Paediatric Respiratory Reviews最新文献_第4页

Pulmonary hemorrhage in preterm infants born <29 weeks’ gestation: a population cohort study 妊娠<29周的早产儿肺出血：一项人群队列研究

IF 4 3区医学

Paediatric Respiratory Reviews Pub Date : 2026-03-01 Epub Date: 2025-04-09 DOI: 10.1016/j.prrv.2025.04.001

Pranav R Jani , Traci-Anne Goyen , James Elhindi , Rajesh Maheshwari , Daphne D’Cruz , Himanshu Popat , Mohamed Abdel-Latif , Melissa Luig , Dharmesh Shah

{"title":"Pulmonary hemorrhage in preterm infants born <29 weeks’ gestation: a population cohort study","authors":"Pranav R Jani , Traci-Anne Goyen , James Elhindi , Rajesh Maheshwari , Daphne D’Cruz , Himanshu Popat , Mohamed Abdel-Latif , Melissa Luig , Dharmesh Shah","doi":"10.1016/j.prrv.2025.04.001","DOIUrl":"10.1016/j.prrv.2025.04.001","url":null,"abstract":"<div><h3>Objective</h3><div>To evaluate the incidence, clinical characteristics and outcomes of pulmonary hemorrhage (PH) in preterm infants who were born <29 weeks’ gestation in relation to their small for gestational age (SGA) status.</div></div><div><h3>Study Design</h3><div>This retrospective cohort study included preterm infants born <29 weeks’ gestation and admitted to one of eight tertiary perinatal hospitals in New South Wales and The Australian Capital Territory, Australia from 1 January 2007 to 31 December 2019. Data for analysis was obtained from the Neonatal Intensive Care Units’ (NICUs) database. Temporal trends and changes in the outcomes were examined using multivariable logistic regression models.</div></div><div><h3>Results</h3><div>The median gestational age was 27 weeks’ (interquartile range (IR): 25–28) and the median birth weight was 928 g (IR: 756–1,106). PH occurred in 281/4,823 infants (5.8 %). PH more than doubled in SGA compared to appropriately grown infants (11.1 %: 39/353 versus 5.4 %: 242/4,470, difference 5.7; 95 % CI:2.14–9.12) and in infants born <26 weeks compared to ≥26 weeks (137/1,356: 10.1 % versus 144/3,467: 4.2 %, difference 5.9; 95 % CI:4.16–7.63). After confounder adjustments, PH was associated with a higher predischarge mortality (OR:3.97, 95 % CI:3.00–5.24) and severe intraventricular hemorrhage (OR:4.2, 95 % CI:3.10–5.67) but made no difference in levels of functional impairment at 2–3 years corrected age (OR:1.13, 95 % CI:0.77–1.66).</div></div><div><h3>Conclusion</h3><div>PH was more common in infants born SGA and in those born <26 weeks’ gestation. PH was associated with poorer predischarge clinical outcomes. Timely risk prediction is needed to improve outcomes in these infants.</div></div>","PeriodicalId":19658,"journal":{"name":"Paediatric Respiratory Reviews","volume":"57 ","pages":"Pages 57-64"},"PeriodicalIF":4.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144026655","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Socioeconomic determinants of outcomes in childhood asthma 儿童哮喘结局的社会经济决定因素。

IF 4 3区医学

Paediatric Respiratory Reviews Pub Date : 2026-03-01 Epub Date: 2025-03-08 DOI: 10.1016/j.prrv.2025.03.001

Karl A. Holden , Daniel B. Hawcutt , Ian P. Sinha

引用次数: 0

Pediatric pulmonary and sleep medicine – Best recent articles to read in 2025 儿科肺部和睡眠医学- 2025年最值得阅读的最新文章。

IF 4 3区医学

Paediatric Respiratory Reviews Pub Date : 2026-03-01 Epub Date: 2025-04-05 DOI: 10.1016/j.prrv.2025.04.002

