Orbital: The Electronic Journal of Chemistry最新文献_第5页

Chemistry of Pre-exposure Prophylaxis (PrEP) and Brazil’s Protagonism in the Fight Against HIV/AIDS: Exploring the Theme with High School Seniors 接触前预防(PrEP)的化学作用和巴西在抗击艾滋病毒/艾滋病中的主导作用:与高中毕业生探讨这一主题

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Orbital: The Electronic Journal of Chemistry Pub Date : 2023-04-13 DOI: 10.17807/orbital.v15i1.18047

Mateus Ladeira, M. Miranda

{"title":"Chemistry of Pre-exposure Prophylaxis (PrEP) and Brazil’s Protagonism in the Fight Against HIV/AIDS: Exploring the Theme with High School Seniors","authors":"Mateus Ladeira, M. Miranda","doi":"10.17807/orbital.v15i1.18047","DOIUrl":"https://doi.org/10.17807/orbital.v15i1.18047","url":null,"abstract":"The Pre-exposure Prophylaxis (PrEP) for the prevention of human immunodeficiency virus (HIV) infection consists in using antiretroviral medicine before sexual exposure to the virus to decrease probability of infection. The PrEP is capable of preventing the virus infection and promoting a healthier sexual life. Brazil has been a reference in HIV treatment not only because it was the first country in Latin America to offer free antiretroviral treatment to virus carriers but also because it participated in the Initiative in Pre-exposure Prophylaxis (iPrEP), a study that was carried out in several countries worldwide and proved effectiveness of the PrEP. Medication distributed by the Brazilian Public Health System (SUS) is quite unknown to the population. To mitigate current proliferation of sexually transmitted diseases (STDs) and increase in pregnancy cases among adolescents, sexual orientation has been intensified in schools and, thus, it has also become their responsibility, rather than parents’ responsibility alone. Therefore, this study aimed at carrying out dynamic and dialogic interventions about the PrEP in classes taught to High School seniors who attend technical courses in Commerce and in Development of Digital Games at the Instituto Federal do Triângulo Mineiro - Campus Uberlândia Centro, Uberlândia, Minas Gerais (MG), Brazil. A dialogical Chemistry class was taught to show students several images and chemical structures of active ingredients found in the medication (PrEP). Besides, students answered a questionnaire with open questions anonymously to evaluate the effect of the class on their learning about sexual education, HIV/AIDS and, mainly, the PrEP. Students showed much interest in the tasks and interacted positively. Results of the questionnaire enabled to observe students’ increase in knowledge about the PrEP. In sum, this study enabled the PrEP to be better disseminated, since doubts were mitigated.","PeriodicalId":19680,"journal":{"name":"Orbital: The Electronic Journal of Chemistry","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2023-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47057396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Optimization of Hydrophobic Coating Production by Pechini Method on Modified Aluminum Surface 改性铝表面Pechini法制备疏水涂层的优化研究

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Orbital: The Electronic Journal of Chemistry Pub Date : 2023-04-12 DOI: 10.17807/orbital.v15i1.17992

Ariane Aparecida de Lima, Lucas Aparecido Bittencourt, Guilherme José Turcatel Alves, G. Tractz, P. Rodrigues, Cynthia Beatriz Fürstenberger

引用次数: 0

Advancement of Novel Graphene Oxide Embedded Alumina Nickel Composite Coating Developed at Various Current Densities to Evaluate Corrosion Resistance 在不同电流密度下开发的新型氧化石墨烯嵌入氧化铝-镍复合涂层的研究进展

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Orbital: The Electronic Journal of Chemistry Pub Date : 2023-04-12 DOI: 10.17807/orbital.v15i1.17525

