Placenta最新文献

{"title":"Intracellular Placental Iron Transport as a Regulator of Neurodevelopmental Programming","authors":"Timothée Furrer, Ines Reynoso, Jürg Gertsch, Mariana Schröder, Christiane Albrecht","doi":"10.1016/j.placenta.2026.08.004","DOIUrl":"10.1016/j.placenta.2026.08.004","url":null,"abstract":"","PeriodicalId":20203,"journal":{"name":"Placenta","volume":"183 ","pages":"Page e188"},"PeriodicalIF":3.1,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149199404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Maternal-fetal interface-associated macrophage states shape the microenvironment in the human decidua basalis","authors":"Barbara Öhler, Anna-Lena Höbler, Andreas Ian Lackner, Peter Haslinger, Gudrun Meinhardt, Theresa Maxian, Jasmin Wächter, Anna-Maria Prandstetter, Hanna Waldhäusl, Leila Saleh, Martin Knöfler, Sandra Haider, Michael Angelo, Jürgen Pollheimer","doi":"10.1016/j.placenta.2026.08.015","DOIUrl":"10.1016/j.placenta.2026.08.015","url":null,"abstract":"","PeriodicalId":20203,"journal":{"name":"Placenta","volume":"183 ","pages":"Page e191"},"PeriodicalIF":3.1,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149199380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The physiological role of soluble fms-like tyrosine kinase-1 (sFlt-1) in placenta during normal pregnancy.","authors":"Mari Tabuse, Hitomi Nakamura, Taiga Yamaguchi, Yoshitomo Tanaka, Kazuya Mimura, Masayuki Endo, Hirokazu Kaji, Keiichi Kumasawa, Michiko Kodama","doi":"10.1016/j.placenta.2026.08.043","DOIUrl":"10.1016/j.placenta.2026.08.043","url":null,"abstract":"","PeriodicalId":20203,"journal":{"name":"Placenta","volume":"183 ","pages":"Page e199"},"PeriodicalIF":3.1,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149199498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigating the Impact of Zika Virus Infection on Trophoblast Differentiation and its Potential Role in Adverse Pregnancy Outcomes","authors":"Chak Sum Wong, Cheuk-Lun, Keith LEE, Wang Ngai, Franklin CHOW","doi":"10.1016/j.placenta.2026.08.065","DOIUrl":"10.1016/j.placenta.2026.08.065","url":null,"abstract":"","PeriodicalId":20203,"journal":{"name":"Placenta","volume":"183 ","pages":"Page e206"},"PeriodicalIF":3.1,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149199512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of an adverse preconception environment on placental programming in a MEM mouse (DOHaD model mouse)","authors":"Keisuke Nakajima, Takeshi Nagamatsu, Mari Ichinose, Masatake Toshimitsu, Seisuke Sayama, Keiichi Kumasawa, Takayuki Iriyama, Miyuki Harada, Yasushi Hirota","doi":"10.1016/j.placenta.2026.08.020","DOIUrl":"10.1016/j.placenta.2026.08.020","url":null,"abstract":"","PeriodicalId":20203,"journal":{"name":"Placenta","volume":"183 ","pages":"Page e192"},"PeriodicalIF":3.1,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149199282","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fetal sex and inflammatory responses in preterm prelabor rupture of membranes","authors":"Lucie Dolezelova,&nbsp;Ivana Musilova,&nbsp;Jana Matulova,&nbsp;Helena Hornychova,&nbsp;Radka Bolehovska,&nbsp;Rudolf Kukla,&nbsp;Jarmila Trumpesova,&nbsp;Marek Lubusky,&nbsp;Stepanka Bubenikova,&nbsp;Bo Jacobsson,&nbsp;Marian Kacerovsky","doi":"10.1016/j.placenta.2026.09.002","DOIUrl":"10.1016/j.placenta.2026.09.002","url":null,"abstract":"<div><h3>Background</h3><div>Fetal sex influences placental development and immune regulation. Although sex-related differences in placental vascular pathology have been described, their influence on intra-amniotic inflammation and placental inflammatory responses in pregnancies complicated by preterm prelabor rupture of membranes (PPROM) remains poorly understood.</div></div><div><h3>Objective</h3><div>To determine whether fetal sex is associated with differences in the intensity of the intra-amniotic inflammatory response, the distribution of intra-amniotic categories defined according to the presence or absence of microbial invasion of the amniotic cavity and intra-amniotic inflammation, acute placental inflammatory lesions, and short-term neonatal outcomes in PPROM.