{"title":"Waiting more than 6 hours from diagnosis does not negatively impact the success rate of pneumatic ileocolic intussusception reduction.","authors":"Gerardo Cruz, Brendon L Graeber","doi":"10.1007/s00247-025-06382-4","DOIUrl":"https://doi.org/10.1007/s00247-025-06382-4","url":null,"abstract":"<p><strong>Background: </strong>Ileocolic intussusception is the most common cause of bowel obstruction in young children. There is an ongoing debate about whether it is a middle-of-the-night emergency and if delays in intervention have a significant impact on outcome.</p><p><strong>Objective: </strong>To determine the relationship between the time elapsed from diagnosis to pneumatic reduction and the success rate of the procedure.</p><p><strong>Materials and methods: </strong>A retrospective study was performed on pediatric patients who underwent fluoroscopically guided pneumatic intussusception reduction during a 10-year period. Patients were categorized into groups according to the time elapsed between diagnosis and reduction with the following time intervals: ≤ 3 h, 3-6 h, and > 6 h. A chi-square test analyzed the association between the time elapsed from diagnosis to attempted reduction and the success rate.</p><p><strong>Results: </strong>The study population consisted of 78 males and 38 females. Median age was 22.5 months (2-129 months). Median time elapsed between diagnosis and attempted reduction was 149 min (25-1389 min; IQR, 261 min). The overall success rate of pneumatic reduction was 85% (108/127, 95% CI 79-91%). The recurrence rate was 9.4% (95% CI 4.2-15%). Within the three intervals studied (0-3 h, 3-6 h, and more than 6 h), the success rates were 87% (61/70, 95% CI 77-93%), 80% (24/30, 95% CI 63-90%), and 85% (23/27, 95% CI 68-94%), respectively. The chi-square test yielded a statistic of 0.84 with a P-value of 0.66, indicating no significant correlation between the time elapsed from diagnosis to reduction and the success of the procedure.</p><p><strong>Conclusion: </strong>There is no association between the time elapsed from ileocolic intussusception diagnosis to pneumatic reduction and the success of the procedure.</p>","PeriodicalId":19755,"journal":{"name":"Pediatric Radiology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145054942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Samal Munidasa, Faiyza Alam, Brandon Zanette, Daniel Li, Wallace Wee, Sharon Braganza, Jason Woods, Felix Ratjen, Giles Santyr
{"title":"Comparison of phase-resolved functional lung (PREFUL) and hyperpolarized <sup>129</sup>Xe MRI for longitudinal monitoring of lung function in pediatric cystic fibrosis following elexacaftor/tezacaftor/ivacaftor.","authors":"Samal Munidasa, Faiyza Alam, Brandon Zanette, Daniel Li, Wallace Wee, Sharon Braganza, Jason Woods, Felix Ratjen, Giles Santyr","doi":"10.1007/s00247-025-06390-4","DOIUrl":"https://doi.org/10.1007/s00247-025-06390-4","url":null,"abstract":"<p><strong>Background: </strong>Phase-resolved functional lung (PREFUL) MRI offers a more accessible alternative to hyperpolarized <sup>129</sup>Xe MRI (Xe-MRI) for monitoring treatment response in pediatric cystic fibrosis (CF), but longitudinal comparisons are limited.</p><p><strong>Objective: </strong>To assess longitudinal lung function changes following elexacaftor/tezacaftor/ivacaftor (ETI) treatment initiation in CF children using PREFUL MRI, in comparison with Xe-MRI and pulmonary function tests (PFTs).</p><p><strong>Materials and methods: </strong>PREFUL MRI, Xe-MRI, and PFTs were performed in 14 CF patients (median [IQR] age 15 [14-16.5] years old) at baseline and 1 month, 6 months, 12 months, and 24 months following initiation of ETI treatment. Ventilation and defect percentage (VDP) was derived from PREFUL MRI (regional ventilation VDP, VDP<sub>RVent</sub>; regional-flow volume loop cross-correlation VDP, VDP<sub>CC</sub>; and the combination of VDP<sub>RVent</sub> and VDP<sub>CC</sub>, VDP<sub>combined</sub>) and Xe-MRI (VDP<sub>Xe</sub>) maps. Perfusion defect percentage (QDP) was derived from normalized perfusion maps and, with VDP<sub>combined</sub>, determined the percentage of healthy ventilation-perfusion matching (VQM). Significance of 1-month treatment changes was determined using the Wilcoxon-signed rank test and was correlated between metrics using Spearman ranked correlation.