Pediatric Infectious Disease Journal最新文献_第10页

Prevalence and Predictors of Tuberculosis Infection in Children and Adolescents in Rural Uganda: A Cross-sectional Study. 乌干达农村地区儿童和青少年结核病感染的流行率和预测因素：横断面研究。

IF 2.9 4区医学

Pediatric Infectious Disease Journal Pub Date : 2024-07-15 DOI: 10.1097/INF.0000000000004475

Elijah Kakande, Bob Ssekyanzi, Rachel Abbott, Willington Ariho, Gloria Nattabi, Kirsten Landsiedel, Jennifer Temple, Gabriel Chamie, Diane V Havlir, Moses R Kamya, Edwin D Charlebois, Laura B Balzer, Carina Marquez

{"title":"Prevalence and Predictors of Tuberculosis Infection in Children and Adolescents in Rural Uganda: A Cross-sectional Study.","authors":"Elijah Kakande, Bob Ssekyanzi, Rachel Abbott, Willington Ariho, Gloria Nattabi, Kirsten Landsiedel, Jennifer Temple, Gabriel Chamie, Diane V Havlir, Moses R Kamya, Edwin D Charlebois, Laura B Balzer, Carina Marquez","doi":"10.1097/INF.0000000000004475","DOIUrl":"https://doi.org/10.1097/INF.0000000000004475","url":null,"abstract":"Background: Much of the latent tuberculosis (TB) reservoir is established in childhood and adolescence. Yet, age-specific data on prevalence and predictors of infection in this population are sparse and needed to guide prevention and case finding.Methods: From December 2021 to June 2023, we measured TB infection in children 1-17 years in 25 villages in rural Southwestern Uganda. We defined TB infection as a positive QuantiFERON Gold Plus Test (QFT). We estimated overall and age-stratified population-level prevalence and adjusted risk ratios (aRR) of TB infection for individual, household, and community-based predictors, accounting for age, TB contact, and clustering by household.Results: Estimated TB infection prevalence was 9.6% [95% confidence interval (CI): 8.7-10.5%] among the 5789 participants, and prevalence varied slightly with age. Household-level risk factors included crowding (aRR: 1.25, 95% CI: 1.03-1.53), indoor cooking (aRR: 1.62, 95% CI: 1.14-2.30), living with ≥2 persons who drink alcohol (aRR: 1.47, 95% CI: 1.04-2.07). The predominant community-based risk factor was child mobility (aRR: 1.67, 95% CI: 1.24-2.26). In age-stratified analyses, household predictors were important in early childhood but not adolescence, where mobility was predominant (aRR: 1.66, 95% CI: 1.13-2.44).Conclusion: We detected a high prevalence of TB infection in children and adolescents in rural Uganda. On a population level, TB risk factors change throughout the early life course, with child mobility a key risk factor in adolescence. Age-specific TB case finding and prevention strategies that address both household and extra-household risk factors are needed to address TB transmission.","PeriodicalId":19858,"journal":{"name":"Pediatric Infectious Disease Journal","volume":null,"pages":null},"PeriodicalIF":2.9,"publicationDate":"2024-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141634167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Primary Cutaneous Mucormycosis Confirmed by Molecular Testing in a Child With Acute Lymphoblastic Leukemia on Daily Imatinib. 一名每天服用伊马替尼的急性淋巴细胞白血病患儿通过分子检测确诊的原发性皮肤黏液瘤病

IF 2.9 4区医学

Pediatric Infectious Disease Journal Pub Date : 2024-07-15 DOI: 10.1097/INF.0000000000004473

Yaseen Rafee, Nesma Ghanim, Maen Kamal, Wad Elsheikh, Mohammed Al Nahar, Nkechi Onwuzurike, Allison Schnepp

引用次数: 0

First Evidence of Streptococcus pyogenes M1UK Clone in Pediatric Invasive Infections in Italy by Molecular Surveillance. 通过分子监测首次发现意大利小儿侵袭性感染中的化脓性链球菌 M1UK 克隆。

IF 2.9 4区医学

Pediatric Infectious Disease Journal Pub Date : 2024-07-12 DOI: 10.1097/INF.0000000000004455

