{"title":"Eigen-vector based leads for reconstruction of the 12-lead electrocardiogram","authors":"D. Finlay, C. Nugent, M. Donnelly, S. Nelwan","doi":"10.1109/CIC.2008.4749053","DOIUrl":"https://doi.org/10.1109/CIC.2008.4749053","url":null,"abstract":"In this study we have developed a limited lead system to allow reconstruction of the 12-lead ECG. This has been based upon the analysis of eigen-vectors calculated from body surface potential map (BSPM) data. Eigenvectors were calculated from a set of 117 lead BSPMs (normal=172, LVH=178, MI=209). The extrema of the first three eigen-vectors were used to determine the positions of recording sites for three bipolar leads. These three bipolar leads were then used to reconstruct 12-lead ECGs recorded from an unseen group of subjects (normal = 57, LVH = 59, MI = 69). It was found that the suggested leads could reconstruct the 12-lead ECG with a median RMS error of 57.0 muV and a correlation coefficient of 0.968. This was in comparison to the EASI leads, which, when tested on the same data, produced a median RMS error of 60.1 muV and a correlation coefficient of 0.955. Following comparison on a lead-by-lead basis the eigen-vector based leads were found to perform particularly well in the reconstruction of the precordial leads V1-V5. Further work is required to refine and to determine the practical utility of the proposed leads in practice.","PeriodicalId":194782,"journal":{"name":"2008 Computers in Cardiology","volume":"515 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116218702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
L. Giorgis, Alfredo I. Hernandez, Amel Amblard, L. Senhadji, Serge, Cazeau, G. Jauvert, E. Donal
{"title":"Analysis of cardiac micro-acceleration signals for the estimation of systolic and diastolic time intervals in cardiac resynchronization therapy","authors":"L. Giorgis, Alfredo I. Hernandez, Amel Amblard, L. Senhadji, Serge, Cazeau, G. Jauvert, E. Donal","doi":"10.1109/CIC.2008.4749061","DOIUrl":"https://doi.org/10.1109/CIC.2008.4749061","url":null,"abstract":"Heart sounds, measured via cardiac micro-acceleration (CMA), carry valuable information about the mechanical and hemodynamic function of the heart. The aim of the present study is to estimate systolic and diastolic time intervals from CMA features, extracted by segmentation of the first two heart sounds, i.e. onset, maximum energy and end instants. CMA, ECG and echocardiographic audio signals were acquired simultaneously on 60 patients under different hemodynamic conditions. Linear models, fitted between CMA features and echo timings, were evaluated with their correlation coefficient, model error and coefficient stability. Models for mitral valve closing, aortic valve closing and opening instants showed satisfactory results, whereas the estimation of the opening instant of the mitral valve was more difficult. This work suggests the potential utility of CMA for monitoring cardiac function and defining optimal, adaptive pacing configurations.","PeriodicalId":194782,"journal":{"name":"2008 Computers in Cardiology","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134389532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R. Gregg, S.H. Zhou, J. Lindauer, E. Helfenbein, D. Feild
{"title":"Limitations on the Re-use of patient specific coefficients for 12-lead ECG reconstruction","authors":"R. Gregg, S.H. Zhou, J. Lindauer, E. Helfenbein, D. Feild","doi":"10.1109/CIC.2008.4749014","DOIUrl":"https://doi.org/10.1109/CIC.2008.4749014","url":null,"abstract":"Patient specific coefficients for reconstructing missing precordial leads (patient-specific single-use or PSS) show good performance but require a 12-lead ECG to start monitoring. A more convenient approach is either the use of population based coefficients (POP) or patient specific coefficients from an old 12-lead ECG (patient-specific multi-use or PSM). We used a data set of 1493 resting 12-lead ECGs from 224 patients. Waveform comparisons were made between recorded 12-lead and reconstructed cases using RMS difference. Three cases were compared, PSS, PSM and POP. Median RMS reconstruction error in the ST-T region was 16, 46 and 40 muV for lead configuration V1/V4 in the PSS, PSM and POP cases respectively. For the V2/V5 configuration, median ST-T RMS error was 8, 40 and 41 muV. The RMS error for the PSS case was lower and significantly better by paired T-test. The difference between the two more convenient use-models, PSM and POP, was not significant. Population based coefficients are preferred over patient-specific coefficients if the single-use use-model cannot be followed.","PeriodicalId":194782,"journal":{"name":"2008 Computers in Cardiology","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116931271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Graziano, C. Valzania, D. Bianchini, G. Loreti, I. Corazza, R. Zannoli