</p><p><strong>Results: </strong>All PREFUL measures significantly improved (P < 0.01) 1-month post-treatment in agreement with changes in Xe-MRI VDP and PFTs (P < 0.03). The absolute change in VDP<sub>CC</sub> and VDP<sub>combined</sub> significantly correlated with VDP<sub>Xe</sub> (r ≥ 0.62, P < 0.02), unlike VDP<sub>RVent</sub> (P = 0.35). The change in QDP did not correlate with any metric (P > 0.10). PREFUL MRI and Xe-MRI measures showed minimal changes 1 to 24 months post-treatment (median changes = -2.3% to 1.4%), in agreement with PFTs.</p><p><strong>Conclusion: </strong>PREFUL MRI detects longitudinal treatment-related changes in pulmonary ventilation and perfusion in CF children post ETI.</p>","PeriodicalId":19755,"journal":{"name":"Pediatric Radiology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145040760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cara E Morin, Joseph Y Cao, Lindsay M Griffin, Erin B Macdonald, Morgan P McBee, Bruce L McHam, Scott H Robertson, Elizabeth Tang, Gary R Schooler
{"title":"Best practices for pediatric liver MRI: guidelines from members of the Society for Pediatric Radiology Magnetic Resonance and Abdominal Imaging Committees.","authors":"Cara E Morin, Joseph Y Cao, Lindsay M Griffin, Erin B Macdonald, Morgan P McBee, Bruce L McHam, Scott H Robertson, Elizabeth Tang, Gary R Schooler","doi":"10.1007/s00247-025-06383-3","DOIUrl":"https://doi.org/10.1007/s00247-025-06383-3","url":null,"abstract":"<p><p>Magnetic resonance imaging (MRI) has become an essential tool in the evaluation of pediatric liver disease. However, the unique physiological, anatomical, and behavioral characteristics of pediatric patients present distinct challenges that necessitate tailored imaging strategies. These guidelines, developed by members of the Society for Pediatric Radiology (SPR) Magnetic Resonance and Abdominal Imaging Committees, provide comprehensive recommendations for performing high-quality liver MRI in children. Drawing on multidisciplinary expertise from pediatric radiologists, MRI physicists, and technologists across diverse institutions, the document addresses key technical considerations, including field strength selection, motion mitigation, contrast agent use, and age-specific protocol optimization. These guidelines aim to standardize and elevate the quality of pediatric liver MRI, offering practical, evidence-informed recommendations to support safe, efficient, and diagnostically robust imaging across a wide range of clinical scenarios.</p>","PeriodicalId":19755,"journal":{"name":"Pediatric Radiology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145030228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Prenatal diagnosis of cerebellar hypoplasia in fetal ultrasound using deep learning under the constraint of the anatomical structures of the cerebellum and cistern.","authors":"Xiaoxiao Wu, Fu Liu, Guoping Xu, Yiling Ma, Chen Cheng, Ruifan He, Aoxiang Yang, Jiayi Gan, Jiajun Liang, Xinglong Wu, Sheng Zhao","doi":"10.1007/s00247-025-06376-2","DOIUrl":"https://doi.org/10.1007/s00247-025-06376-2","url":null,"abstract":"<p><strong>Objective: </strong>The objective of this retrospective study is to develop and validate an artificial intelligence model constrained by the anatomical structure of the brain with the aim of improving the accuracy of prenatal diagnosis of fetal cerebellar hypoplasia using ultrasound imaging.</p><p><strong>Background: </strong>Fetal central nervous system dysplasia is one of the most prevalent congenital malformations, and cerebellar hypoplasia represents a significant manifestation of this anomaly. Accurate clinical diagnosis is of great importance for the purpose of prenatal screening of fetal health. Although ultrasound has been extensively utilized to assess fetal development, the accurate assessment of cerebellar development remains challenging due to the inherent limitations of ultrasound imaging, including low resolution, artifacts, and acoustic shadowing of the skull.