Journal of Neuropsychology最新文献

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The influence of motor and non-motor characteristics of Parkinson's disease on motor imagery vividness 帕金森病运动与非运动特征对运动意象生动性的影响。
IF 1.8 4区 心理学
Journal of Neuropsychology Pub Date : 2026-06-09 Epub Date: 2026-03-26 DOI: 10.1111/jnp.70040
Camilla Woodrow-Hill, Judith Bek, Megan Readman, Emma Gowen, Stefan Vogt, Ellen Poliakoff
{"title":"The influence of motor and non-motor characteristics of Parkinson's disease on motor imagery vividness","authors":"Camilla Woodrow-Hill,&nbsp;Judith Bek,&nbsp;Megan Readman,&nbsp;Emma Gowen,&nbsp;Stefan Vogt,&nbsp;Ellen Poliakoff","doi":"10.1111/jnp.70040","DOIUrl":"10.1111/jnp.70040","url":null,"abstract":"<p>Motor imagery (MI) can facilitate movement in healthy individuals and patient populations. People with Parkinson's (PwP) experience debilitating motor symptoms, yet appear to have relatively intact MI capabilities, which may position MI as an effective therapeutic adjunct to existing interventions for PwP. However, individual differences in healthy individuals, such as cognitive factors and depression, as well as symptom severity in PwP, have been shown to influence MI, which may moderate its therapeutic impact. In the present study, data from 56 PwP were analysed using linear mixed-effect modelling to explore whether motor symptoms, cognitive function and depression were associated with MI vividness. Overall motor symptom severity was not associated with MI vividness, and specific symptoms (bradykinesia and tremor) did not show consistent relationships. This suggests that individual differences in symptom expression may make it difficult to identify a clear relationship between MI and motor symptoms. Action fluency (verb generation) was positively associated with right-lateralised MI vividness. However, working memory, general language fluency and depression were not associated with MI vividness. The relationship between generating verbs and MI vividness is consistent with theories of grounded and embodied cognition. Action fluency could thus potentially be used to predict the effectiveness of MI-based interventions in PwP.</p>","PeriodicalId":197,"journal":{"name":"Journal of Neuropsychology","volume":"20 2","pages":"410-425"},"PeriodicalIF":1.8,"publicationDate":"2026-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jnp.70040","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147508202","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Educational attainment mitigates hippocampal-related episodic memory decline in individuals at risk of Alzheimer's disease 受教育程度减轻了阿尔茨海默病风险个体海马相关情景记忆衰退。
IF 1.8 4区 心理学
Journal of Neuropsychology Pub Date : 2026-06-09 Epub Date: 2026-03-24 DOI: 10.1111/jnp.70039
Annalise Aleta LaPlume, Samira Mellah, the Consortium for the early identification of Alzheimer's disease-Quebec (CIMA-Q), Maria Natasha Rajah, Sylvie Belleville
{"title":"Educational attainment mitigates hippocampal-related episodic memory decline in individuals at risk of Alzheimer's disease","authors":"Annalise Aleta LaPlume,&nbsp;Samira Mellah,&nbsp;the Consortium for the early identification of Alzheimer's disease-Quebec (CIMA-Q),&nbsp;Maria Natasha Rajah,&nbsp;Sylvie Belleville","doi":"10.1111/jnp.70039","DOIUrl":"10.1111/jnp.70039","url":null,"abstract":"<p>Ageing and Alzheimer's disease lead to declines in the brain region underlying memory for past events (hippocampus), and subsequently in memory for past events (episodic memory). However, some people show considerable adaptability in maintaining cognitive processes despite brain ageing or disease. The cognitive reserve model proposes that individual factors (e.g., higher education) may provide cognitive resilience. We measured whether the expected hippocampal-memory association differs according to educational attainment (a proxy of cognitive reserve). At baseline, 62 older adults (65–88 years old) at risk of Alzheimer's disease reported the amount of education