Preventive medicine最新文献

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Contingency management in the treatment of substance use disorders: A historical narrative. 药物使用障碍治疗中的应急管理:历史叙述。
IF 3.2 2区 医学
Preventive medicine Pub Date : 2026-05-01 DOI: 10.1016/j.ypmed.2026.108590
Maxine Stitzer
{"title":"Contingency management in the treatment of substance use disorders: A historical narrative.","authors":"Maxine Stitzer","doi":"10.1016/j.ypmed.2026.108590","DOIUrl":"10.1016/j.ypmed.2026.108590","url":null,"abstract":"<p><p>This narrative provides an overview of contingency management (CM) in the treatment of substance use disorders (SUDs) from inception to present day. Highlights and examples are selected by a founder in the field and follow her research lineage. Positive reinforcement interventions that could counter the powerful reinforcing effects of abused drugs and promote abstinence were introduced in demonstration studies during the 1960's and 70's at Johns Hopkins. Subsequent innovators developed formal treatment interventions using monetary-based vouchers (Higgins) and prize draws (Petry) as rewards for objective evidence of recent drug abstinence. CM research subsequently flourished using these delivery models, demonstrating efficacy and generality across populations. Recently, with advent of remote drug/alcohol testing, CM treatments have been adapted for digital delivery via phone apps. This development along with advocacy for use of evidence-based treatments, may further boost clinical adoption. It is notable that a treatment model, grounded in behavioral psychology concepts and incorporating the most rigorous behavioral principles, has proven to be sufficiently efficacious to support a robust research and policy enterprise for over 50 years.</p>","PeriodicalId":20339,"journal":{"name":"Preventive medicine","volume":" ","pages":"108590"},"PeriodicalIF":3.2,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147819741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Awareness and use of pre-exposure prophylaxis and awareness of treatment-as-prevention among adults in the United States: National estimates and associations with exposure to the Let's Stop HIV Together campaign, 2022–2024 美国成年人接触前预防的认识和使用以及治疗即预防的认识:2022-2024年全国估计和与接触“让我们一起阻止艾滋病毒”运动的联系
IF 3.2 2区 医学
Preventive medicine Pub Date : 2026-05-01 Epub Date: 2026-02-11 DOI: 10.1016/j.ypmed.2026.108532
Ryan S. Paquin , Vanessa Boudewyns , Hannah Getachew-Smith , Jo Ellen Stryker , Jennifer D. Uhrig
{"title":"Awareness and use of pre-exposure prophylaxis and awareness of treatment-as-prevention among adults in the United States: National estimates and associations with exposure to the Let's Stop HIV Together campaign, 2022–2024","authors":"Ryan S. Paquin ,&nbsp;Vanessa Boudewyns ,&nbsp;Hannah Getachew-Smith ,&nbsp;Jo Ellen Stryker ,&nbsp;Jennifer D. Uhrig","doi":"10.1016/j.ypmed.2026.108532","DOIUrl":"10.1016/j.ypmed.2026.108532","url":null,"abstract":"<div><h3>Objective</h3><div>Benchmarks for public awareness of pre-exposure prophylaxis (PrEP) and human immunodeficiency virus (HIV) Treatment-as-Prevention (TasP) are sparse, and evidence about whether public health communication campaigns are associated with awareness and use is lacking. This study assessed whether exposure to the Centers for Disease Control and Prevention's (CDC) <em>Let's Stop HIV Together</em> campaign was associated with self-reported PrEP and TasP awareness and PrEP use.</div></div><div><h3>Methods</h3><div>Data were drawn from the 2022–2024 SpringStyles, a probability-based online survey of adults in the United States. Weighted logistic regression models assessed PrEP awareness, TasP awareness, and PrEP use by sociodemographic characteristics, prior HIV testing, and campaign exposure.</div></div><div><h3>Results</h3><div>Awareness of PrEP and TasP increased from 2022 to 2024, reaching 38.0% and 39.0%, respectively. Respondents who recalled the CDC's campaign were significantly more likely to be aware of PrEP (52.9% vs 34.1%) and TasP (55.9% vs 35.8%), and to report PrEP use (1.9% vs. 1.0%).</div></div><div><h3>Conclusions</h3><div>These nationally representative, repeated cross-sectional estimates reveal gains in PrEP and TasP awareness over time. The association of campaign exposure with PrEP and TasP awareness and PrEP use underscores the importance of federally funded health communication initiatives to end the HIV epidemic in the United States.</div></div>","PeriodicalId":20339,"journal":{"name":"Preventive medicine","volume":"206 ","pages":"Article 108532"},"PeriodicalIF":3.2,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146161851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Injunctive substance use norms among substance-naïve youth in the United States: Differences by sexual identity and sex assigned at birth 美国substance-naïve青少年的禁止性物质使用规范:性别认同和出生时性别分配的差异