</p><p><strong>Materials and methods: </strong>This retrospective study included 302 cases diagnosed with cerebellar hypoplasia and 549 normal pregnancies collected from Maternal and Child Health Hospital of Hubei Province between September 2019 and September 2023. For each case, experienced ultrasound physicians selected appropriate brain ultrasound images to delineate the boundaries of the skull, cerebellum, and cerebellomedullary cistern. These cases were divided into one training set and two test sets, based on the examination dates. This study then proposed a dual-branch deep learning classification network, anatomical structure-constrained network (ASC-Net), which took ultrasound images and anatomical structure masks as separate inputs. The performance of the ASC-Net was extensively evaluated and compared with several state-of-the-art deep learning networks. The impact of anatomical structures on the performance of ASC-Net was carefully examined.</p><p><strong>Results: </strong>ASC-Net demonstrated superior performance in the diagnosis of cerebellar hypoplasia, achieving classification accuracies of 0.9778 and 0.9222, as well as areas under the receiver operating characteristic curve of 0.9986 and 0.9265 on the two test sets. These results significantly outperformed several state-of-the-art networks on the same dataset. In comparison to other studies on cerebellar hypoplasia auxiliary diagnosis, ASC-Net also demonstrated comparable or even better performance. A subgroup analysis revealed that ASC-Net was more capable of distinguishing cerebellar hypoplasia in cases with gestational weeks greater than 30 weeks. Furthermore, when constrained by anatomical structures of both the cerebellum and cistern, ASC-Net exhibited the best performance compared to other kinds of structural constraint.</p><p><strong>Conclusions: </strong>The development and validation of ASC-Net have significantly enhanced the accuracy of prenatal diagnosis of cerebellar hypoplasia using ultrasound images. This study highlights the importance of anatomical structures of the fetal cerebellum a","PeriodicalId":19755,"journal":{"name":"Pediatric Radiology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145001051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gladys M Arguello Fletes, Wei Zhou, LaDonna J Malone, Andrea I Fuentealba Cargill, Jason P Weinman, Lorna P Browne
{"title":"Comparative radiation dose analysis in pediatric high-pitch cardiac CTA using photon-counting versus energy-integrating detector CT.","authors":"Gladys M Arguello Fletes, Wei Zhou, LaDonna J Malone, Andrea I Fuentealba Cargill, Jason P Weinman, Lorna P Browne","doi":"10.1007/s00247-025-06336-w","DOIUrl":"https://doi.org/10.1007/s00247-025-06336-w","url":null,"abstract":"<p><strong>Background: </strong>Previous studies have shown improved image quality in pediatric cardiac imaging using photon-counting detector CT (PCDCT). However, these studies did not evaluate image quality and radiation dose when utilizing the full spectral capabilities of PCDCT scanners. The full spectral capability of PCDCT scanners allows the generation of the entire array of mono-energetic reconstructions, virtual non-contrast (VNC) images, and iodine maps, which have potential advantages in evaluating complex congenital heart disease. For example, following complex congenital cardiac repairs, when distinguishing intraluminal or soft tissue calcifications from contrast, or when evaluating intrastent thrombus.</p><p><strong>Objective: </strong>To compare image quality and radiation dose between high-pitch cardiac CT using full spectral PCDCT and dual-source energy-integrating detector CT (EIDCT).</p><p><strong>Materials and methods: </strong>This retrospective, IRB-approved study analyzed high-pitch cardiac CTs from January 2021 to October 2023 in pediatric patients (< 18 years). Patients were scanned using either PCDCT with full spectral technique (\"QuantumPlus\") or EIDCT. Radiation doses were measured by CT dose index (CTDI) and dose-length product (DLP). Signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) were also calculated, and image quality was assessed using a 5-point Likert scale. Statistical analysis included unpaired T-test, Shapiro-Wilk test, Mann-Whitney test, and kappa coefficients for interrater agreement.