{"title":"Introduction to the special issue on cognitive neurosurgery","authors":"Adrià Rofes, Vitória Piai","doi":"10.1111/jnp.12358","DOIUrl":"10.1111/jnp.12358","url":null,"abstract":"","PeriodicalId":197,"journal":{"name":"Journal of Neuropsychology","volume":"18 S1","pages":"1-6"},"PeriodicalIF":1.8,"publicationDate":"2024-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139904580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jordan Holmén, William Chaplin, Tamara Del Vecchio
{"title":"Measures of executive function may not be indicators of latent constructs","authors":"Jordan Holmén, William Chaplin, Tamara Del Vecchio","doi":"10.1111/jnp.12363","DOIUrl":"10.1111/jnp.12363","url":null,"abstract":"<p>Executive function (EF) is represented by a multidimensional set of measures. The central EFs considered are inhibitory control, working memory and cognitive flexibility (task shifting). Unlike other ability constructs, it has proven difficult to identify latent factors that underlie EF. Research has often taken a factor analytic approach for grouping executive functioning tasks. However, this approach has often proven unsuccessful. We aimed to compare factor analysis to a network analytic approach, as network analysis can summarize the pattern of relationships among elements without creating latent constructs. One hundred and thirteen undergraduate students completed a series of nine executive functioning tasks. In comparing exploratory factor analysis to network analysis, we found neither approach provided a compelling higher order grouping of EF measures.</p>","PeriodicalId":197,"journal":{"name":"Journal of Neuropsychology","volume":"18 3","pages":"391-399"},"PeriodicalIF":1.8,"publicationDate":"2024-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139641325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tobias Bormann, Christoph P. Kaller, Caterina Kulyk, Nele Demeyere, Cornelius Weiller
{"title":"The German version of the Oxford Cognitive Screen (D-OCS): Normative data and validation in acute stroke and a mixed neurological sample","authors":"Tobias Bormann, Christoph P. Kaller, Caterina Kulyk, Nele Demeyere, Cornelius Weiller","doi":"10.1111/jnp.12359","DOIUrl":"10.1111/jnp.12359","url":null,"abstract":"<p>Given the frequency of stroke worldwide, tools for neuropsychological assessment of patients with acute stroke are needed to identify cognitive impairments, guide rehabilitation efforts and allow for a prognosis of outcome. However, requirements for assessment tools for acute cognitive deficits differ substantially from tests for chronic neuropsychological impairments and screening tools for suspected dementia. The Oxford Cognitive Screen (OCS) has been developed as a quick to administer neurocognitive screening for acute neurological patients providing information on various cognitive domains. It is available in different languages. The present study reports cut-off scores, parallel-test reliability and concurrent validity of the German version (D-OCS). Following standardized language adaptation and translation, the D-OCS was administered to 100 healthy individuals to generate cut-off scores (5th percentile). Subsequently, 88 neurological patients were assessed with both versions of the D-OCS as well as other tests to evaluate reliability and validity of the D-OCS subscales. In a further study, the D-OCS was compared to the MoCA test in 65 acute stroke patients revealing comparable sensitivity but also differences between both tools. The cut-off scores were comparable to other international versions of the OCS. Intraclass correlations were highly significant and document reliability of the D-OCS subtests. Scores on subtests correlated significantly with independent tests securing validity. Comparison with the MoCA revealed comparable sensitivity and specificity. The D-OCS is a reliable and valid assessment tool well suited for patients with acute stroke. Differences to the MoCA test are discussed.</p>","PeriodicalId":197,"journal":{"name":"Journal of Neuropsychology","volume":"18 3","pages":"377-390"},"PeriodicalIF":1.8,"publicationDate":"2024-01-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jnp.12359","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139490389","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Marine Thomasson, Daniel Perez-Marcos, Sonia Crottaz-Herbette, Fanny Brenet, Arnaud Saj, Thérèse Bernati, Andrea Serino, Tej Tadi, Olaf Blanke, Roberta Ronchi