Bruce K. Rubin

引用次数: 0

Severe asthma in adolescents: Clinical implications and beyond 青少年严重哮喘：临床意义及其他。

IF 4 3区医学

Paediatric Respiratory Reviews Pub Date : 2026-03-01 Epub Date: 2025-02-04 DOI: 10.1016/j.prrv.2025.01.006

Francesca Bonomo , Giuliana Ferrante , Michele Piazza , Laura Tenero , Marco Zaffanello , Giorgio Piacentini

{"title":"Severe asthma in adolescents: Clinical implications and beyond","authors":"Francesca Bonomo , Giuliana Ferrante , Michele Piazza , Laura Tenero , Marco Zaffanello , Giorgio Piacentini","doi":"10.1016/j.prrv.2025.01.006","DOIUrl":"10.1016/j.prrv.2025.01.006","url":null,"abstract":"<div><div>Severe asthma<span> affects about 6.7% of adolescents worldwide, posing a substantial burden on their physical and psychosocial well-being. The impact of severe asthma on adolescents is multifaceted, with several factors that contribute to this burden, such as comorbidities including obesity, dysfunctional breathing, sleep-disordered breathing and mental health issues. Moreover, daily therapy management is often complex and may require lifestyle modification that could lead to a failure in treatment adherence and to peer-related stressors such as feelings of exclusion. Furthermore, adolescents with severe asthma are prone to risk-taking behaviours, including vaping and substance misuse. While current management strategies often fail to account for their developmental stage, digital technologies offer novel solutions to improve disease management. This narrative review aims to provide a comprehensive overview of the multifaceted impact of severe asthma on adolescents, addressing the main clinical management issues and exploring the role of innovative digital tools to enhance asthma management in this critical population.</span></div></div>","PeriodicalId":19658,"journal":{"name":"Paediatric Respiratory Reviews","volume":"57 ","pages":"Pages 11-16"},"PeriodicalIF":4.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143449718","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Editorial: Difficult to treat asthma in vulnerable populations 社论：易感人群的哮喘难以治疗。

IF 4 3区医学

Paediatric Respiratory Reviews Pub Date : 2026-03-01 Epub Date: 2025-11-17 DOI: 10.1016/j.prrv.2025.11.005

Emily R. Le Fevre , Dominic A. Fitzgerald

引用次数: 0

Chalazion and hordeolum in paediatric patients with cystic fibrosis on elexacaftor/tezacaftor/ivacaftor 儿童囊性纤维化患者使用elexaftor /tezacaftor/ivacaftor后的反应和反应。

IF 4 3区医学

Paediatric Respiratory Reviews Pub Date : 2026-03-01 Epub Date: 2025-11-17 DOI: 10.1016/j.prrv.2025.11.002

Nathan Lieu , Jagdev Singh , Melinda Solomon , Sharon Hunt , Sharon Simonds , Christie Boyton , Chetan Pandit , Dominic A. Fitzgerald , Hiran Selvadurai

引用次数: 0

Severe childhood asthma in low and middle-income countries 低收入和中等收入国家的严重儿童哮喘。

IF 4 3区医学

Paediatric Respiratory Reviews Pub Date : 2026-03-01 Epub Date: 2025-06-12 DOI: 10.1016/j.prrv.2025.06.002

Jose A. Castro-Rodriguez , Manuel E. Soto-Martínez , Carlos E. Rodriguez-Martinez , Helena Teresinha Mocelin , Gilberto Bueno Fischer , Javier Mallol

