Obesity SurgeryPub Date : 2024-09-06DOI: 10.1007/s11695-024-07487-9
Kirstie M Herb Neff, G Craig Wood, Christopher D Stil
{"title":"Changes in Internalized Weight Bias and Associations with Weight Loss Outcomes After Bariatric Surgery.","authors":"Kirstie M Herb Neff, G Craig Wood, Christopher D Stil","doi":"10.1007/s11695-024-07487-9","DOIUrl":"https://doi.org/10.1007/s11695-024-07487-9","url":null,"abstract":"","PeriodicalId":19460,"journal":{"name":"Obesity Surgery","volume":null,"pages":null},"PeriodicalIF":2.9,"publicationDate":"2024-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142140688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Obesity SurgeryPub Date : 2024-09-05DOI: 10.1007/s11695-024-07488-8
Marijn T F Jense, Tymen Hodde, Inge H Palm-Meinders, Paul H A Bours, Khalida Soufidi, Evert-Jan G Boerma, Jan Willem M Greve
{"title":"The POSE-2 Procedure for People with Obesity: A Safe and Effective Treatment Option.","authors":"Marijn T F Jense, Tymen Hodde, Inge H Palm-Meinders, Paul H A Bours, Khalida Soufidi, Evert-Jan G Boerma, Jan Willem M Greve","doi":"10.1007/s11695-024-07488-8","DOIUrl":"https://doi.org/10.1007/s11695-024-07488-8","url":null,"abstract":"<p><strong>Purpose: </strong>Besides lifestyle interventions, medication, and surgery, endoscopic options are becoming part of the current treatment landscape for people with obesity. With the POSE (Primary Obesity Surgery Endoscopic) procedure, endoluminal folds are created in the stomach with full-thickness sutures. Recently, the modified version, POSE-2, was introduced in clinical practice. This study aims to evaluate the safety and effectiveness of the POSE-2 procedure after one year in patients with obesity.</p><p><strong>Materials and methods: </strong>All patients treated with the POSE-2 procedure between March 2019 and November 2022 in the Zuyderland Medical Center and the Dutch Obesity Clinic were included in this retrospective data study. Inclusion criteria are as follows: age between 18 and 65 years and a BMI > 30 kg/m<sup>2</sup>. All patients with contraindications for the POSE-2 procedure were excluded.</p><p><strong>Results: </strong>Forty-nine patients were included of which 86% were female, with a mean age of 46 years and mean BMI of 34.6 kg/m<sup>2</sup>. Total weight loss was evaluated at 3, 6, and 12 months and was 11.5%, 13.2%, and 14.8%, respectively. A median of 14 anchor sutures was used in a median procedure time of 50 min. All patients except one had same day discharge. Postprocedural complaints were mild and consisted of nausea and vomiting (36.7%) and pain (54.2%). No complications were recorded in this group. One week postprocedure, most patients (95.9%) reported feeling satisfied between meals.</p><p><strong>Conclusion: </strong>The POSE-2 procedure can be applied as a safe and effective treatment for people with obesity. This study presents a positive effect on weight reduction and no complications after 1 year of follow-up.</p>","PeriodicalId":19460,"journal":{"name":"Obesity Surgery","volume":null,"pages":null},"PeriodicalIF":2.9,"publicationDate":"2024-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142133311","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comparison of Gastric Residual Volume After Ingestion of A Carbohydrate Drink and Water in Healthy Volunteers with Obesity: A Randomized Crossover Study.","authors":"Chanatthee Kitsiripant, Thipok Rujirapat, Sunisa Chatmongkolchart, Jutarat Tanasansuttiporn, Khanin Khanungwanitkul","doi":"10.1007/s11695-024-07493-x","DOIUrl":"https://doi.org/10.1007/s11695-024-07493-x","url":null,"abstract":"<p><strong>Introduction: </strong>Preoperative carbohydrate intake is essential to enhance postoperative recovery. However, its safety for individuals with obesity remains unclear. This study investigated the safety of preoperative carbohydrate consumption compared to water intake in obese populations through gastric volume assessment.