{"title":"An immersive virtual reality tool for assessing left and right unilateral spatial neglect","authors":"Marine Thomasson, Daniel Perez-Marcos, Sonia Crottaz-Herbette, Fanny Brenet, Arnaud Saj, Thérèse Bernati, Andrea Serino, Tej Tadi, Olaf Blanke, Roberta Ronchi","doi":"10.1111/jnp.12361","DOIUrl":"10.1111/jnp.12361","url":null,"abstract":"<p>The reported rate of the occurrence of unilateral spatial neglect (USN) is highly variable likely due to the lack of validity and low sensitivity of classical tools used to assess it. Virtual reality (VR) assessments try to overcome these limitations by proposing immersive and complex environments. Nevertheless, existing VR-based tasks are mostly focused only on near space and lack analysis of psychometric properties and/or clinical validation. The present study evaluates the clinical validity and sensitivity of a new immersive VR-based task to assess USN in the extra-personal space and examines the neuronal correlates of deficits of far space exploration. The task was administrated to two groups of patients with right (<i>N</i> = 28) or left (<i>N</i> = 11) hemispheric brain lesions, also undergoing classical paper-and-pencil assessment, as well as a group of healthy participants. Our VR-based task detected 44% of neglect cases compared to 31% by paper-and-pencil tests in the total sample. Importantly, 30% of the patients (with right or left brain lesions) with no clear sign of USN on the paper-and-pencil tests performed outside the normal range in the VR-based task. Voxel lesion-symptom mapping revealed that deficits detected in VR were associated with lesions in insular and temporal cortex, part of the neural network involved in spatial processing. These results show that our immersive VR-based task is efficient and sensitive in detecting mild to strong manifestations of USN affecting the extra-personal space, which may be undetected using standard tools.</p>","PeriodicalId":197,"journal":{"name":"Journal of Neuropsychology","volume":"18 3","pages":"349-376"},"PeriodicalIF":1.8,"publicationDate":"2024-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139471750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ryan C. Thompson, Meredith R. D. Melinder, Heather A. Daly, Stacie L. Warren
{"title":"Disentangling effects of remote mild traumatic brain injury characteristics and posttraumatic stress on processing speed and executive function in veterans","authors":"Ryan C. Thompson, Meredith R. D. Melinder, Heather A. Daly, Stacie L. Warren","doi":"10.1111/jnp.12360","DOIUrl":"10.1111/jnp.12360","url":null,"abstract":"<p>Mild traumatic brain injury (mTBI) and posttraumatic stress are prevalent in military service members and share objective and subjective cognitive symptoms, complicating recovery. We investigated the effects of remote mTBI characteristics and current posttraumatic stress symptoms on neuropsychological performance in 152 veterans with a history of remote mTBI and current cognitive concerns. Participants completed clinical neuropsychological evaluations within a Veterans Affairs Level-II TBI/Polytrauma outpatient clinic (<i>i.e.</i> tertiary trauma care center for US military veterans outside of a research or teaching hospital setting). Archival data analysis of mTBI injury characteristics, clinical diagnoses, scores on the Posttraumatic Stress Disorder Checklist–Military Version (PCL-M) and performance on tests of processing speed, attention and executive function was conducted. Hierarchical linear regression demonstrated that elevated PCL-M scores were associated with slower performance on trail making test (TMT) Parts A and B (<i>p</i> < .016). PCL-M symptoms moderated the effect of alteration of consciousness (AOC) on TMT performance, with endorsement of AOC associated with better performance, but only when PCL-M scores were high (<i>p</i> < .005). Follow-up mediation analyses demonstrated that PCL-M score fully mediated the relationship between AOC and TMT-A performance and partially mediated the relationship between AOC and TMT-B performance. Post-hoc analyses meant to separate the impact of processing speed on TMT-B were all non-significant. Remote mTBI characteristics, specifically AOC, were not associated with decrements in cognitive performance. Posttraumatic symptoms were associated with worse processing speed, suggesting that psychological distress and psychopathology are contributing factors in understanding and treating persistent cognitive distress following remote mTBI.</p>","PeriodicalId":197,"journal":{"name":"Journal of Neuropsychology","volume":"18 3","pages":"333-348"},"PeriodicalIF":1.8,"publicationDate":"2024-01-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139424162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Claire Boutoleau-Bretonnière, Dimitrios Kapogiannis, Mohamad El Haj
{"title":"The guaranteed euros: Probabilistic discounting in behavioural-variant frontotemporal dementia","authors":"Claire Boutoleau-Bretonnière, Dimitrios Kapogiannis, Mohamad El Haj","doi":"10.1111/jnp.12357","DOIUrl":"10.1111/jnp.12357","url":null,"abstract":"<p>Financial decision-making requires trading off between guaranteed and probabilistic outcomes and between immediate and delayed ones. While research has demonstrated that patients with behavioural-variant frontotemporal dementia (bvFTD) prefer immediate rewards at the expense of future ones (i.e. temporal discounting), little is known about how patients choose between smaller, guaranteed and larger, but probabilistic, outcomes (i.e. probabilistic discounting). We thus investigated probabilistic discounting by inviting 18 patients with bvFTD and 20 control participants to choose between fixed smaller monetary amounts and a fixed larger monetary amount with a variated probability of occurrence (e.g. ‘Would you rather have 40€ for sure or a 20% chance of winning 100€?’). Results demonstrated lower scores, indicating higher risk tolerance, on the probabilistic discounting task in patients with bvFTD (while impulsively choosing more immediate rewards on the temporal discounting task) compared to control participants. Probabilistic discounting was significantly correlated with a decline in general cognitive performance in patients with bvFTD. When dealing between smaller, guaranteed, and larger, but probabilistic, rewards, patients with bvFTD tend to prefer guaranteed rewards and discount the uncertain ones.