completed and received anatomical 3D-T1-w structural MRIs to measure hippocampal volume. They completed a Face-Name Association episodic memory task at baseline, 2 years later, and 4 years later. Educational attainment significantly moderated the effect of hippocampal volume on episodic memory over time, <i>β</i> = −1.97 (<i>SE</i> = .93). Lower hippocampal volume caused greater memory decline at low (mean − 1 SD), but not at moderate (mean) or high (mean + 1 SD) education levels. A Johnson–Neyman analysis revealed that over 14 years of educational attainment is the threshold to eliminate a significant hippocampal-memory effect. The results did not differ by sex. Findings support the cognitive reserve model that individual factors, such as educational attainment, contribute to a cognitive reserve that enables better cognitive performance than would be expected given ageing or disease-related brain changes. Importantly, the findings specify the amount of educational attainment that is protective. Over 14 years of education mitigates hippocampal-related memory decline in people at the risk of Alzheimer's disease.</p>","PeriodicalId":197,"journal":{"name":"Journal of Neuropsychology","volume":"20 2","pages":"394-409"},"PeriodicalIF":1.8,"publicationDate":"2026-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jnp.70039","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147502701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Psychometric properties of the Ekman 60-Faces Test in clinical populations: A systematic review and meta-analysis. Ekman 60-Faces测试在临床人群中的心理测量特性:系统回顾和荟萃分析。
IF 1.8 4区 心理学
Journal of Neuropsychology Pub Date : 2026-06-02 DOI: 10.1111/jnp.70052
Linde Assendelft, Jackie M Poos, Esther van den Berg
{"title":"Psychometric properties of the Ekman 60-Faces Test in clinical populations: A systematic review and meta-analysis.","authors":"Linde Assendelft, Jackie M Poos, Esther van den Berg","doi":"10.1111/jnp.70052","DOIUrl":"https://doi.org/10.1111/jnp.70052","url":null,"abstract":"<p><p>The Ekman 60-Faces Test is widely used to assess facial emotion recognition, but information on its validity and reliability is scarce. This systematic review evaluated the reporting of psychometric properties across clinical populations. A total of 159 studies (n = 5978) were included: case-control (n = 109), single cohort (n = 37) and review/norm studies (n = 13). Data were extracted on the reporting of structural validity, internal consistency, measurement invariance, test-retest reliability, criterion validity and construct validity. A meta-analysis was performed, assessing effect sizes (Hedges' d) to summarize differences in performance on the Ekman 60-Faces Test in different categories of clinical groups compared with control participants. Results showed that the majority of studies used the validated version by Young et al. (2002; 42%). Fewer than 10% of the studies addressed criterion validity, internal consistency, measurement invariance, structural validity or test-retest reliability. Associations with demographic variables were reported in 23% of studies. Meta-analysis revealed significantly larger effects in neurodegenerative populations (d = -1.09) than in psychiatric (d = -.70, Q<sub>m</sub> = 5.06, p < .05) and acquired brain injury (d = -.78, Q<sub>m</sub> = 5.45, p < .05) populations.</p>","PeriodicalId":197,"journal":{"name":"Journal of Neuropsychology","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2026-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148142172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Social information processing in autism: The role of cognitive empathy in moral responding. 孤独症患者的社会信息加工:认知共情在道德反应中的作用。
IF 1.8 4区 心理学
Journal of Neuropsychology Pub Date : 2026-05-25 DOI: 10.1111/jnp.70054
Mia Davies, Amy Brown, Stephen J C Hearps, Mahlee C Langdon, Ben Collins, Miriam H Beauchamp, Vicki A Anderson