IF 3.2 2区 医学
Preventive medicine Pub Date : 2026-05-01 Epub Date: 2026-02-11 DOI: 10.1016/j.ypmed.2026.108531
Evan A. Krueger, Audrey Hang Hai
{"title":"Injunctive substance use norms among substance-naïve youth in the United States: Differences by sexual identity and sex assigned at birth","authors":"Evan A. Krueger,&nbsp;Audrey Hang Hai","doi":"10.1016/j.ypmed.2026.108531","DOIUrl":"10.1016/j.ypmed.2026.108531","url":null,"abstract":"<div><h3>Background</h3><div>Sexual minority (SM) youth are more likely than heterosexual youth to engage in substance use. Injunctive norms, or perceptions of others' substance use attitudes, contribute to youth substance use initiation and progression.</div></div><div><h3>Methods</h3><div>Among substance-naïve youth (ages 12–17; <em>N</em> = 7628) in the 2023 National Survey on Drug Use and Health, we examined differences in perceived parental, close friend, and personal disapproval of cigarette smoking, marijuana experimentation, monthly marijuana use, and near-daily alcohol use across five sexual identity groups (heterosexual, gay, bisexual, different term, unsure) and sex assigned at birth.</div></div><div><h3>Results</h3><div>Across groups and substances, youth perceived the highest substance use disapproval from parents (range = 72.4% – 97.4%), followed by personal disapproval (range = 52.1% - 87.7%) and disapproval by close friends (range = 48.6% - 81.6%). In multivariable models, bisexual, different term, and unsure youth reported lower close friend (IRR range = 0.89–0.97) and personal (IRR range = 0.89–0.92) disapproval, compared to heterosexual youth. SM females reported lower close friend and personal disapproval than heterosexual females.</div></div><div><h3>Conclusions</h3><div>SM youth perceive more permissive norms towards substance use. Prevention strategies addressing peer norms and personal permissiveness may be critical for addressing SM youth substance use inequities.</div></div>","PeriodicalId":20339,"journal":{"name":"Preventive medicine","volume":"206 ","pages":"Article 108531"},"PeriodicalIF":3.2,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146161852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The epidemiology of physical activity guideline adherence among 35,633 adults: Findings from the South Australian Population Health Survey. 35,633名成年人遵守体育活动指南的流行病学研究:来自南澳大利亚人口健康调查的结果
IF 3.2 2区 医学
Preventive medicine Pub Date : 2026-04-27 DOI: 10.1016/j.ypmed.2026.108587
Jason A Bennie, Kamalesh Venugopal, Sophie Burnell, Ben Krumeich, Ely Taylor, Carol Maher, Alanna Sincovich, Rebecca Nolan
{"title":"The epidemiology of physical activity guideline adherence among 35,633 adults: Findings from the South Australian Population Health Survey.","authors":"Jason A Bennie, Kamalesh Venugopal, Sophie Burnell, Ben Krumeich, Ely Taylor, Carol Maher, Alanna Sincovich, Rebecca Nolan","doi":"10.1016/j.ypmed.2026.108587","DOIUrl":"10.1016/j.ypmed.2026.108587","url":null,"abstract":"<p><strong>Objective: </strong>Since 2010, global physical activity guidelines have recommended that adults engage in moderate-to-vigorous physical activity (MVPA) and muscle-strengthening exercise (MSE). However, health surveillance rarely assesses both. This study describes the prevalence and correlates of adherence to the joint MVPA-MSE guideline in a large sample of Australian adults.</p><p><strong>Method: </strong>Data were drawn from pooling seven waves of the South Australian Population Health Survey (2018 to 2024). Weighted proportions meeting both guidelines (MVPA ≥150 min/week/MSE ≥2 times/week) were calculated. Poisson regression estimated prevalence ratios for meeting both guidelines across sociodemographic/lifestyle factors and for nine chronic conditions by guideline adherence (met neither; MVPA only; MSE only; met both), adjusted for confounders (e.g., age, smoking, body mass index).