Pain Research and Treatment最新文献_第3页

Fear Avoidance Beliefs and Risk of Long-Term Sickness Absence: Prospective Cohort Study among Workers with Musculoskeletal Pain. 恐惧回避信念和长期缺勤的风险:肌肉骨骼疼痛工人的前瞻性队列研究。

Pain Research and Treatment Pub Date : 2018-09-02 eCollection Date: 2018-01-01 DOI: 10.1155/2018/8347120

Kenneth Jay, Sannie Vester Thorsen, Emil Sundstrup, Ramon Aiguadé, Jose Casaña, Joaquin Calatayud, Lars Louis Andersen

{"title":"Fear Avoidance Beliefs and Risk of Long-Term Sickness Absence: Prospective Cohort Study among Workers with Musculoskeletal Pain.","authors":"Kenneth Jay, Sannie Vester Thorsen, Emil Sundstrup, Ramon Aiguadé, Jose Casaña, Joaquin Calatayud, Lars Louis Andersen","doi":"10.1155/2018/8347120","DOIUrl":"https://doi.org/10.1155/2018/8347120","url":null,"abstract":"Background and objective: Musculoskeletal pain is common in the population. Negative beliefs about musculoskeletal pain and physical activity may lead to avoidance behavior resulting in absence from work. The present study investigates the influence of fear avoidance beliefs on long-term sickness absence.Methods: Workers of the general working population with musculoskeletal pain (low back, neck/shoulder, and/or arm/hand pain; n = 8319) from the Danish Work Environment Cohort Study were included. Long-term sickness absence data were obtained from the Danish Register for Evaluation and Marginalization (DREAM). Time-to-event analyses (cox regression) controlled for various confounders estimated the association between fear avoidance beliefs (very low, low, moderate [reference category], high, and very high) at baseline and long-term sickness absence (LTSA; ≥6 consecutive weeks) during a 2-year follow-up.Results: During the 2-year follow-up, 10.2% of the workers experienced long-term sickness absence. In the fully adjusted model, very high-level fear avoidance increased the risk of LTSA with hazard ratio (HR) of 1.48 (95% CI 1.15-1.90). Similar results were seen analyses stratified for occupational physical activity, i.e., sedentary workers (HR 1.72 (95% CI 1.04-2.83)) and physically active workers (HR 1.48 (95% CI 1.10-2.01)).Conclusion: A very high level of fear avoidance is a risk factor for long-term sickness absence among workers with musculoskeletal pain regardless of the level of occupational physical activity. Future interventions should target fear avoidance beliefs through information and campaigns about the benefits of staying active when having musculoskeletal pain.","PeriodicalId":19786,"journal":{"name":"Pain Research and Treatment","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2018/8347120","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36515472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 12

Preemptive Analgesia in Total Knee Arthroplasty: Comparing the Effects of Single Dose Combining Celecoxib with Pregabalin and Repetition Dose Combining Celecoxib with Pregabalin: Double-Blind Controlled Clinical Trial. 全膝关节置换术中的先期镇痛：比较单剂量联合塞来昔布和普瑞巴林以及重复剂量联合塞来昔布和普瑞巴林的效果：双盲对照临床试验。

Pain Research and Treatment Pub Date : 2018-08-07 eCollection Date: 2018-01-01 DOI: 10.1155/2018/3807217

