NeoReviewsPub Date : 2026-07-01DOI: 10.1542/neo.27-7-032
Siddharth Hariharan, Logan P Todhunter, Stefanie J Hollenbach
{"title":"A Pregnant Person Requiring Medical Intensive Care Unit Management of Asthma.","authors":"Siddharth Hariharan, Logan P Todhunter, Stefanie J Hollenbach","doi":"10.1542/neo.27-7-032","DOIUrl":"https://doi.org/10.1542/neo.27-7-032","url":null,"abstract":"","PeriodicalId":19465,"journal":{"name":"NeoReviews","volume":"27 7","pages":"e452-e455"},"PeriodicalIF":0.0,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148361902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
NeoReviewsPub Date : 2026-07-01DOI: 10.1542/neo.27-7-026
Pragnesh Parmar, Gunvanti Rathod
{"title":"Legal Rights of Neonates in India: Birth Concealment, Abandonment, and Safe Surrender.","authors":"Pragnesh Parmar, Gunvanti Rathod","doi":"10.1542/neo.27-7-026","DOIUrl":"10.1542/neo.27-7-026","url":null,"abstract":"<p><p>Neonatal abandonment, concealment of birth, and unsafe surrender, which is defined as relinquishment of a newborn in unprotected, nonmedical settings such as public places, refuse sites, or private locations without supervision or care, remain persistent public health and medico-legal challenges in India. These events occur as the result of a combination of poverty, gender bias, social stigma, perinatal mental-health vulnerability, and gaps in accessible maternal support. For clinicians, immediate priorities include resuscitation, safeguarding the infant, ensuring systematic and accurate documentation, and in India, initiating mandatory reporting. In this review, we provide an overview of India's current legal framework and summarize evolving safe surrender initiatives, clinical and forensic challenges, and recommended strategies to reduce harm; comparison with approaches in other countries is also included. A rights-based approach, along with institutional protocols and perinatal mental-health services, may reduce preventable neonatal morbidity and mortality while supporting vulnerable mothers in India.</p>","PeriodicalId":19465,"journal":{"name":"NeoReviews","volume":"27 7","pages":"e407-e413"},"PeriodicalIF":0.0,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148361843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
NeoReviewsPub Date : 2026-07-01DOI: 10.1542/neo.27-7-029
Anastasia M Kahan, Michelle J Yang, Martha A Monson, Janice L B Bryne, Anne M Kennedy, Paula J Woodward, Michael D Traynor, Katie W Russell, Stephen J Fenton
{"title":"Giant Omphalocele.","authors":"Anastasia M Kahan, Michelle J Yang, Martha A Monson, Janice L B Bryne, Anne M Kennedy, Paula J Woodward, Michael D Traynor, Katie W Russell, Stephen J Fenton","doi":"10.1542/neo.27-7-029","DOIUrl":"10.1542/neo.27-7-029","url":null,"abstract":"<p><p>Omphalocele is the second most common congenital abdominal wall defect, affecting approximately 1 to 2 per 10 000 live births, and it requires intensive neonatal care at birth. Omphalocele is characterized by herniation of abdominal viscera into a membranous sac through a defect at the umbilical ring. Giant omphalocele (GO) is a subset of this condition and is generally defined as a defect measuring at least 5 cm in diameter or one that contains evisceration of at least 50% of the liver into the sac. The pathophysiology of GO is thought to involve a complex interplay of failure of the lateral abdominal folds to close during embryogenesis and of bowel loops to return to the abdominal cavity. This results in persistent herniation of the abdominal contents into the base of the umbilical cord between the 6th and 11th weeks of development. GO is typically diagnosed prenatally by fetal ultrasonography and requires multidisciplinary care between high-risk obstetrics, neonatology, and pediatric surgery. In this review, we discuss the prenatal, neonatal, and surgical management, as well as long-term outcomes of patients with GO.</p>","PeriodicalId":19465,"journal":{"name":"NeoReviews","volume":"27 7","pages":"e433-e444"},"PeriodicalIF":0.0,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148361888","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"An Unusual Cause of Recurrent Escherichia coli Meningitis in a Preterm Infant.","authors":"Pradeep Ramishetty, Ravali Vogeti, Sai Kiran Deshabhotla, Tejo Pratap Oleti, Vijay Yeldandi","doi":"10.1542/neo.27-7-031","DOIUrl":"https://doi.org/10.1542/neo.27-7-031","url":null,"abstract":"","PeriodicalId":19465,"journal":{"name":"NeoReviews","volume":"27 7","pages":"e448-e451"},"PeriodicalIF":0.0,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148361840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
NeoReviewsPub Date : 2026-07-01DOI: 10.1542/neo.27-7-027
Shelley M Lawrence, Maria Elisabeth Moreira, Josef Neu
