NeoReviews Pub Date : 2025-08-01 DOI: 10.1542/neo.26-8-041

Mishu Mangla, Seetu Palo, Rohini Motwani, Annapurna Srirambhatla, Naina Kumar

{"title":"Virtual Autopsy in Perinatal Pathology: Current Practices and the Need for Standardization.","authors":"Mishu Mangla, Seetu Palo, Rohini Motwani, Annapurna Srirambhatla, Naina Kumar","doi":"10.1542/neo.26-8-041","DOIUrl":"https://doi.org/10.1542/neo.26-8-041","url":null,"abstract":"Fetal/neonatal autopsy remains a cornerstone in the evaluation of perinatal losses, offering valuable insights into the causes of death. Couples may decline fetal/neonatal autopsy because of emotional distress, a wish to preserve their child's physical integrity, or cultural and religious beliefs, including body sanctity and burial traditions. Virtual autopsy, also known as virtopsy, has emerged as a promising noninvasive alternative to traditional autopsy techniques. However, the lack of standardized protocols limits their widespread adoption and comparability across studies. In this review, we aim to explore the current state of virtual autopsy techniques, emphasizing their utility in fetal and neonatal pathology. Key challenges include imaging parameters, data interpretation, and integration with clinical findings. These are highlighted. Furthermore, we propose a framework for developing standardized virtual autopsy protocols to improve reproducibility. By addressing these gaps, this review aims to contribute to the establishment of best practices, ultimately advancing the field of fetal and perinatal pathology.","PeriodicalId":19465,"journal":{"name":"NeoReviews","volume":"26 8","pages":"e524-e534"},"PeriodicalIF":0.0,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144760643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Acute Liver Failure in a Neonate. 新生儿急性肝功能衰竭1例。

NeoReviews Pub Date : 2025-08-01 DOI: 10.1542/neo.26-8-044

Amee Amin, Scott Osborne, Geoffrey A Preidis, Sharada H Gowda

引用次数: 0

Tracheobronchomalacia in an Infant With Severe Bronchopulmonary Dysplasia. 严重支气管肺发育不良婴儿的气管支气管软化症。

NeoReviews Pub Date : 2025-08-01 DOI: 10.1542/neo.26-8-049

Gangaram Akangire, Karishma Rao, Addie Begley, Charisse Lachica, Winston Manimtim

引用次数: 0

Preterm Newborn With Blue Abdominal Discoloration on the First Newborn Day. 早产新生儿在出生第一天出现蓝色腹部变色。

NeoReviews Pub Date : 2025-08-01 DOI: 10.1542/neo.26-8-047

Andrew Beverstock, Pamela M Ketwaroo, Michelle H Lucena

引用次数: 0

Psychosis in Pregnancy and the Neonatal Ripple Effect. 妊娠期精神病和新生儿连锁反应。

NeoReviews Pub Date : 2025-08-01 DOI: 10.1542/neo.26-8-046

Alyssa Yeung, Deepthisri Suresh, Carly Hirschberg

{"title":"Psychosis in Pregnancy and the Neonatal Ripple Effect.","authors":"Alyssa Yeung, Deepthisri Suresh, Carly Hirschberg","doi":"10.1542/neo.26-8-046","DOIUrl":"https://doi.org/10.1542/neo.26-8-046","url":null,"abstract":"Background: Postpartum mood disorders including depression and psychosis are well documented conditions. However, new-onset psychosis in pregnancy is less common and less well studied with fewer reports available.Clinical case: A 36-year-old Gravida 6 Para 3113, non-English-speaking patient with no known history of mood disorder outside of pregnancy presented for her scheduled repeat cesarean delivery and was diagnosed with new-onset peripartum psychosis. She was admitted to the antepartum service and underwent an extensive workup to rule out organic causes, which all returned negative results. The patient was initially medically managed, and her mental status improved to where she was able to assent for her cesarean delivery while consent was obtained from the patient's next of kin. After delivery the patient and neonate continued to be managed with an interdisciplinary team to ensure the safety of mother and child. The neonate was transferred to the newborn nursey with supervised visits with the patient and was ultimately discharged home with the father. The patient was managed inpatient on the postpartum floor; however, she ultimately required transfer to an inpatient psychiatry unit where she received higher-level psychiatric care until she improved and was cleared to go home with close outpatient follow-up.Conclusion: This is one of the few published cases of new-onset psychosis in pregnancy. It highlights the importance of addressing mental health concerns in our patients as well as the vital interdisciplinary team management to ensure the safety of our patients and their families. The paucity of data around these presentations is notable and there exists an opportunity for further investigation into mental health and reproductive psychiatry to help improve outcomes.","PeriodicalId":19465,"journal":{"name":"NeoReviews","volume":"26 8","pages":"e568-e572"},"PeriodicalIF":0.0,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144760641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Congenital Lymphatic Malformations. 先天性淋巴畸形。

NeoReviews Pub Date : 2025-08-01 DOI: 10.1542/neo.26-8-048

Katelyn Seither, DonnaMaria E Cortezzo, David McKinney, Kiersten Ricci, Stefanie Riddle

引用次数: 0

Human Milk Banking and Donor Milk: Effect on Growth and Nutrition in the NICU. 人乳库和供体乳：对新生儿重症监护室生长和营养的影响。

NeoReviews Pub Date : 2025-08-01 DOI: 10.1542/neo.26-8-042

Kimberly Mannebach, Jennifer Hanford

引用次数: 0

Persistent Failed Extubation in a 29-Week Preterm Neonate. 29周早产儿持续拔管失败一例。

NeoReviews Pub Date : 2025-08-01 DOI: 10.1542/neo.26-8-045

Tito Andrés Ortega Toro, John Velásquez, Jenny Eraso, Carlos Villamil, Yaqueline Melo, Juliana Vesga Zamudio