U. Pandey, C. Sharma

{"title":"Advancement of Novel Graphene Oxide Embedded Alumina Nickel Composite Coating Developed at Various Current Densities to Evaluate Corrosion Resistance","authors":"U. Pandey, C. Sharma","doi":"10.17807/orbital.v15i1.17525","DOIUrl":"https://doi.org/10.17807/orbital.v15i1.17525","url":null,"abstract":"In this research, the influence of deposition current density on the properties of nickel-Graphene oxide/alumina coatings produced by electrodeposition was examined. Nickel matrix composite coatings with graphene oxide doped Alumina (GO-Al2O3) particles were prepared via electrodeposition. When embedding GO-Al2O3 particles in the Ni matrix, remarkable anti-corrosion properties are anticipated due to the outstanding mechanical properties of GO and Al2O3. The structure, content, and morphology of GO, GO-Al2O3, and coatings deposited at various current densities were determined using X-ray diffraction, Fourier transforms infrared spectroscopy, Field emission Scanning electron microscopy, and energy-dispersive X-ray spectroscopy. GO-doped alumina particles were successfully incorporated into the matrix of nickel, according to the findings. Porosity measurement and cross-sectional thickness were also investigated at various current densities. Potentiodynamic polarization testing and electrochemical impedance spectroscopy were used to study the coatings' corrosion-resistant characteristics. According to the findings, coatings developed at high current densities, such as 30 mA cm-2, are porous and not uniform in nature. Furthermore, at high current densities, the content of GO and Alumina is reduced, resulting in a decrease in mechanical and corrosion resistance. Due to its less porous and uniformly formed coating, 10 mA cm-2 was the optimum current density for achieving the most desirable features. \u0000 ","PeriodicalId":19680,"journal":{"name":"Orbital: The Electronic Journal of Chemistry","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2023-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43813660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Investigation of Neolamarckia cadamba phytoconstituents against SARS-CoV-2 3CL Pro: An In-Silico Approach 新木耳植物成分抗sars - cov - 23cl Pro的实验研究

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Orbital: The Electronic Journal of Chemistry Pub Date : 2023-04-12 DOI: 10.17807/orbital.v15i1.17592

S. Arora, Kalpana Tirpude, Pallavi Rushiya, Nidhi Sapkal, Subhash Yende, Abhay Ittadwar, Sapan Shah

{"title":"Investigation of Neolamarckia cadamba phytoconstituents against SARS-CoV-2 3CL Pro: An In-Silico Approach","authors":"S. Arora, Kalpana Tirpude, Pallavi Rushiya, Nidhi Sapkal, Subhash Yende, Abhay Ittadwar, Sapan Shah","doi":"10.17807/orbital.v15i1.17592","DOIUrl":"https://doi.org/10.17807/orbital.v15i1.17592","url":null,"abstract":"In present study, the inhibitory potential of Neolamarckia cadamba phytoconstituents was investigated against SARS-CoV-2 3CL protease (3CL pro) (PDB ID: 6M2N). Molecular docking was analyzed using AutoDock Vina software by setting the grid parameter as X= -33.163, Y= -65.074 and Z= 41.434 with dimensions of the grid box 25 × 25 × 25 Å. Remdesivir was taken as the standard for comparative analysis along with inhibitor 5, 6, 7-trihydroxy-2-phenyl-4H-chromen-4-one. Furthermore, the exploration of 2 D Hydrogen-bond interactions was performed by Biovia Discovery Studio 4.5 program to identify the interactions between an amino acid of target and ligand followed by assessment of physicochemical properties using Lipinski’s rule and Swiss ADME database. The decent bonding scores of secondary metabolites owing to hydrogen bonding with catalytic residues suggest the effectiveness of these phytochemicals towards 3CLpro. The results are further consolidated positively by Lipinski’s rule and Swiss ADME prediction. Thus reasonably, observations with docking studies suggest possibility of phytochemicals from Neolamarckia cadamba to inhibit the 3CLpro and consequently would be explored further as agents for preventing COVID-19.","PeriodicalId":19680,"journal":{"name":"Orbital: The Electronic Journal of Chemistry","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2023-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67424815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Theoretical Description for Psilocin Electrochemical Determination over Cobalt Oxyhydroxide 羟基氧化钴电化学测定水杨酸的理论描述

