Paediatrics & child health最新文献_第6页

Kawasaki disease: practical guidance on diagnosis and management. 川崎病：诊断和治疗的实用指南。

IF 2.5 4区医学

Paediatrics & child health Pub Date : 2026-03-28 eCollection Date: 2026-07-01 DOI: 10.1093/pch/pxag014

Audrea Chen, Evelyn Rozenblyum, Nagib Dahdah, Bianca Lang, Rosie Scuccimarri, Piya Lahiry, Herman Tam, Mercedes Chan, Andrea Human, Jennifer Lee, Peter Wong, Paul Tsoukas, Rae S M Yeung

引用次数: 0

Proteinuria and gall bladder wall thickness as predictive indicators for dengue severity in pediatric patients. 蛋白尿和胆囊壁厚度作为儿科患者登革热严重程度的预测指标。

IF 2 4区医学

Paediatrics & child health Pub Date : 2026-03-27 eCollection Date: 2026-06-01 DOI: 10.1093/pch/pxag009

N Namratha, Manish Narang, Rahul Sharma, Nishant Raizada, Anju Aggarwal, Shuchi Bhatt

{"title":"Proteinuria and gall bladder wall thickness as predictive indicators for dengue severity in pediatric patients.","authors":"N Namratha, Manish Narang, Rahul Sharma, Nishant Raizada, Anju Aggarwal, Shuchi Bhatt","doi":"10.1093/pch/pxag009","DOIUrl":"https://doi.org/10.1093/pch/pxag009","url":null,"abstract":"Objectives: Dengue is a mosquito-borne viral illness affecting children and can progress to severe forms with capillary leakage, bleeding and organ dysfunction. Early detection is crucial to reduce complications. This study evaluated the predictive value of 2 noninvasive markers, urine albumin-creatinine ratio (UACR) and gall bladder wall thickness (GBWT) for disease severity in pediatric dengue.Methods: A prospective observational study was conducted from May 2023 to November 2024 at a tertiary care hospital in Northern India. Children aged 6 months to 12 years with moderate to severe dengue (WHO 2009 classification) were included. UACR was measured from spot urine samples at admission, during deterioration or at discharge. GBWT was assessed via abdominal ultrasound between days 3 and 6 of fever. Associations with disease severity, laboratory parameters, and mortality outcomes were analyzed.Results: Among 74 participants, mean UACR (mg/g) was significantly higher in severe dengue compared to moderate cases (136.31 [151.26] vs. 44.87 [59.77]; P < 0.001), with elevated UACR linked to higher mortality. Mean GBWT (mm) was significantly greater in severe dengue (7.35 [2.25] vs. 5.11 [2.49]; P = 0.035), correlating with poor outcomes. Sensitivity and specificity of UACR (cutoff 30 mg/g) were 62% and 60%, and GBWT at 5 mm were 81% and 60%. Odds ratios for severe dengue were 3.9 (UACR), 10.7 (GBWT) and 13.3 (both). Honeycomb GBWT patterns were more frequent in fatal cases.Conclusion: UACR and GBWT, while not definitive alone, are noninvasive adjuncts for predicting severity and mortality in pediatric dengue, supporting early identification, triage and management.","PeriodicalId":19730,"journal":{"name":"Paediatrics & child health","volume":"31 4","pages":"360-366"},"PeriodicalIF":2.0,"publicationDate":"2026-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13245163/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148211865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

When the body speaks: managing somatic symptoms in the paediatric emergency department. 当身体说话：在儿科急诊科处理躯体症状。

IF 2 4区医学

Paediatrics & child health Pub Date : 2026-03-19 eCollection Date: 2026-06-01 DOI: 10.1093/pch/pxag006

Natasha R Saunders

引用次数: 0

Juvenile recurrent parotitis: a paediatric rheumatology perspective. 青少年复发性腮腺炎：儿科风湿病学的观点。

IF 2 4区医学

Paediatrics & child health Pub Date : 2026-03-19 eCollection Date: 2026-06-01 DOI: 10.1093/pch/pxag002

