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Pallister-Killian Syndrome. 帕利斯特-基利安综合征
NeoReviews Pub Date : 2024-11-01 DOI: 10.1542/neo.25-11-e751
Ritu Chitkara, Valerie Chock, Richard Barth, Hisham Dahmoush, Carly Smith, Dena R Matalon, Melissa Herring, Susan Hintz
{"title":"Pallister-Killian Syndrome.","authors":"Ritu Chitkara, Valerie Chock, Richard Barth, Hisham Dahmoush, Carly Smith, Dena R Matalon, Melissa Herring, Susan Hintz","doi":"10.1542/neo.25-11-e751","DOIUrl":"https://doi.org/10.1542/neo.25-11-e751","url":null,"abstract":"","PeriodicalId":19465,"journal":{"name":"NeoReviews","volume":"25 11","pages":"e751-e756"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142558343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Unusual Dermatologic Findings in an Extremely Low Birthweight Infant: The Genetic Diagnosis. 极低出生体重儿的异常皮肤症状：遗传诊断。
NeoReviews Pub Date : 2024-11-01 DOI: 10.1542/neo.25-11-e747
L Elizabeth Ricker, Matthew Saxonhouse, Lauren Carter
{"title":"Unusual Dermatologic Findings in an Extremely Low Birthweight Infant: The Genetic Diagnosis.","authors":"L Elizabeth Ricker, Matthew Saxonhouse, Lauren Carter","doi":"10.1542/neo.25-11-e747","DOIUrl":"https://doi.org/10.1542/neo.25-11-e747","url":null,"abstract":"","PeriodicalId":19465,"journal":{"name":"NeoReviews","volume":"25 11","pages":"e747-e750"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142558347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Alloimmunization in Pregnancy: Implications for the Fetus and Neonate. 妊娠期同种免疫：对胎儿和新生儿的影响。
NeoReviews Pub Date : 2024-11-01 DOI: 10.1542/neo.25-11-e742
Scott N MacGregor
{"title":"Alloimmunization in Pregnancy: Implications for the Fetus and Neonate.","authors":"Scott N MacGregor","doi":"10.1542/neo.25-11-e742","DOIUrl":"https://doi.org/10.1542/neo.25-11-e742","url":null,"abstract":"<p><p>Blood group or red cell alloimmunization occurs when a pregnant patient has produced antibodies to a blood group antigen possessed by the fetus and not possessed by the pregnant patient. Maternal antibodies are usually produced as an immune response to fetal-maternal bleeding or blood product transfusion. Prevention remains the most important strategy to avoid the formation of maternal antibodies or alloimmunization. Maternal alloimmunization may result in transplacental passage of these antibodies into the fetal circulation and the potential for fetal or neonatal hemolysis and anemia. Red cell alloimmunization can result in significant perinatal morbidity and mortality. Management of alloimmunization in pregnant patients should be protocol-driven. Current strategies for assessment and therapies allow for more thorough and less invasive management with risks to mother and fetus.</p>","PeriodicalId":19465,"journal":{"name":"NeoReviews","volume":"25 11","pages":"e742-e746"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142558340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Term Neonate With Right-Sided Limb Swelling: A Potpourri of Etiology and Complication. 右侧肢体肿胀的足月新生儿：病因和并发症杂烩。
NeoReviews Pub Date : 2024-11-01 DOI: 10.1542/neo.25-11-e729
Tehsin Patel, Abhilasha Kumari, Prashanth Ranya Raghavendra, Sruthi Nair, Anitha Haribalakrishna, Sumeet Anant Dhulshette, Hemangini Thakkar, Patil Varun Praveen, Shivam Sushilkumar Shukla
{"title":"Term Neonate With Right-Sided Limb Swelling: A Potpourri of Etiology and Complication.","authors":"Tehsin Patel, Abhilasha Kumari, Prashanth Ranya Raghavendra, Sruthi Nair, Anitha Haribalakrishna, Sumeet Anant Dhulshette, Hemangini Thakkar, Patil Varun Praveen, Shivam Sushilkumar Shukla","doi":"10.1542/neo.25-11-e729","DOIUrl":"https://doi.org/10.1542/neo.25-11-e729","url":null,"abstract":"","PeriodicalId":19465,"journal":{"name":"NeoReviews","volume":"25 11","pages":"e729-e736"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142558345","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hemoglobinopathies in the Neonate. 新生儿血红蛋白病。
NeoReviews Pub Date : 2024-11-01 DOI: 10.1542/neo.25-11-e720
Katrina Blankenhorn, Kaitlin Strumph
