Photodermatology, photoimmunology & photomedicine最新文献_第8页

Treatment with a red-laser-based wound therapy device exerts positive effects in models of delayed keratinocyte and fibroblast wound healing. 基于红色激光的伤口治疗装置对延迟角化细胞和成纤维细胞伤口愈合模型具有积极作用。

IF 2.6 4区医学

Photodermatology, photoimmunology & photomedicine Pub Date : 2024-01-01 Epub Date: 2023-11-13 DOI: 10.1111/phpp.12926

Cornelia Wiegand, Annegret Dirksen, Jörg Tittelbach

{"title":"Treatment with a red-laser-based wound therapy device exerts positive effects in models of delayed keratinocyte and fibroblast wound healing.","authors":"Cornelia Wiegand, Annegret Dirksen, Jörg Tittelbach","doi":"10.1111/phpp.12926","DOIUrl":"10.1111/phpp.12926","url":null,"abstract":"Background: Light therapy is widely used in medicine. Specifically, photobiomodulation has been shown to exert beneficial effects in wound healing disorders, which present a major challenge in health care. The study's aim was providing information on the effect of a novel, red-laser-based wound therapy device (WTD) on keratinocytes and fibroblasts during wound healing under optimal and non-optimal conditions.Methods: The scratch wound assay was employed as a wound healing model for mechanical damage with readjustment of specific cell milieus, explicitly chronic TH1 inflammation and TH2-dominant conditions. Furthermore, gene expression analysis of pro-inflammatory cytokines (IL1A, IL6, CXCL8), growth factors (TGFB1, PDGFC), transcription factors (NFKB1, TP53) and heat shock proteins (HSP90AA1, HSPA1A, HSPD1) as well as desmogleins (DSG1, DSG3) in keratinocytes and collagen (COL1A1, COL3A1) in fibroblasts was performed after WTD treatment.Results: It was shown that WTD treatment is biocompatible and supports scratch wound closure under non-optimal conditions. A distinct enhancement of desmoglein and collagen gene expression as well as induction of early growth factor gene expression was observed under chronic inflammatory conditions. Moreover, WTD increased HSPD1 transcript levels in keratinocytes and augmented collagen expression in fibroblasts during wound healing under TH2 conditions. WTD treatment also alleviated the inflammatory response in keratinocytes and induced early growth factor gene expression in fibroblasts under physiological conditions.Conclusion: Positive effects described for wound treatment with WTD could be replicated in vitro and seem to be to be conferred by a direct influence on cellular processes taking place in keratinocytes and fibroblasts during wound healing.","PeriodicalId":20123,"journal":{"name":"Photodermatology, photoimmunology & photomedicine","volume":" ","pages":"e12926"},"PeriodicalIF":2.6,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"92156000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A narrative review of the impact of ultraviolet radiation and sunscreen on the skin microbiome 紫外线辐射和防晒霜对皮肤微生物群影响的叙述性综述

IF 2.6 4区医学

Photodermatology, photoimmunology & photomedicine Pub Date : 2023-12-30 DOI: 10.1111/phpp.12943

Garett J. Grant, Indermeet Kohli, Tasneem F. Mohammad

引用次数: 0

Evaluating the factors influencing sun protection factors (SPF): Pooling data from multiple studies involving two reference ISO 24444:2019 sunscreen products (P2 and P8) 评估影响防晒系数（SPF）的因素：汇集涉及两种 ISO 24444:2019 防晒产品（P2 和 P8）的多项研究数据

IF 2.6 4区医学

Photodermatology, photoimmunology & photomedicine Pub Date : 2023-12-29 DOI: 10.1111/phpp.12942

Corinne Granger, Carles Trullàs, Nusayha Bibi Sokeechand, Eric Jourdan, Jean Krutmann, Veronique Francois-Newton, Muzzammil Hosenally

引用次数: 0

Skin cancer survivorship and sun protection behaviors in the United States 美国的皮肤癌幸存者和防晒行为

IF 2.6 4区医学

Photodermatology, photoimmunology & photomedicine Pub Date : 2023-12-29 DOI: 10.1111/phpp.12933

Daniela L. Domínguez Bueso, Liza M. González Ruiz, Lía I. Mondragón Márquez, Jason J. Liu

引用次数: 0

Estimation of serum and tissue level of interleukin-15 (IL-15) and IL-15 receptor alpha (IL-15Rα) in mycosis fungoides before and after phototherapy: An interventional cohort study 光疗前后真菌病患者血清和组织中白细胞介素-15（IL-15）及IL-15受体α（IL-15Rα）水平的估计：介入性队列研究