</p><p><strong>Methods: </strong>A prospective randomized crossover study enrolled 30 healthy volunteers aged 18-65 years with a body mass index ≥ 30 kg/m<sup>2</sup>, following a minimum 6-h fast. The participants received either 400 ml of a carbohydrate drink (group C) or water (group W). Gastric ultrasonography, blood glucose level, hunger, and thirst assessments were conducted at baseline (T) and various time points (T2 to T6). The protocol was repeated with reverse interventions at least 1 week later.</p><p><strong>Results: </strong>Group C had significantly higher gastric volume at T3, T4, and T5 compared to group W, with a prolonged time to empty the gastric antrum (94.4 ± 28.5 vs. 61.0 ± 33.5 min, 95% CI 33.41 [17.06,24.69]). However, glucose levels, degrees of hunger, and thirst showed no significant differences between the groups.</p><p><strong>Conclusion: </strong>Administering 400 ml of preoperative carbohydrates to healthy obese individuals 2 h preoperatively is safe and comparable to water intake. These findings support the integration of carbohydrate loading into perioperative care for obese individuals, consistent with the enhanced recovery after surgery protocols. Further research is warranted to refine preoperative fasting protocols and improve surgical outcomes in this population.</p>","PeriodicalId":19460,"journal":{"name":"Obesity Surgery","volume":null,"pages":null},"PeriodicalIF":2.9,"publicationDate":"2024-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142133308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Obesity SurgeryPub Date : 2024-09-05DOI: 10.1007/s11695-024-07502-z
Liqi Li
{"title":"ChatGPT vs. Medical Resources for ESG Education Evaluation.","authors":"Liqi Li","doi":"10.1007/s11695-024-07502-z","DOIUrl":"https://doi.org/10.1007/s11695-024-07502-z","url":null,"abstract":"","PeriodicalId":19460,"journal":{"name":"Obesity Surgery","volume":null,"pages":null},"PeriodicalIF":2.9,"publicationDate":"2024-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142133307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Obesity SurgeryPub Date : 2024-09-05DOI: 10.1007/s11695-024-07455-3
Helen Margaret Lawler, Mary Elizabeth Patti, Matthew R Krecic, Jennifer Rowell, Adrian Dobs, Anh Nguyen, Valentina Conoscenti
{"title":"Mini-Dose Ready-to-Use Liquid Glucagon for Post-Bariatric Hypoglycemia Treatment in Experimental and Real-World Settings.","authors":"Helen Margaret Lawler, Mary Elizabeth Patti, Matthew R Krecic, Jennifer Rowell, Adrian Dobs, Anh Nguyen, Valentina Conoscenti","doi":"10.1007/s11695-024-07455-3","DOIUrl":"https://doi.org/10.1007/s11695-024-07455-3","url":null,"abstract":"","PeriodicalId":19460,"journal":{"name":"Obesity Surgery","volume":null,"pages":null},"PeriodicalIF":2.9,"publicationDate":"2024-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142133310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Obesity SurgeryPub Date : 2024-09-05DOI: 10.1007/s11695-024-07492-y
Ahmed W Al-Humadi, Werd Al-Najim, Sinead Bleiel, Carel W le Roux
{"title":"Laxative Properties of Microencapsulated Oleic Acid Delivered to the Distal Small Intestine in Patients with Constipation after Bariatric Surgery or Treatment with Glucagon-Like- Peptide 1 Analogues.","authors":"Ahmed W Al-Humadi, Werd Al-Najim, Sinead Bleiel, Carel W le Roux","doi":"10.1007/s11695-024-07492-y","DOIUrl":"https://doi.org/10.1007/s11695-024-07492-y","url":null,"abstract":"<p><strong>Background: </strong>Constipation is prevalent after bariatric surgery and glucagon-like-peptide 1 (GLP-1) analogues. Increasing fat content in the distal small intestine and colon can enhance colonic peristalsis, potentially alleviating symptoms of constipation.</p><p><strong>Aim: </strong>We investigated whether oleic acid can ameliorate constipation in patients undergoing bariatric surgery or receiving GLP-1 analogues.