = 39) from the United Kingdom. Engagement was high, with some videos receiving over 2 million \"plays\" and 500 thousand \"likes.\" Posts by healthcare providers and messengers over 45 years old had more followers (ps < 0.001). Posts with messengers who quit e-cigarettes, from the US, and 18-45 years old were more likely to contain anti-e-cigarette content, whereas posts from the United Kingdom were more likely to have pro-e-cigarette content (ps ≤ 0.001).</p><p><strong>Conclusions: </strong>A wide range of content on e-cigarette use and pregnancy was observed on TikTok. Future research is needed to understand how pregnant individuals navigate this content. Healthcare providers may be effective messengers for promoting e-cigarette cessation during pregnancy on social media.</p>","PeriodicalId":20339,"journal":{"name":"Preventive medicine","volume":" ","pages":"108387"},"PeriodicalIF":3.2,"publicationDate":"2025-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144859545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Adverse childhood experiences, resilience, and substance use during early pregnancy 不良的童年经历、恢复力和怀孕早期的药物使用。

IF 3.2 2区医学

Preventive medicine Pub Date : 2025-08-13 DOI: 10.1016/j.ypmed.2025.108388

Kelly C. Young-Wolff , Mariah S. Wood , Sara R. Adams , Monique B. Does , Deborah Ansley , Carley Castellanos , Maria T. Koshy , Carey R. Watson

{"title":"Adverse childhood experiences, resilience, and substance use during early pregnancy","authors":"Kelly C. Young-Wolff , Mariah S. Wood , Sara R. Adams , Monique B. Does , Deborah Ansley , Carley Castellanos , Maria T. Koshy , Carey R. Watson","doi":"10.1016/j.ypmed.2025.108388","DOIUrl":"10.1016/j.ypmed.2025.108388","url":null,"abstract":"<div><h3>Objective</h3><div>Adverse childhood experiences (ACEs) are common risk factors for unhealthy behaviors and poor health outcomes throughout the life course, but their relationship with prenatal substance use is understudied. This retrospective cohort study included 44,284 patients with pregnancies between January 1, 2022, and June 28, 2024, in a large healthcare system in Northern California, United States of America with universal screening for ACEs, resilience, and substance use during early pregnancy.</div></div><div><h3>Methods</h3><div>Multivariable regression models examined the relationship between ACEs and prenatal substance use and tested whether resilience moderated these associations.</div></div><div><h3>Results</h3><div>Pregnant individuals with a greater number of ACEs had lower resilience, were younger, more likely to be Black, Non-Hispanic White, or Hispanic, and live in an area with greater neighborhood deprivation. In adjusted models, compared to those without ACEs, those with ACEs had a higher adjusted prevalence of prenatal alcohol use, cannabis use, nicotine use, pharmaceutical opioid use, stimulant use, and multiple substance use. Low resilience was independently associated with an increased prevalence of prenatal substance use.</div></div><div><h3>Conclusions</h3><div>Results indicate that routine screening for ACEs may help identify pregnant individuals at risk for prenatal substance use, allowing for earlier linkage to resources and potentially improved maternal and child outcomes.</div></div>","PeriodicalId":20339,"journal":{"name":"Preventive medicine","volume":"199 ","pages":"Article 108388"},"PeriodicalIF":3.2,"publicationDate":"2025-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144859544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association between an active lifestyle and reduced incidence of obesity-related cancers in the Seguimiento Universidad de Navarra cohort Seguimiento university de Navarra队列中积极的生活方式与减少肥胖相关癌症发病率之间的关系

IF 3.2 2区医学

Preventive medicine Pub Date : 2025-08-08 DOI: 10.1016/j.ypmed.2025.108386

Maite Bastyr-Diego , Maria Barbería-Latasa , Maria Olmedo , Alfredo Gea , Maira Bes-Rastrollo , Miguel Ángel Martínez-González , Estefania Toledo

