S. Schmidt, E. Toft, C. Holst-Hansen, C. Graff, J. Struijk
{"title":"Segmentation of heart sound recordings from an electronic stethoscope by a duration dependent Hidden-Markov Model","authors":"S. Schmidt, E. Toft, C. Holst-Hansen, C. Graff, J. Struijk","doi":"10.1109/CIC.2008.4749049","DOIUrl":"https://doi.org/10.1109/CIC.2008.4749049","url":null,"abstract":"Digital stethoscopes offer new opportunities for computerized analysis of heart sounds. Segmentation of hearts sounds is a fundamental step in the analyzing process. However segmentation of heart sounds recorded with handheld stethoscopes in clinical environments is often complicated by recording and background noise. A duration-dependent hidden Markov model (DHMM) is proposed for robust segmentation of heart sounds. The DHMM model was developed and tested with heart sounds recorded at bedside with a commercially available handheld stethoscope. In a population of 60 patients, the DHMM identified 739 S1 and S2 sounds out of 744 which corresponded to a 99.3% sensitivity. There were seven incorrectly classified sounds which corresponded to a 99.1% positive predictive value. Our results suggest that DHMM could be a suitable method for segmentation of clinically recorded heart sounds.","PeriodicalId":194782,"journal":{"name":"2008 Computers in Cardiology","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124556973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
E. Mancini, L. Corazza, D. C. Cannarile, M. Soverini, S. Cavalcanti, S. Cavani, A. Fiorenzi, A. Santoro
{"title":"Short term variability of oxygen saturation during hemodialysis is a warning parameter for hypotension appearance","authors":"E. Mancini, L. Corazza, D. C. Cannarile, M. Soverini, S. Cavalcanti, S. Cavani, A. Fiorenzi, A. Santoro","doi":"10.1109/CIC.2008.4749183","DOIUrl":"https://doi.org/10.1109/CIC.2008.4749183","url":null,"abstract":"Acute hypotension is a frequent complication of hemodialysis. Blood oxygenation may play a role in hypotension and hypoxemia may be considered as a surrogate marker of hemodynamic instability. Continuous, non-invasive monitoring of oxygen saturation (SO2) during hemodialysis is now possible, by means of sensors measuring SO2 in blood entering the dialyzer. The aim of the present work was to analyze the short-term variability of SO2 during hemodialysis in sessions with and without hypotension to correlate the SO2 variability to hemodynamic instability. Our preliminary results showed an interesting, yet to be fully understood, role of SO2 in anticipating hypotension onset.","PeriodicalId":194782,"journal":{"name":"2008 Computers in Cardiology","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130302767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comparing symbolic representations of cardiac activity to identify patient populations with similar risk profiles","authors":"Z. Syed, B. Scirica, C.M. Stultz, J.V. Guttag","doi":"10.1109/CIC.2008.4748983","DOIUrl":"https://doi.org/10.1109/CIC.2008.4748983","url":null,"abstract":"This paper proposes electrocardiographic mismatch (ECGM) to quantify differences in the long-term ECG signals for two patients. ECGM compares the symbolic distributions of ECG signals and measures how different patients are electrocardiographically. Using ECGM, we propose a hierarchical clustering scheme that can identify patients in a population with anomalous ECG characteristics. When applied to a population of 686 patients suffering nonST-elevation ACS, our approach was able to identify patients at an increased risk of death and myocardial infarction (HR 2.8, p = 0.003) over a 90 day follow-up period.","PeriodicalId":194782,"journal":{"name":"2008 Computers in Cardiology","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130655286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
E. Bianchini, A. Corciu, L. Venneri, F. Faita, C. Giannarelli, V. Gemignani, M. Demi
{"title":"Assessment of cardiovascular risk markers from ultrasound images: System reproducibility","authors":"E. Bianchini, A. Corciu, L. Venneri, F. Faita, C. Giannarelli, V. Gemignani, M. Demi","doi":"10.1109/CIC.2008.4748988","DOIUrl":"https://doi.org/10.1109/CIC.2008.4748988","url":null,"abstract":"In this work the reproducibility of a system for the automatic assessment of carotid intima-media thickness and stiffness from ultrasound image sequences is evaluated. Sequences of the right/left common carotid arteries of 10 healthy volunteers were analyzed repeatedly in order to evaluate the reproducibility between observers and sessions; data were presented as the coefficients of variation. Results regarding the inter-observer and intra-observer intra-session variabilities were comparable. Intra-observer inter session variability was similar to those previously mentioned for the parameters which were derived directly from the B-mode image analysis, but larger for the others. The variability of the data obtained with the system is comparable to that reported in literature for other techniques used for the evaluation of the mechanical properties of large arteries. Thus, the reproducibility of our device, its low-cost and flexibility make it suitable for large population studies.","PeriodicalId":194782,"journal":{"name":"2008 Computers in Cardiology","volume":"116 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124255457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R. Cervigón, F. Castells, J. Moreno, J. Mateo, C. Sánchez, J. Millet
