Pediatric Infectious Disease Journal最新文献

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Optimizing Early Diagnosis of Infectious Diseases in Migrant and Refugee Children: An Overview of Best Practices and Strategies. 优化移民和难民儿童传染病的早期诊断:最佳实践与策略概述》。
IF 2.9 4区 医学
Pediatric Infectious Disease Journal Pub Date : 2024-08-01 Epub Date: 2024-05-31 DOI: 10.1097/INF.0000000000004406
Sophie Pach, Nicole Ritz, Sarah Eisen
{"title":"Optimizing Early Diagnosis of Infectious Diseases in Migrant and Refugee Children: An Overview of Best Practices and Strategies.","authors":"Sophie Pach, Nicole Ritz, Sarah Eisen","doi":"10.1097/INF.0000000000004406","DOIUrl":"10.1097/INF.0000000000004406","url":null,"abstract":"","PeriodicalId":19858,"journal":{"name":"Pediatric Infectious Disease Journal","volume":null,"pages":null},"PeriodicalIF":2.9,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141237715","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of Pediatric HIV Postexposure Prophylaxis Guideline Following Child Sexual Assault in Western Australia. 西澳大利亚州儿童遭受性侵犯后儿科艾滋病暴露后预防指南评估》(Evaluation of Pediatric HIV Postexposure Prophylaxis Guideline Following Child Sexual Assault in Western Australia.
IF 2.9 4区 医学
Pediatric Infectious Disease Journal Pub Date : 2024-08-01 Epub Date: 2024-05-07 DOI: 10.1097/INF.0000000000004370
Momoko Combs, Alice Johnson, Joanne Abbotsford, Asha C Bowen, Charlie McLeod, David A Foley
{"title":"Evaluation of Pediatric HIV Postexposure Prophylaxis Guideline Following Child Sexual Assault in Western Australia.","authors":"Momoko Combs, Alice Johnson, Joanne Abbotsford, Asha C Bowen, Charlie McLeod, David A Foley","doi":"10.1097/INF.0000000000004370","DOIUrl":"10.1097/INF.0000000000004370","url":null,"abstract":"<p><strong>Background: </strong>HIV postexposure prophylaxis (PEP) following child sexual assault (CSA) is recommended in select cases. High rates of poor adherence to PEP are reported. We evaluated adherence to the recommended management of children following CSA at the tertiary pediatric facility in Western Australia and compared our approach with international guidelines.</p><p><strong>Methods: </strong>Medical records were reviewed for all children <16 years old assessed at Perth Children's Hospital between October 1, 2016 and November 30, 2020 following alleged CSA. Data, including exposure type, PEP adherence and follow-up, were collected. A review of contemporary national and international PEP guidelines was undertaken in parallel.</p><p><strong>Results: </strong>There were 511 alleged CSA events over the study period; 62/511 (12%) were appropriately risk-assessed as requiring PEP by the treating clinician. PEP was not prescribed in 8/62 (13%) events, with a reason documented for 6/8 (75%). Overall, less than half of children who were eligible for PEP were adherent to the 28-day regimen (23/54, 43%). Gastrointestinal upset contributed to early cessation in 5/54 (9%). Final 3-month blood-borne virus serology results were available in less than one in 3 children. A review of international clinical practice revealed significant heterogeneity of criteria for the provision of PEP and a paucity of pediatric-specific data.</p><p><strong>Conclusions: </strong>We identified several areas of our PEP management that required strengthening, with limited direction available in current international guidelines. We have adopted a broader use of fixed drug combinations and implemented a multifaceted follow-up program. It will be essential to review the impact of these changes.</p>","PeriodicalId":19858,"journal":{"name":"Pediatric Infectious Disease Journal","volume":null,"pages":null},"PeriodicalIF":2.9,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140877003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bursting, but Not in a Good Way. 爆裂,但不是好事。
IF 2.9 4区 医学
Pediatric Infectious Disease Journal Pub Date : 2024-08-01 Epub Date: 2024-07-10 DOI: 10.1097/INF.0000000000004316
Laila Al Yazidi, Mariam Bourdoucen, Tahani Al Mughaizwi, Sameer Bhimjibhai Raniga, Fatma Al Farsi, Badriya Al Adawi, Salem Al-Tamemi
