One Health最新文献

{"title":"Evolution of foodborne disease surveillance in China: A 32-year journey from monitoring to early warning","authors":"Zhifang Zhang ,&nbsp;Weiwei Chen ,&nbsp;Xuejie Liu ,&nbsp;Yanqin Deng ,&nbsp;Huarong Hong ,&nbsp;Shenggen Wu","doi":"10.1016/j.onehlt.2026.101348","DOIUrl":"10.1016/j.onehlt.2026.101348","url":null,"abstract":"<div><div>China's foodborne disease (FBD) surveillance system was implemented later than those in most developed countries. However, in the past 32 years, it has undergone improvements: from pilot projects to full coverage; from a passive mode to an active one; from localized development to the integration of international standards; and from a single function to a comprehensive system.</div><div>During this process, China's health administrative departments have adjusted their regulatory departments and functions for FBDs in response to evolving epidemiological patterns of FBD. Simultaneously, they have used a phased, step-by-step approach to promote the use of whole genome sequencing (WGS) technology, according to the level of regional economic development, to facilitate FBD traceability. However, the system must be further improved in terms of traceability capabilities, multi-departmental collaboration, and data sharing mechanisms. At various historical stages, FBD outbreaks in China have shown distinct regional characteristics, and the spectrum of common pathogenic bacteria in China differs from those in the Europe Union (EU) and the United States. In China, diseases caused by microorganisms such as <em>Vibrio parahaemolyticus, Salmonella, Staphylococcus aureus, Bacillus cereus,</em> and <em>Echerichia coli</em> are dominant. Since 2011, the number of FBD outbreaks has increased each year, and has been accompanied by a decline in the case fatality rate, thus reflecting improvements in foodborne detection technology in China. In the future, further integration of advanced technologies such as WGS will be necessary to enhance surveillance sensitivity, strengthen active and targeted surveillance of key populations, and establish a risk warning model tailored to China's dietary characteristics, thereby increasing the effectiveness of FBD prevention and control.</div></div>","PeriodicalId":19577,"journal":{"name":"One Health","volume":"22 ","pages":"Article 101348"},"PeriodicalIF":4.5,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146188349","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Herpes B virus and the neglected risk of zoonotic spillover.","authors":"Yujin Kim, Ji Min Lee, Jung Joo Hong","doi":"10.1016/j.onehlt.2026.101459","DOIUrl":"10.1016/j.onehlt.2026.101459","url":null,"abstract":"<p><strong>Objectives: </strong>To evaluate the zoonotic risk of <i>Simplexvirus macacine alpha 1</i> (B virus), a macaque-associated alphaherpesvirus that can cause severe and frequently fatal encephalitis in humans, and to assess the potential for cross-border risk through international macaque trade.</p><p><strong>Methods: </strong>A comprehensive literature review was conducted to identify documented human B virus infections between 1932 and 2024. International trade records for <i>Macaca</i> species from the CITES Trade Database (2019-2022) were analyzed for trade volume, source, and purpose. Quarantine regulations across countries were compared, using South Korea as a case study.</p><p><strong>Results: </strong>Among 33 documented infections, most were occupational exposures in laboratory settings. Recent cases highlight non-occupational risks, including viral reactivation decades after exposure. From 2019 to 2022, exporter-reported CITES data documented over 170,000 live macaques in international trade, with an increasing proportional share of wild-caught animals. Regulatory frameworks varied by country, with South Korea relying on recommendation-based biosafety oversight, whereas the U.S. applies legally binding import-control measures.</p><p><strong>Conclusions: </strong>Although rare, B virus poses a severe and underappreciated zoonotic threat. The increasing wild-caught macaque trade and gaps in quarantine protocols necessitate stronger international coordination and the implementation of standardized biosafety regulations within a One Health framework.