{"title":"Social information processing in autism: The role of cognitive empathy in moral responding.","authors":"Mia Davies, Amy Brown, Stephen J C Hearps, Mahlee C Langdon, Ben Collins, Miriam H Beauchamp, Vicki A Anderson","doi":"10.1111/jnp.70054","DOIUrl":"https://doi.org/10.1111/jnp.70054","url":null,"abstract":"<p><p>Autistic individuals experience challenges in social functioning and have demonstrated atypical patterns of social cognition. However, limitations exist regarding the ecological validity of measures used to assess social cognition in autism, and the relationships between socio-cognitive processes are unclear. The current study aimed to investigate social cognition in autistic children using a novel assessment tool, comparing their social interpretation, perspective-taking abilities (i.e. cognitive empathy) and moral reasoning to that of neurotypical controls. The relationships between these socio-cognitive processes were explored in the context of socio-moral processing. Thirty-six participants were included in the autism group (86% male, aged 8-17 years-old) and 36 participants formed an age- and sex-matched neurotypical control group (86% male, aged 8-15 years-old). The autism group scored significantly lower than the neurotypical group in cognitive empathy only, t(69.37) = 5.95, p < .001. Higher levels of cognitive empathy, but not social interpretation, were significantly positively associated with moral responding, only in the autism group, R<sup>2</sup> = .11, F(1, 32) = 5.24, p = .029. Findings indicate the importance of perspective-taking abilities to social cognition difficulties in autism.</p>","PeriodicalId":197,"journal":{"name":"Journal of Neuropsychology","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2026-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148012688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Social cognition in children and adolescents with fragile X syndrome: A comparison with individuals with autism symptoms and typical development. 儿童和青少年脆性X综合征的社会认知:与自闭症症状和典型发展个体的比较
IF 1.8 4区 心理学
Journal of Neuropsychology Pub Date : 2026-04-09 DOI: 10.1111/jnp.70048
Kamil R Hiralal, Nienke Bouw, Britt R Kok, Kyra Lubbers, Bram Dierckx, Kirstin Greaves-Lord, Manon H J Hillegers, Gwendolyn C Dieleman, Sabine E Mous
{"title":"Social cognition in children and adolescents with fragile X syndrome: A comparison with individuals with autism symptoms and typical development.","authors":"Kamil R Hiralal, Nienke Bouw, Britt R Kok, Kyra Lubbers, Bram Dierckx, Kirstin Greaves-Lord, Manon H J Hillegers, Gwendolyn C Dieleman, Sabine E Mous","doi":"10.1111/jnp.70048","DOIUrl":"https://doi.org/10.1111/jnp.70048","url":null,"abstract":"<p><p>Most individuals with fragile X syndrome (FXS) exhibit symptoms of autism spectrum disorder (ASD), suggesting a substantial overlap in social cognitive profiles. This cross-sectional study aimed to explore social cognitive abilities in children and adolescents with FXS in comparison with an age-matched heterogeneous ASD group and typically developing (TD) peers. Key domains assessed included basic visual social attention towards faces, autonomic arousal in reaction to conflicting emotional information and Theory of Mind (ToM). Participants comprised 14 children with FXS, 24 with ASD and 19 TD controls, aged 6-18 years. Visual attention and implicit emotion recognition were measured using an emotional oddball paradigm using gaze behaviour and pupillometric analysis, and ToM was assessed with the NEPSY-II neuropsychological test battery ToM subtest. Results indicated that children and adolescents with FXS directed their gaze less towards relevant social-emotional information (i.e., faces and especially eyes), compared with both the ASD and TD groups. Regarding implicit emotion recognition, the attentional disparity between the FXS group and the TD group was reduced when conflicting multisensory emotional information was presented, rather than congruent cues. Next, a diminished pupillary response to conflicting emotional information was found in the FXS group, as compared with the ASD group. Additionally, the FXS group showed difficulties with ToM, compared with the ASD and TD groups. These findings suggest that both deviations in basic and higher-order social cognitive abilities may contribute to the social difficulties experienced by individuals with FXS and may partly account for the high incidence of ASD diagnoses in this population.