Didem Öztürk, Elif Çelikel, Zahide Ekici Tekin, Cüneyt Karagöl, Şeyma Ertem, Merve Cansu Polat, Emine Özçelik, Mehveş Işıklar Ekici, Yasemin Uğur Es, Sultan Nilay Yoğun, Şeyma Erdem Torun, Aslınur Özkaya Parlakay, Avni Merter Keçeli, Banu Acar

{"title":"Juvenile recurrent parotitis: a paediatric rheumatology perspective.","authors":"Didem Öztürk, Elif Çelikel, Zahide Ekici Tekin, Cüneyt Karagöl, Şeyma Ertem, Merve Cansu Polat, Emine Özçelik, Mehveş Işıklar Ekici, Yasemin Uğur Es, Sultan Nilay Yoğun, Şeyma Erdem Torun, Aslınur Özkaya Parlakay, Avni Merter Keçeli, Banu Acar","doi":"10.1093/pch/pxag002","DOIUrl":"https://doi.org/10.1093/pch/pxag002","url":null,"abstract":"Objective: The purpose of this study was to evaluate the demographic characteristics, clinical and laboratory findings, imaging methods and treatment of juvenile recurrent parotitis (JRP) patients.Method: This observational medical record study was conducted in patients, aged 1 to18 years, were diagnosed with JRP.Results: Of the 46 patients with JRP included, 27 (58.7%) were male. The median age at onset was 4 years, and the median age at diagnosis was 6.5 years. Thirty-seven (80.4%) of JRP patients were idiopathic. The underlying causes were as follow: inborn errors of immunity (n = 3, 6.5%), rheumatologic (n = 2, 4.3%), infectious diseases (n = 2, 4.3%), congenital anomaly (n = 431, 2.2%), and one patient (2.2%) had both rheumatologic disease and inborn errors of immunity. Two patients (4.3%) were diagnosed with Sjögren syndrome, and one patient (2.2%) was diagnosed with IgG4-related disease.Conclusion: Although most JRP is idiopathic, some patients may have infectious, structural, immunologic or autoimmune abnormalities.","PeriodicalId":19730,"journal":{"name":"Paediatrics & child health","volume":"31 4","pages":"340-346"},"PeriodicalIF":2.0,"publicationDate":"2026-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13245176/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148212085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Complications of tympanostomy tubes in patients with cleft palate. 腭裂患者鼓室造瘘管的并发症。

IF 2.5 4区医学

Paediatrics & child health Pub Date : 2026-03-19 eCollection Date: 2026-06-01 DOI: 10.1093/pch/pxag005

Jadin Chahade, Kienan Williams, Amy Callaghan, André Isaac

{"title":"Complications of tympanostomy tubes in patients with cleft palate.","authors":"Jadin Chahade, Kienan Williams, Amy Callaghan, André Isaac","doi":"10.1093/pch/pxag005","DOIUrl":"10.1093/pch/pxag005","url":null,"abstract":"Objectives: The primary objective was to determine the prevalence of complications after tympanostomy tube insertion among patients with a cleft palate. The secondary objective was to assess whether patients registered to noninsured health benefits (NIHBs) (all of whom are Indigenous) experience different risk of these complications than patients not registered to NIHB.Methods: This retrospective cohort study included paediatric patients (<18 years) treated at a tertiary otolaryngology referral centre serving a large population of Indigenous Peoples, including a subset registered to the NIHB. Patients with cleft palate who underwent tympanostomy tube insertion and had at least 12 months of follow-up with pre- and postoperative audiograms were included. Primary outcomes were the prevalence of tube-related complications and the rate of repeat tympanostomy tube insertions.Results: A total of 278 patients met inclusion criteria. The median age at tube insertion was 12 months. Of these, 141 (51%) were male, and 30 (11%) were registered to NIHB. The complication rate was 21% (n = 59), with refractory otorrhea being the most common complication (n = 50, 18%). Repeat tympanostomy tubes were required in 116 patients (42%), and 33 patients (12%) required more than 2 sets of tubes. Patients registered to NIHB were significantly more likely to experience complications and have persistent hearing loss on postoperative audiogram but were not more likely to receive repeat tympanostomy tubes.Conclusion: Patients registered to NIHB were disproportionately affected compared with patients not registered to NIHB, and despite being at higher risk for complications, they were not more likely to have repeat procedures.","PeriodicalId":19730,"journal":{"name":"Paediatrics & child health","volume":"31 4","pages":"354-359"},"PeriodicalIF":2.5,"publicationDate":"2026-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13245181/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148212112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Streamlining Kawasaki disease care: a quality improvement initiative to safely reduce length of stay. 流线型川崎病护理：质量改进倡议，以安全减少住院时间。