</p><p><strong>Results: </strong>Among 35,633 adults (18-64 years), 25.1% (95% CI: 24.7, 25.6%) met both MVPA-MSE guidelines. In a multivariate analysis, older adults, women, people from socioeconomically disadvantaged areas, and those living with obesity had lower prevalence ratios for meeting both guidelines. Meeting both guidelines was associated with the lowest prevalence ratios for anxiety, cardiovascular disease, depression, diabetes, high cholesterol and hypertension.</p><p><strong>Conclusion: </strong>Low prevalence of meeting guidelines and associations with chronic conditions highlight the need for strategies that promote physical activity by addressing both inequalities in access and wider social, environmental, and structural determinants.</p>","PeriodicalId":20339,"journal":{"name":"Preventive medicine","volume":" ","pages":"108587"},"PeriodicalIF":3.2,"publicationDate":"2026-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147779228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Longitudinal investigation of the association between alcohol use and subsequent e-cigarette use among young adults in the United States. 美国年轻人酒精使用与随后电子烟使用之间关系的纵向调查。
IF 3.2 2区 医学
Preventive medicine Pub Date : 2026-04-26 DOI: 10.1016/j.ypmed.2026.108588
Siobhan N Perks, Melissa A Clark, Suzanne M Colby, Jennifer E Merrill
{"title":"Longitudinal investigation of the association between alcohol use and subsequent e-cigarette use among young adults in the United States.","authors":"Siobhan N Perks, Melissa A Clark, Suzanne M Colby, Jennifer E Merrill","doi":"10.1016/j.ypmed.2026.108588","DOIUrl":"10.1016/j.ypmed.2026.108588","url":null,"abstract":"<p><strong>Objective: </strong>Few studies have considered whether alcohol use is associated with subsequent e-cigarette initiation and/or use. This study examined prospective associations between three past 30-day measures of alcohol use (any use, frequency, quantity) and two e-cigarette-related outcomes (initiation, current use).</p><p><strong>Methods: </strong>The sample included 3453 tobacco-naïve young adults aged 18-24 who completed Waves 6-7 (data collected 2021-2023 in the United States) of the nationally representative Population Assessment of Tobacco and Health Study. Multivariable logistic regression models examined associations between Wave 6 alcohol use and Wave 7 e-cigarette use, controlling for sociodemographic covariates.</p><p><strong>Results: </strong>A total of 229 participants (5.9%) reported e-cigarette initiation at Wave 7, of which 148 (66.0%) reported current use. Wave 6 past 30-day alcohol use (versus none) and quantity, but not frequency, were significantly associated with Wave 7 e-cigarette initiation. None of the alcohol-related variables were significantly associated with current e-cigarette use at follow-up.</p><p><strong>Conclusions: </strong>Young adults who reported past 30-day alcohol use and those who typically consumed more drinks per occasion were more likely to initiate e-cigarette use. E-cigarette-related prevention efforts should include targeted messaging for young adults who drink, and alcohol-related interventions should highlight e-cigarette uptake as a potential consequence of alcohol consumption.</p>","PeriodicalId":20339,"journal":{"name":"Preventive medicine","volume":" ","pages":"108588"},"PeriodicalIF":3.2,"publicationDate":"2026-04-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147779117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Corrigendum to "Child access prevention laws and firearm storage in the US: Associations by law stringency and social vulnerability" Preventive Medicine Volume 204 (2026), 108516. 预防医学第204卷(2026),108516,《美国儿童接触预防法律和枪支储存:法律严格性和社会脆弱性协会》的勘误表。
IF 3.2 2区 医学
Preventive medicine Pub Date : 2026-04-21 DOI: 10.1016/j.ypmed.2026.108579
Stephen N Oliphant, Michelle Degli Esposti, Katherine G Hastings, Heather A Hartman, Peter F Ehrlich, Patrick M Carter, Rebeccah L Sokol
