Ophthalmology. Retina最新文献

{"title":"Marijuana Use and Failure of Initial Surgical Management of Retinal Detachment","authors":"Jeffrey A. Brown MD , Kai R. Seely MD, MHSc , William E. Smiddy MD , Nicolas A. Yannuzzi MD , Robert O’Brien PhD , Audina M. Berrocal MD , Harry W. Flynn Jr. MD , Justin H. Townsend MD","doi":"10.1016/j.oret.2025.05.011","DOIUrl":"10.1016/j.oret.2025.05.011","url":null,"abstract":"","PeriodicalId":19501,"journal":{"name":"Ophthalmology. Retina","volume":"9 10","pages":"Pages 1025-1027"},"PeriodicalIF":5.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144078906","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Limitations of Surgical Trials for the Treatment of Retinal Diseases","authors":"John T. Thompson MD","doi":"10.1016/j.oret.2025.07.002","DOIUrl":"10.1016/j.oret.2025.07.002","url":null,"abstract":"","PeriodicalId":19501,"journal":{"name":"Ophthalmology. Retina","volume":"9 10","pages":"Pages 925-927"},"PeriodicalIF":5.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144768838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence and Risk Factors of Diabetic Macular Edema in Type 1 Diabetes: A Systematic Review and Meta-Analysis.","authors":"Pedro Marques-Couto, João Afonso, Inês Coelho-Costa, João Sérgio Neves, Manuel Falcão, Rita Laiginhas","doi":"10.1016/j.oret.2025.09.008","DOIUrl":"https://doi.org/10.1016/j.oret.2025.09.008","url":null,"abstract":"<p><strong>Topic: </strong>This systematic review and meta-analysis investigates the prevalence, natural history, clinical risk factors, and distinctive characteristics of diabetic macular edema (DME) in type 1 diabetes mellitus (T1D), highlighting comparisons with type 2 diabetes mellitus (T2D).</p><p><strong>Clinical relevance: </strong>DME is the most common vision-threatening complication of diabetic retinopathy, significantly impacting quality of life. While extensively studied in T2D, data in T1D remains limited, restricting targeted prevention and management. Given the increasing longevity of individuals with T1D, understanding its specific risk profile is critical to refine screening and treatment guidelines.</p><p><strong>Methods: </strong>This systematic review and meta-analysis was registered (PROSPERO: CRD420251011398) and performed according to PRISMA guidelines. A comprehensive literature search was performed in MedLine (via PubMed), Scopus, and Web of Science databases (July 15, 2024). Eligible studies included original observational studies explicitly reporting prevalence, incidence, natural history, or risk factors of DME in T1D patients. Studies not differentiating T1D from T2D were excluded. The risk of bias was assessed using NIH criteria. Meta-analysis and meta-regression were used for data synthesis.</p><p><strong>Results: </strong>Of the 63 studies included, 27 were eligible for meta-analysis, encompassing 40 distinct study populations and a total of 20,074 patients. The pooled prevalence of DME in T1D was 11.1% (95% CI: 7.9-14.3%, I²=99.6%). Meta-regression identified disease duration and HbA1c as significant predictors: at the sample means (19.9 years of diabetes; HbA1c 8.6%), the adjusted prevalence was 14.8%. Each additional year of disease increased prevalence by 1.2 percentage points, and each 1% increase in HbA1c raised prevalence by 4.7 percentage points, on average. Additional factors such as hypertension, dyslipidemia, and nephropathy were also associated with higher DME prevalence. The certainty of the evidence was rated as very low using the GRADE approach.</p><p><strong>Conclusions: </strong>DME prevalence in T1D is substantial, with a strong dependency on disease duration and glycemic control. Nonetheless, these findings should be interpreted with caution given the very low certainty of the evidence. These findings highlight the need for personalized screening intervals and early intervention strategies. Future research should focus on refining diagnostic criteria, integrating emerging biomarkers, and evaluating the impact of novel diabetes management technologies.</p>","PeriodicalId":19501,"journal":{"name":"Ophthalmology. Retina","volume":" ","pages":""},"PeriodicalIF":5.7,"publicationDate":"2025-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145186627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Mottled Fundus Sheen in a Highly Myopic Patient with Oguchi Disease.","authors":"Jinlian Zhan, Lin Lu, Xiujuan Zhao","doi":"10.1016/j.oret.2025.08.016","DOIUrl":"https://doi.org/10.1016/j.oret.2025.08.016","url":null,"abstract":"","PeriodicalId":19501,"journal":{"name":"Ophthalmology. Retina","volume":" ","pages":""},"PeriodicalIF":5.7,"publicationDate":"2025-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145150423","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Central Anomalous Retinoschisis with mid-PEripheral Traction.","authors":"Alessandro Feo, David