IF 2.5 4区医学

Paediatrics & child health Pub Date : 2026-03-17 eCollection Date: 2026-06-01 DOI: 10.1093/pch/pxag001

Audrea Chen, Beth D Gamulka, Hanof Alkhdher, Macarena Palomer, Rae S M Yeung

{"title":"Streamlining Kawasaki disease care: a quality improvement initiative to safely reduce length of stay.","authors":"Audrea Chen, Beth D Gamulka, Hanof Alkhdher, Macarena Palomer, Rae S M Yeung","doi":"10.1093/pch/pxag001","DOIUrl":"10.1093/pch/pxag001","url":null,"abstract":"Objectives: Kawasaki Disease is the most common cause of paediatric acquired heart disease and one of the most resource-intensive acute paediatric conditions to treat. Hospitalization for Kawasaki Disease is a stressful event for children and caregivers, leading to increased use of emergency resources after resolution of disease. A quality improvement clinical pathway was introduced to alleviate strain on inpatient resources and reduce length of stay by 33% over 12 months.Methods: All patients diagnosed and treated for Kawasaki Disease at this institution were included. The primary outcome measure was length of stay. Patients with complicated Kawasaki Disease (i.e., Admission to intensive care) were excluded from outcome measurement, however process and balancing measures were collected for all patients. Balancing measures included rate of urgent care access post-discharge and patient satisfaction.Results: Forty-nine patients were included in the study, with length of stay data collected for 19. The average length of stay was 46 hours (17% reduction from a pre-intervention baseline of 55 hours). Process measures showed >75% uptake in change ideas following two plan, do, study, act (PDSA) cycles. Patient satisfaction was high with no safety concerns after discharge. Approximately $25,402 was saved over 49 admissions through reductions in length of stay and laboratory investigations.Conclusion: While the primary objective was not met, a sustained 17% reduction in length of stay was achieved without compromising patient safety or satisfaction. This initiative successfully implemented a standardized clinical pathway through strong collaborator engagement and patient-driven change ideas.","PeriodicalId":19730,"journal":{"name":"Paediatrics & child health","volume":"31 4","pages":"319-325"},"PeriodicalIF":2.5,"publicationDate":"2026-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13245165/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148211802","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Improvement of newly diagnosed immune thrombocytopenia management in children by implementing revised practice guidelines. 通过实施修订的实践指南改善儿童新诊断的免疫性血小板减少症的管理。

IF 2 4区医学

Paediatrics & child health Pub Date : 2026-03-13 eCollection Date: 2026-06-01 DOI: 10.1093/pch/pxaf126

Cléo Hautefeuille, Myriam Coté, Brigitte Parisien, Evelyne D Trottier, Yves D Pastore, Thomas Pincez