{"title":"Bursting, but Not in a Good Way.","authors":"Laila Al Yazidi, Mariam Bourdoucen, Tahani Al Mughaizwi, Sameer Bhimjibhai Raniga, Fatma Al Farsi, Badriya Al Adawi, Salem Al-Tamemi","doi":"10.1097/INF.0000000000004316","DOIUrl":"https://doi.org/10.1097/INF.0000000000004316","url":null,"abstract":"","PeriodicalId":19858,"journal":{"name":"Pediatric Infectious Disease Journal","volume":null,"pages":null},"PeriodicalIF":2.9,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141634169","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bilateral Femoral Arteritis Associated With Yersinia Enterocolitica in a 12-Year-old Girl. 一名 12 岁女孩的双侧股动脉炎与小肠结肠耶尔森菌有关
IF 2.9 4区 医学
Pediatric Infectious Disease Journal Pub Date : 2024-08-01 DOI: 10.1097/INF.0000000000004494
Tatsunori Fukai, Yuichi Kodama, Kohei Yamada, Naohiro Shiokawa, Toshiro Fukushige, Yuichi Nomura
{"title":"Bilateral Femoral Arteritis Associated With Yersinia Enterocolitica in a 12-Year-old Girl.","authors":"Tatsunori Fukai, Yuichi Kodama, Kohei Yamada, Naohiro Shiokawa, Toshiro Fukushige, Yuichi Nomura","doi":"10.1097/INF.0000000000004494","DOIUrl":"https://doi.org/10.1097/INF.0000000000004494","url":null,"abstract":"","PeriodicalId":19858,"journal":{"name":"Pediatric Infectious Disease Journal","volume":null,"pages":null},"PeriodicalIF":2.9,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141894036","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Maternal Risk Factors for Respiratory Syncytial Virus Lower Respiratory Tract Infection in Otherwise Healthy Preterm and Term Infants: A Systematic Review and Meta-analysis. 其他健康早产儿和足月儿呼吸道合胞病毒下呼吸道感染的母体风险因素:系统回顾与元分析》。
IF 2.9 4区 医学
Pediatric Infectious Disease Journal Pub Date : 2024-08-01 Epub Date: 2024-05-15 DOI: 10.1097/INF.0000000000004387
Paolo Manzoni, Elsa Viora, Marcello Lanari, Raffaella Iantomasi, Eva Agostina Montuori, Barry Rodgers-Gray, Nicola Waghorne, Bianca Masturzo
{"title":"Maternal Risk Factors for Respiratory Syncytial Virus Lower Respiratory Tract Infection in Otherwise Healthy Preterm and Term Infants: A Systematic Review and Meta-analysis.","authors":"Paolo Manzoni, Elsa Viora, Marcello Lanari, Raffaella Iantomasi, Eva Agostina Montuori, Barry Rodgers-Gray, Nicola Waghorne, Bianca Masturzo","doi":"10.1097/INF.0000000000004387","DOIUrl":"10.1097/INF.0000000000004387","url":null,"abstract":"<p><strong>Background/objective: </strong>To date, there is no published, formal assessment of all maternal risk factors for respiratory syncytial virus lower respiratory tract infection (RSV-LRTI) in infants. A systematic literature review and meta-analysis were undertaken to ascertain: What maternal risk factors are associated with an increased risk of RSV-LRTI in infants?</p><p><strong>Methods: </strong>The systematic literature review used explicit methods to identify, select and analyze relevant data. PubMed, Embase and the Cochrane Library were searched (November 2022) using terms regarding: (1) RSV/LRTI; (2) risk factors; (3) pregnant/postpartum population. Bayesian meta-analysis compared RSV hospitalization (RSVH) risk in infants born to mothers with or without certain risk factors.</p><p><strong>Results: </strong>A total of 2353 citations were assessed and 20 were included in the final review (10 individual studies; 10 pooled analyses). In 10 studies examining infants (<1 year) without comorbidities (primary outcome), 10 maternal risk factors were associated with RSV-LRTI/RSVH in multivariate analyses. Meta-analysis revealed smoking while pregnant increased infant RSVH risk by 2.01 (95% credible interval: 1.52-2.64) times, while breast-feeding was protective (0.73, 95% credible interval: 0.58-0.90). Risk scoring tools have reported that maternal risk factors contribute between 9% and 21% of an infant's total risk score for RSVH.</p><p><strong>Conclusions: </strong>A greater understanding of maternal risk factors and their relative contribution to infant RSV-LRTI will enable more accurate assessments of the impact of preventive strategies.</p>","PeriodicalId":19858,"journal":{"name":"Pediatric Infectious Disease Journal","volume":null,"pages":null},"PeriodicalIF":2.9,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140958245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Commentary: Academic Engagement With ChatGPT. 评论:与 ChatGPT 的学术互动。
IF 2.9 4区 医学