</p>","PeriodicalId":197,"journal":{"name":"Journal of Neuropsychology","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2026-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147637435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Differential cued recall memory impairment in mild cognitive impairment due to Alzheimer's disease versus Parkinson's disease 阿尔茨海默病与帕金森病引起的轻度认知障碍的差异提示回忆记忆障碍。
IF 1.8 4区 心理学
Journal of Neuropsychology Pub Date : 2026-03-11 Epub Date: 2025-08-28 DOI: 10.1111/jnp.70010
Ondrej Bezdicek, Jiří Motýl, Tomáš Nikolai, Adéla Fendrych Mazancová, Jakub Hort, Robert Jech, Martin Vyhnálek, Hana Horáková
{"title":"Differential cued recall memory impairment in mild cognitive impairment due to Alzheimer's disease versus Parkinson's disease","authors":"Ondrej Bezdicek,&nbsp;Jiří Motýl,&nbsp;Tomáš Nikolai,&nbsp;Adéla Fendrych Mazancová,&nbsp;Jakub Hort,&nbsp;Robert Jech,&nbsp;Martin Vyhnálek,&nbsp;Hana Horáková","doi":"10.1111/jnp.70010","DOIUrl":"10.1111/jnp.70010","url":null,"abstract":"<p>Both Alzheimer's (AD) and Parkinson's disease (PD) are often associated with memory dysfunction, but their pathophysiological underpinnings differ. The current research aimed to differentiate specific profiles of memory impairment due to AD versus PD. We used controlled learning and cued recall paradigm based on the Memory Binding Test (MBT) in ‘clinically cognitively normal’ controls (CN; <i>n</i> = 161), in patients with amnestic mild cognitive impairment due to AD (AD-aMCI; <i>n</i> = 50) and due to PD (PD-MCI; <i>n</i> = 22), and in PD with normal cognition (<i>n</i> = 18) as based on performance in the neuropsychological battery to prevent circularity in diagnostic decision-making. We applied analysis of covariance (ANCOVA) and Receiver Operating Characteristic (ROC) analysis to determine between-group differences and detection potential of the MBT. We found statistically large between-group differences with worse memory performance in paired cued recall conditions in AD-aMCI&lt;PD-MCI; AD-aMCI&lt;PD-NC; AD-aMCI&lt;CN (<i>p</i> &lt; .001 after Bonferroni correction), and to a lesser extent in PD-MCI&lt;CN (<i>p</i> = .039). However, PD-NC did not differ from PD-MCI, and PD-NC did not differ from CN (<i>p</i> &gt; .050). The detection potential of MBT paired cued recall for differentiating memory impairment in AD-aMCI from CN yielded an AUC of 90% (95% CI, 85–96) and an AUC of 91% (95% CI, 81–&gt;99) between AD-aMCI and PD-MCI. Associative memory and binding impairment are most pronounced in AD-aMCI in comparison to PD-MCI and controls. Overall, the MBT is an efficient tool for the differential diagnosis of memory impairment due to the two most common neurodegenerative diseases.</p>","PeriodicalId":197,"journal":{"name":"Journal of Neuropsychology","volume":"20 1","pages":"68-87"},"PeriodicalIF":1.8,"publicationDate":"2026-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12976840/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144937343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Understanding memory dynamics in stroke patients: Learning and forgetting patterns based on verbal recall 了解中风患者的记忆动态:基于言语回忆的学习和遗忘模式。
IF 1.8 4区 心理学
Journal of Neuropsychology Pub Date : 2026-03-11 Epub Date: 2025-07-15 DOI: 10.1111/jnp.70004
Selma Lugtmeijer, Edward H. F. de Haan, Roy P. C. Kessels