Andri M T Lubis, Rangga B V Rawung, Aida R Tantri

{"title":"Preemptive Analgesia in Total Knee Arthroplasty: Comparing the Effects of Single Dose Combining Celecoxib with Pregabalin and Repetition Dose Combining Celecoxib with Pregabalin: Double-Blind Controlled Clinical Trial.","authors":"Andri M T Lubis, Rangga B V Rawung, Aida R Tantri","doi":"10.1155/2018/3807217","DOIUrl":"10.1155/2018/3807217","url":null,"abstract":"Acute pain is the most common early complication after total knee arthroplasty causing delayed mobilization and increased demands of morphine, leading to higher operative cost. Several studies have assessed the effectiveness, side-effects, and ease of use of various analgesics. Preemptive analgesia with combined celecoxib and pregabalin has been reported to yield positive outcomes. In this randomized, double-blind controlled clinical trial, 30 subjects underwent surgery for total knee arthroplasty using 15-20mg bupivacaine 5% epidural anesthesia. All subjects were divided into three groups. Group 1 was given celecoxib 400mg and pregabalin 150mg 1 hour before the operation, Group 2 was given celecoxib 200mg and pregabalin 75mg twice daily starting from 3 days before the operation, and Group 3 was given a placebo. The outcome was measured with Visual Analog Scale, knee range of motion, and postoperative mobilization. There was a significant difference in postoperative morphine usage between the groups that were administered with preemptive analgesia and the placebo group, but no significant difference was found between Group 1 and Group 2 that were given preemptive analgesia at different doses. ROM and postoperative mobilization were not significantly different among the three groups. Two patients in the first group, one patient in the second group, and one patient in the third group developed nausea. Preemptive analgesia is proven to reduce postoperative usage of morphine independent of the dosage. We recommend the use of combined celecoxib and pregabalin as preemptive analgesia after the total knee arthroplasty procedure. This trial is registered with NCT03523832 (ClinicalTrials.gov).","PeriodicalId":19786,"journal":{"name":"Pain Research and Treatment","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6106806/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36453967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Role of Nurses' Uncertainty in Decision-Making Process of Pain Management in People with Dementia. 护士不确定性在痴呆患者疼痛管理决策过程中的作用。

Pain Research and Treatment Pub Date : 2018-08-01 eCollection Date: 2018-01-01 DOI: 10.1155/2018/7281657

Mohammad Rababa

引用次数: 14

The Consumption of Cannabis by Fibromyalgia Patients in Israel. 以色列纤维肌痛患者的大麻消费量。

Pain Research and Treatment Pub Date : 2018-07-22 eCollection Date: 2018-01-01 DOI: 10.1155/2018/7829427

George Habib, Irit Avisar

{"title":"The Consumption of Cannabis by Fibromyalgia Patients in Israel.","authors":"George Habib, Irit Avisar","doi":"10.1155/2018/7829427","DOIUrl":"https://doi.org/10.1155/2018/7829427","url":null,"abstract":"Objective: To report on the habits of cannabis consumption among fibromyalgia patients in Israel.Patients and methods: An Internet-based questionnaire was posted to three large fibromyalgia Facebook groups in our country. The questionnaire was anonymous and included demographic, clinical, and cannabis-related questions, including acquisition of a license for medical cannabis (MC) method and amount of cannabis consumption; need to buy cannabis beyond the medical allowance; effect of cannabis on pain, sleep, depression, and anxiety; adverse effects of cannabis; feelings of dependence on cannabis or other meds; the involvement of family members; tendency to drive after using cannabis; and employment and social disability status.Results: Of 2,705 people, 383 (14%) responded to the questionnaire, with a mean age of 42.2±14.2 years. Of the responders, 84% reported consuming cannabis, and 44% were licensed for MC. The mean amount per month of cannabis consumed was 31.4±16.3g, and 80% of cannabis consumers (CC) smoked pure cannabis or cannabis mixed with tobacco. Pain relief was reported by 94% of CC, while 93% reported improved sleep quality, 87% reported improvement in depression, and 62% reported improvement in anxiety. Of MC-licensed CC, 55% bought cannabis beyond the medical allowance on the black market. Adverse effects were reported by 12% of CC. Only 8% reported dependence on cannabis. Most CC (64%) worked either full- or part-time jobs, and 74% reported driving \"as usual\" under cannabis use.Conclusions: Cannabis consumption among fibromyalgia patients in our country is very common and is mostly not licensed. Nearly all CC reported favorable effects on pain and sleep, and few reported adverse effects or feeling of dependence on cannabis.","PeriodicalId":19786,"journal":{"name":"Pain Research and Treatment","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2018/7829427","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36421251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 21

The Effectiveness of Orofacial Pain Therapy in Indonesia: A Cross-Sectional Study. 印度尼西亚口腔面部疼痛治疗的有效性：一项横断面研究。

