NeoReviewsPub Date : 2026-09-01DOI: 10.1542/neo.27-9-051
Kristen Schaffer, Katherine Lopez-Lepe, Henry C Lee, Nana Matoba
{"title":"Outcomes and Care Needs of Infants Born to Individuals Incarcerated During Pregnancy.","authors":"Kristen Schaffer, Katherine Lopez-Lepe, Henry C Lee, Nana Matoba","doi":"10.1542/neo.27-9-051","DOIUrl":"10.1542/neo.27-9-051","url":null,"abstract":"<p><p>The rapid growth of incarceration of women in the United States has been accompanied by an increase in the number of pregnant individuals experiencing incarceration. Pregnant individuals in prisons and jails are at a higher risk for poor perinatal health outcomes. Existing data on these outcomes are limited, and research often only reflects single institutions or geographic regions. There is currently no consistent nationwide tracking system, and most existing research focuses solely on maternal health outcomes. To address this gap, this review centers on infant outcomes among those born to individuals incarcerated during pregnancy. We provide an overview of maternal incarceration and outcomes, explore what is currently known about infant outcomes, and examine policies and programs that influence infant health, specifically those related to lactation support, prison nursery programs, community-based initiatives, and alternative sentencing. Finally, we offer practical recommendations for clinicians caring for maternal-infant dyads affected by incarceration, including how clinicians can play a critical role in advocating both for individual patients and for policy change at the local, state, and national level.</p>","PeriodicalId":19465,"journal":{"name":"NeoReviews","volume":"27 9","pages":"e542-e554"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148866173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
NeoReviewsPub Date : 2026-09-01DOI: 10.1542/neo.27-9-046
Mary Marchese, Nina K Ayala
{"title":"When the Valve Narrows: Maternal and Neonatal Implications of Aortic Stenosis in Pregnancy.","authors":"Mary Marchese, Nina K Ayala","doi":"10.1542/neo.27-9-046","DOIUrl":"https://doi.org/10.1542/neo.27-9-046","url":null,"abstract":"","PeriodicalId":19465,"journal":{"name":"NeoReviews","volume":"27 9","pages":"e589-e593"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148866234","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
NeoReviewsPub Date : 2026-09-01DOI: 10.1542/neo.27-9-049
Bianca R Davis, Nicole V Sewall, Akshaya J Vachharajani
{"title":"Surfactant in Late Preterm Infants.","authors":"Bianca R Davis, Nicole V Sewall, Akshaya J Vachharajani","doi":"10.1542/neo.27-9-049","DOIUrl":"https://doi.org/10.1542/neo.27-9-049","url":null,"abstract":"<p><p>Despite an incidence ranging from 8% to 30.6% across various studies, a lack of guidelines about the management of respiratory distress syndrome (RDS) in late preterm infants (LPIs) exists. Clinical criteria for surfactant therapy and mode of administration remain highly variable in this population. Although surfactant administration is time-sensitive, there is no clear consensus among clinicians on the optimal timing of administration in LPIs. In this review, we summarize the current evidence of the role of antenatal steroids in the prevention of RDS in LPIs, examine current understanding of the pathophysiology of RDS in this population, and review clinical criteria, ideal timing, and mode of surfactant administration.</p>","PeriodicalId":19465,"journal":{"name":"NeoReviews","volume":"27 9","pages":"e571-e580"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148866263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
NeoReviewsPub Date : 2026-09-01DOI: 10.1542/neo.27-9-047
Paige Poffenberger, Renee Saggio, Russell Mathews
{"title":"Newborn With Fluid Leakage From Umbilical Stump.","authors":"Paige Poffenberger, Renee Saggio, Russell Mathews","doi":"10.1542/neo.27-9-047","DOIUrl":"https://doi.org/10.1542/neo.27-9-047","url":null,"abstract":"","PeriodicalId":19465,"journal":{"name":"NeoReviews","volume":"27 9","pages":"e585-e588"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148866178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
NeoReviewsPub Date : 2026-09-01DOI: 10.1542/neo.27-9-050
Sheema Gaffar, Molly Crimmins Easterlin
