Simonetta Costa, Simona Fattore, Cecilia Brughitta, Paola Catalano, Nicola Frattaruolo, Liliana Sollazzi, Marco Rossi, Paola Aceto, Filomena Valentina Paradiso, Lorenzo Nanni, Giovanni Vento
{"title":"Advantage of bedside versus conventional operating room surgery in the management of term and preterm newborn infants: a single center retrospective observational study.","authors":"Simonetta Costa, Simona Fattore, Cecilia Brughitta, Paola Catalano, Nicola Frattaruolo, Liliana Sollazzi, Marco Rossi, Paola Aceto, Filomena Valentina Paradiso, Lorenzo Nanni, Giovanni Vento","doi":"10.1007/s00383-024-05937-0","DOIUrl":"10.1007/s00383-024-05937-0","url":null,"abstract":"<p><strong>Purpose: </strong>To compare postoperative outcomes of bedside surgery (BS) with those of surgery performed in the operating room (ORS) in preterm and full-term neonates.</p><p><strong>Methods: </strong>Data from neonates undergoing major surgical interventions were retrospectively evaluated. Primary outcome was the incidence of postoperative hypothermia. Secondary outcomes were the mortality rate within 30 days of surgery and the occurrence of post-operative infection within 48 h of surgery.</p><p><strong>Results: </strong>374 interventions performed on 222 neonates were analysed: 55 interventions on 47 neonates in the BS group and 319 interventions on 175 neonates in the ORS group. Compared to the ORS group, infants in the BS group had lower gestational age (GA) and birthweight, higher incidence of morbidity and mortality at discharge. No difference was found in the incidence of postoperative hypothermia and infections within 48 h of surgery, while mortality within 30 days of surgery was higher in the BS group. To multivariable logistic regression analysis, weight at the time of surgery [OR (IC 95%) 0.711 (0.542-0.931); p 0.013] and emergency/urgency modality [OR (IC 95%) 1.934 (1.221-3.063); p 0.005] were identified as variables associated with the risk of hypothermia, while GA [OR (IC 95%) 0.830 (0.749-0.920); p 0.000] and need for pre-surgery inotropes [OR (IC 95%) 8.221 (2.128-31.760); p 0.002] were associated with mortality within 30 days of surgery.</p><p><strong>Conclusions: </strong>BS resulted safe and effective in not increasing the risk of postoperative adverse events despite being performed in worse clinical conditions than ORS.</p>","PeriodicalId":19832,"journal":{"name":"Pediatric Surgery International","volume":"41 1","pages":"57"},"PeriodicalIF":1.5,"publicationDate":"2025-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11698754/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142922401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effect of hand massage after abdominal surgery on pain, emotional symptoms and physiological parameters among children.","authors":"Sevim Çimke, Meral Bayat","doi":"10.1007/s00383-024-05954-z","DOIUrl":"10.1007/s00383-024-05954-z","url":null,"abstract":"<p><strong>Aim: </strong>This randomized controlled study aimed to evaluate the effect of hand massage on pain, emotional symptoms, and physiological parameters in children after abdominal surgery.</p><p><strong>Materials and methods: </strong>The study included 40 children aged 7-12 years who underwent abdominal surgery (20 intervention, 20 control). Data were collected using the Faces Pain Scale-Revised, Children's Emotion Manifestation Scale, Physiological Measurements Chart, and Child Information Form. The intervention group received a 10-min hand massage 3 h after surgery, and measurements were taken before the massage, immediately after the massage, and 30 min after the massage. Statistical analyses were performed using the Mann-Whitney U, Friedman, and Bonferroni tests.</p><p><strong>Results: </strong>Immediately after the massage, the pain and emotional manifestation scores were significantly lower in the intervention group compared to the control group (p < 0.05). However, no significant difference was found between the two groups at the third measurement (p = 0.478). Heart rate significantly decreased in the intervention group immediately after the massage (p < 0.001), while it significantly increased in the control group (p < 0.001).