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Forward and reverse cardio-oncology 正向和反向心脏肿瘤学
IF 33.6 1区 医学
Physiological reviews Pub Date : 2025-09-23 DOI: 10.1152/physrev.00041.2024
Wouter C. Meijers, Joseph Pierre Aboumsallem, Alexander R. Lyon, Javid Moslehi, Rudolf A. de Boer
{"title":"Forward and reverse cardio-oncology","authors":"Wouter C. Meijers, Joseph Pierre Aboumsallem, Alexander R. Lyon, Javid Moslehi, Rudolf A. de Boer","doi":"10.1152/physrev.00041.2024","DOIUrl":"https://doi.org/10.1152/physrev.00041.2024","url":null,"abstract":"Physiological Reviews, Ahead of Print. <br/>","PeriodicalId":20193,"journal":{"name":"Physiological reviews","volume":"40 1","pages":""},"PeriodicalIF":33.6,"publicationDate":"2025-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145116159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Immunological and regenerative properties of lung stem cells 肺干细胞的免疫和再生特性
IF 33.6 1区 医学
Physiological reviews Pub Date : 2025-09-12 DOI: 10.1152/physrev.00056.2024
De Hao, Yimeng Liu, Li Li, Barry R. Stripp, Huaiyong Chen
{"title":"Immunological and regenerative properties of lung stem cells","authors":"De Hao, Yimeng Liu, Li Li, Barry R. Stripp, Huaiyong Chen","doi":"10.1152/physrev.00056.2024","DOIUrl":"https://doi.org/10.1152/physrev.00056.2024","url":null,"abstract":"Physiological Reviews, Ahead of Print. <br/>","PeriodicalId":20193,"journal":{"name":"Physiological reviews","volume":"11 1","pages":""},"PeriodicalIF":33.6,"publicationDate":"2025-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145043420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Evolving Pathophysiology of Bronchopulmonary Dysplasia 支气管肺发育不良的病理生理学演变
IF 33.6 1区 医学
Physiological reviews Pub Date : 2025-08-29 DOI: 10.1152/physrev.00042.2024
Namasivayam Ambalavanan, Gail Deutsch, Gloria Pryhuber, Colm P. Travers, Kent A. Willis
{"title":"The Evolving Pathophysiology of Bronchopulmonary Dysplasia","authors":"Namasivayam Ambalavanan, Gail Deutsch, Gloria Pryhuber, Colm P. Travers, Kent A. Willis","doi":"10.1152/physrev.00042.2024","DOIUrl":"https://doi.org/10.1152/physrev.00042.2024","url":null,"abstract":"Physiological Reviews, Ahead of Print. <br/>","PeriodicalId":20193,"journal":{"name":"Physiological reviews","volume":"57 1","pages":""},"PeriodicalIF":33.6,"publicationDate":"2025-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144919242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Acid-sensing ion channels: structure, function, pharmacology and clinical significance 酸感离子通道：结构、功能、药理及临床意义
IF 33.6 1区 医学
Physiological reviews Pub Date : 2025-08-28 DOI: 10.1152/physrev.00002.2025
Lachlan D. Rash, Stephan Kellenberger
{"title":"Acid-sensing ion channels: structure, function, pharmacology and clinical significance","authors":"Lachlan D. Rash, Stephan Kellenberger","doi":"10.1152/physrev.00002.2025","DOIUrl":"https://doi.org/10.1152/physrev.00002.2025","url":null,"abstract":"Physiological Reviews, Ahead of Print. <br/>","PeriodicalId":20193,"journal":{"name":"Physiological reviews","volume":"57 1","pages":""},"PeriodicalIF":33.6,"publicationDate":"2025-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144916226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Neurite outgrowth inhibitor-B (Nogo-B) in physiology and disease. 神经突生长抑制剂- b （Nogo-B）在生理和疾病中的作用。
IF 33.6 1区 医学
Physiological reviews Pub Date : 2025-08-28 DOI: 10.1152/physrev.00052.2024
Wei R Tan, David A Long, Luigi Gnudi
{"title":"Neurite outgrowth inhibitor-B (Nogo-B) in physiology and disease.","authors":"Wei R Tan, David A Long, Luigi Gnudi","doi":"10.1152/physrev.00052.2024","DOIUrl":"https://doi.org/10.1152/physrev.00052.2024","url":null,"abstract":"Physiological Reviews, Ahead of Print. <br/>","PeriodicalId":20193,"journal":{"name":"Physiological reviews","volume":"53 1","pages":""},"PeriodicalIF":33.6,"publicationDate":"2025-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144916225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sleep‘s contribution to memory formation 睡眠对记忆形成的贡献
IF 33.6 1区 医学
Physiological reviews Pub Date : 2025-08-28 DOI: 10.1152/physrev.00054.2024
Nicolas D. Lutz, Maximilian Harkotte, Jan Born
{"title":"Sleep‘s contribution to memory formation","authors":"Nicolas D. Lutz, Maximilian Harkotte, Jan Born","doi":"10.1152/physrev.00054.2024","DOIUrl":"https://doi.org/10.1152/physrev.00054.2024","url":null,"abstract":"Physiological Reviews, Ahead of Print. <br/>","PeriodicalId":20193,"journal":{"name":"Physiological reviews","volume":"29 1","pages":""},"PeriodicalIF":33.6,"publicationDate":"2025-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144916224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sex, hormones, and lung health 性，荷尔蒙和肺部健康
