OphthalmologyPub Date : 2026-10-20DOI: 10.1016/j.ophtha.2026.09.032
Manpreet Kaur, Vaibhav Namdev, Jeewan S Titiyal
{"title":"Corneal Ring of Trauma: Iatrogenic Endothelial Damage during Laser Capsulotomy.","authors":"Manpreet Kaur, Vaibhav Namdev, Jeewan S Titiyal","doi":"10.1016/j.ophtha.2026.09.032","DOIUrl":"https://doi.org/10.1016/j.ophtha.2026.09.032","url":null,"abstract":"","PeriodicalId":19533,"journal":{"name":"Ophthalmology","volume":" ","pages":""},"PeriodicalIF":10.9,"publicationDate":"2026-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149228246","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
OphthalmologyPub Date : 2026-10-14DOI: 10.1016/j.ophtha.2026.10.009
Margarita Labkovich, Paul T Finger
{"title":"The Second and Third Decade After 103Pd Plaque Brachytherapy for Choroidal Melanoma.","authors":"Margarita Labkovich, Paul T Finger","doi":"10.1016/j.ophtha.2026.10.009","DOIUrl":"https://doi.org/10.1016/j.ophtha.2026.10.009","url":null,"abstract":"<p><strong>Purpose: </strong>To determine long-term visual and ocular outcomes in a large cohort of patients with choroidal melanoma treated using palladium-103 (103Pd) plaque brachytherapy.</p><p><strong>Design: </strong>This is a retrospective cohort study.</p><p><strong>Participants: </strong>170 patients with a minimum of 10 years of continuous follow-up at The New York Eye Cancer Center following <sup>103</sup>Pd plaque brachytherapy treatment for choroidal melanoma.</p><p><strong>Methods: </strong>The study includes collected data consisting of patient demographic characteristics, tumor features, such as size, location, and AJCC clinical T-category (cT), visual outcomes, variables related to post-treatment retinopathy management, and long-term ocular comorbidities.</p><p><strong>Main outcome measures: </strong>The primary endpoints were tumor control, ocular conservation, and visual acuity. Secondary endpoints included long-term radiation-related complications, additional ocular interventions, and associated comorbidities. Statistical analyses were performed using the Kaplan-Meier survival method, t-tests, Wilcoxon rank-sum tests, chi-square tests, and linear regression plots.</p><p><strong>Results: </strong>Among 170 patients with a minimum 10-year follow-up there was 100% local tumor control. One eye (0.6%) was enucleated due to neovascular glaucoma and patient choice. Kaplan-Meier analysis demonstrated visual acuity retention rates of 92.7% at 12 years, 87.0% at 15 years, and 63.7% at 20 years defined as vision of 20/200 or better. Radiation retinopathy was managed with anti-vascular endothelial growth factor (anti-VEGF) therapy, intravitreal corticosteroids, and laser treatment. Tumors located closer to the fovea were associated with increased foveal radiation doses and poorer visual acuity outcomes. Treatment of juxtapapillary and circumpapillary tumors was associated with the highest rates of vision loss.</p><p><strong>Conclusions: </strong>This study is the largest and longest follow-up analysis of 103Pd plaque brachytherapy for choroidal melanoma. It provides new long-term information on tumor control, ocular morbidity, and visual outcomes that are valuable for patient counseling and therapeutic decision-making.</p>","PeriodicalId":19533,"journal":{"name":"Ophthalmology","volume":" ","pages":""},"PeriodicalIF":10.9,"publicationDate":"2026-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149183365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
OphthalmologyPub Date : 2026-10-13DOI: 10.1016/j.ophtha.2026.09.012
Sarah MacKinnon, Rachael Zacks, Brenda Barry, David A Mackey, David G Hunter, Elizabeth C Engle, Mary C Whitman
{"title":"REPLY.","authors":"Sarah MacKinnon, Rachael Zacks, Brenda Barry, David A Mackey, David G Hunter, Elizabeth C Engle, Mary C Whitman","doi":"10.1016/j.ophtha.2026.09.012","DOIUrl":"10.1016/j.ophtha.2026.09.012","url":null,"abstract":"","PeriodicalId":19533,"journal":{"name":"Ophthalmology","volume":" ","pages":""},"PeriodicalIF":10.9,"publicationDate":"2026-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149183298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
OphthalmologyPub Date : 2026-10-09DOI: 10.1016/j.ophtha.2026.09.011
Vignesh Lakshmanan
{"title":"Re: MacKinnon et al.: Prevalence of Strabismus and Decreased Stereopsis in Parents of Children with Strabismus (Ophthalmology. 2026;133:1099-1107).","authors":"Vignesh Lakshmanan","doi":"10.1016/j.ophtha.2026.09.011","DOIUrl":"https://doi.org/10.1016/j.ophtha.2026.09.011","url":null,"abstract":"","PeriodicalId":19533,"journal":{"name":"Ophthalmology","volume":" ","pages":""},"PeriodicalIF":10.9,"publicationDate":"2026-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149137885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
OphthalmologyPub Date : 2026-10-09DOI: 10.1016/j.ophtha.2026.09.013
Yan Zhang, Zheng Zhang, An-Li Duan
{"title":"Re: Zhao et al.: Incidence and Associated Factors of Myopic Maculopathy Progression After Posterior Scleral Contraction in High Myopia (Ophthalmology. 2026;133:506-514).","authors":"Yan Zhang, Zheng Zhang, An-Li Duan","doi":"10.1016/j.ophtha.2026.09.013","DOIUrl":"https://doi.org/10.1016/j.ophtha.2026.09.013","url":null,"abstract":"","PeriodicalId":19533,"journal":{"name":"Ophthalmology","volume":" ","pages":""},"PeriodicalIF":10.9,"publicationDate":"2026-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149137866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}