Paediatric Respiratory Reviews最新文献_第9页

Airway epithelial development and function: A key player in asthma pathogenesis? 气道上皮的发育和功能：哮喘发病机制的关键因素？

IF 5.8 3区医学

Paediatric Respiratory Reviews Pub Date : 2023-09-01 DOI: 10.1016/j.prrv.2023.04.005

Grigorios Chatziparasidis , Andrew Bush , Maria Rafailia Chatziparasidi , Ahmad Kantar

引用次数: 0

Variable and evolving degrees of CFTR dysfunction: Implications for diagnosis and clinical management CFTR功能障碍的变化和发展程度：对诊断和临床管理的意义。

IF 5.8 3区医学

Paediatric Respiratory Reviews Pub Date : 2023-09-01 DOI: 10.1016/j.prrv.2023.07.001

A. Shawcross, J.C. Davies, R. Pabary

引用次数: 0

Airway clearance in patients with neuromuscular disease 神经肌肉疾病患者的气道清除率。

IF 5.8 3区医学

Paediatric Respiratory Reviews Pub Date : 2023-09-01 DOI: 10.1016/j.prrv.2023.02.002

Alexander Ilan Gipsman , Nicole Christine Lapinel , Oscar Henry Mayer

{"title":"Airway clearance in patients with neuromuscular disease","authors":"Alexander Ilan Gipsman , Nicole Christine Lapinel , Oscar Henry Mayer","doi":"10.1016/j.prrv.2023.02.002","DOIUrl":"10.1016/j.prrv.2023.02.002","url":null,"abstract":"<div><p><span>Airway clearance is a critical component of both maintenance of respiratory health and management of acute respiratory illnesses. The process of effective airway clearance begins with the recognition of secretions in the airway and culminates in expectoration or swallowing. There are multiple points on this continuum at which </span>neuromuscular disease<span><span><span><span> causes impaired airway clearance. This can result in an otherwise mild upper respiratory illness progressing unabated from an easily managed condition to a severe, life-threatening lower respiratory illness requiring intensive therapy for patient recovery. Even during periods of relative health, airway protective mechanisms can be compromised, and patients may have difficulty managing average quantities of secretions. This review summarizes airway clearance physiology and pathophysiology<span>, mechanical and pharmacologic treatment modalities, and provides a practical approach for managing secretions </span></span>in patients with neuromuscular disease. Neuromuscular disease is an umbrella term used to describe disorders that involve dysfunction of </span>peripheral nerves<span>, the neuromuscular junction, or </span></span>skeletal muscle<span><span>. Although this paper specifically reviews airway clearance pertaining to those with neuromuscular diseases (e.g., muscular dystrophy<span>, spinal muscular atrophy, myasthenia gravis), most of its content is relevant to the management of patients with </span></span>central nervous system disorders<span> such as chronic static encephalopathy caused by trauma, metabolic or genetic abnormalities, congenital infection, or neonatal hypoxic-ischemic injury.</span></span></span></p></div>","PeriodicalId":19658,"journal":{"name":"Paediatric Respiratory Reviews","volume":"47 ","pages":"Pages 33-40"},"PeriodicalIF":5.8,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9076576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Cystic Fibrosis screen positive, inconclusive diagnosis (CFSPID) to Cystic Fibrosis: Detecting disease with serial assessments 囊性纤维化筛查阳性，非结论性诊断（CFSPID）囊性纤维化：用系列评估检测疾病。

IF 5.8 3区医学

Paediatric Respiratory Reviews Pub Date : 2023-09-01 DOI: 10.1016/j.prrv.2023.06.002

J. Manzoor, D.A. Hughes

引用次数: 0

The United States’ decision to mask children as young as two for COVID-19 has been extended into 2023 and beyond: The implications of this policy 美国为新冠肺炎两岁儿童戴口罩的决定已延长至2023年及以后：这项政策的影响。

IF 5.8 3区医学

Paediatric Respiratory Reviews Pub Date : 2023-09-01 DOI: 10.1016/j.prrv.2023.04.004

Tracy Beth Høeg , Sebastián González-Dambrauskas , Vinay Prasad

引用次数: 3

Cystic fibrosis to CFSPID: Burden of care vs need and rational approach to weaning therapies CFSPID的囊性纤维化：护理负担与需求以及断奶治疗的合理方法。

IF 5.8 3区医学

Paediatric Respiratory Reviews Pub Date : 2023-09-01 DOI: 10.1016/j.prrv.2023.07.002

S. Hadjisymeou Andreou, J.C. Davies

引用次数: 0

Long-term non-invasive ventilation in children: Transition from hospital to home 儿童长期无创通气：从医院到家庭的过渡。

IF 5.8 3区医学

Paediatric Respiratory Reviews Pub Date : 2023-09-01 DOI: 10.1016/j.prrv.2023.01.002

