Photomedicine and laser surgery最新文献

{"title":"Effective Use of Nonablative Fractional Laser on Multiple Whip Scars.","authors":"Santo Mercuri,&nbsp;Pina Brianti,&nbsp;Enza Cestone,&nbsp;Annunziata Dattola,&nbsp;Steven Paul Nisticò","doi":"10.1089/pho.2017.4370","DOIUrl":"https://doi.org/10.1089/pho.2017.4370","url":null,"abstract":"<p><strong>Background: </strong>Laser technology provides different solutions for scar treatment from the traditional ablative lasers to the more recent fractional devices.</p><p><strong>Patients and methods: </strong>We present the case of a young woman treated for scars induced by severe whipping since the age of 10. She received four monthly nonablative fractional 1550 nm erbium glass laser treatments. Fluence used was 20 mJ/cm² with 1500 microthermal zones/cm².</p><p><strong>Results: </strong>Significant improvement was documented in the color and texture of the lesion at the end of treatment and at follow-up. Treatment had no major side effects and was well tolerated.</p><p><strong>Conclusions: </strong>We believe that nonablative fractional lasers, used mainly for cosmetic purposes, may be useful in managing post-traumatic scars as well.</p>","PeriodicalId":20117,"journal":{"name":"Photomedicine and laser surgery","volume":"36 6","pages":"337-339"},"PeriodicalIF":0.0,"publicationDate":"2018-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1089/pho.2017.4370","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35786908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of 810 nm Near-Infrared Laser on Revascularization of Ischemic Flaps in Rats.","authors":"Jian-Xun Ma,&nbsp;Qing-Mo Yang,&nbsp;You-Chen Xia,&nbsp;Wei-Guang Zhang,&nbsp;Fang-Fei Nie","doi":"10.1089/pho.2017.4360","DOIUrl":"https://doi.org/10.1089/pho.2017.4360","url":null,"abstract":"<p><strong>Objective: </strong>To investigate the effect of 810 nm near-infrared (NIR) laser on the revascularization of ischemic flaps.</p><p><strong>Background: </strong>It has long been proved that photobiomodulation therapy (PBMT) improves the blood supply of flaps. NIR laser improves the treatment of hypodermis-located lesions and of flap survival, but basic research on the use of 810 nm NIR laser for ischemic flap revascularization is still lacking.</p><p><strong>Materials and methods: </strong>We prepared two symmetrical long random-pattern flaps on the backs of 60 rats. Each flap was 6 cm long, 1 cm wide, and 1 cm to the middle line. The flaps were divided into an irradiated flap group and an internal control group. The irradiated flaps underwent postoperative 810 nm laser therapy with the energy density of 11.30 J/cm² daily. The control flaps were covered by stainless steel to avoid laser irradiation. We observed the viability of the flaps. The flaps underwent Hematoxylin and Eosin (H&E) staining for the observation of histomorphology, immunohistochemical staining of factor VIII for the capillary count, α-smooth muscle actin for the small arterial count, and vascular endothelial growth factor for the integrated optical density (OD) of the positive stained color.</p><p><strong>Results: </strong>The irradiated flaps showed significantly better flap survival than the control flaps. H&E staining showed that the irradiated flaps had clear tissue structure and little inflammatory cell infiltration. The control flaps demonstrated comparatively worse results. Vascular endothelial growth factor staining showed that the difference in integrated OD between the irradiated flaps and the control flaps was not statistically significant. α-smooth muscle actin and factor VIII staining showed significantly greater numbers of arterioles and capillaries in the irradiated flaps than the control flaps after 4 days of irradiation.</p><p><strong>Conclusions: </strong>PBMT with 810 nm NIR laser could enhance ischemic flap revascularization and increase flap viability.</p>","PeriodicalId":20117,"journal":{"name":"Photomedicine and laser surgery","volume":"36 6","pages":"290-297"},"PeriodicalIF":0.0,"publicationDate":"2018-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1089/pho.2017.4360","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36205268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Penile Lichen Sclerosus Treated with 1927 nm Thulium Fiber Laser and Photodynamic Therapy: A New Possible Therapeutic Approach.","authors":"Santo Raffaele Mercuri,&nbsp;Pina Brianti,&nbsp;Antonio Foti,&nbsp;Marco Bartolucci,&nbsp;Annunziata Dattola,&nbsp;Steven Paul Nisticò","doi":"10.1089/pho.2017.4386","DOIUrl":"https://doi.org/10.1089/pho.2017.4386","url":null,"abstract":"<p><strong>Objective: </strong>We treated two patients with recalcitrant lichen sclerosus (LS) of the penis with a combination of 1927 nm thulium fiber laser and methyl-aminolevulinate (MAL) photodynamic therapy (PDT).