Plastic and Reconstructive Surgery Global Open最新文献_第8页

Viewtify: A Three-Dimensional Real-Time Computer Graphic Software that Allows for Clear Visualization of Tiny Vessels of Surgical Importance. Viewtify：一种三维实时计算机图形软件，可以清晰地显示手术中重要的微小血管。

IF 1.8

Plastic and Reconstructive Surgery Global Open Pub Date : 2025-09-22 eCollection Date: 2025-09-01 DOI: 10.1097/GOX.0000000000007119

Motoi Kato, Haruno Furutani, Tatsuya Uchida, Shota Wakasaki, Tomoyuki Ota, Hiroshi Matsumoto

{"title":"Viewtify: A Three-Dimensional Real-Time Computer Graphic Software that Allows for Clear Visualization of Tiny Vessels of Surgical Importance.","authors":"Motoi Kato, Haruno Furutani, Tatsuya Uchida, Shota Wakasaki, Tomoyuki Ota, Hiroshi Matsumoto","doi":"10.1097/GOX.0000000000007119","DOIUrl":"10.1097/GOX.0000000000007119","url":null,"abstract":"Background: Preoperative evaluation of tiny blood vessels is critical in flap surgery to improve safety and postoperative outcomes. This study assessed the efficacy of Viewtify, a 3-dimensional computer graphics (3DCG) software, in evaluating vascular pedicle and perforator locations in free flap surgery.Methods: This retrospective study included 30 patients who underwent reconstructive surgery with a deep inferior epigastric artery perforator, profunda artery perforator, or fibular flaps between January 2021 and July 2024. The thickness of adipose tissue was measured using contrast-enhanced computed tomography at the flap harvest sites. Perforator visibility scores were assigned based on 3D reconstructed images from Viewtify, and correlations with patient factors (age, body mass index, and adipose thickness) were analyzed.Results: Vascular pedicle was successfully identified in all patients. The perforator visibility was higher in the abdomen (4.9 ± 0.16) and thigh (4.6 ± 0.42) than in the lower leg (3.1 ± 0.90) (P < 0.05). A significant positive correlation was found between adipose thickness and the perforator visibility score (r = 0.533, P = 0.0025); however, no significant correlations with other factors were observed.Conclusions: Viewtify is an effective method for visualizing tiny blood vessels during preoperative planning, particularly in areas with thicker adipose tissue. Its use may improve surgical safety and precision, particularly in flap surgery involving abdominal and thigh regions. Further studies are required to optimize the imaging protocols for areas with thinner adipose tissue, such as the lower legs.","PeriodicalId":20149,"journal":{"name":"Plastic and Reconstructive Surgery Global Open","volume":"13 9","pages":"e7119"},"PeriodicalIF":1.8,"publicationDate":"2025-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12453311/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145131750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Reverse-flow Thoracodorsal Artery: An Additional Perfusion Strategy for Breast Microsurgical Flaps. 逆流胸背侧动脉：乳腺显微外科皮瓣的额外灌注策略。

IF 1.8

Plastic and Reconstructive Surgery Global Open Pub Date : 2025-09-22 eCollection Date: 2025-09-01 DOI: 10.1097/GOX.0000000000007092

Benedetto Longo, Martina Giacalone, Gennaro D'Orsi, Elettra Gagliano, Lisa Vannucchi, Gianluca Vanni, Oreste Claudio Buonomo, Valerio Cervelli