{"title":"Postnatal Cytomegalovirus Risk Does Not Outweigh the Benefits of Mother's Raw Milk.","authors":"Shelley M Lawrence, Maria Elisabeth Moreira, Josef Neu","doi":"10.1542/neo.27-7-027","DOIUrl":"10.1542/neo.27-7-027","url":null,"abstract":"<p><p>Human cytomegalovirus (CMV) establishes lifelong infection, and there is currently no vaccine or cure. Postnatally, infants can acquire the virus by consuming raw breast milk (BM) from seropositive mothers. Most of these infections are asymptomatic and do not result in either short- or long-term adverse health problems. However, preterm infants can experience significant illness, with severity inversely related to their gestational age at the time of infection. Given the risk of symptomatic disease, empirical treatments to prevent viral transmission in BM have been advocated. However, the American Academy of Pediatrics and the World Health Organization recommend feeding preterm infants their mother's raw BM because the health benefits outweigh the risks associated with postnatally acquired CMV infection. This review discusses the health advantages of providing raw mother's BM to preterm infants. It also explains how milk sterilization procedures can alter its nutritional content, leading to impaired growth and increased morbidity in this patient population. Furthermore, it details postnatal CMV infection in preterm infants, including known clinical findings, treatment recommendations, and potential outcomes.</p>","PeriodicalId":19465,"journal":{"name":"NeoReviews","volume":"27 7","pages":"e414-e424"},"PeriodicalIF":0.0,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148361905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
NeoReviewsPub Date : 2026-06-01DOI: 10.1542/neo.27-6-024
Anita Singh, Kirti M Naranje
{"title":"Inguinal Swelling in a Neonate.","authors":"Anita Singh, Kirti M Naranje","doi":"10.1542/neo.27-6-024","DOIUrl":"https://doi.org/10.1542/neo.27-6-024","url":null,"abstract":"","PeriodicalId":19465,"journal":{"name":"NeoReviews","volume":"27 6","pages":"e390-e393"},"PeriodicalIF":0.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148138553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
NeoReviewsPub Date : 2026-06-01DOI: 10.1542/neo.27-6-022
Kayla Solstad, John Chatterton, Abby Montague, Andrea Lampland
{"title":"When Is a Gray Baby Not a \"Gray Baby\"?","authors":"Kayla Solstad, John Chatterton, Abby Montague, Andrea Lampland","doi":"10.1542/neo.27-6-022","DOIUrl":"https://doi.org/10.1542/neo.27-6-022","url":null,"abstract":"","PeriodicalId":19465,"journal":{"name":"NeoReviews","volume":"27 6","pages":"e382-e384"},"PeriodicalIF":0.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148138532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
NeoReviewsPub Date : 2026-06-01DOI: 10.1542/neo.27-6-019
Abby C Larson, Jason Gien, S Christopher Derderian
{"title":"Evolving Approaches to Congenital Diaphragmatic Hernia Management.","authors":"Abby C Larson, Jason Gien, S Christopher Derderian","doi":"10.1542/neo.27-6-019","DOIUrl":"10.1542/neo.27-6-019","url":null,"abstract":"<p><p>Congenital diaphragmatic hernia (CDH) is a complex developmental anomaly characterized by pulmonary hypoplasia, abnormal pulmonary vascular development, and variable cardiac dysfunction. Due to advances in neonatal intensive care, center expertise, and surgical repair after physiologic stability, mortality has improved over the past few decades, with survival rates in isolated mild to moderate cases approaching 75% to 90%. This review synthesizes contemporary evidence across the continuum of care for CDH: prenatal diagnosis and imaging; fetal intervention, including fetoscopic endoluminal tracheal occlusion (FETO); delivery planning; postnatal stabilization; ventilatory and hemodynamic management; extracorporeal membrane oxygenation (ECMO); surgical repair; postoperative care; chronic morbidity; and survivorship. Emerging areas include precision prenatal risk stratification, refinement of FETO, harmonized ECMO and surgical guidelines, and long-term multidisciplinary models of care.</p>","PeriodicalId":19465,"journal":{"name":"NeoReviews","volume":"27 6","pages":"e337-e354"},"PeriodicalIF":0.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148138586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
NeoReviewsPub Date : 2026-06-01DOI: 10.1542/neo.27-6-018
Connor Hesher, Susan Henderson-Sears, Zeynep N I Salih
{"title":"Parent Perspective: Caregivers' Experiences With Home Tube Feedings in Infants.","authors":"Connor Hesher, Susan Henderson-Sears, Zeynep N I Salih","doi":"10.1542/neo.27-6-018","DOIUrl":"https://doi.org/10.1542/neo.27-6-018","url":null,"abstract":"","PeriodicalId":19465,"journal":{"name":"NeoReviews","volume":"27 6","pages":"e331-e336"},"PeriodicalIF":0.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148138571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}