</p><p><strong>Background data: </strong>Therapy of LS is based on topical potent steroids, emollients, and topical calcineurin inhibitors. Circumcision is effective, but not always accepted. PDT represents a valid therapeutic option in refractory cases, but there are no reports about the association with 1927 nm thulium laser in the treatment of this pathology.</p><p><strong>Materials and methods: </strong>We used to treat the affected areas with a combination of 1927 nm thulium fiber laser and MAL PDT in the same section. The same protocol was repeated after 1 month.</p><p><strong>Results: </strong>An improvement of lesions after the first treatment and complete cleaning after 3 months of therapy were noted. Results were maintained in the follow-up after 2 years.</p><p><strong>Conclusions: </strong>Association with 1927 nm thulium laser was able to amplify the effectiveness of PDT and to promote tissue remodeling. Despite the positive response to our case, clinical studies are lacking and further analysis could be performed on a wider population to better define correct dosage and safety profile. Further, it is necessary to compare this procedure with other treatments to establish the real effectiveness.</p>","PeriodicalId":20117,"journal":{"name":"Photomedicine and laser surgery","volume":"36 6","pages":"333-336"},"PeriodicalIF":0.0,"publicationDate":"2018-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1089/pho.2017.4386","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35706856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Laser: The Light That Heals.","authors":"Farouk A H Al-Watban","doi":"10.1089/pho.2017.4432","DOIUrl":"https://doi.org/10.1089/pho.2017.4432","url":null,"abstract":"The instant images that leap to one's mind at the mention of the word \" Laser \" are of star wars and light sabers. The word has connotation of power almost akin to magic. The term LASER is an acronym that stands for Light Amplification by Stimulation Emission of Radiation. Laser is not a device; it is a phenomenon that has been applied for specific uses in a wide variety of fields particularly in medicine. For all its variety of applications, the principle behind the laser is quite simple; when an atom or molecule absorbs energy, electrons or molecules move into higher orbits and fall back almost immediately into lower orbits, as the electron molecule falls back into the lower energy level, a spark of surplus energy bursts out, this surplus energy is the \" photon \" , the basic unit of light. The stimulated emission used in laser takes place when a photon stimulates another atom in its path to emit an identical photon thus creating waves of light that are in perfect phase with each other. In a laser chamber which contains active medium, these waves of light are reflected back and forth by mirrors increasing in power and brightness with each reflection. The result is a highly monochromatic, Merely understanding the principle of the laser does not explain how this wonderful occurrence is harnessed in so many medical fields. In King Faisal Specialist Hospital and Research Centre, the laser is now used in different medical applications superseding some traditional methods of healing and diagnostics. specialty is laser radiation and photodynamic therapy says there are different types of lasers. There are for example the CO2 (Carbon Dioxide) laser, the Each kind of laser exhibit properties that make it suitable for specific medical applications the depending on its interaction with tissue. Dr. Watban says, \" What is the laser tissue interaction? We look to the main","PeriodicalId":20117,"journal":{"name":"Photomedicine and laser surgery","volume":"36 6","pages":"287-289"},"PeriodicalIF":0.0,"publicationDate":"2018-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1089/pho.2017.4432","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36022696","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intense Pulsed Light Applied Directly on Eyelids Combined with Meibomian Gland Expression to Treat Meibomian Gland Dysfunction.","authors":"Bei Rong,&nbsp;Yun Tang,&nbsp;Ping Tu,&nbsp;Ruixing Liu,&nbsp;Jing Qiao,&nbsp;Wenjing Song,&nbsp;Rolando Toyos,&nbsp;Xiaoming Yan","doi":"10.1089/pho.2017.4402","DOIUrl":"https://doi.org/10.1089/pho.2017.4402","url":null,"abstract":"<p><strong>Objective: </strong>To determine the efficacy and safety of intense pulsed light (IPL) applied directly on the eyelids and meibomian gland expression (MGX) in treating meibomian gland dysfunction (MGD).