{"title":"Reverse-flow Thoracodorsal Artery: An Additional Perfusion Strategy for Breast Microsurgical Flaps.","authors":"Benedetto Longo, Martina Giacalone, Gennaro D'Orsi, Elettra Gagliano, Lisa Vannucchi, Gianluca Vanni, Oreste Claudio Buonomo, Valerio Cervelli","doi":"10.1097/GOX.0000000000007092","DOIUrl":"10.1097/GOX.0000000000007092","url":null,"abstract":"Autologous tissue-based techniques, including the most popular abdominal perforator flaps, represent the gold standard for breast reconstruction following mastectomy. In microsurgical breast reconstruction, the axillary and internal mammary vessels are commonly used as recipient vessel systems. The axillary system offers multiple suitable and easily accessible vessels, although postradiation fibrosis or previous surgery may render their dissection challenging, requiring the adoption of alternative perfusion strategies. We report a series of 7 microsurgical breast reconstructions with abdominal perforator flaps, performed between January 2021 and February 2023, based on flap perfusion through retrograde flow from the thoracodorsal artery (TDA). The technique proved valuable in scenarios where axillary vessels were compromised or unavailable and the TDA had been divided, showcasing its potential as an alternative flap perfusion strategy. The availability of the reverse-flow TDA as a recipient vessel provides an additional option for surgeons facing challenges in recipient vessel selection, offering a solution for scenarios involving vessel damage, fibrosis, or unavailability. Furthermore, the reverse-flow TDA might be a valuable source for flap reperfusion in cases of surgical revisions and after failed flap revascularization.","PeriodicalId":20149,"journal":{"name":"Plastic and Reconstructive Surgery Global Open","volume":"13 9","pages":"e7092"},"PeriodicalIF":1.8,"publicationDate":"2025-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12453372/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145131668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nodule Formation Associated With Botulinum Neurotoxin Type A Injections: Potential Triggers in 23 Patients. A型肉毒杆菌神经毒素注射相关的结节形成：23例患者的潜在诱因

IF 1.8

Plastic and Reconstructive Surgery Global Open Pub Date : 2025-09-22 eCollection Date: 2025-09-01 DOI: 10.1097/GOX.0000000000007098

Laila Hassan, George Kroumpouzos

{"title":"Nodule Formation Associated With Botulinum Neurotoxin Type A Injections: Potential Triggers in 23 Patients.","authors":"Laila Hassan, George Kroumpouzos","doi":"10.1097/GOX.0000000000007098","DOIUrl":"10.1097/GOX.0000000000007098","url":null,"abstract":"The formation of nodules at injection sites following botulinum neurotoxin type A (BoNTA) treatment has recently been reported. This complication can cause significant distress for patients, primarily due to the uncertainty surrounding its etiology and progression, as well as the lack of established management strategies. However, this complication has not been thoroughly studied. In this retrospective series, we detailed 23 female participants aged between 35 and 65 years who developed nodules at the injection sites after receiving BoNTA. All participants experienced the formation of nodules within 24 hours of the procedure. We investigated potential triggers for this reaction, including infection, vaccination, and the diluent composition used in the injections. Notably, all patients had received the COVID-19 vaccine and booster before their BoNTA treatment. Management strategies implemented included oral antibiotics, oral serratiopeptidase, topical or systemic steroids, and oral antihistamines. The resolution times for the nodules after treatment ranged from a few days to 1 month. This complication may indicate an immediate hypersensitivity reaction. The potential association between this complication and the COVID-19 vaccination warrants further investigation. It is important to counsel patients about the benign nature of these complications.","PeriodicalId":20149,"journal":{"name":"Plastic and Reconstructive Surgery Global Open","volume":"13 9","pages":"e7098"},"PeriodicalIF":1.8,"publicationDate":"2025-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12453349/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145131683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Successful Treatment of Refractory Bilateral Leg Ulcers With an Adsorptive Blood-Purification Device. 吸附性血液净化装置成功治疗双侧腿部难治性溃疡。

IF 1.8

Plastic and Reconstructive Surgery Global Open Pub Date : 2025-09-22 eCollection Date: 2025-09-01 DOI: 10.1097/GOX.0000000000007127

Asako Iida, Goh Akiyama, Kaoruko Matsunami, Rei Ogawa

引用次数: 0

Acoustic Analyses of the Digital Doppler Allen Test. 数字多普勒艾伦试验的声学分析。

IF 1.8

Plastic and Reconstructive Surgery Global Open Pub Date : 2025-09-22 eCollection Date: 2025-09-01 DOI: 10.1097/GOX.0000000000007110