IF 2.6 4区医学

Photodermatology, photoimmunology & photomedicine Pub Date : 2023-12-29 DOI: 10.1111/phpp.12938

Rania M Mogawer, Randa Youssef, Kholoud Helmy, Nourhan Emad, Olfat Shaker, Sarah Orabi

引用次数: 0

Skin cancer prevention in extreme sports: Intervention in a 24-h race 极限运动中的皮肤癌预防：24 小时竞赛中的干预措施

IF 2.6 4区医学

Photodermatology, photoimmunology & photomedicine Pub Date : 2023-12-29 DOI: 10.1111/phpp.12940

Alba Rodríguez Martínez, Carmen Vaz Pardal, José Aguilera Arjona, Francisco Rivas Ruiz, Diego Doncel Molinero, Manuel Ruiz Paulano, Andras Subert, Jose Vicente Gutiérrez Manzanedo, Jacobo Cambil Martín, Maria Victoria de Gálvez Aranda, Leocricia Jiménez López, Nuria Blázquez Sánchez, Magdalena de Troya Martín

引用次数: 0

Evaluation of the protection of sunscreen products against long wavelength ultraviolet A1 and visible light-induced biological effects 评估防晒产品对长波长紫外线 A1 和可见光诱导的生物效应的保护作用

IF 2.6 4区医学

Photodermatology, photoimmunology & photomedicine Pub Date : 2023-12-08 DOI: 10.1111/phpp.12937

Nneamaka Ezekwe, Aunna Pourang, Alexis B. Lyons, Shanthi Narla, Amruth Atyam, Shereen Zia, Ben J. Friedman, Iltefat H. Hamzavi, Henry W. Lim, Indermeet Kohli

引用次数: 0

Sunburn and sun protection during recreational outdoor sport in summer: Findings from the German general population aged 16-65 years. 夏季休闲户外运动中的晒伤和防晒:来自德国16-65岁普通人群的调查结果。

IF 2.6 4区医学

Photodermatology, photoimmunology & photomedicine Pub Date : 2023-11-01 Epub Date: 2023-07-06 DOI: 10.1111/phpp.12898

Tatiana Görig, Christian Apfelbacher, Karl Philipp Drewitz, Anne Kerstin Reimers, Eckhard W Breitbart, Katharina Diehl

{"title":"Sunburn and sun protection during recreational outdoor sport in summer: Findings from the German general population aged 16-65 years.","authors":"Tatiana Görig, Christian Apfelbacher, Karl Philipp Drewitz, Anne Kerstin Reimers, Eckhard W Breitbart, Katharina Diehl","doi":"10.1111/phpp.12898","DOIUrl":"10.1111/phpp.12898","url":null,"abstract":"Background: Sunburn can increase one's risk of developing skin cancer. We aimed to quantify the prevalence of sunburn during recreational outdoor sport (ROS) in summer, to explore the use of different sun protection measures, and to examine factors associated with sunburn during ROS using a population-based sample from Germany.Methods: For this cross-sectional study, 2081 individuals aged 16-65 years who reported being engaged in ROS in summer were surveyed via standardized telephone interviews in 2020 (National Cancer Aid Monitoring, NCAM).Results: Overall, 16.7% reported experiencing at least one sunburn during ROS in the past twelve months. Sunburn occurrence was negatively associated with the age of the participants (e.g. OR = 0.49 in 56-65 year-olds, p < .001), and positively associated with skin type I/II (OR = 1.55, p < .001) and with having a higher number of nevi (OR = 1.42, p = .005). While wearing sleeved shirts was the most frequently-used sun protection measure during ROS (74.9%), wearing headgear was least common in our sample (29.0%). In multivariate analyses, sunburn was positively associated with the use of sun protection measures (e.g. OR = 1.32 for wearing sleeved shirts, p = .02).Conclusions: Our nationwide data show that ROS is one of the settings where sun protection should play a greater role. Especially in organized sports, particular attention should be devoted to organizational (e.g. exercise outside peak hours) or contextual measures (e.g. shade by the natural or built environment) to prevent skin cancer in later life.","PeriodicalId":20123,"journal":{"name":"Photodermatology, photoimmunology & photomedicine","volume":" ","pages":"589-597"},"PeriodicalIF":2.6,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9758890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Impact of ultraviolet radiation on cardiovascular and metabolic disorders: The role of nitric oxide and vitamin D. 紫外线辐射对心血管和代谢紊乱的影响：一氧化氮和维生素D的作用。

IF 2.6 4区医学

Photodermatology, photoimmunology & photomedicine Pub Date : 2023-11-01 Epub Date: 2023-09-20 DOI: 10.1111/phpp.12914