</p><p><strong>Background: </strong>IPL application on the periocular skin effectively improves meibomian gland secretion and tear film break-up time (TBUT) in patients with MGD/dry eye.</p><p><strong>Methods: </strong>This prospective, randomized, double-masked, controlled study involved 44 patients. One eye was randomly selected for IPL treatment; the other served as a control. Study eyes received three IPL treatments at 4-week intervals; IPL was applied directly on the eyelids, and the eye was protected with a Jaeger lid plate. Control eyes received sham IPL treatments. Both eyes received MGX and artificial tears. Meibomian gland yielding secretion score (MGYSS), TBUT, Standard Patient Evaluation of Eye Dryness (SPEED), cornea fluorescein staining (CFS), meibography, best corrected visual acuity (BCVA), intraocular pressure (IOP), and fundus examination were performed.</p><p><strong>Results: </strong>Compared to the baseline, MGYSS, TBUT, and SPEED and CFS scores improved in the study eyes, while only SPEED and CFS scores improved in the control eyes (p < 0.001 for all). Changes in MGYSS and TBUT were higher in the study eyes than in the control eyes (p < 0.05), but changes in SPEED and CFS scores were similar (p > 0.05). BCVA and IOP improved in both the study and control eyes (p < 0.05). Five patients experienced mild pain and burning during IPL treatment. One patient suffered partial eyelash loss.</p><p><strong>Conclusions: </strong>IPL combined with MGX safely and effectively treated MGD.</p>","PeriodicalId":20117,"journal":{"name":"Photomedicine and laser surgery","volume":"36 6","pages":"326-332"},"PeriodicalIF":0.0,"publicationDate":"2018-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1089/pho.2017.4402","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36037241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of Low-Power Light Therapy on the Tissue Repair Process of Chronic Wounds in Diabetic Feet.","authors":"Joelita de Alencar Fonseca Santos,&nbsp;Mariana Barbosa Dias Campelo,&nbsp;Rauirys Alencar de Oliveira,&nbsp;Renata Amadei Nicolau,&nbsp;Verônica Elis Araújo Rezende,&nbsp;Emilia Ângela Loschiavo Arisawa","doi":"10.1089/pho.2018.4455","DOIUrl":"https://doi.org/10.1089/pho.2018.4455","url":null,"abstract":"<p><strong>Objective: </strong>To analyze the efficacy of the therapeutic use of Low-Level Laser Therapy (LLLT) on the tissue repair process of chronic wounds in patients with diabetic feet through the analysis of Pressure Ulcer Scale for Healing (PUSH) scales, pain and the measurement done using the ImageJ^© software.</p><p><strong>Methods: </strong>This clinical trial was carried out with 18 patients 30-59 years of age, who had chronic wounds on their foot due to complications of diabetes mellitus. The patients were randomly allocated in two different groups of equal numbers: Control and Laser Groups. The LLLT equipment used in the research has a wavelength of 660 nm, 30 mW power, continuous mode emission, 6 J/cm² dosimetry, 48/48 h in a 4-week period. Measurement and the aspect of wounds were noted in the PUSH scale and the pain was evaluated weekly. The Mann-Whitney U nonparametric test was used to compare groups.</p><p><strong>Results: </strong>The Laser Group presented a significant increase of the tissue repair index when compared with the Control Group, with a significant statistical difference (p < 0.013). There was no significant difference between the groups in all the weeks using the PUSH scale.</p><p><strong>Conclusions: </strong>The use of LLLT on chronic wounds in a diabetic foot demonstrated efficacy on the progression of the tissue repair process in a short period.</p>","PeriodicalId":20117,"journal":{"name":"Photomedicine and laser surgery","volume":"36 6","pages":"298-304"},"PeriodicalIF":0.0,"publicationDate":"2018-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1089/pho.2018.4455","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36205209","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Histological and Thermometric Examination of Soft Tissue De-Epithelialization Using Digitally Controlled Er:YAG Laser Handpiece: An Ex Vivo Study.","authors":"Kinga Grzech-Leśniak,&nbsp;Jacek Matys,&nbsp;Kamil Jurczyszyn,&nbsp;Piotr Ziółkowski,&nbsp;Marzena Dominiak,&nbsp;Aldo Brugnera Junior,&nbsp;Umberto Romeo","doi":"10.1089/pho.2017.4413","DOIUrl":"https://doi.org/10.1089/pho.2017.4413","url":null,"abstract":"<p><strong>Objective: </strong>The purpose of this study was histological and thermometric examination of soft tissue de-epithelialization using digitally controlled laser handpiece (DCLH) - X-Runner.