Pain Research and Treatment Pub Date : 2018-07-18 DOI: 10.1155/2018/6078457

T Maulina, G Yubiliana, R Rikmasari

{"title":"The Effectiveness of Orofacial Pain Therapy in Indonesia: A Cross-Sectional Study.","authors":"T Maulina, G Yubiliana, R Rikmasari","doi":"10.1155/2018/6078457","DOIUrl":"10.1155/2018/6078457","url":null,"abstract":"Objectives: As the most complained oral problems in Indonesia, the therapy of orofacial pain has to be constantly evaluated. The objective of the current study was to evaluate the effectiveness of orofacial pain therapy in Indonesia.Methods: This study recruited 5412 (3816 female; 1596 male) participants from 27 districts in West Java province. Half of the participants (2714) were recruited from those who were treated at community health centers whilst the rest were those who were treated at private dental clinics. A Likert-scale questionnaire that consists of nine questions that were divided to three subsections was used. The first subsection of the questionnaire evaluated the participants' post-therapy basic oral functions (three questions), and the second part evaluated the participants' post-therapy pain intensity and frequency (three questions), whilst the last part evaluated the participants' post-therapy activities (three questions). All data were then cross-tabulated and correlated by using Spearman correlation.Result: The current study revealed that out of 5412 participants, 4023 (74.33%) participants claimed that the therapy has enabled them to perform their work activity as usual, whilst 2576 (59.2%) claimed that the therapy has decreased the intensity of the pain moderately. A significant (p < 0.01) correlation (r = 0.1) between the type of dental facility visited and the total score of the therapy effectiveness was revealed.Conclusion: The therapy of orofacial pain in Indonesian sample was proven to be effective. Further study evaluating the reasons underlying the current results is of importance.","PeriodicalId":19786,"journal":{"name":"Pain Research and Treatment","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2018/6078457","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36401373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Liposome Bupivacaine Compared to Plain Local Anesthetics to Reduce Postsurgical Pain: An Updated Meta-Analysis of Randomized Controlled Trials. 脂质体布比卡因与普通局麻药相比减少术后疼痛:一项随机对照试验的最新荟萃分析。

Pain Research and Treatment Pub Date : 2018-07-15 eCollection Date: 2018-01-01 DOI: 10.1155/2018/5710169

Mark C Kendall, Lucas Jorge Castro Alves, Gildasio De Oliveira

{"title":"Liposome Bupivacaine Compared to Plain Local Anesthetics to Reduce Postsurgical Pain: An Updated Meta-Analysis of Randomized Controlled Trials.","authors":"Mark C Kendall, Lucas Jorge Castro Alves, Gildasio De Oliveira","doi":"10.1155/2018/5710169","DOIUrl":"https://doi.org/10.1155/2018/5710169","url":null,"abstract":"Objective: Peripheral nerve blocks for postoperative analgesia have improved block success, but analgesia efficacy has been limited by the short duration of traditional local anesthetics. The results of randomized trials comparing liposome bupivacaine with conventional local anesthetic formulations (e.g., plain bupivacaine and ropivacaine) have generated conflicting results. This study was conducted to systematically review the effectiveness of analgesic efficacy of liposome bupivacaine infiltration at the surgical site versus plain local anesthetic bupivacaine or ropivacaine in patients undergoing surgery.Methods: PRISMA statement guidelines were followed. A search of electronic databases National Library of Medicine's PubMed database, Cochrane Database of Systematic Reviews, Embase, and Google Scholar from January 2012 to September 2017 was performed. Among the 1,612 records identified, 9 randomized controlled trials involving 779 patients were eligible for data extraction and meta-analysis.Results: Liposome bupivacaine did not reduce postsurgical pain at rest compared to plain local anesthetics at 24 and 48 hours after surgery. Moreover, liposome bupivacaine did not reduce postoperative opioid consumption at 24, 48, or 72 hours when compared to plain local anesthetics. Liposome bupivacaine did reduce postoperative nausea when compared to plain local anesthetics (P =<0.3). There was no significant difference in hospital length of stay between study groups, the use of plain bupivacaine or ropivacaine, or among orthopedic or nonorthopedic procedures. No manifestations of local anesthetic toxicity were reported.Conclusions: Our results suggest that liposome bupivacaine does not have an analgesic advantage when compared to plain local anesthetics at the surgical site for patients undergoing surgical procedures.","PeriodicalId":19786,"journal":{"name":"Pain Research and Treatment","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2018/5710169","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36401372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 32

Incidence and Health Related Quality of Life of Opioid-Induced Constipation in Chronic Noncancer Pain Patients: A Prospective Multicentre Cohort Study. 慢性非癌性疼痛患者阿片类药物引起便秘的发生率和健康相关生活质量:一项前瞻性多中心队列研究