Koichi Kobayashi, Runa Sugawara, Ken Nishimura, Naoko Masuyama

{"title":"Acoustic Analyses of the Digital Doppler Allen Test.","authors":"Koichi Kobayashi, Runa Sugawara, Ken Nishimura, Naoko Masuyama","doi":"10.1097/GOX.0000000000007110","DOIUrl":"10.1097/GOX.0000000000007110","url":null,"abstract":"Background: In this study, we aimed to perform noninvasive acoustic quantification of digital arterial Doppler sounds and to determine the possibility of evaluating digital arterial circulation using the results of acoustic assessment.Methods: In this prospective study, we recorded the Doppler sounds of the radial and ulnar digital arteries of all digits of 25 volunteers (male, n = 10; female, n = 15) included in the study, converted these recordings into digital files, and analyzed them using a fast Fourier transform analyzer. We recorded the Doppler sound of each digital artery by means of (1) contralateral digital artery compression, (2) ipsilateral digital artery compression, and (3) no compression as a control. The analyzed parameters comprised the equivalent sound level (Leq), sound pressure difference between the maximum and minimum sound pressures (delta sound pressure), and frequency. In addition, the Doppler sounds of the contralateral and compression groups were acoustically compared with those of the control group by 2 examiners.Results: The contralateral compression group demonstrated a statistically lower Leq and greater delta sound pressure. In particular, the delta sound pressure had a higher sensitivity and specificity. The ipsilateral compression group had a significantly lower Leq and frequency. The Doppler sounds of the contralateral compression group resembled a staccato rhythm. The agreement rate of the kappa coefficients was high.Conclusions: The patency of the digital artery is presumably high if the Doppler sound changes to a staccato rhythm upon compression of the contralateral digital artery.","PeriodicalId":20149,"journal":{"name":"Plastic and Reconstructive Surgery Global Open","volume":"13 9","pages":"e7110"},"PeriodicalIF":1.8,"publicationDate":"2025-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12453366/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145131713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Application of a Flash Glucose Monitoring System for the Evaluation of Blood Flow in Free Flaps. 瞬时血糖监测系统在自由皮瓣血流评估中的应用。

IF 1.8

Plastic and Reconstructive Surgery Global Open Pub Date : 2025-09-22 eCollection Date: 2025-09-01 DOI: 10.1097/GOX.0000000000007131

Hitoshi Nemoto, Daiki Morita, Miyu Yoshizawa, Yukio Seki, Kotaro Imagawa, Yotaro Tsunoda, Chieko Komaba, Ushio Hanai

{"title":"Application of a Flash Glucose Monitoring System for the Evaluation of Blood Flow in Free Flaps.","authors":"Hitoshi Nemoto, Daiki Morita, Miyu Yoshizawa, Yukio Seki, Kotaro Imagawa, Yotaro Tsunoda, Chieko Komaba, Ushio Hanai","doi":"10.1097/GOX.0000000000007131","DOIUrl":"10.1097/GOX.0000000000007131","url":null,"abstract":"Background: The key to salvaging free flaps following postoperative hemodynamic compromise is early detection and prompt intervention. Although clinical examinations, such as observing flap color, are often used for monitoring, they are subjective and have limited accuracy. This underscores the need for a low-cost, simple, and objective alternative. A potential solution is the use of a flash glucose monitoring (FGM) system for flap monitoring. In this study, we retrospectively investigated whether FGM is beneficial for monitoring flap blood flow.Methods: We retrospectively evaluated the medical records of patients who underwent breast reconstruction using a deep inferior epigastric perforator flap transfer. An FGM sensor was applied to each monitoring flap, and interstitial fluid glucose (IFG) levels were measured regularly during a 7-day postoperative period.Results: A total of 37 flaps were evaluated. Five flaps required surgical revision due to hemodynamic compromise; 1, in a patient with diabetes, completely failed, whereas 3 were successfully salvaged. The remaining flap developed arterial occlusion on the sixth day and was partially necrotic. In all cases requiring revision, except for the patient with diabetes, IFG levels dropped to less than 40 mg/dL before any clinical examination changes were observed. The IFG cutoff value, defined as less than 40 mg/dL, was calculated to have 100% sensitivity and 91% specificity within 48 hours postoperatively, with a negative predictive value of 100%.Conclusions: Measuring IFG using FGM is a noncontact, simple, and low-cost method. This method can provide a highly effective screening method for human and economic resource use.","PeriodicalId":20149,"journal":{"name":"Plastic and Reconstructive Surgery Global Open","volume":"13 9","pages":"e7131"},"PeriodicalIF":1.8,"publicationDate":"2025-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12453357/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145131685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Role of Urinary Bladder Matrix in Preserving Length and Function After Fingertip Injury. 膀胱基质在指尖损伤后保持长度和功能中的作用。

IF 1.8

Plastic and Reconstructive Surgery Global Open Pub Date : 2025-09-22 eCollection Date: 2025-09-01 DOI: 10.1097/GOX.0000000000007011