</p><p><strong>Background data: </strong>Commonly used techniques for de-epithelialization include scalpel, abrasion with diamond bur, or a combination of the two. Despite being simple, inexpensive and effective, these techniques are invasive and may produce unwanted side effects. It is important to look for alternative techniques using novel tools, which are minimally invasive and effective.</p><p><strong>Materials and methods: </strong>114 porcine samples sized 6 × 6 mm were collected from the attached gingiva (AG) of the alveolar process of the mandible using 15C scalpel blade. The samples were irradiated by means of Er:YAG laser (LightWalker, Fotona, Slovenia), using X-Runner and HO₂ handpieces at different parameters; 80, 100, and 140 mJ/20 Hz in time of 6 or 16 sec, respectively. The temperature was measured with a K-type thermocouple. For the histopathological analysis of efficiency of epithelium removal and thermal injury, 3 random samples were de-epithelialized with an HO₂ handpiece, and 9 random samples with an X-Runner handpiece with different parameters. For the samples irradiated with DCLH, we have used three different settings, which resulted in removing 1 to 3 layers of the soft tissue. The efficiency of epithelium removal and the rise of temperature were analyzed.</p><p><strong>Results: </strong>DCLH has induced significantly lower temperature increase compared with HO₂ at each energy to frequency ratio. The histological examination revealed total epithelium removal when HO₂ handpiece was used at 100 and 140 mJ/20 Hz and when DCLH was used for two- and threefold lasing at 80, 100, and 140 mJ/20 Hz.</p><p><strong>Conclusions: </strong>Er:YAG laser with DCLH handpiece may be an efficient tool in epithelium removal without excessive thermal damage.</p>","PeriodicalId":20117,"journal":{"name":"Photomedicine and laser surgery","volume":"36 6","pages":"313-319"},"PeriodicalIF":0.0,"publicationDate":"2018-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1089/pho.2017.4413","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35940525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Double Pass 595 nm Pulsed Dye Laser Does Not Enhance the Efficacy of Port Wine Stains Compared with Single Pass: A Randomized Comparison with Histological Examination.","authors":"Wenxin Yu,&nbsp;Jiafang Zhu,&nbsp;Lizhen Wang,&nbsp;Yajing Qiu,&nbsp;Yijie Chen,&nbsp;Xi Yang,&nbsp;Lei Chang,&nbsp;Gang Ma,&nbsp;Xiaoxi Lin","doi":"10.1089/pho.2017.4392","DOIUrl":"https://doi.org/10.1089/pho.2017.4392","url":null,"abstract":"<p><strong>Objective: </strong>To compare the efficacy and safety of double-pass pulsed dye laser (DWL) and single-pass PDL (SWL) in treating virgin port wine stain (PWS).</p><p><strong>Background: </strong>The increase in the extent of vascular damage attributed to the use of double-pass techniques for PWS remains inconclusive. A prospective, side-by-side comparison with a histological study for virgin PWS is still lacking.</p><p><strong>Materials and methods: </strong>Twenty-one patients (11 flat PWS, 10 hypertrophic PWS) with untreated PWS underwent 3 treatments at 2-month intervals. Each PWS was divided into three treatment sites: SWL, DWL, and untreated control. Chromametric and visual evaluation of the efficacy and evaluation of side effects were conducted 3 months after final treatment. Biopsies were taken at the treated sites immediately posttreatment.</p><p><strong>Results: </strong>Chromametric and visual evaluation suggested that DWL sites showed no significant improvement compared with SWL (p > 0.05) in treating PWS. The mean depth of photothermal damage to the vessels was limited to a maximum of 0.36-0.41 mm in both SWL and DWL sides. Permanent side effects were not observed in any patients.</p><p><strong>Conclusions: </strong>Double-pass PDL does not enhance PWS clearance. To improve the clearance of PWS lesions, either the depth of laser penetration should be increased or greater photothermal damage to vessels should be generated.</p>","PeriodicalId":20117,"journal":{"name":"Photomedicine and laser surgery","volume":"36 6","pages":"305-312"},"PeriodicalIF":0.0,"publicationDate":"2018-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1089/pho.2017.4392","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35954170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Retrospective Study on Laser Treatment of Oral Vascular Lesions Using the \"Leopard Technique\": The Multiple Spot Irradiation Technique with a Single-Pulsed Wave.","authors":"Hidetaka Miyazaki,&nbsp;Takafumi Ohshiro,&nbsp;Umberto Romeo,&nbsp;Tadahide Noguchi,&nbsp;Yutaka Maruoka,&nbsp;Gianfranco Gaimari,&nbsp;Georgi Tomov,&nbsp;Yoshitaka Wada,&nbsp;Kae Tanaka,&nbsp;Toshio Ohshiro,&nbsp;Shinichi Asamura","doi":"10.1089/pho.2017.4410","DOIUrl":"https://doi.org/10.1089/pho.2017.4410","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to retrospectively evaluate the efficacy and safety of laser treatment of oral vascular lesions using the multiple spot irradiation technique with a single-pulsed wave.