</p>","PeriodicalId":197,"journal":{"name":"Journal of Neuropsychology","volume":"18 2","pages":"239-250"},"PeriodicalIF":1.8,"publicationDate":"2023-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138883755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ellen Collée, Esther van den Berg, Evy Visch-Brink, Arnaud Vincent, Clemens Dirven, Djaina Satoer
{"title":"Differential contribution of language and executive functioning to verbal fluency performance in glioma patients","authors":"Ellen Collée, Esther van den Berg, Evy Visch-Brink, Arnaud Vincent, Clemens Dirven, Djaina Satoer","doi":"10.1111/jnp.12356","DOIUrl":"10.1111/jnp.12356","url":null,"abstract":"<p>Glioma patients often suffer from deficits in language and executive functioning. Performance in verbal fluency (generating words within one minute according to a semantic category–category fluency, or given letter–letter fluency) is typically impaired in this patient group. While both language and executive functioning play a role in verbal fluency, the relative contribution of both domains remains unclear. We aim to retrospectively investigate glioma patients' performance on verbal and nonverbal fluency and to explore the influence of language and executive functioning on verbal fluency. Sixty-nine adults with gliomas in eloquent areas underwent a neuropsychological test battery (verbal fluency, nonverbal fluency, language, and executive functioning tests) before surgery (T1) and a subgroup of 31 patients also at three (T2) and twelve months (T3) after surgery. Preoperatively, patients were impaired in all verbal fluency tasks and dissociations were found based on tumour location. In contrast, nonverbal fluency was intact. Different language and executive functioning tests predicted performance on category fluency animals and letter fluency, while no significant predictors for category fluency professions were found. The longitudinal results indicated that category fluency professions deteriorated after surgery (T1–T2, T1–T3) and that nonverbal fluency improved after surgery (T1–T3, T2–T3). Verbal fluency performance can provide information on different possible underlying deficits in language and executive functioning in glioma patients, depending on verbal fluency task selection. Efficient task (order) selection can be based on complexity. Category fluency professions can be selected to detect more permanent long-term deficits.</p>","PeriodicalId":197,"journal":{"name":"Journal of Neuropsychology","volume":"18 S1","pages":"19-40"},"PeriodicalIF":1.8,"publicationDate":"2023-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jnp.12356","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138794320","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Elena Salillas, Concetta Luisi, Giorgio Arcara, Elif Nur Varlı, Domenico d'Avella, Carlo Semenza
{"title":"Verb generation for presurgical mapping: Gaining specificity","authors":"Elena Salillas, Concetta Luisi, Giorgio Arcara, Elif Nur Varlı, Domenico d'Avella, Carlo Semenza","doi":"10.1111/jnp.12355","DOIUrl":"10.1111/jnp.12355","url":null,"abstract":"<p>Verb generation is among the most frequently used tasks in presurgical mapping. Because this task involves many processes, the overall brain effects are not specific. While it is necessary to identify the whole network involving noun comprehension or semantic retrieval and lexical selection to produce the verb, isolation of those components is also crucial. Here, we present data from four patients undergoing presurgical brain mapping. The study implied a reanalysis of magnetoencephalography data with a recategorization of the used items. It aimed to extract the task component that relies on the inferior frontal gyrus (IFG). The task could be applied with higher specificity when targeting frontal areas. For that, we based item classification on the selection demands imposed by the noun. It is a robust finding that the IFG carries out this selection and that a quantitative index can be calculated for each noun, which depends on the selection effort (<i>Proceedings of the National Academy of Sciences of the United States of America</i>, 1997; <b>94</b>(26):14792–14797, <i>Proceedings of the National Academy of Sciences of the United States of America</i>, 1998; <b>95</b>(26):15855–15860). Data showed focality and specificity, with a correlation between this derived index and source activations in the inferior frontal gyrus for all patients. Strikingly, we detected when the right-hemisphere homologue area was involved in the selection process in two patients showing reorganization or language right lateralization. The present data are a step towards a dissection of broad specific tasks frequently used in presurgical protocols.