Pediatric Infectious Disease Journal Pub Date : 2024-08-01 Epub Date: 2024-04-30 DOI: 10.1097/INF.0000000000004384
Nigel Curtis, Ellie McDonald
{"title":"Commentary: Academic Engagement With ChatGPT.","authors":"Nigel Curtis, Ellie McDonald","doi":"10.1097/INF.0000000000004384","DOIUrl":"10.1097/INF.0000000000004384","url":null,"abstract":"","PeriodicalId":19858,"journal":{"name":"Pediatric Infectious Disease Journal","volume":null,"pages":null},"PeriodicalIF":2.9,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140865414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Insight Into Severe Neonatal COVID-19 Gained Through Whole Exome Sequencing of Twin Neonates. 通过对双胞胎新生儿进行全外显子组测序,深入了解严重新生儿 COVID-19。
IF 2.9 4区 医学
Pediatric Infectious Disease Journal Pub Date : 2024-07-31 DOI: 10.1097/INF.0000000000004501
Jennie Godwin, John Daniel, Susana Chavez-Bueno, Venkatesh Sampath
{"title":"Insight Into Severe Neonatal COVID-19 Gained Through Whole Exome Sequencing of Twin Neonates.","authors":"Jennie Godwin, John Daniel, Susana Chavez-Bueno, Venkatesh Sampath","doi":"10.1097/INF.0000000000004501","DOIUrl":"https://doi.org/10.1097/INF.0000000000004501","url":null,"abstract":"<p><p>The genetic basis of neonatal COVID-19 infection, which exhibits a range of severity, has not been investigated. We identified both shared and unique genetic variants involved in antiviral immune responses through whole exome sequencing of an infant who developed severe COVID-19 pneumonia and multisystem inflammatory syndrome and the twin brother also positive for severe acute respiratory syndrome-coronavirus-2, but with only moderate respiratory symptoms.</p>","PeriodicalId":19858,"journal":{"name":"Pediatric Infectious Disease Journal","volume":null,"pages":null},"PeriodicalIF":2.9,"publicationDate":"2024-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141856200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
New Insights Into Infections' Risk of Adolescents and Young Adults Treated for Acute Lymphoblastic Leukemia. 青少年和青年急性淋巴细胞白血病患者感染风险的新见解。
IF 2.9 4区 医学
Pediatric Infectious Disease Journal Pub Date : 2024-07-31 DOI: 10.1097/INF.0000000000004493
Camille Trimbour, Marie Balsat, Laura Olivier, Ana-Raluca Mihalcea, Nathalie Garnier, Kamila Kebaili, Nicolas Sirvent, Damien Dupont, Christine Fuhrmann, Alexandre Theron, Carine Domenech
{"title":"New Insights Into Infections' Risk of Adolescents and Young Adults Treated for Acute Lymphoblastic Leukemia.","authors":"Camille Trimbour, Marie Balsat, Laura Olivier, Ana-Raluca Mihalcea, Nathalie Garnier, Kamila Kebaili, Nicolas Sirvent, Damien Dupont, Christine Fuhrmann, Alexandre Theron, Carine Domenech","doi":"10.1097/INF.0000000000004493","DOIUrl":"https://doi.org/10.1097/INF.0000000000004493","url":null,"abstract":"<p><strong>Background: </strong>This study aims to compare the infections' risk between adolescents and young adults (AYAs), treated for acute lymphoblastic leukemia, and pediatric population. We also focused on their bacterial and fungal infection specificities.</p><p><strong>Methods: </strong>This case-control study investigated the occurrence of bacterial bloodstream infection (BSI) and proven and probable invasive fungal infection (IFI) in AYAs (15-25 years old) and children (1-14 years old) treated for acute lymphoblastic leukemia between January 2013 and December 2020 in 2 French tertiary pediatric and 2 referral adult hematological centers, independent of their treatment protocol. We also evaluated the impact of these infections on morbidity (necessity of intensive care) and mortality.</p><p><strong>Results: </strong>We analyzed 83 AYAs and 230 children and found that AYAs developed significantly more IFI than the pediatric population (22% vs. 10%, P = 0.007), regardless of their care center (adult or pediatric). Furthermore, the occurrence of BSI was similar between the 2 populations (48% vs. 51%, P = 0.66). Moreover, the occurrence of infection increased with the AYAs' risk group of treatment: standard, medium or high risk (P = 0.021 for BSI and P = 0.029 for IFI). Finally, the mortality rate is only 1.3% after a BSI whereas it increases to 4.9% after IFI.</p><p><strong>Conclusion: </strong>AYAs have their own specificity with an increased risk of fungal infection compared to children, independent of the care center. Antifungal prophylaxis should be contemplated, especially for patients classified in high-risk groups.</p>","PeriodicalId":19858,"journal":{"name":"Pediatric Infectious Disease Journal","volume":null,"pages":null},"PeriodicalIF":2.9,"publicationDate":"2024-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141856174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pneumonia With Empyema: A Rare Clinical Presentation of Bartonella henselae Infection in a 10-Year-Old Boy. 肺炎伴肺水肿:一名 10 岁男孩感染巴顿氏菌的罕见临床表现。