</p><p><strong>Background data: </strong>In laser therapy for vascular lesions, heat accumulation induced by excessive irradiation can cause adverse events postoperatively, including ulcer formation, resultant scarring, and severe pain. To prevent heat accumulation and side effects, we have applied a multiple pulsed spot irradiation technique, the so-called \"leopard technique\" (LT) to oral vascular lesions. This approach was originally proposed for laser treatment of nevi. It can avoid thermal concentration at the same spot and spare the epithelium, which promotes smooth healing. The goal of the study was to evaluate this procedure and treatment outcomes.</p><p><strong>Patients and methods: </strong>The subjects were 46 patients with 47 oral vascular lesions treated with the LT using a Nd:YAG laser (1064 nm), including 24 thick lesions treated using a combination of the LT and intralesional photocoagulation.</p><p><strong>Results: </strong>All treatment outcomes were satisfactory without serious complications such as deep ulcer formation, scarring, bleeding, or severe swelling.</p><p><strong>Conclusions: </strong>Laser therapy with the LT is a promising less-invasive treatment for oral vascular lesions.</p>","PeriodicalId":20117,"journal":{"name":"Photomedicine and laser surgery","volume":"36 6","pages":"320-325"},"PeriodicalIF":0.0,"publicationDate":"2018-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1089/pho.2017.4410","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36061962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy and Safety of Photoselective Vaporization of the Prostate with 120 W 532 nm Laser in Patients with Benign Prostatic Hyperplasia on Anticoagulation or Antiplatelet Therapy: Observations on Long-Term Outcomes.","authors":"Grzegorz Piotrowicz,&nbsp;Tomasz Syryło,&nbsp;Rafał Jedynak,&nbsp;Henryk Zieliński","doi":"10.1089/pho.2017.4367","DOIUrl":"https://doi.org/10.1089/pho.2017.4367","url":null,"abstract":"<p><strong>Objective: </strong>The objective of this study was to evaluate the safety and effectiveness of photoselective vaporization of the prostate (PVP) in the treatment of patients with benign prostatic hyperplasia (BPH) on anticoagulant or antiplatelet therapy.</p><p><strong>Background: </strong>The \"gold standard\" of surgical treatment of BPH is transurethral resection of the prostate (TURP). Since the risk of complications associated with TURP is still significant, there is a continuous search for safer and equally effective procedures. One of them is PVP with a 532 nm potassium-titanyl-phosphate/lithium triborate (KTP/LBO) laser.</p><p><strong>Materials and methods: </strong>A total of 109 patients underwent PVP with the use of the GreenLight HPS 120 W laser. Sixty-five (59.6%) of the patients were on anticoagulants or antiplatelet drugs, whereas 44 (40.4%) patients were not. Various objective and subjective parameters were evaluated intra- and postoperatively along with a 5-year follow-up to compare the results and safety of PVP in these two groups of patients.</p><p><strong>Results: </strong>No difference between the groups was found in intraoperative parameters, including operation and lasing time, as well as laser energy used. Also, no intraoperative complications were observed. There was no significant bleeding in any of the groups, and none of the patients required a blood transfusion. Catheterization and hospitalization time did not differ between both groups, and during the 5-year follow-up period, good objective and subjective results were observed, and the complication rates were comparable between the groups.</p><p><strong>Conclusions: </strong>Our results demonstrate that PVP for patients with BPH is an effective and safe procedure with satisfactory long-term outcomes. Anticoagulant and antiplatelet drugs did not significantly influence the results, or the complication rates.</p>","PeriodicalId":20117,"journal":{"name":"Photomedicine and laser surgery","volume":"36 5","pages":"273-283"},"PeriodicalIF":0.0,"publicationDate":"2018-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1089/pho.2017.4367","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35636127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}