{"title":"Left ventricular resynchronization in H.F.: Comparison of alternative optimization methods","authors":"M. Graziano, C. Valzania, D. Bianchini, G. Loreti, I. Corazza, R. Zannoli","doi":"10.1109/CIC.2008.4748995","DOIUrl":"https://doi.org/10.1109/CIC.2008.4748995","url":null,"abstract":"This paper compares the results of two different procedures, Doppler Ultrasound and Transthoracic Impedance, to monitor the left ventricular stroke volume on a group of heart failure patients submitted to electrical resynchronization therapy. The two procedures have been applied in parallel on 9 patients by changing the stimulation delays between the septal and posterior ventricular walls and the results have been compared to evaluate the correlation between the two choices, and their sensitivity to detect the optimal stimulation condition. The results demonstrated a good agreement between the data obtained with the two procedures (R=0.82), but a very limited change of the target parameter (Stroke Volume) by changing the stimulation delay. This suggests doubts on the choice of stroke volume as the best parameter to be observed for the optimization process and on the adequate sensitivity of the two procedures to highlight the process.","PeriodicalId":194782,"journal":{"name":"2008 Computers in Cardiology","volume":"91 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126173410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
N. Greenberg, Z. Popović, G. Saracino, R. Grimm, J.D. Thomas
{"title":"Novel time-varying 3D display of wall motion, strain, strain rate and torsion for LV function assessment","authors":"N. Greenberg, Z. Popović, G. Saracino, R. Grimm, J.D. Thomas","doi":"10.1109/CIC.2008.4748967","DOIUrl":"https://doi.org/10.1109/CIC.2008.4748967","url":null,"abstract":"Advanced post processing of the standard acquisitions of echocardiographic data (i.e. 3 parallel short-axis views and 3 rotational long axis views) results in a total of 72 time-varying traces of segmental linear strains and 18 traces of segmental rotational data. If one separates the signal into endo, mid, and epicardial myocardial layers, a staggering 246 time-varying traces are available. The synthesis of this amount of data is extremely difficult. Our goal was to develop tools that can visualize this complex dataset in a single representation and use these tools to assess LV function in subjects to examine characteristic patterns.","PeriodicalId":194782,"journal":{"name":"2008 Computers in Cardiology","volume":"84 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116025669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Bernabeu, M. Bishop, J. Pitt-Francis, D. Gavaghan, V. Grau, B. Rodríguez
{"title":"High performance computer simulations for the study of biological function in 3D heart models incorporating fibre orientation and realistic geometry at para-cellular resolution","authors":"M. Bernabeu, M. Bishop, J. Pitt-Francis, D. Gavaghan, V. Grau, B. Rodríguez","doi":"10.1109/CIC.2008.4749143","DOIUrl":"https://doi.org/10.1109/CIC.2008.4749143","url":null,"abstract":"Information regarding the propagation dynamics of intramural electrical wavefronts in the 3D volume of the ventricles is critical in gaining a better understanding of normal and pathological cardiac function. However, investigation into such phenomena using cardiac modelling has so far been impaired due to limitations in the structural details included in current cardiac computational models. Here, we describe the technological pipeline required for the construction of realistic, highly-detailed and personalised whole ventricular models directly from high-resolution MR images and their use within a reliable, fully tested cardiac simulation software (Chaste). Simulations of cardiac propagation in the structurally-detailed model are presented that reveal the importance of complex structural geometry, fibre orientation, blood vessels and other heterogeneities in propagation of activation wavefronts through the ventricular volume. The tools and techniques presented in this study are expected to be key in the development and application of the next generation of cardiac models.","PeriodicalId":194782,"journal":{"name":"2008 Computers in Cardiology","volume":"28 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116108144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Implicit comparison of accuracy of heart rate variability spectral measures estimated via heart rate and heart period signals","authors":"A. I. Maistrou","doi":"10.1109/CIC.2008.4749101","DOIUrl":"https://doi.org/10.1109/CIC.2008.4749101","url":null,"abstract":"In this article an overview of existing signals for evaluation of HRV spectral domain measures is made. Functional dependency between heart rate and heart period signals has been analyzed. Artificial data series have been used to extract features of spectra estimated via heart rate and heart period signals. Criteria for choosing between mentioned signals has been introduced and discussed. Implicit comparison of distortions of spectral measures estimation has been tested on ldquoFantasiardquo database (Physionet.org). Statistical analysis of differences between calculated spectral HRV measures obtained using heart rate and heart period signals has been presented.","PeriodicalId":194782,"journal":{"name":"2008 Computers in Cardiology","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128211730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