</p>","PeriodicalId":19577,"journal":{"name":"One Health","volume":"22 ","pages":"101459"},"PeriodicalIF":5.3,"publicationDate":"2026-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13265646/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148265625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Free-ranging hedgehogs as sentinels of environmental extended-spectrum β-lactamase-producing Enterobacterales.","authors":"Tal Zilberman Daniels, David Eshar, Yael Aharon, Sharon Amit","doi":"10.1016/j.onehlt.2026.101458","DOIUrl":"10.1016/j.onehlt.2026.101458","url":null,"abstract":"<p><p>Antimicrobial resistance (AMR), particularly among extended-spectrum β-lactamase-producing Enterobacterales (ESBL-PE), represents a major challenge at the human-animal-environment interface. We conducted a nationwide study assessing faecal carriage of ESBL-PE in free-ranging hedgehogs, a synanthropic species well adapted to urban environments. Between December 2022 and September 2023, 246 hedgehogs rescued across Israel and admitted to the country's sole wildlife hospital were screened on admission, with all isolates undergoing antimicrobial susceptibility testing. Overall, 71% of hedgehogs carried at least one ESBL-PE isolate, and 2% harboured carbapenem-resistant Enterobacterales. <i>Escherichia coli</i> was the predominant species, followed by <i>Citrobacter</i>, <i>Klebsiella</i>, and <i>Enterobacter</i> spp. High resistance rates were observed to quinolones (83%) and trimethoprim-sulfamethoxazole (46%). Carriage prevalence varied over time, with higher rates observed during months associated with holiday periods and increased outdoor recreational activity. These findings suggest that free-ranging hedgehogs may serve as a complementary sentinel species for monitoring AMR patterns in One Health contexts.</p>","PeriodicalId":19577,"journal":{"name":"One Health","volume":"22 ","pages":"101458"},"PeriodicalIF":5.3,"publicationDate":"2026-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13253185/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148252557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Optimizing wild bird fecal surveillance sites for HPAI through risk estimation using machine learning algorithms.","authors":"SunMin Kim, Hyunjun Cho, Hyesung Jeong, Dae Sung Yoo, Kyuyoung Lee, Hu Suk Lee, Kyung-Duk Min","doi":"10.1016/j.onehlt.2026.101457","DOIUrl":"10.1016/j.onehlt.2026.101457","url":null,"abstract":"<p><strong>Background: </strong>Wild birds are major reservoirs contributing to the spread of highly pathogenic avian influenza (HPAI). Accordingly, fecal-based surveillance of wild birds has been implemented as an early warning system for poultry in South Korea. However, the efficiency of the current system remains limited due to the absence of a quantitative basis. This study aimed to develop a risk-based strategy for optimizing fecal sampling sites, thereby strengthening early warning capacity and preventing the introduction of HPAI into poultry farms.</p><p><strong>Methods: </strong>The study area comprised 110 designated surveillance areas divided into 1-km edge hexagonal grids. The study period covered October to February from 2021 to 2024. For each grid, we integrated wild bird fecal sampling data with various categories of factors. The dependent variable was the detection of avian influenza virus (AIV) in wild bird feces, while all other variables served as predictors. The risk of AIV detection was estimated using machine learning algorithms, including logistic regression, gradient boosting machine, extreme gradient boosting, and an ensemble model. Model performance was evaluated using the area under the curve (AUC), sensitivity, specificity, and accuracy.</p><p><strong>Results: </strong>The ensemble model achieved the best predictive performance. Climatic factors, sample size, population, and elevation were identified as the most influential predictors. Spatial inconsistency was observed between the current sampling sites and the proposed risk-based sampling sites.</p><p><strong>Conclusions: </strong>The proposed risk-based framework enables prioritization of sampling sites, thereby optimizing fecal-based surveillance for HPAI. This approach is expected to enhance the efficiency of EWS and contribute to the prevention of HPAI spread to poultry.</p>","PeriodicalId":19577,"journal":{"name":"One Health","volume":"22 ","pages":"101457"},"PeriodicalIF":5.3,"publicationDate":"2026-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13253128/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148252543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"High-resolution climate modelling of fasciolosis risk in Australia: A One Health early-warning framework.","authors":"Rana M Athar Ali, Mark A Stevenson, Leah Tyrell, Nichola E D Calvani, Travis Beddoe, Grant Rawlin, Terry Spithill, Neil D Young, Abdul Jabbar","doi":"10.1016/j.onehlt.2026.101451","DOIUrl":"10.1016/j.onehlt.2026.101451","url":null,"abstract":"<p><p>Fasciolosis, caused by the liver fluke <i>Fasciola hepatica</i>, is a climate-sensitive parasitic disease that threatens livestock health, productivity and farm profitability, with broader implications for food security, rural livelihoods, and sustainable food systems. The disease is endemic in Victoria, Australia, where environmental and climatic conditions favour parasite transmission at the livestock-environment interface. This study used high-resolution (5 km²) climate data from 40,504 grid points across Victoria to validate a Growing Degree Days (GDD) model for estimating