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Orbital: The Electronic Journal of Chemistry Pub Date : 2023-04-06 DOI: 10.17807/orbital.v15i1.18012

Volodymyr Tkach, M. Kucher, M. Kushnir, Y. Ivanushko, Y. Akinay, Necdet Karakoyun, P. Yagodynets, Z. Kormosh

引用次数: 0

Cytotoxic Activity of Baccharis trimera (Less.) DC. Essential Oil in Tumor Cell Lines and its Role in Associated Death Mechanisms 三体酒的细胞毒活性(略)直流。精油在肿瘤细胞系中的作用及其在相关死亡机制中的作用

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Orbital: The Electronic Journal of Chemistry Pub Date : 2023-04-06 DOI: 10.17807/orbital.v15i1.17021

I. Moro, F. A. Carvalho, Thais Fernanda Moreira, Felipe de Oliveira Souza, Alexander Alves da Silva, F. Politi, C. P. Soares, A. G. Santos

{"title":"Cytotoxic Activity of Baccharis trimera (Less.) DC. Essential Oil in Tumor Cell Lines and its Role in Associated Death Mechanisms","authors":"I. Moro, F. A. Carvalho, Thais Fernanda Moreira, Felipe de Oliveira Souza, Alexander Alves da Silva, F. Politi, C. P. Soares, A. G. Santos","doi":"10.17807/orbital.v15i1.17021","DOIUrl":"https://doi.org/10.17807/orbital.v15i1.17021","url":null,"abstract":"This study evaluated the potential of Baccharis trimera essential oil (EO) and its components in cancer therapy through the application of cytotoxicity and cell death assays. Using gas chromatography analysis, the major components of the aerial parts of the essential oil were identified as (E)-caryophyllene (18.9%), bicyclogermacrene (15.6%), and germacrene D (10.5%). Baccharis trimera essential oil (5.8 μg/mL) and α-humulene (7.8 μg/mL) presented strong cytotoxic activity, while (E)-caryophyllene (11.5 μg/mL) and caryophyllene oxide (> 100.0 μg/mL) showed moderate and low activities, respectively, against MCF-7 cell lines. Against HepG2 cell lines, B. trimera essential oil (10.4 μg/mL), α-humulene (17.1 μg/mL), and caryophyllene oxide (19.4 μg/mL) exhibited moderate activity, while (E)-caryophyllene (52.3 μg/mL) displayed low activity against HepG2 cell lines. The selectivity index values of EO (MCF-7 and HepG2), α-humulene and (E)-caryophyllene (MCF-7), and caryophyllene oxide (HepG2) were found between 1.1 and 2.8, compared with MCF-10A cells. The annexin-V and Hoechst / propidium iodide assays performed with essential oil, (E)-caryophyllene, α-humulene, and caryophyllene oxide showed apoptosis and necrosis mechanisms for all cell lines. Based on these findings, B. trimera essential oil and its components can be considered as potential therapeutic agents against cancer.","PeriodicalId":19680,"journal":{"name":"Orbital: The Electronic Journal of Chemistry","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2023-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45218372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Spectral Voltage Contour Plots of Optical Constants and Interface Parameters of the Active Layer of a Multilayer Structure Suspended Particle Device Smart Window from Clear on to Dark off States 多层结构悬浮粒子器件智能窗口从亮态到暗态的光学常数和活性层界面参数的光谱电压等值线图

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Orbital: The Electronic Journal of Chemistry Pub Date : 2023-04-05 DOI: 10.17807/orbital.v15i1.16470

D. Barrios, C. Alvarez

引用次数: 0

Fluorescence Spectroscopy and Silica Gel Applied as a Tool for Capture and Detection of Compressor Lubricant Oils 荧光光谱和硅胶在压缩机润滑油捕获和检测中的应用

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Orbital: The Electronic Journal of Chemistry Pub Date : 2023-04-05 DOI: 10.17807/orbital.v15i1.16398