Gianluca Vrenna, Martina Rossitto, Marilena Agosta, Venere Cortazzo, Valeria Fox, Maia De Luca, Laura Lancella, Livia Gargiullo, Annarita Granaglia, Vanessa Fini, Katia Yu La Rosa, Marta Argentieri, Laura Pansani, Annamaria Sisto, Massimiliano Raponi, Alberto Villani, Carlo Federico Perno, Paola Bernaschi

引用次数: 0

A Preterm Baby With Ascites Related to Congenital CMV Infection. 早产儿腹水与先天性巨细胞病毒感染有关。

IF 2.9 4区医学

Pediatric Infectious Disease Journal Pub Date : 2024-07-12 DOI: 10.1097/INF.0000000000004465

Yusriya Al Rawahi, Jasim Al-Khamyasi, Hilal Al Mandhari, Zaid Al Hinai, Majid Albusaidi, Laila Al Yazidi

引用次数: 0

Shiga Toxin-Producing Escherichia coli 0157:H7 Illness Outbreak Associated With Untreated, Pressurized, Municipal Irrigation Water—Utah, 2023 2023 年与未经处理的加压市政灌溉用水有关的产志贺毒素大肠埃希氏菌 0157:H7 疾病暴发--犹他州

IF 2.9 4区医学

Pediatric Infectious Disease Journal Pub Date : 2024-07-10 DOI: 10.1097/inf.0000000000004428

引用次数: 0

Bone and Joint Infections in Children With Sickle Cell Disease in French Guiana: A 13-year Retrospective Multicenter Review. 法属圭亚那镰状细胞病患儿的骨与关节感染：13年回顾性多中心研究。

IF 2.9 4区医学

Pediatric Infectious Disease Journal Pub Date : 2024-07-09 DOI: 10.1097/INF.0000000000004416

Apolline Furgier, Juliette Goutines, Succes Dobian, Magaly Zappa, Magalie Demar, Nadjia Aigoun, Bruno Oubda, Albert Faye, Narcisse Elenga, Lindsay Osei

{"title":"Bone and Joint Infections in Children With Sickle Cell Disease in French Guiana: A 13-year Retrospective Multicenter Review.","authors":"Apolline Furgier, Juliette Goutines, Succes Dobian, Magaly Zappa, Magalie Demar, Nadjia Aigoun, Bruno Oubda, Albert Faye, Narcisse Elenga, Lindsay Osei","doi":"10.1097/INF.0000000000004416","DOIUrl":"https://doi.org/10.1097/INF.0000000000004416","url":null,"abstract":"Introduction: Sickle cell disease (SCD) is a genetic disorder with a high infectious morbidity and mortality and a heterogeneous distribution in France. One of the challenges is to differentiate a bone and joint infection (BJI) from a vaso-occlusive crisis. This challenge is particularly prevalent in French Guiana, an overseas territory with the highest incidence of SCD in France. The aim of this study was to describe the epidemiology of BJI in children with SCD in French Guiana.Method: This was a retrospective multicentric descriptive study of SCD patients living in French Guiana aged under 18 and diagnosed with a BJI between 2010 and 2022. These BJI were divided into 2 groups: those with microbiological documentation (d-BJI) and those without microbiological identification (ud-BJI).Results: A total of 53 episodes of BJI in 42 patients (mean age 7.2 years) were reported. Clinical symptoms on arrival were comparable between the d-BJI and ud-BJI groups. Patients in the d-BJI group had longer average hospital stays (40.4 days vs. 16.8 days, P = 0.01) and Salmonella spp. were the most identified bacteria (n = 8/13). White blood cell count was greater in the d-BJI group (30.3 G/L vs. 18.G/L, P = 0.01) and a collection was more frequently identified on imaging (11/13 vs. 16/40, P = 0.01) in this group. Initial in-hospital antibiotic therapy was longer in the d-BJI group (17.2 days vs. 12.8, P = 0.02), as were infection-related complications (9/13 vs. 12/40 P = 0.01).Conclusion: BJI in children with SCD is not sufficiently microbiologically documented. Progress must be made to improve the documentation of BJI.","PeriodicalId":19858,"journal":{"name":"Pediatric Infectious Disease Journal","volume":null,"pages":null},"PeriodicalIF":2.9,"publicationDate":"2024-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141580464","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Lock Therapy for Treatment and Prevention of Catheter-Related Infections. 用于治疗和预防导管相关感染的锁定疗法。