{"title":"Wavelet variance differences in atrial fibrillation during anaesthetic effect","authors":"R. Cervigón, F. Castells, J. Moreno, J. Mateo, C. Sánchez, J. Millet","doi":"10.1109/CIC.2008.4749118","DOIUrl":"https://doi.org/10.1109/CIC.2008.4749118","url":null,"abstract":"Effect of anaesthetic agents in restoration rhythm procedures during atrial fibrillation (AF) has not been fully investigated. We evaluated the effects of a widely used anaesthetic agent (propofol) in the fibrillation patterns. Intra-atrial recordings belong to 18 patients diagnosed with AF were analyzed ldquobeforerdquo (baseline) and ldquoduringrdquo anaesthetic infusion. The goal of this study is to characterize the variation in atrial properties along the atria in both states. The wavelet variance decomposes the variance of a time series on a scale by scale basis and hence has considerable appeal when physical phenomena are analyzed in terms of variations operating over a range of different scales. Moreover, the variance estimates are more accurately determined with a maximal-overlap version of the wavelet transform (MODWT). As mother wavelet was used the Haar wavelet where the signal was partitioned over seven scales. Wavelet analysis highlights a significant lower changes during the anaesthetic infusion respect to the basal conditions in the right atrium, with an opposite effect and non significant values in the left atrium. The proposed methodology provides an additional approach to the understanding of the role of the anaesthetic, showing a decrease in the variance inter-scales during the anaesthetic infusion in the right atrium, with the opposite effect in the left atrium.","PeriodicalId":194782,"journal":{"name":"2008 Computers in Cardiology","volume":"42 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123663455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
G. Wollny, M. Ledesma-Carbayo, P. Kellman, A. Santos
{"title":"Non-rigid motion compensation in free-breathing myocardial perfusion magnetic resonance imaging","authors":"G. Wollny, M. Ledesma-Carbayo, P. Kellman, A. Santos","doi":"10.1109/CIC.2008.4749079","DOIUrl":"https://doi.org/10.1109/CIC.2008.4749079","url":null,"abstract":"Breathing movements during the image acquisition of first-pass gadolinium enhanced, magnetic resonance imaging (MRI) hinder a direct automatic analysis of the myocardial perfusion. In addition, a qualitative readout by visual tracking is also more difficult as well. Non-rigid registration can be used to compensate for these movements in the image series. Because of the local contrast and intensity change over time, the registration method needs to be chosen carefully. We propose to make use of the periodicity of the breathing movement when patients are allowed to breath freely during image acquisition. Specifically, we propose to first identify a subset of the images that corresponds to the same phase of the breathing cycle and register these to compensate for the residual differences. By using a combination of normalised gradient fields and the sum of squared differences we circumvent the problems arising from the change of intensity. Then, for each of the remaining images, reference images of a similar intensity distribution are created by a linear combination of images from the align subset. In the last step, registration is achieved by minimising the sum of squared differences. Our first experiments show that this approach is well suited to compensate for the breathing movements.","PeriodicalId":194782,"journal":{"name":"2008 Computers in Cardiology","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123690660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Source separation of Foetal Heart Sounds and maternal activity from single-channel phonograms: A temporal independent component analysis approach","authors":"A. Jiménez-González, C.J. James","doi":"10.1109/CIC.2008.4749200","DOIUrl":"https://doi.org/10.1109/CIC.2008.4749200","url":null,"abstract":"Here we successfully extracted sources from noisy single-channel abdominal phonograms. First, an appropriate matrix of delays was constructed; then multiple independent components were calculated using TDSEP; finally, components were projected back onto the measurement space and grouped using K-means. Three single-channel phonograms from different subjects were analysed. Results showed a better-quality and more objective extraction of Foetal Heart Sounds (S1-S2), maternal activity and line-noise by using this temporal independent approach (versus a FastICA version). Future work will look for extracting more sources and a robust method to measure the quality of the extraction.","PeriodicalId":194782,"journal":{"name":"2008 Computers in Cardiology","volume":"6 9","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114110596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sumche Man, Arie C. Maan, M. Schalij, E. E. V. D. Wall, Cees A. Swenne