{"title":"Red Blood Cell Transfusion for Preterm and Term Infants in the NICU.","authors":"Sheema Gaffar, Molly Crimmins Easterlin","doi":"10.1542/neo.27-9-050","DOIUrl":"10.1542/neo.27-9-050","url":null,"abstract":"<p><p>Red blood cell (RBC) transfusion practices in neonatal intensive care units are variable. Determining which patients should be transfused, and the specific hemoglobin or hematocrit thresholds, remains a recurring challenge in neonatal intensive care. Although some well-conducted randomized controlled trials and short-term follow-up studies exist for premature infants, data on term infants remain limited. Most information on term infants is derived from heterogeneous observational studies or expert consensus guidelines intended for a wider pediatric critical care population. In this review, we summarize the current literature on RBC transfusions in preterm and term infants, discuss unique characteristics of critically ill infants with varying comorbidities, and provide general strategies to guide the neonatologist in deciding when to transfuse RBCs. We also review specific considerations during RBC transfusion, such as volume, rate, and preparation as well as strategies to decrease the need for RBC transfusions.</p>","PeriodicalId":19465,"journal":{"name":"NeoReviews","volume":"27 9","pages":"e555-e570"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148866186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
NeoReviewsPub Date : 2026-08-01DOI: 10.1542/neo.27-7-041
Akosua Oppong, Michelle J Wang, Ingrid Liff
{"title":"Chickenpox at a Term Gestation: Perinatal Challenges of Primary Varicella Infection.","authors":"Akosua Oppong, Michelle J Wang, Ingrid Liff","doi":"10.1542/neo.27-7-041","DOIUrl":"https://doi.org/10.1542/neo.27-7-041","url":null,"abstract":"","PeriodicalId":19465,"journal":{"name":"NeoReviews","volume":"27 8","pages":"e528-e531"},"PeriodicalIF":0.0,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148648934","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
NeoReviewsPub Date : 2026-08-01DOI: 10.1542/neo.27-7-039
Aneesha Geraghty, Patrick Smith, Kristen Arnold, Paul S Kingma
{"title":"Pulmonary Hypoplasia.","authors":"Aneesha Geraghty, Patrick Smith, Kristen Arnold, Paul S Kingma","doi":"10.1542/neo.27-7-039","DOIUrl":"10.1542/neo.27-7-039","url":null,"abstract":"<p><p>Pulmonary hypoplasia is a rare but clinically significant congenital disorder characterized by impaired fetal lung development, leading to impaired growth and maturation of lung parenchyma and pulmonary vasculature. Stemming from a diverse group of underlying etiologies including congenital diaphragmatic hernia, congenital lung malformations, and prolonged oligohydramnios, the clinical presentation of pulmonary hypoplasia is highly variable. Although many factors affect severity of disease, pulmonary hypoplasia can be life-threatening and accounts for a disproportionately high proportion of neonatal morbidity and mortality. Advances in fetal ultrasonography and fetal magnetic resonance imaging have improved the ability to evaluate the severity of pulmonary hypoplasia before birth and predict clinical outcomes. Prenatal interventions like fetal endoscopic tracheal occlusion or serial amnioinfusions have showed promise in helping alleviate lethal pulmonary hypoplasia, but ongoing research is required to identify techniques that mitigate the associated complications and morbidities. Postnatal management requires multidisciplinary and individualized care, with management tailored toward gentle ventilatory support and surgical management of the underlying cause when applicable. Severe respiratory failure and pulmonary hypertension are hallmarks of severe cases, and extracorporeal membrane oxygenation support is sometimes required. Although advances in care from fetal diagnosis through long-term follow-up have improved survival in some groups, long-term survivors still exhibit persistent impairments in growth, pulmonary function, and neurodevelopment. Infants with pulmonary hypoplasia continue to have high morbidity and mortality, and ongoing research is required to optimize their clinical outcomes.</p>","PeriodicalId":19465,"journal":{"name":"NeoReviews","volume":"27 8","pages":"e511-e522"},"PeriodicalIF":0.0,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148648870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
NeoReviewsPub Date : 2026-08-01DOI: 10.1542/neo.27-7-040
Andrew M Beverstock, Steven M Lazar, Sharada H Gowda, Caraciolo J Fernandes
{"title":"Nemaline Myopathy Associated With Bilateral Chylothorax in a Term Neonate.","authors":"Andrew M Beverstock, Steven M Lazar, Sharada H Gowda, Caraciolo J Fernandes","doi":"10.1542/neo.27-7-040","DOIUrl":"https://doi.org/10.1542/neo.27-7-040","url":null,"abstract":"","PeriodicalId":19465,"journal":{"name":"NeoReviews","volume":"27 8","pages":"e523-e527"},"PeriodicalIF":0.0,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148648898","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}