{"title":"Hemoglobinopathies in the Neonate.","authors":"Katrina Blankenhorn, Kaitlin Strumph","doi":"10.1542/neo.25-11-e720","DOIUrl":"https://doi.org/10.1542/neo.25-11-e720","url":null,"abstract":"<p><p>Hemoglobinopathies in neonates constitute a group of disorders influenced by genetic mutations in the human globin genes. They are often broadly categorized into quantitative defects or qualitative defects, though they are not mutually exclusive. In quantitative defects, the mutation causes insufficient production of a normal globin chain, which can range from no production to mild deficiency. These are typically referred to as thalassemias. In qualitative defects, the structure of the hemoglobin is altered. The most common structural hemoglobinopathy is sickle cell disease. During fetal development, distinct globin chains are synthesized, which undergo a progressive switch to adult globin chains perinatally. This affects the timing of the clinical presentation of these disorders and thus, our ability to diagnose them. In this review, we focus on the epidemiology, genetic causes, clinical presentation, and general overview and management of common hemoglobin disorders that may be encountered in the neonatal period.</p>","PeriodicalId":19465,"journal":{"name":"NeoReviews","volume":"25 11","pages":"e720-e728"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142558342","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Neonate with Refractory Seizures. 一名患有难治性癫痫的新生儿
NeoReviews Pub Date : 2024-10-01 DOI: 10.1542/neo.25-10-e652
Prashanth Somaraj Urs, Gurucharan Adoor, Basila Thekkeveettil, Anup Ithihas
{"title":"A Neonate with Refractory Seizures.","authors":"Prashanth Somaraj Urs, Gurucharan Adoor, Basila Thekkeveettil, Anup Ithihas","doi":"10.1542/neo.25-10-e652","DOIUrl":"10.1542/neo.25-10-e652","url":null,"abstract":"","PeriodicalId":19465,"journal":{"name":"NeoReviews","volume":"25 10","pages":"e652-e655"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142351108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Perioperative Quality Improvement in Children's Hospitals Neonatal Consortium NICUs. 儿童医院新生儿联盟新生儿重症监护室围手术期质量改进。
NeoReviews Pub Date : 2024-10-01 DOI: 10.1542/neo.25-10-e601
Thomas Bartman, Priscilla Joe, Laurel Moyer
{"title":"Perioperative Quality Improvement in Children's Hospitals Neonatal Consortium NICUs.","authors":"Thomas Bartman, Priscilla Joe, Laurel Moyer","doi":"10.1542/neo.25-10-e601","DOIUrl":"https://doi.org/10.1542/neo.25-10-e601","url":null,"abstract":"<p><p>Infants admitted to NICUs in children's hospitals represent a different population than those in a traditional birth hospital. The patients in a children's hospital NICU often have the most complex neonatal diagnoses and are cared for by various subspecialists. The Children's Hospitals Neonatal Consortium is a collaborative of more than 40 NICUs that collect data and perform quality improvement (QI) work across the United States and Canada. The collaborative's database provides an opportunity to benchmark clinical outcomes for this specialized population and to support the QI efforts. In this review, we summarize the success of individual collaborative QI projects focused on improving the care of the neonate in the perioperative period related to clinical team handoffs, postoperative hypothermia prevention, and improvement of postoperative pain management. The collaborative's experience can serve as a model for other national collaboratives seeking to support QI efforts.</p>","PeriodicalId":19465,"journal":{"name":"NeoReviews","volume":"25 10","pages":"e601-e611"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142351113","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Delivery Room Management of Infants with Surgical Conditions. 手术婴儿的产房管理。
NeoReviews Pub Date : 2024-10-01 DOI: 10.1542/neo.25-10-e612
K Taylor Wild, Anne M Ades, Holly L Hedrick, Lauren Heimall, Julie S Moldenhauer, Olivia Nelson, Elizabeth E Foglia, Natalie E Rintoul