</div></div><div><h3>Study design</h3><div>This retrospective cohort study included 852 singleton pregnancies complicated by PPROM between 23 + 0 and 36 + 6 weeks of gestation that underwent transabdominal amniocentesis. Pregnancies complicated by maternal hypertensive disorders or diabetes mellitus were excluded from the analysis. The intra-amniotic inflammatory response was assessed by amniotic fluid interleukin-6 levels. Placental inflammatory lesions were evaluated according to the histopathological criteria described by Salafia et al.</div></div><div><h3>Results</h3><div>The distribution of intra-amniotic categories (<em>P</em> = 0.28) and amniotic fluid interleukin-6 levels did not differ between pregnancies carrying female and male fetuses. The prevalence of most acute placental inflammatory lesions was comparable between the groups. However, pregnancies carrying female fetuses had a higher prevalence of early-stage funisitis (11% vs. 5%; <em>P</em> = 0.002). Female newborns also had a higher prevalence of bronchopulmonary dysplasia (7% vs. 3%; <em>P</em> = 0.002).</div></div><div><h3>Conclusion</h3><div>In PPROM, fetal sex was not associated with differences in the intra-amniotic environment. However, female fetuses exhibited a higher prevalence of early-stage funisitis, suggesting that fetal sex may modulate the earliest histopathological manifestation of the fetal inflammatory response despite comparable intra-amniotic inflammatory exposure.</div></div>","PeriodicalId":20203,"journal":{"name":"Placenta","volume":"183 ","pages":"Pages 136-143"},"PeriodicalIF":3.1,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148963587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"THE EXTRACELLULAR MATRIX Altered THE PHENOTYPIC EXPRESSION of ENDOMETRIAL MESENCHYMAL STROMAL/STEM CELLS IN VITRO","authors":"Mingna Sun,&nbsp;Ernest H.Y. Ng,&nbsp;William S.B. Yeung,&nbsp;Philip C.N. Chiu,&nbsp;Rachel Chan","doi":"10.1016/j.placenta.2026.08.077","DOIUrl":"10.1016/j.placenta.2026.08.077","url":null,"abstract":"","PeriodicalId":20203,"journal":{"name":"Placenta","volume":"183 ","pages":"Page e210"},"PeriodicalIF":3.1,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149199193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Single-cell transcriptomics of term trophoblast stem cells reveals an extravillous trophoblast precursor phenotype","authors":"Sampada Kallol,&nbsp;Robert Morey,&nbsp;Jaroslav Slamecka,&nbsp;Seher Basi,&nbsp;Ryuta Miyake,&nbsp;Morgan Meads,&nbsp;Megan Mulholland,&nbsp;Mariko Horii,&nbsp;Francesca Soncin,&nbsp;Mana M. Parast","doi":"10.1016/j.placenta.2026.08.080","DOIUrl":"10.1016/j.placenta.2026.08.080","url":null,"abstract":"","PeriodicalId":20203,"journal":{"name":"Placenta","volume":"183 ","pages":"Page e211"},"PeriodicalIF":3.1,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149199194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Single-Cell and Pathway-Level Dissection of Immune Dysregulation in Recurrent Pregnancy Loss","authors":"Priyanka Srivastava,&nbsp;Ravi Pratap Singh Bhadoriya,&nbsp;Chitra Bhardwaj,&nbsp;Minakshi Rohilla,&nbsp;Anupriya Kaur,&nbsp;Inusha Panigrahi,&nbsp;Seema Chopra","doi":"10.1016/j.placenta.2026.08.048","DOIUrl":"10.1016/j.placenta.2026.08.048","url":null,"abstract":"","PeriodicalId":20203,"journal":{"name":"Placenta","volume":"183 ","pages":"Page e201"},"PeriodicalIF":3.1,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149199547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Signals from the Decidua: Ligand-Mediated Control of Cell Column Formation and EVT Differentiation in Early Human Placenta","authors":"Gudrun Meinhardt,&nbsp;Jasmin Wächter,&nbsp;Hanna Waldhäusl,&nbsp;Sara Rebekka Lugmayr,&nbsp;Theresa Maxian,&nbsp;Anna-Maria Prandstetter,&nbsp;Jürgen Pollheimer,&nbsp;Sandra Haider,&nbsp;Martin Knöfler","doi":"10.1016/j.placenta.2026.08.061","DOIUrl":"10.1016/j.placenta.2026.08.061","url":null,"abstract":"","PeriodicalId":20203,"journal":{"name":"Placenta","volume":"183 ","pages":"Page e205"},"PeriodicalIF":3.1,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149199628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}