fasciolosis risk over the past 50 years (1975-2024) and to project future risk for 2050 and 2090 under medium (RCP 4.5) and high (RCP 8.5) representative concentration pathways. Linear regression analysis identified a strong relationship between observed fasciolosis prevalence and modelled risk values (R² = 0.94, <i>p</i> < 0.003). Historical data analyses showed substantial interannual variability, with consistently higher risk in eastern Victoria, followed by the western and northern regions. Under future climate scenarios, fasciolosis risk increased spatially 2-fold in Barwon and 3-fold in the Great South Coast, particularly under the RCP 8.5 scenario in 2090. Risk remained sustained in Gippsland, especially in southern areas, covering 35% of the region, while a modest increase (5%) was projected for Greater Melbourne relative to a baseline risk of 45%. These findings highlight important One Health implications, as climate-driven changes in fasciolosis risk may undermine livestock productivity, and challenge the resilience of livestock-derived food systems. The study provides an evidence base to support climate-responsive surveillance, risk-based control strategies, and integrated animal health and environmental policy development.</p>","PeriodicalId":19577,"journal":{"name":"One Health","volume":"22 ","pages":"101451"},"PeriodicalIF":5.3,"publicationDate":"2026-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13227242/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148157340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Community knowledge, attitudes and practices related to cystic echinococcosis in Ethiopia: Implications for control.","authors":"Debela A Efa, Tao Wang, Getachew Terefe, Mark A Stevenson, Abdul Jabbar, Robin B Gasser","doi":"10.1016/j.onehlt.2026.101456","DOIUrl":"10.1016/j.onehlt.2026.101456","url":null,"abstract":"<p><p>Cystic echinococcosis (CE), caused by <i>Echinococcus granulosus</i> sensu lato, is a parasitic zoonosis of major public health and economic significance. Ethiopia is among the most affected countries, yet baseline data on community knowledge, attitudes and practices (KAP) relating to CE remain limited. A cross-sectional questionnaire survey was administered to 310 individuals across four regions and four city administrations in central, western, southern and southwestern Ethiopia between May and August 2025. Data were analysed descriptively using chi-square tests, and multiple correspondence analysis (MCA) was applied to document latent KAP profiles in relation to education level. Respondents were predominantly male, rural and engaged in farming, although veterinarians and other occupational groups were represented. Dog ownership was common, livestock were largely grazed on open pasture, and high-risk behaviours were widespread, including free-roaming dogs, backyard slaughter, feeding infected offal to dogs, and consumption of raw vegetables and unboiled water. More than half of respondents demonstrated limited knowledge, negative attitudes and risky practices, whereas only small proportions exhibited sound knowledge, positive attitudes or safe practices. Veterinarians scored highest overall, while farmers and rural residents scored lowest, and education was strongly associated with improved knowledge and safer practices. MCA revealed heterogeneous behavioural profiles and an incomplete translation of knowledge into practice. These findings highlight persistent awareness-behaviour gaps and underscore the need for coordinated, context-specific interventions, including culturally tailored education, regular dog deworming, improved abattoir services, and guidance on safe slaughter and household hygiene, aligned with the WHO 2030 roadmap for neglected tropical diseases and the Sustainable Development Goals.</p>","PeriodicalId":19577,"journal":{"name":"One Health","volume":"22 ","pages":"101456"},"PeriodicalIF":5.3,"publicationDate":"2026-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13242029/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148199765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Training for complexity: Fostering interdisciplinary thinking in One Health graduate education.","authors":"Kristen Sullivan, Meredith R Spence Beaulieu, Jade Lyons, Emily Floess, Alexandria P Nelson, Caitlin G Niven, Savanna K Smith, Chenxing Xie, Michael Reiskind","doi":"10.1016/j.onehlt.2026.101455","DOIUrl":"10.1016/j.onehlt.2026.101455","url":null,"abstract":"<p><p>Graduate training in One Health must equip students to think across disciplines and address complex health challenges through integrative approaches. While case-based and project-based learning are increasingly used to support these goals, there is limited research on how graduate students engage in interdisciplinary exchange, particularly through peer feedback. This study examined structured peer interactions in a graduate-level One