</p>","PeriodicalId":19832,"journal":{"name":"Pediatric Surgery International","volume":"41 1","pages":"55"},"PeriodicalIF":1.5,"publicationDate":"2025-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142922447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"How many cases do young pediatric surgeons need to experience to achieve autonomy in performing pediatric endoscopic surgery? A nationwide survey to establish an ideal curriculum for pediatric endoscopic surgery in Japan.","authors":"Masakazu Murakami, Yo Kurashima, Katsuhiro Ogawa, Shinichiro Yokoyama, Satoshi Obata, Go Miyano, Tetsuya Ishimaru, Hiroshi Kawashima, Hiroo Uchida, Tatsuro Tajiri, Atsuyuki Yamataka, Hiroomi Okuyama, Satoshi Ieiri","doi":"10.1007/s00383-024-05958-9","DOIUrl":"https://doi.org/10.1007/s00383-024-05958-9","url":null,"abstract":"<p><strong>Purpose: </strong>To ensure the safe prevalence of pediatric endoscopic surgery in Japan, a training curriculum should be established. In addition, the number of pediatric surgical cases is decreasing due to the decreasing birth rate in Japan, and it is necessary to clarify the number of surgical cases required for young pediatric surgeons to achieve autonomy in pediatric endoscopic surgery.</p><p><strong>Methods: </strong>An online nationwide survey was conducted among young pediatric surgeons with 3-15 years of clinical experience in Japan. We assessed training experience, opinions concerning the ideal training curriculum, and the correlation between surgical experience and the level of autonomy for pediatric endoscopic surgeries.</p><p><strong>Results: </strong>One hundred seventy participants responded to the survey (response rate: 35.2%). Only 18% answered that their training facility had a regular educational off-the-job training program. Ninety percent of respondents answered that an educational curriculum for pediatric endoscopic surgery was necessary. It took 11-20 cases to achieve autonomy in laparoscopic appendectomy and laparoscopic inguinal hernia repair.</p><p><strong>Conclusion: </strong>This survey revealed that off-the-job training programs were insufficient. The results of this study are expected to aid in the establishment of an effective curriculum for pediatric endoscopic surgery in the era of declining birth rates.</p>","PeriodicalId":19832,"journal":{"name":"Pediatric Surgery International","volume":"41 1","pages":"54"},"PeriodicalIF":1.5,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142909888","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Palak Singhai, Shailesh Solanki, Ravi P Kanojia, Nitin James Peters, Chimmani Sai Kiran, Pramod Kumar Gupta, Sadhna B Lal, Jai Kumar Mahajan
{"title":"Impact of socioeconomic and geographical factors on clinical care of biliary atresia patients: a cross-sectional study.","authors":"Palak Singhai, Shailesh Solanki, Ravi P Kanojia, Nitin James Peters, Chimmani Sai Kiran, Pramod Kumar Gupta, Sadhna B Lal, Jai Kumar Mahajan","doi":"10.1007/s00383-024-05949-w","DOIUrl":"10.1007/s00383-024-05949-w","url":null,"abstract":"<p><strong>Purpose: </strong>Biliary atresia (BA) is a critical pediatric condition requiring timely intervention through Kasai portoenterostomy (KPE), and up to two-thirds of patients need liver transplantation (LT). The outcomes for BA patients still need improvement in low- and middle-income countries. This study aims to assess the socioeconomic and geographical profile of BA patients in India, focusing on their compliance with follow-up care, treatment-seeking behaviour, and acceptability of LT in addition, it provides recommendations to overcome identified challenges.</p><p><strong>Methods: </strong>A retrospective observational study was conducted in a tertiary care centre in India, including 48 patients who underwent KPE between 2018 and 2022. SES was assessed using the modified Kuppuswamy scale, and geographical areas were classified as per the criteria of the Indian Census 2011. Compliance with follow-up, treatment-seeking behaviour, and LT acceptability were evaluated.</p><p><strong>Results: </strong>The majority of patients belonged to rural areas and lower middle SES. Compliance with follow-up decreased over time, with financial and geographical barriers being significant challenges. Only one patient underwent LT due to prohibitive costs and limited accessibility.</p><p><strong>Conclusion: </strong>Socioeconomic and geographical factors significantly impact the clinical outcomes of BA patients in India. Improving education, healthcare infrastructure, and financial support is crucial for enhancing patient compliance and access to necessary treatments.</p>","PeriodicalId":19832,"journal":{"name":"Pediatric Surgery International","volume":"41 1","pages":"53"},"PeriodicalIF":1.5,"publicationDate":"2024-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142909901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Reut Kassif Lerner, Amit Gibori, Evyatar Hubara, Tal Sadeh, Marina Rubinstein, Gidi Paret, Itai M Pessach