{"title":"Corrigendum to \"Child access prevention laws and firearm storage in the US: Associations by law stringency and social vulnerability\" Preventive Medicine Volume 204 (2026), 108516.","authors":"Stephen N Oliphant, Michelle Degli Esposti, Katherine G Hastings, Heather A Hartman, Peter F Ehrlich, Patrick M Carter, Rebeccah L Sokol","doi":"10.1016/j.ypmed.2026.108579","DOIUrl":"https://doi.org/10.1016/j.ypmed.2026.108579","url":null,"abstract":"","PeriodicalId":20339,"journal":{"name":"Preventive medicine","volume":" ","pages":"108579"},"PeriodicalIF":3.2,"publicationDate":"2026-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147779015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A recommendation to include support for perinatal smoking-cessation treatment in the SAMHSA advisory on contingency management. 建议将支持围产期戒烟治疗纳入SAMHSA应急管理咨询。
IF 3.2 2区 医学
Preventive medicine Pub Date : 2026-04-16 DOI: 10.1016/j.ypmed.2026.108580
Stephen T Higgins
{"title":"A recommendation to include support for perinatal smoking-cessation treatment in the SAMHSA advisory on contingency management.","authors":"Stephen T Higgins","doi":"10.1016/j.ypmed.2026.108580","DOIUrl":"10.1016/j.ypmed.2026.108580","url":null,"abstract":"<p><p>This Commentary offers a brief, evidence-based recommendation that perinatal smoking cessation be included among the list of substance use disorders that the U.S. Substance Abuse and Mental Health Services Administration (SAMHSA) has approved for use of federal funds to support Contingency Management (CM) treatment. Perinatal smoking is a serious U.S. public health problem that adversely impacts the health of mothers and exposed infants, and for which more effective and accessible treatments are sorely needed. CM treatment wherein patients receive material incentives contingent on abstaining from drug use or meeting other treatment goals is a highly effective treatment for a broad range of substance use disorders including smoking cessation. Evidence from randomized clinical trials and meta-analyses investigating CM's efficacy for perinatal smoking cessation are briefly summarized. The evidence provides robust empirical support for CM's efficacy for improving perinatal smoking-cessation rates. With SAMHSA's support and broad implementation, CM has the potential to meet the need for more effective and accessible perinatal smoking-cessation treatment in the U.S.</p>","PeriodicalId":20339,"journal":{"name":"Preventive medicine","volume":" ","pages":"108580"},"PeriodicalIF":3.2,"publicationDate":"2026-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147717499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinic-based SNAP enrollment as a strategy to strengthen food security 以诊所为基础的SNAP注册作为加强粮食安全的战略。
IF 3.2 2区 医学
Preventive medicine Pub Date : 2026-04-01 Epub Date: 2026-01-29 DOI: 10.1016/j.ypmed.2026.108519
Matthew C. Guido , Madeline P. Maier , Alister F. Martin
{"title":"Clinic-based SNAP enrollment as a strategy to strengthen food security","authors":"Matthew C. Guido ,&nbsp;Madeline P. Maier ,&nbsp;Alister F. Martin","doi":"10.1016/j.ypmed.2026.108519","DOIUrl":"10.1016/j.ypmed.2026.108519","url":null,"abstract":"","PeriodicalId":20339,"journal":{"name":"Preventive medicine","volume":"205 ","pages":"Article 108519"},"PeriodicalIF":3.2,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146096877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The impact of frequent interruptions to sedentary behavior on postprandial metabolism in healthy adults: A systematic review and meta-analysis of randomized controlled trials 频繁中断久坐行为对健康成人餐后代谢的影响:随机对照试验的系统回顾和荟萃分析
IF 3.2 2区 医学
Preventive medicine Pub Date : 2026-03-01 Epub Date: 2026-01-23 DOI: 10.1016/j.ypmed.2026.108517
Yuli Zhang , Zhenghui Zha , Cuiyun Tian , Dongxiang Huang , Tuming Shen , Jingbin Liu , Songtao Wang