Pain Research and Treatment Pub Date : 2018-07-10 eCollection Date: 2018-01-01 DOI: 10.1155/2018/5704627

Dalila R Veiga, Liliane Mendonça, Rute Sampaio, José C Lopes, Luís F Azevedo

{"title":"Incidence and Health Related Quality of Life of Opioid-Induced Constipation in Chronic Noncancer Pain Patients: A Prospective Multicentre Cohort Study.","authors":"Dalila R Veiga, Liliane Mendonça, Rute Sampaio, José C Lopes, Luís F Azevedo","doi":"10.1155/2018/5704627","DOIUrl":"https://doi.org/10.1155/2018/5704627","url":null,"abstract":"Background: High rates of opioid use for chronic noncancer pain (CNCP) have been reported worldwide, despite its association with adverse events, inappropriate use, and limited analgesic effect. Opioid-induced constipation (OIC) is the most prevalent and disabling adverse effect associated with opioid therapy. Our aim was to assess the incidence, health related quality of life (HRQOL), and disability in OIC patients.Methods: A prospective cohort study was performed, with 6 months of follow-up, of adult CNCP patients consecutively admitted in 4 multidisciplinary pain clinics (MPC). Demographic and clinical data have been collected. Brief Pain Inventory (BPI) and Short version of Treatment Outcomes in Pain Survey (S-TOPS) were used to measure functional outcomes and HRQOL. OIC was assessed using Bowel Function Index (BFI).Results: 694 patients were recruited. OIC prevalence at baseline was 25.8%. At 6 months, OIC incidence was 24.8%. Female gender (OR = 1.65, p = 0.039), opioid therapy (OR 1.65, p = 0.026), and interference pain score on BPI (OR 1.10, p = 0.009) were identified as OIC independent predictors. OIC patients presented higher disability and pain interference and severity scores. OIC patients reported less satisfaction with outcome (p = 0.038).Discussion: Constipation is a common adverse event among opioid users with major functional and quality of life impairment. These findings emphasise the need of OIC adequate assessment and management.","PeriodicalId":19786,"journal":{"name":"Pain Research and Treatment","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2018/5704627","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36401371","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 13

Burn Pain Management at Burn Unit of Yekatit 12 Hospitals, Addis Ababa. 亚的斯亚贝巴Yekatit 12医院烧伤科的烧伤疼痛管理。

Pain Research and Treatment Pub Date : 2018-07-04 eCollection Date: 2018-01-01 DOI: 10.1155/2018/1092650

Negashu Dadi Mengistu, Mohammed Suleiman Obsa, Leulayehu Akalu Gemeda

{"title":"Burn Pain Management at Burn Unit of Yekatit 12 Hospitals, Addis Ababa.","authors":"Negashu Dadi Mengistu, Mohammed Suleiman Obsa, Leulayehu Akalu Gemeda","doi":"10.1155/2018/1092650","DOIUrl":"https://doi.org/10.1155/2018/1092650","url":null,"abstract":"Background: Burn pain is a unique and complex challenge for all health professionals and the patients. The only way to insure quality burn pain relief is the patient's self-report. Thus, assessment of severity of pain and its associated factors are important in treatment plan.Objective: To assess severity of burn pain and associated factors in Yekatit 12 Hospitals burn unit from January 1, 2017, to March 30, 2017.Methods: Hospital based cross sectional study design was conducted. Data was collected by using structural questionnaires from all eligible patients, those admitted to burn unit of Yekatit 12 Hospital during the study period. Severity of burn pain was assessed by using numerical, facial, and behavioral pain scale measurement tools. Pain assessment scale was deployed for patients by data collectors before medication and dressing change. Multivariate logistic regression analysis was conducted to identify significant predictors based on p value less than 0.05 with 95% confidence interval.Results: A total of 62 burn patients were included in the study. 87.1% of the patients feel severe pain and 12.9% of the patients feel moderate pain. Pediatrics age groups were about 11 times more likely to feel severe pain than adults, and patients with TBSA ≥ 25% were about 8 times more likely to feel severe burn pain than those with TBSA < 25% [AOR = 7.773; CI 1.184, 51.043] (P = 0.033).Conclusion and recommendation: Majorities of burn patients had severe pain and burn pain was not appropriately treated. Therefore, appropriate pain management was strongly recommended.","PeriodicalId":19786,"journal":{"name":"Pain Research and Treatment","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2018/1092650","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36401370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 8