{"title":"Association between an active lifestyle and reduced incidence of obesity-related cancers in the Seguimiento Universidad de Navarra cohort","authors":"Maite Bastyr-Diego , Maria Barbería-Latasa , Maria Olmedo , Alfredo Gea , Maira Bes-Rastrollo , Miguel Ángel Martínez-González , Estefania Toledo","doi":"10.1016/j.ypmed.2025.108386","DOIUrl":"10.1016/j.ypmed.2025.108386","url":null,"abstract":"<div><h3>Objective</h3><div>To assess whether physical activity, sedentary behavior, and an active lifestyle score, combining physical activity and sedentary behavior, are associated with developing obesity-related cancers (ORCs).</div></div><div><h3>Methods</h3><div>From 1999 through 2022, a cohort of Spanish university graduates was followed using biennial questionnaires collecting data on sociodemographic characteristics, clinical diagnoses, and lifestyle factors. We used a previously validated questionnaire to assess physical and sedentary activities (television watching+sitting time), from which we estimated an eight-item active lifestyle score. Cancer incidence was confirmed with medical records and the National Death Index. Multivariable-adjusted hazard ratios (HRs) were estimated with Cox regression models.</div></div><div><h3>Results</h3><div>Higher adherence to the active lifestyle score nearly halved the risk of ORCs (HR high vs. low 0.45 (95 %CI 0.27–0.73)). The HR in quartile four (Q4) of leisure-time physical activity was 0.54 (95 %CI 0.37–0.80) compared to Q1. The HR per +1-point increase in the score was 0.88 (95 %CI 0.81–0.95). No significant association was observed between television watching and ORCs risk.</div></div><div><h3>Conclusions</h3><div>A higher active lifestyle score was associated with a decreased risk of ORCs. These findings may aid public health organizations in refining recommendations in ORC prevention to include interventions focused on combining increased physical activity and lowered sedentary behavior.</div></div>","PeriodicalId":20339,"journal":{"name":"Preventive medicine","volume":"199 ","pages":"Article 108386"},"PeriodicalIF":3.2,"publicationDate":"2025-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144817274","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The heterogeneity of youth at risk of prediabetes and diabetes: A latent class analysis of a United States national sample 青少年糖尿病前期和糖尿病风险的异质性：美国国家样本的潜在分类分析。

IF 3.2 2区医学

Preventive medicine Pub Date : 2025-08-07 DOI: 10.1016/j.ypmed.2025.108384

Catherine McDonough , Yan Chak Li , Gaurav Pandey , Nita Vangeepuram , Bian Liu

{"title":"The heterogeneity of youth at risk of prediabetes and diabetes: A latent class analysis of a United States national sample","authors":"Catherine McDonough , Yan Chak Li , Gaurav Pandey , Nita Vangeepuram , Bian Liu","doi":"10.1016/j.ypmed.2025.108384","DOIUrl":"10.1016/j.ypmed.2025.108384","url":null,"abstract":"<div><h3>Objective</h3><div>Prediabetes and diabetes are complex conditions associated with interrelated factors from multiple domains, including lifestyle, health, and sociodemographic status. We aimed to identify youth subgroups with co-occurring features from these domains to inform prevention and intervention efforts.</div></div><div><h3>Methods</h3><div>We analyzed data from 1278 adolescents (ages 12–17 years) from the 2011–2018 United States National Health and Nutrition Examination Surveys. Prediabetes/diabetes was defined using hemoglobin A1c (≥5.7 mg/dL) and/or fasting plasma glucose (≥100 mg/dL). We applied latent class analysis of physical activity, diet quality, screen time, and body mass index (BMI) identified subgroups adjusting for sociodemographic factors. Associations between latent class membership and prediabetes/diabetes were assessed using survey-weighted logistic regression.</div></div><div><h3>Results</h3><div>Four classes emerged: High BMI and unhealthy lifestyle (37.5 %), Healthy BMI and physically active (24.7 %), Healthy BMI and lifestyle (16.0 %), and Average BMI and lifestyle (21.8 %). Compared to youth in the High BMI and unhealthy lifestyle class, youth in the other three classes all had lower odds of prediabetes/diabetes, where the adjusted odds ratio was 0.56 (95 % CI: 0.33–0.95) for youth of the Healthy BMI and active class, 0.46 (95 % CI: 0.21–1.01) for youth in the Healthy BMI and lifestyle class, and 0.68 (95 % CI: 0.42–1.10) for youth in the Average BMI and lifestyle class.</div></div><div><h3>Conclusions</h3><div>The latent class analysis revealed four youth subgroups with different lifestyle, health, and sociodemographic characteristics, and youth prediabetes/diabetes status was associated with the latent class membership. The results suggest potential heterogeneous interventions over one-size-fits-all approaches to mitigate prediabetes/diabetes risk among youth.</div></div>","PeriodicalId":20339,"journal":{"name":"Preventive medicine","volume":"199 ","pages":"Article 108384"},"PeriodicalIF":3.2,"publicationDate":"2025-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144812228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0