{"title":"Understanding memory dynamics in stroke patients: Learning and forgetting patterns based on verbal recall","authors":"Selma Lugtmeijer,&nbsp;Edward H. F. de Haan,&nbsp;Roy P. C. Kessels","doi":"10.1111/jnp.70004","DOIUrl":"10.1111/jnp.70004","url":null,"abstract":"<p>Memory deficits are common post stroke. Most episodic memory tests consist of a learning phase, immediate recall and a 30-min delayed recall test. Recent research suggests a proportion of stroke patients exhibit accelerated long-term forgetting after a longer delay. Based on a word-list learning test in stroke patients and controls, we demonstrate that stroke patients recalled fewer words after five learning trials, and on 30-min and 1-week delayed recall tests, caused by shallower learning curves and higher percentages of forgetting.</p>","PeriodicalId":197,"journal":{"name":"Journal of Neuropsychology","volume":"20 1","pages":"276-283"},"PeriodicalIF":1.8,"publicationDate":"2026-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12976844/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147429488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Differences in response inhibition between medication-free patients with obsessive-compulsive disorder with and without sensory phenomena 有无感觉现象的无药强迫症患者反应抑制的差异。
IF 1.8 4区 心理学
Journal of Neuropsychology Pub Date : 2026-03-11 Epub Date: 2025-10-11 DOI: 10.1111/jnp.70016
Keitaro Murayama, Hirofumi Tomiyama, Kenta Sashikata, Mingi Kang, Aikana Ohno, Kenta Kato, Akira Matsuo, Tomohiro Nakao
{"title":"Differences in response inhibition between medication-free patients with obsessive-compulsive disorder with and without sensory phenomena","authors":"Keitaro Murayama,&nbsp;Hirofumi Tomiyama,&nbsp;Kenta Sashikata,&nbsp;Mingi Kang,&nbsp;Aikana Ohno,&nbsp;Kenta Kato,&nbsp;Akira Matsuo,&nbsp;Tomohiro Nakao","doi":"10.1111/jnp.70016","DOIUrl":"10.1111/jnp.70016","url":null,"abstract":"<p>Obsessive-compulsive disorder (OCD) is a heterogeneous disorder, and approximately 70% of patients with OCD experience sensory phenomena (SP). Previous studies have revealed that patients with OCD exhibit a deficit in response inhibition (RI). However, few studies have investigated the relationship between SP and RI in patients with OCD. This study aimed to investigate differences in RI between non-comorbid, medication-free patients with OCD with and without SP. Thirty-seven patients with OCD with SP (OCD + SP), 27 without SP (OCD-noSP), and 50 controls (HCs) were compared in terms of RI using the stop-signal task. Both OCD groups had a deficit in RI compared with HCs, and no difference in RI was found between the OCD + SP and OCD-noSP groups. No correlation was observed between SP and stop-signal reaction time in the OCD + SP group. Our findings suggest that a deficit in RI is not related to SP in OCD.</p>","PeriodicalId":197,"journal":{"name":"Journal of Neuropsychology","volume":"20 1","pages":"132-143"},"PeriodicalIF":1.8,"publicationDate":"2026-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12976831/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145273246","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Frontal Assessment Battery: Reliability, validity and discriminative ability in a Spanish sample of amnestic mild cognitive impairment and Alzheimer's disease 正面评估组:西班牙健忘轻度认知障碍和阿尔茨海默病样本的信度、效度和判别能力。
IF 1.8 4区 心理学
Journal of Neuropsychology Pub Date : 2026-03-11 Epub Date: 2025-09-18 DOI: 10.1111/jnp.70011
Luis Heredia, María Marco, Nerea Carrión, Margarita Torrente
{"title":"Frontal Assessment Battery: Reliability, validity and discriminative ability in a Spanish sample of amnestic mild cognitive impairment and Alzheimer's disease","authors":"Luis Heredia,&nbsp;María Marco,&nbsp;Nerea Carrión,&nbsp;Margarita Torrente","doi":"10.1111/jnp.70011","DOIUrl":"10.1111/jnp.70011","url":null,"abstract":"<p>Dementia constitutes one of the most widespread neurological disorders, representing an important health concern due to its increasing prevalence. Among the various types of dementia, Alzheimer's disease (AD) is the most common in the elderly, characterized by episodic memory impairment and also a decline in executive functions. Mild cognitive impairment (MCI) is considered a transitional stage between normal