IF 2.9 4区 医学
Pediatric Infectious Disease Journal Pub Date : 2024-07-31 DOI: 10.1097/INF.0000000000004499
Iva Topalušić, Josip Pejić, Tonći Grmoja, Iva Butić, Ivan Pavić
{"title":"Pneumonia With Empyema: A Rare Clinical Presentation of Bartonella henselae Infection in a 10-Year-Old Boy.","authors":"Iva Topalušić, Josip Pejić, Tonći Grmoja, Iva Butić, Ivan Pavić","doi":"10.1097/INF.0000000000004499","DOIUrl":"https://doi.org/10.1097/INF.0000000000004499","url":null,"abstract":"<p><strong>Background: </strong>Cat-scratch disease is a common zoonosis in children. However, atypical clinical presentation of cat-scratch disease is less common, and lung involvement is particularly rare. The usual presentation of lung disease in bartonellosis includes other organ involvement and is more common in immunocompromised patients.</p><p><strong>Case report: </strong>We present a 10-year-old immunocompetent patient with pneumonia and inoculated empyema caused by Bartonella henselae, without any other organ involvement, which occurred 2 weeks after lymphadenopathy. The definite diagnosis was established using the polymerase chain reaction of the empyema obtained from thoracocentesis. The boy was treated with several antibiotics (ceftriaxone, azithromycin, amoxicillin with clavulanic acid, meropenem and vancomycin) and completely recovered after the 3-month follow-up period.</p><p><strong>Conclusions: </strong>This is a unique case of the difficult-to-treat pneumonia with inoculated empyema, caused by B. henselae, in an immunocompetent child, without any other organ involvement. The clinical course was favorable. A high level of clinical suspicion is mandatory for the diagnosis.</p>","PeriodicalId":19858,"journal":{"name":"Pediatric Infectious Disease Journal","volume":null,"pages":null},"PeriodicalIF":2.9,"publicationDate":"2024-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141856175","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Delayed Induction of Noninflammatory SARS-CoV-2 Spike-Specific IgG4 Antibodies Detected 1 Year After BNT162b2 Vaccination in Children. 儿童接种 BNT162b2 疫苗 1 年后检测到非炎症性 SARS-CoV-2 穗状特异性 IgG4 抗体的延迟诱导。
IF 2.9 4区 医学
Pediatric Infectious Disease Journal Pub Date : 2024-07-30 DOI: 10.1097/INF.0000000000004488
Robin Kobbe, Cornelius Rau, Ulf Schulze-Sturm, Felix Stahl, Luis Fonseca-Brito, Anke Diemert, Marc Lütgehetmann, Marylyn M Addo, Petra Arck, Leonie M Weskamm
{"title":"Delayed Induction of Noninflammatory SARS-CoV-2 Spike-Specific IgG4 Antibodies Detected 1 Year After BNT162b2 Vaccination in Children.","authors":"Robin Kobbe, Cornelius Rau, Ulf Schulze-Sturm, Felix Stahl, Luis Fonseca-Brito, Anke Diemert, Marc Lütgehetmann, Marylyn M Addo, Petra Arck, Leonie M Weskamm","doi":"10.1097/INF.0000000000004488","DOIUrl":"https://doi.org/10.1097/INF.0000000000004488","url":null,"abstract":"<p><p>Humoral immune responses after BNT162b2 vaccination are predominantly composed of immunoglobulin (Ig) G1 and IgG3 subclass antibodies. As previously described in adults, S1-specific and receptor-binding domain-specific IgG4 levels increase significantly 1 year after the second BNT162b2 vaccination in children 5-11 years of age. Understanding mRNA vaccine-specific IgG4 responses in all age groups is crucial as more mRNA vaccines will reach licensure in the coming years.</p>","PeriodicalId":19858,"journal":{"name":"Pediatric Infectious Disease Journal","volume":null,"pages":null},"PeriodicalIF":2.9,"publicationDate":"2024-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141793039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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