</p><p><strong>Methodology: </strong>Fourteen adults with chronic constipation according to Rome IV criteria following bariatric surgery or GLP-1 analogues were on stable treatment for constipation for more than 4 weeks. This randomized double-blind crossover trial compared microcapsules containing 21.25 g of oleic acid delivered in the distal small intestine or the stomach. The primary outcome was changed in the number of bowel motions over 24 h. Exploratory endpoints included alterations in straining, diarrhoea, faecal leakage over 24 h and hunger, fullness, nausea and calorie intake for the 3 h after ingesting the microcapsules.</p><p><strong>Findings: </strong>Receiving oleic acid into the distal small intestine increased number of bowel movements per day (2.5 vs 1.1, p = 0.009) and caused softer stool consistency (p = 0.03). 9/14 of the control group passed motions and 13/14 of the intervention group passed motions in 24 h (p = 0.059). No significant differences were observed in straining (p = 0.65), rapid bowel movements (p = 0.08), accidental leakage (p = 0.32), hunger, fullness, nausea or food intake between the groups (all p > 0.05). There were no disparities in safety profile between groups.</p><p><strong>Conclusion: </strong>Microcapsules containing oleic acid delivered to the distal small intestine appear to be a safe and effective relief from chronic constipation in patients undergoing bariatric surgery and/or receiving GLP-1 analogues.</p>","PeriodicalId":19460,"journal":{"name":"Obesity Surgery","volume":null,"pages":null},"PeriodicalIF":2.9,"publicationDate":"2024-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142133309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Obesity SurgeryPub Date : 2024-09-03DOI: 10.1007/s11695-024-07471-3
Laurent Monino, Lancelot Marique, Yannick Deswysen, Maximilien Thoma, Pierre H Deprez, Pierre Goffette, Benoit Navez, Tom G Moreels
{"title":"Endoscopic Management of Biliary and Pancreatic Pathologies in Roux-en-Y Gastric Bypass Patients: Development of a Treatment Algorithm Based on 9-Year Experience.","authors":"Laurent Monino, Lancelot Marique, Yannick Deswysen, Maximilien Thoma, Pierre H Deprez, Pierre Goffette, Benoit Navez, Tom G Moreels","doi":"10.1007/s11695-024-07471-3","DOIUrl":"https://doi.org/10.1007/s11695-024-07471-3","url":null,"abstract":"<p><strong>Background: </strong>Management of biliopancreatic pathology in Roux-en-Y gastric bypass (RYGB) patients is challenging despite the availability of multiple approaches like single-balloon enteroscopy-assisted ERCP (SBE-ERCP), laparoscopy-assisted ERCP (LA-ERCP), and EUS-directed transgastric intervention (EDGI). We evaluated the outcomes of the interchangeable combination of endoscopic procedures to treat biliopancreatic pathology in RYGB patients.</p><p><strong>Materials and methods: </strong>This is a monocentric retrospective study of consecutive RYGB patients with biliopancreatic pathology between June 2014 and September 2023. Primary endpoints were technical success, adverse events (AE), and parameters of endoscopic procedures according to etiology. A clinically useful management algorithm was developed.</p><p><strong>Results: </strong>A total of 102 patients with RYGB (73 women; mean age 55 ± 10 years) were included. A total of 113 SBE-ERCP (in 90 patients), 26 EDGI (in 23 patients), and 2 LA-ERCP (in 2 patients) were performed. Technical success of SBE-ERCP was lower compared to EDGI (74.4% vs 95.1%, p = 0.002). The AE rate was lower using SBE-ERCP compared to EDGI (12.4% vs 38.5%, p = 0.003). Two sub-groups based on etiology were identified as \"common bile duct stone\" (CBDS) and \"Other.\" In the CBDS group, the mean number and time of procedures were lower in SBE-ERCP as the first-line technique compared to first-line EDGI (1.1 vs 2.7, p < 0.00 and 91 ± 20.7 min vs 161 ± 61.3 min, p < 0.00).</p><p><strong>Conclusion: </strong>A combination of endoscopic procedures can achieve high technical success in managing biliopancreatic pathology in RYGB patients with an acceptable AE rate. In the case of CBDS, SBE-ERCP appeared to be a good first-line single-step option. For other indications, EDGI should be proposed as the first line.</p>","PeriodicalId":19460,"journal":{"name":"Obesity Surgery","volume":null,"pages":null},"PeriodicalIF":2.9,"publicationDate":"2024-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142120275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Obesity SurgeryPub Date : 2024-09-02DOI: 10.1007/s11695-024-07473-1