Meghan C McCullough, Peggy J Ebner, Theodore Brown, Eva Williams, Kylie Tanabe, Haben Berihun, Stuart Kuschner, Vahe Yacoubian, David A Kulber

{"title":"The Role of Urinary Bladder Matrix in Preserving Length and Function After Fingertip Injury.","authors":"Meghan C McCullough, Peggy J Ebner, Theodore Brown, Eva Williams, Kylie Tanabe, Haben Berihun, Stuart Kuschner, Vahe Yacoubian, David A Kulber","doi":"10.1097/GOX.0000000000007011","DOIUrl":"10.1097/GOX.0000000000007011","url":null,"abstract":"Background: Fingertip injuries are an overwhelmingly common but potentially debilitating injury. Preservation of functional length with restoration of sensate, supple tissue is the primary goal of reconstruction. Urinary bladder matrix (UBM) can serve as a tissue regenerator and replacement that can be kept moist with a dual-layer dressing, reducing painful dressing changes to every 10 days.Methods: A retrospective review was performed analyzing all patients treated with UBM for hand and finger injuries at a single institution between 2020 and early 2024. Patient demographics were recorded, including age, sex, level of injury, mechanism of injury, and prior treatments. Surgical outcomes, including time to wound healing, necessity of skin grafting, and postoperative complications, were collected.Results: A total of 23 cases were identified. Mechanisms of injury included traumatic amputation/crush (n = 10), burn injury (n = 1), dog bite (n = 1), ballistic trauma (n = 1), cancer excision (n = 1), septic flexor tenosynovitis requiring debridement (n = 1), and ischemic necrosis (n = 8). All patients underwent surgical debridement followed by application of UBM. Six of 23 patients required secondary skin grafting to achieve full healing. The product was successfully used after preexisting infection in 3 cases. The average time to wound healing was 9.8 weeks (SD 3.4 wk).Conclusions: Fingertip injuries represent a common but challenging reconstructive problem. UBM is a viable alternative to secondary intention healing for fingertip injuries and allows for regeneration of the soft tissue envelope and preservation of length.","PeriodicalId":20149,"journal":{"name":"Plastic and Reconstructive Surgery Global Open","volume":"13 9","pages":"e7011"},"PeriodicalIF":1.8,"publicationDate":"2025-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12453368/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145131670","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Excess Horizontal Breast Skin Facilitates a Simpler Wise Pattern Split Reduction Incision for Superficial Cancers. 多余的水平乳房皮肤有助于更简单的明智模式分裂减少切口浅表癌。

IF 1.8

Plastic and Reconstructive Surgery Global Open Pub Date : 2025-09-19 eCollection Date: 2025-09-01 DOI: 10.1097/GOX.0000000000007115

Jean-Claude D Schwartz

{"title":"Excess Horizontal Breast Skin Facilitates a Simpler Wise Pattern Split Reduction Incision for Superficial Cancers.","authors":"Jean-Claude D Schwartz","doi":"10.1097/GOX.0000000000007115","DOIUrl":"10.1097/GOX.0000000000007115","url":null,"abstract":"The Wise pattern split reduction (WPSR) incision is useful in patients with cancers near a skin margin that lies outside of the standard pattern. Instead of resecting skin in the standard inferolateral or inferomedial sections of the breast, this modified Wise pattern preserves this skin and instead resects skin over the tumor, ensuring a clear anterior margin and shifting the scar onto the breast instead of the medial or lateral inframammary fold. This approach makes use of the excess vertical skin of the breast. We have found that in certain situations, a WPSR incision can instead rely on the excess horizontal skin of the breast (the skin between the preoperatively drawn medial and lateral vertical limbs). This modification is useful for superficial, smaller, less extensive cancers that lie just medial or lateral to the preoperative Wise pattern vertical limb markings, resulting in a smaller final scar and a less extensive and complex surgical procedure. Patients with breast cancer were recruited into this study retrospectively after either a preoperative or intraoperative decision was made to use a WPSR incision using horizontal skin excess. This report summarized our experience with 10 consecutive patients who successfully underwent this approach to facilitate a clear anterior margin.","PeriodicalId":20149,"journal":{"name":"Plastic and Reconstructive Surgery Global Open","volume":"13 9","pages":"e7115"},"PeriodicalIF":1.8,"publicationDate":"2025-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12448158/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145113694","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Novel Use of a Synthetic Electrospun Wound Matrix in an Extensive Forearm Degloving Injury: Case Report and Review of the Literature. 合成静电纺伤口基质在前臂大面积脱手套损伤中的新应用：病例报告和文献回顾。