IF 33.6 1区 医学
Physiological reviews Pub Date : 2025-08-06 DOI: 10.1152/physrev.00026.2024
Patricia Silveyra, Maksat Babayev, Carolyn Damilola Ekpruke
{"title":"Sex, hormones, and lung health","authors":"Patricia Silveyra, Maksat Babayev, Carolyn Damilola Ekpruke","doi":"10.1152/physrev.00026.2024","DOIUrl":"https://doi.org/10.1152/physrev.00026.2024","url":null,"abstract":"Physiological Reviews, Ahead of Print. <br/>","PeriodicalId":20193,"journal":{"name":"Physiological reviews","volume":"16 1","pages":""},"PeriodicalIF":33.6,"publicationDate":"2025-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144787516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Proglucagon-derived Peptides: Human Physiology and Therapeutic Potential 胰高血糖素衍生肽：人体生理学和治疗潜力
IF 33.6 1区 医学
Physiological reviews Pub Date : 2025-07-28 DOI: 10.1152/physrev.00057.2024
Lærke S. Gasbjerg, Casper K. Nielsen, Malte P. Suppli, Magnus F. G. Grøendahl, Jens J. Holst, Filip K. Knop, Palle B. Jeppesen, Asger B. Lund
{"title":"Proglucagon-derived Peptides: Human Physiology and Therapeutic Potential","authors":"Lærke S. Gasbjerg, Casper K. Nielsen, Malte P. Suppli, Magnus F. G. Grøendahl, Jens J. Holst, Filip K. Knop, Palle B. Jeppesen, Asger B. Lund","doi":"10.1152/physrev.00057.2024","DOIUrl":"https://doi.org/10.1152/physrev.00057.2024","url":null,"abstract":"Physiological Reviews, Ahead of Print. <br/>","PeriodicalId":20193,"journal":{"name":"Physiological reviews","volume":"26 1","pages":""},"PeriodicalIF":33.6,"publicationDate":"2025-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144720202","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Metabolic adaptations in cancer progression 癌症进展中的代谢适应
IF 33.6 1区 医学
Physiological reviews Pub Date : 2025-07-28 DOI: 10.1152/physrev.00037.2024
Yiming Peng-Winkler, Sarah-Maria Fendt
{"title":"Metabolic adaptations in cancer progression","authors":"Yiming Peng-Winkler, Sarah-Maria Fendt","doi":"10.1152/physrev.00037.2024","DOIUrl":"https://doi.org/10.1152/physrev.00037.2024","url":null,"abstract":"Physiological Reviews, Ahead of Print. <br/>","PeriodicalId":20193,"journal":{"name":"Physiological reviews","volume":"5 1","pages":""},"PeriodicalIF":33.6,"publicationDate":"2025-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144720200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Angiocrine and Pericrine Signaling: How Endothelial Cells and Pericytes Drive Cancer Progression and Therapy Resistance. 血管分泌和周分泌信号传导：内皮细胞和周细胞如何驱动癌症进展和治疗耐药性。
IF 33.6 1区 医学
Physiological reviews Pub Date : 2025-07-23 DOI: 10.1152/physrev.00046.2024
Alexander M Jordan,Rebecca J G Drake,Kairbaan M Hodivala-Dilke
{"title":"Angiocrine and Pericrine Signaling: How Endothelial Cells and Pericytes Drive Cancer Progression and Therapy Resistance.","authors":"Alexander M Jordan,Rebecca J G Drake,Kairbaan M Hodivala-Dilke","doi":"10.1152/physrev.00046.2024","DOIUrl":"https://doi.org/10.1152/physrev.00046.2024","url":null,"abstract":"The emergence of treatment resistance and metastasis are significant challenges that need to be addressed to improve cancer patient outcomes. Greater insight into the mechanisms regulating these processes is needed to identify novel targets for the development of effective treatments. The importance of blood vessel interactions, including endothelial angiocrine and pericyte pericrine signals, with surrounding tissues, has been well established in regulating several normal physiological functions, including angiogenesis, metabolism, wound healing and development. They have also been implicated in the mechanisms of cancer growth, metastatic dissemination, regulation of the immune microenvironment and therapeutic resistance. This review provides an overview of the angiocrine and pericrine processes that regulate cancer, the tumor microenvironment and therapy responses. It highlights that endothelial cells and pericytes are not only important in maintaining blood vessel structure in cancer, but that their signaling roles are a pivotal regulatory element harnessed by tumors, some of which could be targeted for alternative cancer treatment strategies. Here, we summarize current research targeting angiocrine and pericrine signaling in cancer and propose new approaches for thorough exploration of these networks to further disentangle the intricate mechanisms at play.","PeriodicalId":20193,"journal":{"name":"Physiological reviews","volume":"14 1","pages":""},"PeriodicalIF":33.6,"publicationDate":"2025-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144693431","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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