IF 2.9 4区医学

Pediatric Infectious Disease Journal Pub Date : 2024-07-08 DOI: 10.1097/INF.0000000000004457

Adriana Shan, Mar Santos-Sebastián, Jesús Saavedra-Lozano

引用次数: 0

Acute Focal Bacterial Nephritis without Pyuria: A Peculiar Subtype of Urinary Tract Infection. 无脓尿的急性灶性细菌性肾炎：尿路感染的一种特殊亚型

IF 2.9 4区医学

Pediatric Infectious Disease Journal Pub Date : 2024-07-05 DOI: 10.1097/INF.0000000000004469

Juan Tu, Tiantian Lin, Huarong Li, Chaoying Chen

引用次数: 0

Emerging and Re-Emerging Enterovirus Infections: The Known Unknowns. 新发和再发肠病毒感染：已知的未知数。

IF 2.9 4区医学

Pediatric Infectious Disease Journal Pub Date : 2024-07-05 DOI: 10.1097/INF.0000000000004472

Simon Cottrell, Catherine Moore

引用次数: 0

Respiratory Syncytial Virus Hospital Admission Rates and Patients' Characteristics Before the Age of 2 Years in England, 2015-2019. 2015-2019 年英格兰两岁前呼吸道合胞病毒入院率和患者特征。

IF 2.9 4区医学

Pediatric Infectious Disease Journal Pub Date : 2024-07-05 DOI: 10.1097/INF.0000000000004467

Maria João Fonseca, Saskia Hagenaars, Mathieu Bangert, Clare Flach, Richard D A Hudson

{"title":"Respiratory Syncytial Virus Hospital Admission Rates and Patients' Characteristics Before the Age of 2 Years in England, 2015-2019.","authors":"Maria João Fonseca, Saskia Hagenaars, Mathieu Bangert, Clare Flach, Richard D A Hudson","doi":"10.1097/INF.0000000000004467","DOIUrl":"10.1097/INF.0000000000004467","url":null,"abstract":"Background: A granular understanding of respiratory syncytial virus (RSV) burden in England is needed to prepare for new RSV prevention strategies. We estimated the rates of RSV hospital admissions before the age of 2 years in England and described baseline characteristics.Methods: A birth cohort of all infants born between March 1, 2015, and February 28, 2017 (n = 449,591) was established using Clinical Practice Research Datalink-Hospital Episode Statistics. Case cohorts included infants with admission for (1) RSV, (2) bronchiolitis, (3) any respiratory tract infection (RTI) <24 months and (4) RSV predicted by an algorithm <12 months. Baseline characteristics were described in the case and comparative cohorts (infants without corresponding admission). Cumulative incidence and admission rates were calculated. Multiple linear regression was used to estimate the proportion of RTI healthcare visits attributable to RSV.Results: The RSV-coded/RSV-predicted case cohorts were composed of 4813/12,694 infants (cumulative incidence: 1.1%/2.8%). Case cohort infants were more likely to have low birth weight, comorbidities and to be born during RSV season than comparative cohort infants, yet >77% were term-healthy infants and >54% were born before the RSV season. During the first year of life, 11.6 RSV-coded and 34.4 RSV-predicted hospitalizations occurred per 1000 person-years. Overall, >25% of unspecified lower RTI admissions were estimated to be due to RSV.Conclusions: In England, 1 in 91 infants had an RSV-coded admission, likely underestimated by ~3-fold. Most infants were term-healthy infants born before the RSV season. To decrease the total burden of RSV at the population level, immunization programs need to protect all infants.","PeriodicalId":19858,"journal":{"name":"Pediatric Infectious Disease Journal","volume":null,"pages":null},"PeriodicalIF":2.9,"publicationDate":"2024-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11319075/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141580506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0