Sphenopalatine Ganglion Block for the Treatment of Acute Migraine Headache. 蝶腭神经节阻滞治疗急性偏头痛。

Pain Research and Treatment Pub Date : 2018-05-07 eCollection Date: 2018-01-01 DOI: 10.1155/2018/2516953

Mohamed Binfalah, Eman Alghawi, Eslam Shosha, Ali Alhilly, Moiz Bakhiet

{"title":"Sphenopalatine Ganglion Block for the Treatment of Acute Migraine Headache.","authors":"Mohamed Binfalah, Eman Alghawi, Eslam Shosha, Ali Alhilly, Moiz Bakhiet","doi":"10.1155/2018/2516953","DOIUrl":"https://doi.org/10.1155/2018/2516953","url":null,"abstract":"Transnasal sphenopalatine ganglion block is emerging as is an attractive and effective treatment modality for acute migraine headaches, cluster headache, trigeminal neuralgia, and several other conditions. We assessed the efficacy and safety of this treatment using the Sphenocath® device. 55 patients with acute migraine headaches underwent this procedure, receiving 2 ml of 2% lidocaine in each nostril. Pain numeric rating scale (baseline, 15 minutes, 2 hours, and 24 hours) and patient global impression of change (2 hours and 24 hours after treatment) were recorded. The majority of patients became headache-free at 15 minutes, 2 hours, and 24 hours after procedure (70.9%, 78.2%, and 70.4%, resp.). The rate of headache relief (50% or more reduction in headache intensity) was 27.3% at 15 minutes, 20% at 2 hours, and 22.2% at 24 hours. The mean pain numeric rating scale decreased significantly at 15 minutes, 2 hours, and 24 hours, respectively. Most patients rated the results as very good or good. The procedure was well-tolerated with few adverse events. This treatment is emerging as an effective and safe option for management of acute migraine attacks.","PeriodicalId":19786,"journal":{"name":"Pain Research and Treatment","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2018/2516953","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36189338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 52

Prevalence and Characterization of Breakthrough Pain Associated with Chronic Low Back Pain in the South of Spain: A Cross-Sectional, Multicenter, Observational Study. 西班牙南部与慢性腰痛相关的突破性疼痛的患病率和特征:一项横断面、多中心、观察性研究。

Pain Research and Treatment Pub Date : 2018-04-23 eCollection Date: 2018-01-01 DOI: 10.1155/2018/4325271

Luis Miguel Torres, Antonio Javier Jiménez, Ana Cabezón, Manuel Jesús Rodríguez

{"title":"Prevalence and Characterization of Breakthrough Pain Associated with Chronic Low Back Pain in the South of Spain: A Cross-Sectional, Multicenter, Observational Study.","authors":"Luis Miguel Torres, Antonio Javier Jiménez, Ana Cabezón, Manuel Jesús Rodríguez","doi":"10.1155/2018/4325271","DOIUrl":"https://doi.org/10.1155/2018/4325271","url":null,"abstract":"Chronic low back pain (CLBP) is highly prevalent in industrialized countries, where it is one of the main causes of disability. Patients with CLBP in treatment with opioids often experience episodes of breakthrough pain (BTP), but data on prevalence and treatment preferences are scarce. The objectives of this study were, first, the evaluation of the prevalence of BTP in patients with CLBP in the South of Spain (N = 1,868) and, second, the characterization of BTP in these patients (N = 295). Data was collected on presence of BTP, type and location of pain, treatment, compliance, and patient satisfaction. We found a prevalence of BTP in patients with CLBP of 37.5% (95% CI: 35.3%-39.7%), similar in men and women. 75% of the patients were older than 50 years. The preferred drug of patients who control BTP with opioids is fentanyl (78.3%) and its most common form of administration is nasal (53.2%). Therapeutic compliance was high and 46.3% of patients considered the control of their BTP very satisfactory. Our study showed that BTP is common in patients with CLBP and that current treatments seem adequate.","PeriodicalId":19786,"journal":{"name":"Pain Research and Treatment","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2018/4325271","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36177996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0