ageing and dementia, often described as a pre-dementia state. Distinguishing between these states is of paramount importance for the detection and appropriate care of patients. Functional Assessment Battery (FAB) is a screening tool for assessing executive function. In this study, 36 healthy individuals (HC), 31 single-domain amnestic mild cognitive impairment (aMCI) patients, and 29 Alzheimer's disease (AD) patients were assessed using FAB to determine its reliability, validity, and discriminative validity in a Spanish sample. Results indicated a good internal consistency of FAB in the AD sample (α = .71), but not in the aMCI group (α = .49). Significant differences between HC and both aMCI and AD groups were observed in the total scores of FAB. The FAB also showed good accuracy in distinguishing between HC and patients (AUC = 0.85), with an estimated optimal cut-off point of 16.5. However, its ability to distinguish between aMCI and AD individuals was lower (AUC = 0.68). More studies are necessary to corroborate our results using larger samples.</p>","PeriodicalId":197,"journal":{"name":"Journal of Neuropsychology","volume":"20 1","pages":"88-100"},"PeriodicalIF":1.8,"publicationDate":"2026-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12976837/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145079153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Delayed recall from the primacy portion of a story predicts conversion of patients with mild cognitive impairment to Alzheimer's disease 从故事的首要部分延迟回忆预示着轻度认知障碍患者向阿尔茨海默病的转变。
IF 1.8 4区 心理学
Journal of Neuropsychology Pub Date : 2026-03-11 Epub Date: 2025-10-21 DOI: 10.1111/jnp.70017
Veronica Di Palma, Lucia Fadda, Valentina Massimi, Carla Leonardi, Maria Stefania De Simone, Carlo Caltagirone, Giovanni Augusto Carlesimo
{"title":"Delayed recall from the primacy portion of a story predicts conversion of patients with mild cognitive impairment to Alzheimer's disease","authors":"Veronica Di Palma,&nbsp;Lucia Fadda,&nbsp;Valentina Massimi,&nbsp;Carla Leonardi,&nbsp;Maria Stefania De Simone,&nbsp;Carlo Caltagirone,&nbsp;Giovanni Augusto Carlesimo","doi":"10.1111/jnp.70017","DOIUrl":"10.1111/jnp.70017","url":null,"abstract":"<p>The serial position effect is a well-established phenomenon characterised by better recall of items at the beginning and end of a list compared to those in the middle. A reduced primacy effect—reflected by diminished recall of items from the initial positions—has frequently been reported in individuals with Alzheimer's disease (AD) and Mild Cognitive Impairment (MCI). This study aimed to examine the serial position curve in the Prose Memory test and to assess whether recall accuracy from the primacy portion of the story can predict progression from MCI to AD. Sixty-two patients diagnosed with MCI were included. After 3 years, 30 patients progressed to AD (cMCI), while 32 remained stable (sMCI). Immediate and delayed recall performance for the three segments of the story (Primacy, Middle and Recency) was analysed. In the immediate recall trial, both MCI groups and healthy controls showed enhanced recall accuracy only for the Primacy portion of the story. In the delayed trial, a reduced primacy effect significantly distinguished cMCI from sMCI patients. Receiver Operating Characteristic (ROC) analysis indicated acceptable diagnostic accuracy of delayed Primacy recall in differentiating converters from stable MCI patients. Delayed Primacy recall in the Prose Memory test predicted conversion from MCI to AD. These results suggest that delayed Primacy recall in prose memory may serve as a non-invasive marker for identifying individuals at risk for AD progression.</p>","PeriodicalId":197,"journal":{"name":"Journal of Neuropsychology","volume":"20 1","pages":"144-153"},"PeriodicalIF":1.8,"publicationDate":"2026-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145335961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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