Claudio Yamamoto Morassuti, S. Lima, L. H. da Cunha Andrade

{"title":"Fluorescence Spectroscopy and Silica Gel Applied as a Tool for Capture and Detection of Compressor Lubricant Oils","authors":"Claudio Yamamoto Morassuti, S. Lima, L. H. da Cunha Andrade","doi":"10.17807/orbital.v15i1.16398","DOIUrl":"https://doi.org/10.17807/orbital.v15i1.16398","url":null,"abstract":"Here, we report the use of fluorescence spectroscopy for the identification of lubricant oils used in reciprocating compressors, and the use of silica gel as an adsorbent to capture lubricant oil vapors. The silica gel was tested for adsorption of lubricant oil vapors, by heating the samples at 200°C, the emission spectrum of the lubricant oils is observed on the silica gel layer, over 20 min of heating. The spectrum of the lubricant oils over the silica gel layer presents a redshift, an indication of the degradation effect. In order to investigate this effect on the optical properties, we conducted an experiment by heating the samples at (130 ± 4) °C, and collected at different times. The MID-infrared absorption of the samples presents bands of oxygen-containing groups at 1010 and 1050 cm-1, and NIR infrared absorption measurements at 3444 cm-1 show an increase in the hydroperoxide band during the degradation time. These two results indicate that the oxidation process is associated with the observed redshift of the absorption and emission bands in lubricant oils and over the adsorbent layer.","PeriodicalId":19680,"journal":{"name":"Orbital: The Electronic Journal of Chemistry","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2023-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47836333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Assessment of High School Students’ Ability to Solve Structured Problems with Ideal Model on Acid-Base 用酸碱理想模型评价高中生解决结构化问题的能力

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Orbital: The Electronic Journal of Chemistry Pub Date : 2023-01-03 DOI: 10.17807/orbital.v14i4.16294

Deni Ainur Rokhim, A. Atikah, Isma Yanti Vitarisma, S. Rahayu, M. Muntholib

{"title":"Assessment of High School Students’ Ability to Solve Structured Problems with Ideal Model on Acid-Base","authors":"Deni Ainur Rokhim, A. Atikah, Isma Yanti Vitarisma, S. Rahayu, M. Muntholib","doi":"10.17807/orbital.v14i4.16294","DOIUrl":"https://doi.org/10.17807/orbital.v14i4.16294","url":null,"abstract":"Problem-solving is one of the abilities that a student must-have in the 21st century. This is because students' ability to solve problems is expected to increase their competence of higher-order thinking skills (HOTS). Problem-solving ability can be improved in several ways for example, the use of a certain instructional model, worksheets, and assessment or assessment based on problem-solving. This study aimed to develop and implement structured problem-solving assessment with the IDEAL model on acid-base materials, salt hydrolysis, buffer solutions, and acid-base titrations to examine students' problem-solving abilities. The instrument development model used adapts the ADDIE model with four steps, namely analysis, planning, development, and implementation. The research sample were 34 high school students in grade 11 in Sidoarjo, East Java. The result is that the problem-solving ability with the lowest percentage are in the acid-base titration material for the Act on strategy indicator at 27.21%, while the highest percentage of skills are found in the buffer solution material for the Explore solution indicator at 89.5%. This study implies that the test instrument for further research is to measure students' ability to solve structured problems with the IDEAL model on acid and base. This study implies that the test instrument for further research measures students' ability to solve structured problems with the IDEAL model on acid-base, salt hydrolysis, buffer solution, and acid titration. So that the problem solving process with the integration of problem solving problems can improve students' critical thinking.","PeriodicalId":19680,"journal":{"name":"Orbital: The Electronic Journal of Chemistry","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2023-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43931650","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Recent Studies of Corrosion - Fatigue Crack Growth on the 7081-T73511 Aluminium Alloy 7081-T73511铝合金腐蚀疲劳裂纹扩展研究进展

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Orbital: The Electronic Journal of Chemistry Pub Date : 2023-01-03 DOI: 10.17807/orbital.v14i4.17209

J. Moreto, W. B. Bose Filho

引用次数: 0