{"title":"Factors affecting intensive care length of stay in critically ill pediatric patients with burn injuries.","authors":"Reut Kassif Lerner, Amit Gibori, Evyatar Hubara, Tal Sadeh, Marina Rubinstein, Gidi Paret, Itai M Pessach","doi":"10.1007/s00383-024-05945-0","DOIUrl":"https://doi.org/10.1007/s00383-024-05945-0","url":null,"abstract":"<p><strong>Background: </strong>Burns in children are often complex injuries, leading to prolonged length of stay (LOS) and significant morbidity. LOS in pediatric intensive care units (PICUs) is a key measure for evaluating illness severity, clinical outcomes, and quality of care. Accurate prediction of LOS is vital for improving care planning and resource allocation. There is limited data for predicting LOS in severely burned children in PICU. This study aims to identify significant factors associated with prolonged PICU stays and offer a simple LOS-predicting model.</p><p><strong>Methods: </strong>This historical cohort study included all patients < 18 years, admitted for severe burn injuries to Israel's largest tertiary hospital PICU, from 2015 to 2020. Statistical analyses were conducted to identify factors linked to prolonged LOS and a predictive model was designed.</p><p><strong>Results: </strong>The study included 39 pediatric burn patients and identified several factors associated with longer PICU stays. Patients with LOS of ˃7 days (i.e.-\"long LOS\") had significantly higher %TBSA (33.11 ± 17.87% vs. 16.67 ± 7.98%, p < 0.001. During the first 24 and 48 h, the \"long LOS\" group had lower minimal systolic blood pressure (SBP) (70.67 ± 17.49 mmHg vs. 84.38 ± 16.73 mmHg, p = 0.015 and 69.39 mmHg ± 16.44 vs. 81.10 mmHg ± 19.67, p = 0.018). Although serum lactate levels were higher in the \"long LOS\" group, the difference was not significant, and platelet counts in this group were significantly lower during the first 48 h (184 K/µL vs. 264.5 K/µL, p = 0.003). A predictive model based on %TBSA, SBP, lactate, and platelet count was developed, demonstrating 100% specificity and positive predictive value for predicting LOS over 7 days in severely burned children.</p><p><strong>Conclusions: </strong>Key clinical indicators at PICU admission in severely burned children were associated with LOS > 7 days. The resulting predictive model, although requiring further validation in multi-site studies, offers a promising tool for enhancing care planning in this population.</p>","PeriodicalId":19832,"journal":{"name":"Pediatric Surgery International","volume":"41 1","pages":"51"},"PeriodicalIF":1.5,"publicationDate":"2024-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142896571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hai Choon Soh, Shireen Anne Nah, Wei Sheng Tan, Srihari Singaravel, Yew-Wei Tan, Seet Fai Woon, Bathmavathy Chandran, Anand Sanmugam
{"title":"Antenatal detection of pediatric surgical congenital abnormalities and its effect on maternal anxiety: a multicentre prospective study in a middle-income country.","authors":"Hai Choon Soh, Shireen Anne Nah, Wei Sheng Tan, Srihari Singaravel, Yew-Wei Tan, Seet Fai Woon, Bathmavathy Chandran, Anand Sanmugam","doi":"10.1007/s00383-024-05952-1","DOIUrl":"10.1007/s00383-024-05952-1","url":null,"abstract":"<p><strong>Background: </strong>In middle-income countries, healthcare systems face unique challenges in ensuring timely antenatal detection of congenital abnormalities that require pediatric surgical intervention. Early detection can significantly improve outcomes, yet resource constraints often limit access to diagnostic technologies. This study evaluates the antenatal detection rate of congenital abnormalities referred to pediatric surgical services in three Malaysian tertiary centers and examines its effect on maternal anxiety.</p><p><strong>Methods: </strong>A prospective observational study was conducted at Hospital Raja Permaisuri Bainun (HRPB), Hospital Sultanah Aminah (HSA), and University of Malaya Medical Centre (UMMC) over a 8 month period. Data were collected from mothers of neonates born with congenital abnormalities, and the Spielberg State-Trait Anxiety Inventory (STAI) was used to assess maternal anxiety.</p><p><strong>Results: </strong>A total of 58 patients were recruited. The overall antenatal detection rate for congenital abnormalities was 43.1%, comparable to high-income countries despite resource limitations. Antenatal counselling by pediatric surgeons was rare (6.9%) and showed no significant reduction in maternal anxiety (p = 0.374).</p><p><strong>Conclusion: </strong>The antenatal detection rates at the three Malaysian centers align with those in more developed nations, underscoring the potential of middle-income healthcare systems to deliver high-quality prenatal care. However, improving access to diagnostic technologies and involving pediatric surgical teams in antenatal counselling could further enhance care.</p>","PeriodicalId":19832,"journal":{"name":"Pediatric Surgery International","volume":"41 1","pages":"52"},"PeriodicalIF":1.5,"publicationDate":"2024-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142896552","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Miguel Couselo, Vicente Ibáñez, Beatriz Pemartín, Rosa Fonseca, Juan José Vila