Health seminar at North Carolina State University. Six doctoral students from diverse disciplines - ranging from engineering to ecology to technical communication - shared their research projects and provided written and verbal feedback on each other's work. Using qualitative and quantitative methods, we analyzed how peer engagement shaped interdisciplinary thinking. Students consistently identified connections across One Health domains and offered insights that expanded the scope, setting, or methods of their peers' work. Notably, students contributed more ideas outside of their own disciplines than within them and frequently generated new research questions for themselves in the process. Thematic analysis revealed shared interests in environmental and ecological impact, sociocultural context, epidemiological pathways, genetic research, and policy relevance. Findings highlight the value of structured peer feedback as a tool for developing core One Health competencies, particularly systems thinking and interdisciplinary communication, and for fostering collaboration. Students demonstrated readiness to engage across disciplinary boundaries and apply One Health principles in thoughtful, practice-oriented ways. This study contributes to growing efforts to design graduate education that helps students engage meaningfully with the complexity at the heart of One Health work.</p>","PeriodicalId":19577,"journal":{"name":"One Health","volume":"22 ","pages":"101455"},"PeriodicalIF":5.3,"publicationDate":"2026-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13227214/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148157279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Regional heterogeneity of spatial-temporal characteristics and meteorological-environmental driving factors of hemorrhagic fever with renal syndrome in China.","authors":"Chuanlong Cheng, Michael Tong, Yuchen Hu, Qi Gao, Hui Zuo, Yuqi Zhang, Liang Lu, Xiujun Li","doi":"10.1016/j.onehlt.2026.101454","DOIUrl":"10.1016/j.onehlt.2026.101454","url":null,"abstract":"<p><strong>Background: </strong>Hemorrhagic fever with renal syndrome (HFRS), a major rodent-borne disease in China, exhibits shifting spatial and incidence patterns due to climate change. From a One Health perspective-integrating human, animal, and environmental health-this China-wide survey aims to identify spatiotemporal characteristics of HFRS and assess regional heterogeneity associated with meteorological and environmental factors.</p><p><strong>Methods: </strong>Using HFRS case data from 2005 to 2022 in China, this study employed a distributed lag non-linear model to examine associations with meteorological factors, and used a generalized additive mixed model to examine associations with environmental factors. The spatiotemporal effects of these factors were further analyzed across different epidemic types, climate zones, and geographical regions to identify key drivers of HFRS risk.</p><p><strong>Results: </strong>A bimodal seasonal pattern was observed, with HFRS incidence peaking in autumn/winter (<i>Apodemus</i>-Type epidemic regions) and spring (<i>Rattus</i>-Type epidemic regions). The effects of monthly mean temperature and relative humidity exhibited inverted U-shaped curves, peaking at 7.5 °C and 38%, respectively, with corresponding relative risks of 1.85 (95% CI: 1.35-2.54) and 1.21 (95% CI: 1.04-1.40). HFRS risk initially rose as precipitation increased and then declined, while extreme precipitation and snow depth inhibited HFRS risk. Impervious surface and water body percentages had greater impacts in <i>Apodemus</i>-Type epidemic regions, whereas shrubland and wetland percentages had greater impacts in <i>Rattus</i>-Type epidemic regions, indicating significant regional differences.</p><p><strong>Conclusion: </strong>HFRS exhibits geographical clustering and bimodal seasonal pattern in China, driven by regional heterogeneity in host species, meteorological and environmental factors. These spatiotemporal patterns, viewed through a One Health lens, necessitate region-specific interventions to guide precision prevention and early warning nationwide.</p>","PeriodicalId":19577,"journal":{"name":"One Health","volume":"22 ","pages":"101454"},"PeriodicalIF":5.3,"publicationDate":"2026-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13223968/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148150540","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development and implementation of an animal-inclusive Community-Led Total Sanitation program for rural Mali.","authors":"Michel Dione, Ahmadou Sow, Elizabeth D Thomas, Natalie De La Cruz, Hazara Ouedraogo, Kirk Dearden, Laura H Kwong","doi":"10.1016/j.onehlt.2026.101449","DOIUrl":"10.1016/j.onehlt.2026.101449","url":null,"abstract":"<p><strong>Background: </strong>Community-Led Total Sanitation (CLTS) does not formally include animal feces management, despite its goal to prevent fecal matter from entering the environment. By integrating animal feces management into an existing community-level program to safely manage human feces, greater reductions in exposure to feces may be achieved, supporting improvements to both human and animal health.