{"title":"Improvement of newly diagnosed immune thrombocytopenia management in children by implementing revised practice guidelines.","authors":"Cléo Hautefeuille, Myriam Coté, Brigitte Parisien, Evelyne D Trottier, Yves D Pastore, Thomas Pincez","doi":"10.1093/pch/pxaf126","DOIUrl":"https://doi.org/10.1093/pch/pxaf126","url":null,"abstract":"Objectives: Newly diagnosed immune thrombocytopenia is typically transient, with severe bleeding rarely occurring despite low platelet counts. In the absence of significant bleeding, observation without treatment is considered safe in children. Despite guidelines prioritizing bleeding scores over platelet counts to guide treatment decisions, this practice is not widely adopted. The safety and benefit of modifying local practices to follow these guidelines remain unclear. The objective was to describe treatment and hospitalization rates after guideline implementation and to assess the occurrence of complications and persistent immune thrombocytopenia in the POST group compared with the PRE group.Methods: The new algorithm recommended treatment for patients with Buchanan score ≥3 regardless of platelet count, while the previous one suggested treatment if platelet count <10 × 109/L. We compared patient management before (PRE: January 2019-December 2020) and after (POST: January 2022-December 2023) implementation of new local guidelines in the paediatric emergency department of Hospital Sainte-Justine, Quebec.Results: We included 84 patients: 34 PRE and 50 POST with comparable characteristics. In the POST period, the guideline was followed in 88% of the cases, more patients were observed without treatment (PRE 24%, POST 58% P = 0.002) and less were hospitalized at diagnosis (PRE 62%, POST 22% P = 0.0005). The effect was mainly due to a higher observation rate in patients with low bleeding score (PRE 32%, POST 84%). No intracranial bleeding, death, or increased persistent ITP rate was observed.Conclusion: In sum, transitioning from platelet-based to bleeding score based guidelines was safe, reduced treatment use in the emergency department, and decreased hospitalizations.","PeriodicalId":19730,"journal":{"name":"Paediatrics & child health","volume":"31 4","pages":"333-339"},"PeriodicalIF":2.0,"publicationDate":"2026-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13245183/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148212089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

La Loi 79 et la vérité pour les enfants autochtones disparus ou décédés : enjeux pour la pédiatrie et le devoir de mémoire. 第79号法案和失踪或死亡土著儿童的真相：儿科的问题和纪念的责任。

IF 2 4区医学

Paediatrics & child health Pub Date : 2026-03-13 eCollection Date: 2026-06-01 DOI: 10.1093/pch/pxaf135

Claude Cyr, Apolline Coën

引用次数: 0

Bill 79 and the search for truth for missing or deceased Indigenous children: Implications for paediatricians and the duty of memory. 第79号法案和寻找失踪或死亡土著儿童的真相：对儿科医生的影响和记忆义务。

IF 2 4区医学

Paediatrics & child health Pub Date : 2026-03-13 eCollection Date: 2026-06-01 DOI: 10.1093/pch/pxaf137

Claude Cyr, Apolline Coën

引用次数: 0

Les soins aux enfants et aux adolescents touchés par les conflits armés: une approche reposant sur les droits. 照顾受武装冲突影响的儿童和青年：以权利为基础的办法。

IF 2 4区医学

Paediatrics & child health Pub Date : 2026-03-09 eCollection Date: 2026-04-01 DOI: 10.1093/pch/pxaf131

Shazeen Suleman, Charles Hui, Ripudaman Minhas, Ashley Vandermorris

{"title":"Les soins aux enfants et aux adolescents touchés par les conflits armés: une approche reposant sur les droits.","authors":"Shazeen Suleman, Charles Hui, Ripudaman Minhas, Ashley Vandermorris","doi":"10.1093/pch/pxaf131","DOIUrl":"https://doi.org/10.1093/pch/pxaf131","url":null,"abstract":"Les professionnels de la santé qui comprennent les effets des conflits armés sur les enfants et les adolescents en temps de guerre peuvent accorder aux nouveaux arrivants le temps et la latitude nécessaires pour examiner et évaluer les expositions particulières et les besoins de santé des familles et des nouveaux arrivants au Canada. Le présent document de principes traite des effets directs, indirects et éloignés des conflits armés sur les personnes démesurément touchées par la violence, les perturbations et les déplacements. Les jeunes dont les structures scolaires, sanitaires et sociales sont gravement compromises ou ont été détruites à cause des conflits armés subissent souvent d'énormes lacunes en matière d'accès aux soins et vivent depuis longtemps avec des besoins de santé physique et mentale non satisfaits. D'après les obligations du Canada en vertu de la Convention des Nations Unies relative aux droits de l'enfant, le présent document de principes contient des stratégies et des ressources que les professionnels de la santé peuvent utiliser pour mieux reconnaître et comprendre que les effets des conflits armés et des expériences de migration font partie des soins de qualité essentiels et qu'il faut s'y attaquer.","PeriodicalId":19730,"journal":{"name":"Paediatrics & child health","volume":"31 3","pages":"250-257"},"PeriodicalIF":2.0,"publicationDate":"2026-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13079082/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147699178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0