</p>","PeriodicalId":197,"journal":{"name":"Journal of Neuropsychology","volume":"18 S1","pages":"183-204"},"PeriodicalIF":1.8,"publicationDate":"2023-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jnp.12355","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138561898","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Megan S. Barker, Amelia Ceslis, Rosemary Argall, Pamela McCombe, Robert D. Henderson, Gail A. Robinson
{"title":"Verbal and nonverbal fluency in amyotrophic lateral sclerosis","authors":"Megan S. Barker, Amelia Ceslis, Rosemary Argall, Pamela McCombe, Robert D. Henderson, Gail A. Robinson","doi":"10.1111/jnp.12354","DOIUrl":"10.1111/jnp.12354","url":null,"abstract":"<p>Amyotrophic lateral sclerosis (ALS) is a multi-system disorder that commonly affects cognition and behaviour. Verbal fluency impairments are consistently reported in ALS patients, and we aimed to investigate whether this deficit extends beyond the verbal domain. We further aimed to determine whether deficits are underpinned by a primary intrinsic response generation impairment (<i>i.e</i>., a global reduction across tasks), potentially related to apathy, or an inability to maintain responding over time (<i>i.e</i>., a ‘drop off’ pattern). Twenty-two ALS patients and 21 demographically-matched controls completed verbal and nonverbal fluency tasks (phonemic/semantic word fluency, design fluency, gesture fluency and ideational fluency), requiring the generation of responses over a specified time period. Fluency performance was analysed in terms of the overall number of novel items produced, as well as the number of items produced in the first ‘initiation’ and the remaining ‘maintenance’ time periods. ALS patients' overall performance was not globally reduced across tasks. Patients were impaired only on meaningful gesture fluency, which requires the generation of gestures that communicate meaning (<i>e.g</i>., waving). On phonemic fluency, ALS patients showed a ‘drop off’ pattern of performance, where they had difficulty maintaining responding over time, but this pattern was not evident on the other fluency tasks. Apathy did not appear to be related to fluency performance. The selective meaningful gesture fluency deficit, in the context of preserved meaningless gesture fluency, highlights that the retrieval of action knowledge may be weakened in early ALS.</p>","PeriodicalId":197,"journal":{"name":"Journal of Neuropsychology","volume":"18 2","pages":"265-285"},"PeriodicalIF":1.8,"publicationDate":"2023-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jnp.12354","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138297895","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Guilbert, T.-G. Bara, T. Bouchara, M. Gaffard, C. Bourlon
{"title":"Feasibility and relevance of an immersive virtual reality cancellation task assessing far space in unilateral spatial neglect","authors":"A. Guilbert, T.-G. Bara, T. Bouchara, M. Gaffard, C. Bourlon","doi":"10.1111/jnp.12353","DOIUrl":"10.1111/jnp.12353","url":null,"abstract":"<p>Unilateral spatial neglect (USN) is a highly prevalent neuropsychological syndrome. However, its assessment in clinical practice, mainly based on paper-and-pencil tests, encounters limits as only near space, called peripersonal, is assessed. However, USN is a multicomponent syndrome that can also affect far space, called extrapersonal. This space is not assessed in current clinical assessment although it can be more impacted than peripersonal space. Immersive virtual reality (VR) allows developing tasks in far space to assess this heterogeneity. This study aimed to test the feasibility and the relevance of an immersive VR task to assess far space. A cancellation task, the Bells test, was used in its original paper-and-pencil version and was also adapted into a far immersive VR version. Ten patients with left USN and sixteen age-matched healthy participants were included. A single-case method was performed to investigate the performance of each patient. Although five patients showed very similar results between both versions, the five others exhibited a dissociation with a more severe impairment in the VR version. Three of these five patients significantly differed from the healthy participants only on the VR version. As USN in far space is not brought to light by paper-and-pencil tests, immersive VR appears as a promising tool to detect USN affecting this space.</p>","PeriodicalId":197,"journal":{"name":"Journal of Neuropsychology","volume":"18 2","pages":"300-311"},"PeriodicalIF":1.8,"publicationDate":"2023-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jnp.12353","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71519839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}