IF 1.8

Plastic and Reconstructive Surgery Global Open Pub Date : 2025-09-19 eCollection Date: 2025-09-01 DOI: 10.1097/GOX.0000000000007094

Karina A Tacconi, Augustine J Deering, Mahdi Malekpour, Howard T Wang

{"title":"Novel Use of a Synthetic Electrospun Wound Matrix in an Extensive Forearm Degloving Injury: Case Report and Review of the Literature.","authors":"Karina A Tacconi, Augustine J Deering, Mahdi Malekpour, Howard T Wang","doi":"10.1097/GOX.0000000000007094","DOIUrl":"10.1097/GOX.0000000000007094","url":null,"abstract":"Wound matrices, such as synthetic electrospun fiber matrices (SEFMs), provide innovative scaffolds to allow for complex wound healing. This case report described a 74-year-old woman with an 80% degloving injury of the left forearm caused by a fall. Due to her medical history, including liver cirrhosis, malnutrition, and previous orthopedic injuries, traditional skin grafting was deemed too risky. Instead, following initial debridement and application of negative pressure wound therapy, an SEFM sheet was applied and later supplemented with 5 applications of particulate SEFM. In subsequent follow-up visits, granulation tissue and wound closure progressed. By postoperative day 96, the wound was mostly healed with minimal residual erythema and full restoration of functionality. This case highlights the efficacy of SEFM in managing extensive injuries, providing an alternative for large, complex wounds, especially for patients with significant comorbidities who are poor candidates for traditional skin grafting.","PeriodicalId":20149,"journal":{"name":"Plastic and Reconstructive Surgery Global Open","volume":"13 9","pages":"e7094"},"PeriodicalIF":1.8,"publicationDate":"2025-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12448156/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145113737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of Platelet-rich Plasma and Brief Electrical Stimulation Following Facial Nerve Neurorrhaphy in a Rat Model. 富血小板血浆和短暂电刺激对面神经缝合大鼠模型的影响。

IF 1.8

Plastic and Reconstructive Surgery Global Open Pub Date : 2025-09-19 eCollection Date: 2025-09-01 DOI: 10.1097/GOX.0000000000007104

Janelle Sloychuk, Jin Soo Song, Lin Fu Zhu, Adrian Mendez, Jillian Querney, David Côté

{"title":"Effect of Platelet-rich Plasma and Brief Electrical Stimulation Following Facial Nerve Neurorrhaphy in a Rat Model.","authors":"Janelle Sloychuk, Jin Soo Song, Lin Fu Zhu, Adrian Mendez, Jillian Querney, David Côté","doi":"10.1097/GOX.0000000000007104","DOIUrl":"10.1097/GOX.0000000000007104","url":null,"abstract":"Background: With ongoing investigations to improve facial nerve recovery after injury, brief electrical stimulation (BES) and platelet-rich plasma (PRP) application have become promising modalities. The usage of combined modalities has not yet been investigated. We aimed to evaluate differences in facial nerve regeneration between rats receiving BES (group 1) and rats receiving BES plus PRP (group 2) following transection and primary neurorrhaphy.Methods: This was a prospective randomized animal study of 2 groups of 6 rats that underwent facial nerve transection and repair at the main trunk of the nerve. Both groups received BES on postoperative day 0 for 1 hour using an implantable stimulation device, with group 2 additionally receiving concurrent PRP. The primary measure of whisker amplitude was recorded from 2 to 8 weeks postoperatively.Results: At week 2, the average whisker amplitude for groups 1 and 2 was 6.5 and 2.0 degrees, respectively. At week 4, group 1 remained unchanged at 6.1 degrees, whereas group 2 improved to 10.1 degrees. By 6 weeks, average amplitudes were 8.2 and 14.0 degrees, respectively. By week 8, measures were 9.8 and 16.7 degrees, respectively. All results were statistically significant (P < 0.05).Conclusions: Application of BES and PRP following neurorrhaphy in a rat model yields a greater effect than BES alone in expediting facial nerve recovery.","PeriodicalId":20149,"journal":{"name":"Plastic and Reconstructive Surgery Global Open","volume":"13 9","pages":"e7104"},"PeriodicalIF":1.8,"publicationDate":"2025-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12448167/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145113652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0