{"title":"Diagnostic value of hemoglobin concentration in identifying Meckel's diverticulum in pediatric lower gastrointestinal bleeding.","authors":"Miguel Couselo, Vicente Ibáñez, Beatriz Pemartín, Rosa Fonseca, Juan José Vila","doi":"10.1007/s00383-024-05944-1","DOIUrl":"https://doi.org/10.1007/s00383-024-05944-1","url":null,"abstract":"<p><strong>Purpose: </strong>To assess the diagnostic performance of hemoglobin concentration for Meckel's diverticulum (MD) and evaluate if hemoglobin levels could be useful in the surgical decision-making process of children with lower gastrointestinal bleeding (LGIB).</p><p><strong>Methods: </strong>Retrospective cohort study of children with LGIB attending the emergency department between 2011 and 2021. Episodes of LGIB were divided into two groups: MeckD (MD diagnosed by surgery) and non-MeckD. Demographic and clinical variables were recorded. Comparisons between groups were made using the χ2 and the Mann-Whitney U tests. The diagnostic performance of hemoglobin for MD was studied using ROC curves.</p><p><strong>Results: </strong>Eight hundred and nineteen episodes of LGIB were considered. Blood samples were obtained in 233 cases (31 with MD). There were differences between MeckD and non-MeckD in hemoglobin concentration (8.7 vs. 12.6; U = 592; p < 0.01), hematochezia (83.9% vs. 50.5%; χ2 = 12.1; p < 0.01), absence of other symptoms (61.3% vs. 39.6%; χ2 = 5.2; p < 0.02) and blood transfusions (41.9% vs. 9.9%; χ2 = 74.8; p < 0.01). Hemoglobin levels ≤ 8.3 g/dL obtained a specificity ≥ 99.01% and a positive likelihood ratio ≥ 35.8 for MD. The area under the curve was 0.91 (95% CI 0.86-0.94).</p><p><strong>Conclusion: </strong>Hemoglobin showed a good diagnostic performance for MD. Low hemoglobin levels could guide surgical indications in the management of children with LGIB.</p>","PeriodicalId":19832,"journal":{"name":"Pediatric Surgery International","volume":"41 1","pages":"50"},"PeriodicalIF":1.5,"publicationDate":"2024-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142896559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Henrik Røkkum, Martin Alavi Treider, Wenche Bakken Børke, Janicke Bergersen, Kristoffer Lassen, Ragnhild Støen, Thorstein Sæter, Kristin Bjørnland
{"title":"Enhanced recovery protocol for congenital duodenal obstruction - initial experiences with development and implementation.","authors":"Henrik Røkkum, Martin Alavi Treider, Wenche Bakken Børke, Janicke Bergersen, Kristoffer Lassen, Ragnhild Støen, Thorstein Sæter, Kristin Bjørnland","doi":"10.1007/s00383-024-05951-2","DOIUrl":"10.1007/s00383-024-05951-2","url":null,"abstract":"<p><strong>Background: </strong>The experience with Enhanced Recovery After Surgery<sup>®</sup> (ERAS<sup>®</sup>) protocols in neonatal intestinal surgery is very limited. We present the development and implementation of an Enhanced Recovery Protocol (ERP) designed specifically for neonates treated for congenital duodenal obstruction (CDO), and early outcome after implementation.</p><p><strong>Methods: </strong>An ERP for CDO was developed and implemented. Experiences with ERP development and implementation are described. Early clinical outcome in patients treated before (January 2015-Descember 2020) and after (February 2022-September 2024) implementation were compared. Ethical approval was obtained.</p><p><strong>Results: </strong>A multidisciplinary ERP team was established. The ERP for CDO was developed with stakeholder involvement. Implementation was challenging, but with close follow-up and frequent meetings with the involved medical disciplines, an overall ERP compliance of 80% was achieved for the 21 patients treated after implementation. Compared to 40 patients treated before ERP implementation (January 2015-Descember 2020), the use of minimally invasive surgery increased and time to first postoperative enteral and breast feed were reduced, without increasing the rate of postoperative complications.</p><p><strong>Conclusions: </strong>This study presents an ERP specifically designed for CDO with a unique description of our experiences with the development and implementation process. Early results suggest that this ERP for CDO is feasible and safe.