</p><p><strong>Results: </strong>Two hundred patients were evaluated, with 100 scanned on PCDCT and 100 on EIDCT. In the PCDCT scanner, 47/100 (47%) were male and 53/100 were female (53%) (P = 0.01). In the EIDCT scanner, 65/100 were male (65%) and 35/100 (35%) were female (P = 0.01). In the PCDCT scanner, 68/100 (68%) (P = 0.05) were ≤ 12 months, and 32/100 (32%) (P = 0.05) were > 12 months. In the EIDCT, 80/100 (80%) (P = 0.05) were ≤ 12 months, and 20/100 (20%) (P = 0.05) were > 12 months. In patients ≤ 12 months, the CNR were 31.61 in the PCDCT group and 32.14 in the EIDCT group (P = 0.39). For those > 12 months, CNR were 30.07 for PCDCT and 25.27 for EIDCT (P = 0.17). In patients ≤ 12 months, SNR was significantly lower (P < 0.0001) in PCDCT, compared to EIDCT for the teres minor muscles, while in patients > 12 months, SNR was not significantly lower (P = 0.89); SNR was similar between scanners. Radiation doses were significantly higher for PCDCT across both age groups (P < 0.0001).</p><p><strong>Conclusion: </strong>High-pitch cardiac CT with PCDCT using spectral processing resulted in higher radiation doses and lower SNR in infants compared to EIDCT.</p>","PeriodicalId":19755,"journal":{"name":"Pediatric Radiology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145001054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mariama Lukulay, Pradipta Debnath, Christopher G Anton, Yinan Li, Adam F Prasanphanich, Susan E Sharp, Bin Zhang, Andrew T Trout, Cara E Morin
{"title":"Does the addition of fentanyl premedication impact brown fat uptake in children undergoing a warming protocol for FDG PET?","authors":"Mariama Lukulay, Pradipta Debnath, Christopher G Anton, Yinan Li, Adam F Prasanphanich, Susan E Sharp, Bin Zhang, Andrew T Trout, Cara E Morin","doi":"10.1007/s00247-025-06381-5","DOIUrl":"https://doi.org/10.1007/s00247-025-06381-5","url":null,"abstract":"<p><strong>Background: </strong>Fentanyl is used in some pediatric practices with a goal of suppressing 18F-fluorodeoxyglucose (18F-FDG) uptake in brown fat.</p><p><strong>Objective: </strong>The purpose of this study was to examine the frequency, intensity, and distribution of brown fat uptake in warmed children undergoing 18F-FDG PET/CT with and without premedication with fentanyl. MATERIALS AND METHODS: This retrospective study included children (< 18 years old) who underwent 18F-FDG-PET from 2014 to 2024 at a center that routinely warms patients and uses intravenous fentanyl for brown fat suppression for most patients. Three radiologists assessed the presence, intensity, and location of brown fat uptake. Chi-square test and two-sample t-test were used to compare the demographics and brown fat uptake between premedication and non-premedication groups.</p><p><strong>Results: </strong>Among 873 18F-FDG-PETs, 595 (68%) were performed with fentanyl premedication and warming and 278 (32%) were conducted with warming alone. Brown fat uptake was observed in 46 (5.3%) FDG-PETs, 32/595 (5.4%) in the premedicated group and 14/278 (5.0%) in the non-premedicated group (P = 0.83). No differences were found in brown fat intensity or location based on premedication status. Age (14.5 vs. 8.5; P < 0.001) and BMI (20.1 vs. 17.7; P < 0.001) were significantly associated with brown fat uptake.</p><p><strong>Conclusion: </strong>Fentanyl premedication does not significantly affect brown fat uptake frequency, intensity, or location in warmed children undergoing 18F-FDG-PET.</p>","PeriodicalId":19755,"journal":{"name":"Pediatric Radiology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144992652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Siddig Ibrahim Abdelwahab, Manal Mohamed Elhassan Taha, Abdullah Farasani, Jobran M Moshi, Abrar Fahad Alshahrani, Ahmad Assiri, Saeed Alshahrani, Muhammad H Sultan, Khaled A Sahli, Hussam M Shubaily, Omer Ahmed Elrhima, Waseem Hassan