K. Berškienė, A. Vainoras, A. Daunoravičienė, V. Sedekerskiene, S. Korsakas, V. Jurkonis
{"title":"Complexity assessment of ECG RR interval","authors":"K. Berškienė, A. Vainoras, A. Daunoravičienė, V. Sedekerskiene, S. Korsakas, V. Jurkonis","doi":"10.1109/CIC.2008.4749210","DOIUrl":"https://doi.org/10.1109/CIC.2008.4749210","url":null,"abstract":"Physical load is very important and necessary for human organism and for its systems functionality. During bicycle ergometry work we can evaluate the functionality of the human organism. We looked for the complexity measure, which could integrally and simple evaluate organism reaction to physical load. We used ECG RR interval allometric relation and RR interval information dimension. We indicated, that the slope of ECG RR interval allometric relation and information dimension could be used as the RR interval complexity measures, defining all organism reaction to physical load. The study showed that young women RR interval complexity is higher, it means that all organism adaptation to physical load is better, different organism systems better interact together. Significant differences between load and recovery periods detected different adaptation complexity levels.","PeriodicalId":194782,"journal":{"name":"2008 Computers in Cardiology","volume":"35 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128285140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R. Balocchi, G. Paoletti, E. Santarcangelo, E. Scattina, L. Sebastiani, A. Macerata, M. Varanini
{"title":"Hypnotizability dependent autonomic modulation during a low attentional task","authors":"R. Balocchi, G. Paoletti, E. Santarcangelo, E. Scattina, L. Sebastiani, A. Macerata, M. Varanini","doi":"10.1109/CIC.2008.4749206","DOIUrl":"https://doi.org/10.1109/CIC.2008.4749206","url":null,"abstract":"Hypnotizability-dependent changes in heart rate and blood pressure in the time domain were studied during low attentional tasks in subjects with high or low hypnotic susceptibility watching a relaxing and an alerting movie. All participants reported relaxation during the former, while only part of them was stressed by the latter. During relaxation hypnotizability did not modulate mean heart rate and blood pressure, but affected the variability of the latter, which indirectly indicates differences in the autonomic pattern associated with the low attentional relaxing movie with respect to simple relaxation and highlighted the hypnotizability-related role of the emotional content associated with a relaxation response. In line with previous studies the results suggested a role for hypnotizability in the control of the vascular resistance.","PeriodicalId":194782,"journal":{"name":"2008 Computers in Cardiology","volume":"52 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128978060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
V. Donis, M. Guillem, A. Climent, F. Castells, F. Chorro, J. Millet
{"title":"Diagnosis of Bundle Branch Block by analyzing body surface potential maps","authors":"V. Donis, M. Guillem, A. Climent, F. Castells, F. Chorro, J. Millet","doi":"10.1109/CIC.2008.4748986","DOIUrl":"https://doi.org/10.1109/CIC.2008.4748986","url":null,"abstract":"Bundle Branch Block (BBB) is a heart disease which is diagnosed by the analysis of the ECG morphology and the duration of the QRS complex. As Body Surface Potential Mapping provides more information than 12- lead ECG, this study aims to check whether studying mapping information BBB diagnosis can be improved. Representative maps of Left BBB and of healthy subjects were obtained. Comparisons between these maps and the maps of individual subjects were made in order to check whether the results would provide a correct classification of the subjects. Specificity was 100% for both groups. Sensitivity was 100% for LBBB patients and 89% for healthy subjects. The study concluded that ventricular depolarization in subjects with the same diagnosis have a similar pattern. With the quantitative analysis proposed, BBB patterns can be distinguished more easily than by visual inspection of the standard ECG, therefore improving BBB diagnosis.","PeriodicalId":194782,"journal":{"name":"2008 Computers in Cardiology","volume":"31 6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129328426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}