Qing-Ling Quan, Kyeong-No Yoon, Ji Su Lee, Eun Ju Kim, Dong Hun Lee

{"title":"Impact of ultraviolet radiation on cardiovascular and metabolic disorders: The role of nitric oxide and vitamin D.","authors":"Qing-Ling Quan, Kyeong-No Yoon, Ji Su Lee, Eun Ju Kim, Dong Hun Lee","doi":"10.1111/phpp.12914","DOIUrl":"10.1111/phpp.12914","url":null,"abstract":"Background/purpose: Ultraviolet (UV) radiation has both harmful and beneficial effects on human skin and health. It causes skin damage, aging, and cancer; however, it is also a primary source of vitamin D. Additionally, UV radiation can impact energy metabolism and has protective effects on several cardiovascular and metabolic disorders in mice and humans. However, the mechanisms of UV protection against these diseases have not been clearly identified.Methods: This review summarizes the systemic effects of UV radiation on hypertension and several metabolic diseases such as obesity, diabetes, and nonalcoholic fatty liver disease (NAFLD) in mice, and we also consider the mechanisms of action of the related regulators nitric oxide (NO) and vitamin D.Results: UV exposure can lower blood pressure and prevent the development of cardiovascular diseases and metabolic disorders, such as metabolic syndrome, obesity, and type 2 diabetes, primarily through mechanisms that depend on UV-induced NO. UV radiation may also effectively delay the onset of type 1 diabetes through mechanisms that rely on UV-induced vitamin D. UV-induced NO and vitamin D play roles in preventing and slowing the progression of NAFLD.Conclusion: UV exposure is a promising nonpharmacological intervention for cardiovascular and metabolic disorders. NO and vitamin D may play a crucial role in mediating these effects. However, further investigations are required to elucidate the exact mechanisms and determine the optimal dosage and exposure duration of UV radiation.","PeriodicalId":20123,"journal":{"name":"Photodermatology, photoimmunology & photomedicine","volume":" ","pages":"573-581"},"PeriodicalIF":2.6,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41176955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical and dermoscopic assessment of ablative carbon dioxide laser versus intradermal heparin sodium in xanthelasma. 消融二氧化碳激光与皮内肝素钠治疗黄褐斑的临床和皮肤镜评估。

IF 2.6 4区医学

Photodermatology, photoimmunology & photomedicine Pub Date : 2023-11-01 Epub Date: 2023-09-29 DOI: 10.1111/phpp.12915

Yomna Mazid El-Hamd Neinaa, Bassant Sherif El-Sayed Awara, Osama El-Said Shalaby, Naeim Mohammed Abd El-Naby

{"title":"Clinical and dermoscopic assessment of ablative carbon dioxide laser versus intradermal heparin sodium in xanthelasma.","authors":"Yomna Mazid El-Hamd Neinaa, Bassant Sherif El-Sayed Awara, Osama El-Said Shalaby, Naeim Mohammed Abd El-Naby","doi":"10.1111/phpp.12915","DOIUrl":"10.1111/phpp.12915","url":null,"abstract":"Background: Ablative carbon dioxide (CO2 ) laser is still a cornerstone in the management of xanthelasma. However, post-laser complications such as post-inflammatory hyperpigmentation or scarring have to be considered. Heparin sodium was recently suggested as an effective therapeutic modality for xanthelasma.Objective: The aim of this work was to compare the therapeutic value of ablative CO2 laser versus intradermal heparin sodium in xanthelasma.Methods: This study was piloted on 30 xanthelasma patients, whose lesions were randomly categorized into two groups. Group A was managed with CO2 laser ablation (2 sessions scheduled every 4 weeks), whereas Group B was managed with intradermal heparin sodium injections (10 sessions scheduled every week). Pre- and post-treatments evaluations were done both clinically and dermoscopically.Results: Significant reduction of xanthelasma lesions was reported in response to both therapeutic interventions. However, the ablative CO2 laser was more significantly effective than intradermal heparin sodium. Interestingly, intradermal injection of heparin sodium was nearly as effective as ablative CO2 laser in early (<2 years duration) grade I and II xanthelasma, with a lower incidence of post-therapy side effects.Conclusions: Intradermal injection of heparin sodium could be suggested as a safe and cost-effective therapeutic technique for early mild grade I and II xanthelasma. Moreover, it could be recommended as a pre-operative management of grade III and IV xanthelasma to reduce the lesions to be easily ablated with CO2 laser.","PeriodicalId":20123,"journal":{"name":"Photodermatology, photoimmunology & photomedicine","volume":" ","pages":"648-656"},"PeriodicalIF":2.6,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41140746","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0