{"title":"Severe childhood asthma in low and middle-income countries","authors":"Jose A. Castro-Rodriguez , Manuel E. Soto-Martínez , Carlos E. Rodriguez-Martinez , Helena Teresinha Mocelin , Gilberto Bueno Fischer , Javier Mallol","doi":"10.1016/j.prrv.2025.06.002","DOIUrl":"10.1016/j.prrv.2025.06.002","url":null,"abstract":"<div><div>Although severe asthma in low- and middle-income countries (LMICs) is relatively uncommon in children and adolescents (2.1 % and 4.3 %, respectively), it results in significant morbidity, occasional fatality, and great challenges of management, compared to high-income countries. Additionally, nearly 6 % of infants in LMICs experience nighttime symptoms on a weekly basis. Socioeconomic inequities and exposure to environmental risk factors contributed to variability in prevalence, with children from disadvantaged backgrounds being at a higher risk of developing the condition. Numerous preventable risk factors have been identified in these regions, including tobacco smoke, indoor and outdoor pollution (e.g., the use of biomass fuels), allergens, diet, and urbanization, among other lifestyle factors. Almost half of the patients with severe asthma received inadequate treatment. For example, only 55 % use inhaled corticosteroids (ICS), and while most physicians prefer pressurized metered-dose inhalers, only a third recommend using spacers. In some countries, oral short-acting beta agonists and theophylline are still used as treatment options. Compared to fixed-dose ICS/long-acting beta-agonists (LABA), maintenance and reliever therapy (MART), adding tiotropium, and triple therapy (ICS + LABA + LAMA) are cost-effective options in LMICs. Biologic drugs are expensive and have limited access, and studies have shown that omalizumab and dupilumab are not cost-effective treatments in LMICs. Barriers to adequate follow-up include poorly organized health services, limited spirometry, and patients’ non-compliance. Public health efforts should prioritize improving access to affordable asthma medications, enhancing diagnostic capacity in underserved areas, and addressing environmental risk factors that contribute to asthma.</div></div>","PeriodicalId":19658,"journal":{"name":"Paediatric Respiratory Reviews","volume":"57 ","pages":"Pages 17-26"},"PeriodicalIF":4.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144743483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

What a paediatric pulmonologist needs to know about vaping 关于电子烟，儿科肺科医生需要知道的事情。

IF 4 3区医学

Paediatric Respiratory Reviews Pub Date : 2026-03-01 Epub Date: 2025-04-16 DOI: 10.1016/j.prrv.2025.04.006

M. Horgan , D.W. Cox

{"title":"What a paediatric pulmonologist needs to know about vaping","authors":"M. Horgan , D.W. Cox","doi":"10.1016/j.prrv.2025.04.006","DOIUrl":"10.1016/j.prrv.2025.04.006","url":null,"abstract":"<div><div>Electronic nicotine delivery systems (ENDS), often known as e-cigarettes or vapes, have transitioned from a smoking cessation tool to a widely used recreational product, particularly among adolescents. The prevalence of youth vaping has surged, driven by accessibility, appealing flavours, targeted marketing, and the rise of disposable vapes. Despite regulations and legislation, underage access remains widespread. Adolescents often perceive vaping as less harmful than smoking, though emerging evidence links e-cigarette use to pulmonary toxicity, increased respiratory symptoms, and potential long-term lung damage. Studies indicate associations between vaping and asthma, bronchiolitis, and chronic obstructive pulmonary disease. Additionally, harmful chemical by-products produced from e-liquid decomposition, raise future health concerns. Regulatory measures vary globally, and the effectiveness of different strategies remains unclear. Paediatric pulmonologists play a key role in addressing this epidemic through patient education and advocacy. Urgent research is needed to assess the long-term health impacts of vaping and develop the most effective vaping cessation interventions.</div></div>","PeriodicalId":19658,"journal":{"name":"Paediatric Respiratory Reviews","volume":"57 ","pages":"Pages 69-74"},"PeriodicalIF":4.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144026715","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Towards standardized and clinically relevant definitions of hypoxemia and hyperoxemia in preterm infants: A systematic review 早产儿低氧血症和高氧血症的标准化和临床相关定义：一项系统综述。

IF 4 3区医学

Paediatric Respiratory Reviews Pub Date : 2026-03-01 Epub Date: 2025-03-11 DOI: 10.1016/j.prrv.2025.03.002

N.H. Gangaram-Panday , J.A. Poppe , A.N. Tintu , C.F. Poets , I.K.M. Reiss , W. van Weteringen , S.H.P. Simons

引用次数: 0

What was that you said? 你刚才说什么？

IF 4 3区医学

Paediatric Respiratory Reviews Pub Date : 2026-02-18 DOI: 10.1016/j.prrv.2026.02.003

Bruce K Rubin, Dominic A Fitzgerald

引用次数: 0