</p><p><strong>Methods: </strong>We adapted the CLTS intervention to be animal-inclusive and piloted the resulting intervention in twenty-five villages; ten villages received an integrated human and animal feces CLTS program (A-CLTS), ten villages received standard CLTS followed by animal feces intervention components (CLTS+A), and five villages received only the standard CLTS program. Open-defecation free (ODF) status was assessed at the community level, using both human feces and animal feces indicators.</p><p><strong>Results: </strong>Our animal-inclusive CLTS intervention included development and promotion of animal confinement structures (with separate locations for sick animals); training on improved composting, manure application, hygienic milking, and hygienic birthing; and education on zoonotic diseases, animal disease management (vaccination and deworming), and the risks posed to children by close contact with animals and animal feces. Of the five villages that received standard CLTS only, only one met all ODF criteria when it was evaluated 1.5 years after CLTS triggering. The other villages were evaluated using animal-inclusive indicators for ODF and evaluated 5-6 months after triggering; four of ten CLTS+A villages and six of ten A-CLTS villages met all of the animal-inclusive ODF criteria.</p><p><strong>Conclusion: </strong>An animal-inclusive version of CLTS that included triggering activities focused on increasing awareness of the risk of both uncontained animal and human feces in the environment, proposed interventions to improve human and animal health, established village sanitation committees, and included supportive follow-up visits the potential to support participating communities achieve ODF status for both human and animal feces.</p>","PeriodicalId":19577,"journal":{"name":"One Health","volume":"22 ","pages":"101449"},"PeriodicalIF":5.3,"publicationDate":"2026-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13241646/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148199778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antimicrobial resistant <i>E. coli</i> in animals, humans and the environment within household and compound settings: A scoping review.","authors":"Fanta D Gutema, Redeat Kassahun, Kelly K Baker","doi":"10.1016/j.onehlt.2026.101452","DOIUrl":"10.1016/j.onehlt.2026.101452","url":null,"abstract":"<p><strong>Objective: </strong>This scoping review summarizes evidence on the prevalence and potential risk factors of antimicrobial-resistant (AMR) <i>E. coli</i> in animals, humans, and the environment within household and compound settings.</p><p><strong>Methods: </strong>Four databases (CINAHL, PubMed, PubMed Central, and Scopus) were searched for studies published up to October 2024.</p><p><strong>Results: </strong>Most studies (60%, 24/40) reported AMR <i>E. coli</i> in studies involving animals and humans (AH), followed by those included animals, humans, and the environment (AHE) (35%, 14/40). and animals and the environment (AE) (5%, 2/40). AMR <i>E. coli</i> was commonly detected using disk diffusion methods, often combined with PCR, WGS, MIC, or PFGE for genetic relatedness analysis. The estimated overall prevalence was 63%, 36.5%, and 46% at the AH, AHE, and AE categories, respectively. No eligible studies reported AMR <i>E. coli</i> exclusively from humans and the environment. None of the AE studies assessed genetic relatedness between isolates. However, 13 AH studies identified genetically related <i>E. coli</i> strains between animals and humans, particularly extended-spectrum β lactamase and extended-spectrum cephalosporin-resistant. Shared clonal lineages and identical resistance genes were observed among cohabiting animals and humans. Similarly, three AHE category studies reported genetic overlap involving β-lactam, carbapenem, tetracycline, and aminoglycoside resistance. Close human-animal contact, shared living environments, and the presence of multiple animal species were identified as potential contributors to transmission of resistant <i>E.coli</i> between animals and humans.</p><p><strong>Conclusion: </strong>Genetically related AMR <i>E. coli</i> strains are widespread, with strong evidence of genetic relatedness between isolates originating from animals and humans within household and compound settings.</p>","PeriodicalId":19577,"journal":{"name":"One Health","volume":"22 ","pages":"101452"},"PeriodicalIF":5.3,"publicationDate":"2026-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13217473/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148138515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}