</p>","PeriodicalId":19832,"journal":{"name":"Pediatric Surgery International","volume":"41 1","pages":"49"},"PeriodicalIF":1.5,"publicationDate":"2024-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11680611/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142896566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Impact of the relationship between renal pedicles and tumors on surgical outcomes for non-high-risk abdominal neuroblastoma.","authors":"Yuki Yamamoto, Akihiro Yoneda, Osamu Miyazaki, Kimikazu Matsumoto, Satoko Yamagishi, Akinori Ichinose, Tomoya Hirokawa, Michimasa Fujiogi, Tetsuya Ishimaru, Naoki Shimojima","doi":"10.1007/s00383-024-05956-x","DOIUrl":"https://doi.org/10.1007/s00383-024-05956-x","url":null,"abstract":"<p><strong>Purpose: </strong>To assess the impact of the relationship between renal pedicles and tumors on surgical outcomes in patients with non-high-risk abdominal neuroblastoma.</p><p><strong>Methods: </strong>We retrospectively analyzed cases of neuroblastoma without metastasis treated at our hospital between March 2002 and December 2023. Cases in which surgical resection was performed were divided into three groups according to imaging findings at the time of diagnosis and before surgery: Group E (tumor encasing renal pedicles), Group C (tumor in contact with renal pedicles), and Group S (tumor separated from renal pedicles).</p><p><strong>Results: </strong>Among 256 neuroblastoma cases diagnosed during the study period, 27 non-high-risk cases that underwent surgery for partial abdominal tumor resection or greater were included. The numbers of cases in the S group, C group, and E group, respectively, were 7, 9, and 11 at diagnosis, and 8, 14, and 5 before surgery. Renal complications (combined concurrent renal resection and post-operative renal atrophy) were seen in five E group cases at the time of diagnosis, and two C group cases and three E group cases preoperatively.</p><p><strong>Conclusion: </strong>In non-high-risk abdominal neuroblastomas, tumors encased in the renal pedicles have the highest risk of renal complications, followed by tumors in contact with the renal pedicles.</p>","PeriodicalId":19832,"journal":{"name":"Pediatric Surgery International","volume":"41 1","pages":"47"},"PeriodicalIF":1.5,"publicationDate":"2024-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142896586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
N Mokhaberi, E P Schneider, M Aftzoglou, I Hüners, M Körner, L Armbrust, D Biermann, R Kozlik-Feldmann, M Hübler, K Reinshagen, C Tomuschat
{"title":"Risk factors and surgical outcomes in pediatric patients with congenital heart disease and ischemic colitis.","authors":"N Mokhaberi, E P Schneider, M Aftzoglou, I Hüners, M Körner, L Armbrust, D Biermann, R Kozlik-Feldmann, M Hübler, K Reinshagen, C Tomuschat","doi":"10.1007/s00383-024-05950-3","DOIUrl":"10.1007/s00383-024-05950-3","url":null,"abstract":"<p><strong>Introduction: </strong>This study investigates risk factors and surgical outcomes in pediatric patients with congenital heart defects (CHD) who develop ischemic colitis (IC). Previous research indicates a higher IC risk in very low birth weight neonates with CHD.</p><p><strong>Methods: </strong>A retrospective analysis compared an IC-CHD group to a CHD-only group. Key variables included gestational age, birth weight, multiple pregnancies, prematurity, APGAR scores, cardiac and surgical characteristics, Aristotle-Score, and mortality rates. Surgical outcomes such as bowel resection and stoma procedures were also evaluated.</p><p><strong>Results: </strong>IC-CHD exhibited significantly lower gestational ages and birth weights, with higher rates of multiple pregnancies and prematurity. APGAR scores were notably lower. Cardiac and surgical data showed more frequent ECMO use and shorter cardiopulmonary bypass durations in the IC-CHD group. High rates of bowel resection highlighted severe gastrointestinal involvement. Mortality was significantly higher in IC-CHD with elevated Aristotle scores correlating with poorer outcomes.</p><p><strong>Conclusion: </strong>Gestational age, birth weight, and initial health status are critical in predicting IC risk and surgical outcomes in pediatric patients with CHD. The significantly higher mortality and complex surgical needs in the IC-CHD group underscore the necessity for vigilant monitoring and tailored interventions. Development of targeted therapeutic strategies adjustment for confounding factors in future studies is needed.</p>","PeriodicalId":19832,"journal":{"name":"Pediatric Surgery International","volume":"41 1","pages":"48"},"PeriodicalIF":1.5,"publicationDate":"2024-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11671421/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142896600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}