Sarraf","doi":"10.1016/j.oret.2025.08.017","DOIUrl":"https://doi.org/10.1016/j.oret.2025.08.017","url":null,"abstract":"","PeriodicalId":19501,"journal":{"name":"Ophthalmology. Retina","volume":" ","pages":""},"PeriodicalIF":5.7,"publicationDate":"2025-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145150361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intraretinal Fluid Resolution in Macular Hole Surgery Without Facedown Position.","authors":"Maiko Inoue, Shin Tanaka, Tatsuya Inoue, Yasuo Yanagi, Shohei Kawasaki, Kazuaki Kadonosono","doi":"10.1016/j.oret.2025.09.006","DOIUrl":"https://doi.org/10.1016/j.oret.2025.09.006","url":null,"abstract":"","PeriodicalId":19501,"journal":{"name":"Ophthalmology. Retina","volume":" ","pages":""},"PeriodicalIF":5.7,"publicationDate":"2025-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145176653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Coats-Like Response in X-Linked Retinoschisis.","authors":"Smile Singla, Kalpana Nishad, Vinod Kumar","doi":"10.1016/j.oret.2025.08.019","DOIUrl":"https://doi.org/10.1016/j.oret.2025.08.019","url":null,"abstract":"","PeriodicalId":19501,"journal":{"name":"Ophthalmology. Retina","volume":" ","pages":""},"PeriodicalIF":5.7,"publicationDate":"2025-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145086671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Two-Year Visual, Refractive, and Anatomical Outcomes of Sutureless Intrascleral One-Piece IOL Fixation: A Prospective Study.","authors":"Paola Marolo, Guglielmo Parisi, Fabio Conte, Francesca Cimorosi, Davide Tibaldi, Matteo Fallico, Mario Damiano Toro, Enrico Borrelli, Lorenzo Motta, Agostino S Vaiano, Michele Reibaldi","doi":"10.1016/j.oret.2025.09.005","DOIUrl":"https://doi.org/10.1016/j.oret.2025.09.005","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the two-year visual, refractive, and anatomical outcomes of a foldable single-piece intraocular lens (IOL) specifically designed for sutureless intrascleral fixation in eyes without adequate capsular support.</p><p><strong>Design: </strong>Prospective, observational, multicenter study.</p><p><strong>Participants: </strong>Two hundred thirty-four eyes of 232 patients undergoing secondary IOL implantation using a standardized sutureless intrascleral fixation technique.</p><p><strong>Methods: </strong>All eyes received a foldable, one-piece acrylic IOL implanted via a scleral flap technique. Best-corrected visual acuity (BCVA), spherical equivalent (SE), refractive prediction error (PE), and endothelial cell density (ECD) were assessed at baseline, 12 months, and 24 months. A subgroup analysis using anterior segment OCT evaluated IOL tilt, decentration, and surgically induced astigmatism (SIA), Multivariate regression explored biometric predictors of refractive outcomes.</p><p><strong>Main outcome measures: </strong>Changes in BCVA, refractive stability, PE, IOL tilt and decentration, ECD, and postoperative complications.</p><p><strong>Results: </strong>Mean BCVA improved from 0.74 ± 0.30 to 0.26 ± 0.24 logMAR at 24 months (p < 0.001). SE changed from 3.52 ± 5.92 D at baseline to -0.33 ± 0.85 D at 24 months (p<0.001). A PE within ±1.00 D was achieved in 77% of eyes. Mean absolute SIA remained stable (0.86 ± 0.44 D at 12 months vs 0.90 ± 0.62 D at 24 months; p = 0.911). IOL tilt and decentration showed no significant change over time. ECD was preserved (p = 0.895). Visual decline occurred in 2.56% of eyes and no cases of IOL dislocation or endophthalmitis were observed.</p><p><strong>Conclusions: </strong>Sutureless intrascleral fixation of a single-piece foldable IOL may lead to sustained visual improvement, high refractive accuracy, stable anatomical positioning, and a low rate of complications over 24 months. This technique demonstrates good tolerability and is associated with favorable visual outcomes for secondary implantation in eyes lacking capsular support.</p>","PeriodicalId":19501,"journal":{"name":"Ophthalmology. Retina","volume":" ","pages":""},"PeriodicalIF":5.7,"publicationDate":"2025-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145113772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mycobacterium chimaera Choroiditis after Cardiac Surgery.","authors":"Joanne Li, Christopher R Fortenbach, Bobeck S Modjtahedi","doi":"10.1016/j.oret.2025.08.015","DOIUrl":"https://doi.org/10.1016/j.oret.2025.08.015","url":null,"abstract":"","PeriodicalId":19501,"journal":{"name":"Ophthalmology. Retina","volume":" ","pages":""},"PeriodicalIF":5.7,"publicationDate":"2025-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145092181","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fingerprint Sign in Familial Microphthalmia Linked to Membrane Frizzled-Related Protein Mutation.","authors":"Gonzalo Roig-Ferreruela, María Magdalena Alberto-Pestano, Jaume Català-Mora","doi":"10.1016/j.oret.2025.08.012","DOIUrl":"https://doi.org/10.1016/j.oret.2025.08.012","url":null,"abstract":"","PeriodicalId":19501,"journal":{"name":"Ophthalmology. Retina","volume":" ","pages":""},"PeriodicalIF":5.7,"publicationDate":"2025-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145081353","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}