{"title":"The impact of frequent interruptions to sedentary behavior on postprandial metabolism in healthy adults: A systematic review and meta-analysis of randomized controlled trials","authors":"Yuli Zhang ,&nbsp;Zhenghui Zha ,&nbsp;Cuiyun Tian ,&nbsp;Dongxiang Huang ,&nbsp;Tuming Shen ,&nbsp;Jingbin Liu ,&nbsp;Songtao Wang","doi":"10.1016/j.ypmed.2026.108517","DOIUrl":"10.1016/j.ypmed.2026.108517","url":null,"abstract":"<div><h3>Objectives</h3><div>To evaluate the effects of interrupting sedentary behavior on postprandial metabolic outcomes in healthy adults.</div></div><div><h3>Methods</h3><div>We systematically searched seven databases (PubMed, Embase, Scopus, Cochrane, Web of Science, SPORTDiscus, and CINAHL Complete) from inception to June 6, 2025, for eligible randomized controlled trials. Primary outcomes included total and incremental areas under the curve for glucose, insulin, and triglycerides. Study quality (Cochrane Risk of Bias version 2) and overall evidence quality (Grading of Recommendations, Assessment, Development, and Evaluations) were assessed. Data were pooled using random-effects meta-analysis in Stata 18.0, with effects expressed as standardized mean difference (SMD) and 95% confidence interval (95% CI).</div></div><div><h3>Results</h3><div>Seventeen randomized controlled trials comprising 337 healthy adults were included. Meta-analysis showed that interrupting sedentary behavior significantly reduced glucose incremental area under the curve (SMD = −0.35; 95% CI: −0.56, −0.15) and insulin incremental area under the curve (SMD = −0.37; 95% CI: −0.56, −0.18), but had no significant effect on total area under the curve for glucose, insulin, and triglycerides, nor on the incremental area for triglycerides.</div></div><div><h3>Conclusions</h3><div>Interrupting sedentary behavior improves postprandial metabolism by specifically reducing the spike in blood glucose and insulin after a meal, without affecting overall metabolic exposure or lipid levels.</div></div>","PeriodicalId":20339,"journal":{"name":"Preventive medicine","volume":"204 ","pages":"Article 108517"},"PeriodicalIF":3.2,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146046388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The dual risk profile of site-specific cancers in vitiligo: A systematic review and meta-analysis 白癜风部位特异性癌症的双重风险概况:系统回顾和荟萃分析
IF 3.2 2区 医学
Preventive medicine Pub Date : 2026-03-01 Epub Date: 2026-01-07 DOI: 10.1016/j.ypmed.2026.108504
Yanbin Chen , Yongyi Xie , Nanhui Wu , Ruoqi Wang , Suwei Tang , Mingyuan Xu , Xin Ma , Yeqiang Liu
{"title":"The dual risk profile of site-specific cancers in vitiligo: A systematic review and meta-analysis","authors":"Yanbin Chen ,&nbsp;Yongyi Xie ,&nbsp;Nanhui Wu ,&nbsp;Ruoqi Wang ,&nbsp;Suwei Tang ,&nbsp;Mingyuan Xu ,&nbsp;Xin Ma ,&nbsp;Yeqiang Liu","doi":"10.1016/j.ypmed.2026.108504","DOIUrl":"10.1016/j.ypmed.2026.108504","url":null,"abstract":"<div><h3>Objectives</h3><div>Site-specific cancer risks in vitiligo patients remain inconsistent, with paradoxical evidence for individual malignancies and no synthesis.</div></div><div><h3>Methods</h3><div>Systematic searches in PubMed (1996–February 2025), Embase (1947–February 2025), Web of Science (1997–February 2025), Cochrane Library (1996–February 2025) (pre-inception retroactively indexed studies, January 1900–February 2025); 13 included in our meta-analysis. Stata 18.0 computed pooled RRs (95% CIs); heterogeneity assessed via publication bias, subgroup and sensitivity analyses.</div></div><div><h3>Results</h3><div>The study incorporated thirteen studies. It is evident that there is a statistically significant correlation between the occurrence of vitiligo and an elevated risk of developing thyroid cancer (RR = 1.59, 95% CI [1.19, 2.12]). Conversely, a significant reduction in risk was observed for overall cancer (RR = 0.77, 95% CI [0.66, 0.90]), cancers of the respiratory system (RR = 0.75, 95% CI [0.66, 0.84]), digestive system (RR = 0.74, 95% CI [0.63, 0.87]), and skin cancers (RR = 0.58, 95% CI [0.36, 0.93]).</div></div><div><h3>Conclusions</h3><div>This study demonstrates a dual cancer risk profile in vitiligo: increased risk for thyroid cancer, but decreased risk for overall cancer, internal malignancies (respiratory and digestive systems) and skin cancers. These findings suggest the potential need for customized cancer surveillance strategies and investigation into preventive interventions.</div></div>","PeriodicalId":20339,"journal":{"name":"Preventive medicine","volume":"204 ","pages":"Article 108504"},"PeriodicalIF":3.2,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145929071","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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