{"title":"T-wave alternans ranking: Striking disagreement between two vectorcardiographic measures of repolarization heterogeneity","authors":"Sumche Man, Arie C. Maan, M. Schalij, E. E. V. D. Wall, Cees A. Swenne","doi":"10.1109/CIC.2008.4749094","DOIUrl":"https://doi.org/10.1109/CIC.2008.4749094","url":null,"abstract":"In an attempt to study the importance of T-wave feature selection for T-wave alternans (TWA) analysis, we compared the alternans in two vectorcardiographic variables: maximal T-loop vector (MaxT) and the T-loop vector integral (Ti). We analyzed TWA in the 72 standard 12-lead ECGs comprised in the Physionet TWA challenge database with our research ECG/VCG processing program LEADS. We computed TWA by taking the absolute differences of the even and odd averaged beat values of Ti and MaxT (MaxT-TWA and Ti-TWA); also percentual alternans (%MaxT-TWA and %Ti-TWA) was computed. Finally, we computed both the Pearson and Kendall tau-b correlation coefficients between the MaxT-TWA and Ti-TWA, and between %MaxT-TWA and %Ti-TWA. All correlation coefficients differed significantly (P<0.01) from zero, but were relatively low (R=0.333-0.663). We conclude that T-wave features contain only in part common information; the selection of the T-wave feature in which TWA is computed deserves more attention.","PeriodicalId":194782,"journal":{"name":"2008 Computers in Cardiology","volume":"80 2","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"113987684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Bagno, R. Buselli, F. Anzil, V. Tarzia, V. Pengo, A. Ruggeri, T. Bottio, G. Gerosa
{"title":"In vitro characterization of bileaflet Mechanical Heart Valves closing sound","authors":"A. Bagno, R. Buselli, F. Anzil, V. Tarzia, V. Pengo, A. Ruggeri, T. Bottio, G. Gerosa","doi":"10.1109/CIC.2008.4749199","DOIUrl":"https://doi.org/10.1109/CIC.2008.4749199","url":null,"abstract":"Due to the asynchronous closure of the leaflets , the closing sound of a bileaflet Mechanical Hearth Valve (MHV) is characterised by the presence of two peaks in the time domain. The closing sounds of four commercial MHVs have been acquired in vitro using the Sheffield Pulse Duplicator, under different working conditions to simulate as many physiological ones. The MHVs closing sounds were detected by a commercial apparatus (Myotis 3c, Cardiosignal GmbH). Closing sound spectra (10-22 kHz) have been statistically analysed and compared. A preliminary classification of the tested MHVs is herewith presented; differences in their phonographic behaviour are briefly discussed. This work would allow moving towards the early phonocardiographic diagnosis of bileaflet MHVs malfunction due to endothelial pannus deposition and/or thrombosis.","PeriodicalId":194782,"journal":{"name":"2008 Computers in Cardiology","volume":"75 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114852159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
V. D’Errico, L. Potena, D. Fiore, F. Fabbri, F. Grigioni, G. Magnani, P. Ortolani, I. Bianchi, I. Corazza, R. Zannoli, A. Branzi
{"title":"Reproducibility of IVUS measurements in heart transplant recipients: Increased quality of data by using dedicated software for image analysis","authors":"V. D’Errico, L. Potena, D. Fiore, F. Fabbri, F. Grigioni, G. Magnani, P. Ortolani, I. Bianchi, I. Corazza, R. Zannoli, A. Branzi","doi":"10.1109/CIC.2008.4749097","DOIUrl":"https://doi.org/10.1109/CIC.2008.4749097","url":null,"abstract":"Cardiac allograft vasculopathy (CAV) is the major cause limiting long term graft survival after heart transplantation (HT), and is characterized by changes in coronary artery geometry, such as intimal thickening and vessel remodeling. Given the limited strategies available to reduce its impact on outcome, early diagnosis of CAV - for which intravascular ultrasound (IVUS) is the gold standard - is crucial to appropriately modulate therapy and to reduce contributing risk factors. However, a highly reproducible image-analysis method is required to capture the complex mechanisms beyond CAV-related changes in coronary geometry.","PeriodicalId":194782,"journal":{"name":"2008 Computers in Cardiology","volume":"2010 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114880176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}