{"title":"Tracing global inequities in radiology research: a multi-level analysis of research output.","authors":"Siddig Ibrahim Abdelwahab, Manal Mohamed Elhassan Taha, Abdullah Farasani, Jobran M Moshi, Abrar Fahad Alshahrani, Ahmad Assiri, Saeed Alshahrani, Muhammad H Sultan, Khaled A Sahli, Hussam M Shubaily, Omer Ahmed Elrhima, Waseem Hassan","doi":"10.1007/s00247-025-06388-y","DOIUrl":"https://doi.org/10.1007/s00247-025-06388-y","url":null,"abstract":"<p><strong>Background: </strong>Authorship disparities in medical research are evident, particularly between high-income countries (HICs) and low- and middle-income countries (LICs/LMICs). These disparities have been analyzed in recent publications in Pediatric Radiology journal, noting that between 2019 and 2022, no manuscripts from LICs and only 13 manuscripts from LMICs were published. To our knowledge, an extensive review of publication trends in Pediatric Radiology journal and in radiology word containing journals, with regard to LICs/LMICs disparities, is currently lacking.</p><p><strong>Objective: </strong>The objective was to assess historical trends and regional disparities in radiology research output and impact.</p><p><strong>Materials and methods: </strong>A three-pronged approach was used: (1) analysis of all original articles and reviews in Pediatric Radiology (1973-2024), distinguishing LMIC contributions with or without collaboration; (2) broader review of all Scopus-indexed journals with \"radiology*\" in the title (2001-2024), focusing on LMIC authorship; (3) comprehensive assessment of all Scopus-classified \"Radiology, Nuclear Medicine and Imaging\" publications (2021-2024), including output and citation data from 187 countries and various global regions.</p><p><strong>Results: </strong>In Pediatric Radiology, only 3.4% of the 8,907 articles involved LMIC collaborations, and 0.9% were authored by LMIC researchers. The number of annual independent LMIC contributions never exceeded 5 until recently. In journals containing \"radiology\" in the title, LMIC researchers contributed 2.3% of all articles through collaboration and 1.25% independently, with 2024 data revealing continued reliance on partnerships (476 collaborative vs. 276 independent LMIC articles). The USA contributed 53,474 publications (26.67%) and received 362,681 citations (33.75%), whereas China produced 44,851 publications (22.37%) with 237,884 citations (22.14%). Africa produced 4,375 publications and received 22,161 citations, Latin America contributed 4,150 publications with 30,061 citations, and South America generated 3,590 publications with 26,084 citations. The Middle East had the highest citation-per-publication ratio (6.1), followed by the Asia Pacific (5.7), the Organization of Islamic Cooperation (5.3), South Asia (5.2), and Africa (5.1).</p><p><strong>Conclusion: </strong>The data illustrate that LMICs remain underrepresented in radiology research. Targeted policy reforms, funding mechanisms, and capacity-building strategies are needed to enhance equity and support LMIC-driven radiology scholarship.</p>","PeriodicalId":19755,"journal":{"name":"Pediatric Radiology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144963974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Parietal intradiploic arachnoid diverticulum: A rare delayed complication of endoscopic third ventriculostomy.","authors":"Lukshay Bansal, Akhila Prasad, Supriya Kaur","doi":"10.1007/s00247-025-06387-z","DOIUrl":"https://doi.org/10.1007/s00247-025-06387-z","url":null,"abstract":"<p><p>A postoperative intradiploic arachnoid diverticulum secondary to endoscopic third ventriculostomy is an extremely rare occurrence. It has a varied clinical presentation and is caused by the insinuation of the arachnoid through the dural rent into the intradiploic compartment following the procedure. This case report describes an incidentally diagnosed right parietal intradiploic arachnoid diverticulum as a complication of endoscopic third ventriculostomy. Skull radiography revealed an expansion of the right parietal bone with an intact outer table. Non-contrast computed tomography showed a well-defined cystic lesion in the intradiploic compartment, accompanied by expansion of the right parietal bone. A subsequent magnetic resonance imaging distinguished it from an epidermoid cyst. Knowledge of this rare entity is cardinal for early diagnosis and management, required to prevent potential neurological sequelae.</p>","PeriodicalId":19755,"journal":{"name":"Pediatric Radiology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144963993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}