Joanna E. MacLean , Brigitte Fauroux

引用次数: 5

The infant with bronchopulmonary dysplasia on home oxygen: The oxygen weaning conundrum in the absence of good evidence 在家吸氧的支气管肺发育不良婴儿：在缺乏充分证据的情况下的氧气断奶难题。

IF 5.8 3区医学

Paediatric Respiratory Reviews Pub Date : 2023-09-01 DOI: 10.1016/j.prrv.2023.01.003

Dominic A. Fitzgerald

{"title":"The infant with bronchopulmonary dysplasia on home oxygen: The oxygen weaning conundrum in the absence of good evidence","authors":"Dominic A. Fitzgerald","doi":"10.1016/j.prrv.2023.01.003","DOIUrl":"10.1016/j.prrv.2023.01.003","url":null,"abstract":"<div><h3>Summary</h3><p><span>Bronchopulmonary dysplasia<span> [BPD] is the most common complication of extremely preterm delivery and its optimal management remains challenging because of a lack of evidence to guide management. There has been improvement in the management of evolving BPD in the </span></span>neonatal intensive care unit<span> (NICU). The threshold for provision of home oxygen therapy, often occurring because of a preference for earlier discharge from the NICU, creates tensions for clincians and families. Once discharged in supplemental oxygen, the approaches for the weaning of this therapy vary considerably across the world. Regardless of guidelines and multidisciplinary team support, up to a third of families of an infant with BPD elect to withdraw home oxygen therapy independently of medical advice. There is a pressing need to derive evidence to better inform practice, generate international consensus and undertake large, appropriately funded, longitudinal studies of BPD with clinically meaningful outcomes (respiratory, cardiovascular and neurodevelopmental) from infancy to adulthood.</span></p></div>","PeriodicalId":19658,"journal":{"name":"Paediatric Respiratory Reviews","volume":"47 ","pages":"Pages 11-15"},"PeriodicalIF":5.8,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10774737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Patient rotation chest X-rays and the consequences of misinterpretation in paediatric radiology 患者旋转胸部X光片和儿科放射学中误解的后果。

IF 5.8 3区医学

Paediatric Respiratory Reviews Pub Date : 2023-09-01 DOI: 10.1016/j.prrv.2023.05.003

Jani Marais , Shyam Sunder B. Venkatakrishna , Juan S. Calle-Toro , Pierre Goussard , Ernst Eber , Savvas Andronikou

{"title":"Patient rotation chest X-rays and the consequences of misinterpretation in paediatric radiology","authors":"Jani Marais , Shyam Sunder B. Venkatakrishna , Juan S. Calle-Toro , Pierre Goussard , Ernst Eber , Savvas Andronikou","doi":"10.1016/j.prrv.2023.05.003","DOIUrl":"10.1016/j.prrv.2023.05.003","url":null,"abstract":"<div><h3>Purpose</h3><p>We aimed to demonstrate the consequences of rotation on neonatal chest radiographs and how it affects diagnosis. In addition, we demonstrate methods for determining the presence and direction of rotation.</p></div><div><h3>Background</h3><p>Patient rotation is common in chest X-rays of neonates. Rotation is present in over half of chest X-rays from the ICU, contributed to by unwillingness of technologists to reposition new-borns for fear of dislodging lines and tubes.</p><p>There are six main effects of rotation on supine paediatric chest X-rays: 1) unilateral hyperlucency of the side that the patient is rotated towards; 2) the side ‘up’ appears larger; 3) apparent deviation of the cardiomediastinal shadow in the direction that the chest is rotated towards; 4) apparent cardiomegaly; 5) distorted cardio-mediastinal configuration; and 6) reversed position of the tips of the umbilical artery and vein catheters with rotation to the left. These effects can cause diagnostic errors due to misinterpretation, including air-trapping, atelectasis, cardiomegaly, and pleural effusions, or disease may be masked. We demonstrate the methods of evaluating rotation with examples, including a 3D model of the bony thorax as a guide. In addition, multiple examples of the effects of rotation are provided including examples where disease was misinterpreted, underestimated or masked.</p></div><div><h3>Conclusion</h3><p>Rotation is often unavoidable in neonatal chest X-rays, especially in the ICU. It is therefore important for physicians to recognise rotation and its effects, and to be aware that it can mimic or mask disease.</p></div>","PeriodicalId":19658,"journal":{"name":"Paediatric Respiratory Reviews","volume":"47 ","pages":"Pages 41-50"},"PeriodicalIF":5.8,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9580293","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bronchiolitis therapies and misadventures 细支气管炎的治疗和不幸

IF 5.8 3区医学

Paediatric Respiratory Reviews Pub Date : 2023-06-01 DOI: 10.1016/j.prrv.2022.09.003

Rosalie S.N. Linssen , Michael S. Schechter , Bruce K. Rubin

引用次数: 2