{"title":"Delivery Room Management of Infants with Surgical Conditions.","authors":"K Taylor Wild, Anne M Ades, Holly L Hedrick, Lauren Heimall, Julie S Moldenhauer, Olivia Nelson, Elizabeth E Foglia, Natalie E Rintoul","doi":"10.1542/neo.25-10-e612","DOIUrl":"https://doi.org/10.1542/neo.25-10-e612","url":null,"abstract":"<p><p>Delivery room resuscitation of infants with surgical conditions can be complex and depends on an experienced and cohesive multidisciplinary team whose performance is more important than that of any individual team member. Existing resuscitation algorithms were not developed for infants with congenital anomalies, and delivery room resuscitation is largely dictated by expert opinion extrapolating physiologic expectations from infants without anomalies. As prenatal diagnosis rates improve, there is an increased ability to plan for the unique delivery room needs of infants with surgical conditions. In this review, we share expert opinion, including our center's delivery room management for neonatal noncardiac surgical conditions, and highlight knowledge gaps and the need for further studies and evidence-based practice to be incorporated into the delivery room care of infants with surgical conditions. Future research in this area is essential to move from an expert-based approach to a data-driven approach to improve and individualize delivery room resuscitation of infants with surgical conditions.</p>","PeriodicalId":19465,"journal":{"name":"NeoReviews","volume":"25 10","pages":"e612-e633"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142351111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Neonate with Anemia and Diarrhea. 一名患有贫血和腹泻的新生儿。
NeoReviews Pub Date : 2024-10-01 DOI: 10.1542/neo.25-10-e648
Trusha More, Sruthi Nair, Shweta Mhatre, Prashanth Ranya Raghavendra, Anitha Haribalakrishna
{"title":"A Neonate with Anemia and Diarrhea.","authors":"Trusha More, Sruthi Nair, Shweta Mhatre, Prashanth Ranya Raghavendra, Anitha Haribalakrishna","doi":"10.1542/neo.25-10-e648","DOIUrl":"https://doi.org/10.1542/neo.25-10-e648","url":null,"abstract":"","PeriodicalId":19465,"journal":{"name":"NeoReviews","volume":"25 10","pages":"e648-e651"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142351107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cutting into the NICU: Improvements in Outcomes for Neonates with Surgical Conditions. 切入新生儿重症监护室：改善手术新生儿的治疗效果。
NeoReviews Pub Date : 2024-10-01 DOI: 10.1542/neo.25-10-e634
Stephanie L Bourque, Karna Murthy, Theresa R Grover, Loren Berman, Stefanie Riddle
{"title":"Cutting into the NICU: Improvements in Outcomes for Neonates with Surgical Conditions.","authors":"Stephanie L Bourque, Karna Murthy, Theresa R Grover, Loren Berman, Stefanie Riddle","doi":"10.1542/neo.25-10-e634","DOIUrl":"https://doi.org/10.1542/neo.25-10-e634","url":null,"abstract":"<p><p>The Children's Hospitals Neonatal Consortium (CHNC), established in 2010, seeks to improve care for infants with medically and surgically complex conditions who are cared for in level IV regional children's hospital NICUs across North America. Through patient-level individual data collection, comparative benchmarking, and multicenter quality improvement work, CHNC has contributed to knowledge and improved outcomes, leveraging novel collaborations between and across institutions. Focusing on antenatal and inpatient care for infants with surgical conditions including congenital diaphragmatic hernia, gastroschisis, and necrotizing enterocolitis, we summarize the progress made in these infants' care. We highlight the ways in which CHNC has enabled multidisciplinary and multicenter collaborations through the facilitation of diagnosis-specific focus groups, which enable comparative observations of outcomes through quality improvement and research initiatives. Finally, we review the importance of postbirth hospitalization needs of these infants and the application of telemedicine in this population.</p>","PeriodicalId":19465,"journal":{"name":"NeoReviews","volume":"25 10","pages":"e634-e647"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142351110","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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