Tannaz Jamialahamdi, Elaheh Mirhadi, Wael Almahmeed, Vasily N Sukhorukov, Ali H Eid, Sepideh Salehabadi, Amirhossein Sahebkar
{"title":"The Effect of Bariatric Surgery on PAI-1 Levels: A Systematic Review and Meta-analysis.","authors":"Tannaz Jamialahamdi, Elaheh Mirhadi, Wael Almahmeed, Vasily N Sukhorukov, Ali H Eid, Sepideh Salehabadi, Amirhossein Sahebkar","doi":"10.1007/s11695-024-07473-1","DOIUrl":"https://doi.org/10.1007/s11695-024-07473-1","url":null,"abstract":"<p><p>The purpose of this meta-analysis was to determine the effect of bariatric surgery on circulating PAI-1. The meta-analysis was provided by comprehensive meta-analysis (CMA) V4 software. Meta-analysis of 33 studies showed a significant decrease in circulating PAI-1 after bariatric surgery (p < 0.001). A significant reduction was observed for two types of surgery) (p < 0.001 for LSG and p < 0.001 for RYGB). Furthermore, there was a significant change in circulating PAI-1 based on the follow-up duration (p < 0.001 for follow-up < 12 months and p < 0.001 for follow-up ≥ 12). We showed that bariatric surgery changed PAI-1 level significantly and changes in BMI after surgery were not related to PAI-1 alteration. Furthermore, this result was consistent based on follow-up duration and type of surgery.</p>","PeriodicalId":19460,"journal":{"name":"Obesity Surgery","volume":null,"pages":null},"PeriodicalIF":2.9,"publicationDate":"2024-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142110080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Obesity SurgeryPub Date : 2024-09-01Epub Date: 2024-08-06DOI: 10.1007/s11695-024-07357-4
Gregory D Fritz, Aryana Sharrak, Jason Aubrey, Xhesika Topalli, Antonia Vrana, Anne Opalikihn, Giuseppe M Zambito, Thomas D Martin, James A Foote, Joshua R Smith, Jon L Schram
{"title":"Perioperative Outcomes Using Single-Fire Stapler.","authors":"Gregory D Fritz, Aryana Sharrak, Jason Aubrey, Xhesika Topalli, Antonia Vrana, Anne Opalikihn, Giuseppe M Zambito, Thomas D Martin, James A Foote, Joshua R Smith, Jon L Schram","doi":"10.1007/s11695-024-07357-4","DOIUrl":"10.1007/s11695-024-07357-4","url":null,"abstract":"<p><strong>Background: </strong>Laparoscopic sleeve gastrectomy (LSG) is the most common bariatric surgery performed worldwide. The Titan stapler aims to standardize the sleeve gastrectomy by eliminating inconsistencies and simplifying the procedure.</p><p><strong>Methods: </strong>A retrospective chart review was performed on all patients > 18 years of age undergoing LSG using the Titan. Pre-operative demographics, perioperative findings, and post-operative complications were all abstracted from the MBSAQIP database.</p><p><strong>Results: </strong>A total of 807 LSG have been performed using the latest iteration of the Titan stapler since November 2022. Data from these patients was compared to 3829 patients who underwent LSG using a sequential staple firing technique from September 2016-September 2021. The median age of Titan patients was 42 years (IQR 33-52) compared to 44 years (IQR 35-54) for sequential firing. The median pre-operative BMI was 47.1 (IQR 43.5-52.1) for Titan versus 47.6 (IQR 43.1-53.3) for sequential staple firing. After propensity matching, operative duration was significantly less for the Titan. Titan patients had decreased hospital length of stay, experienced fewer 30-day readmissions, and had less post-operative nausea/vomiting. Post-op bleed rates were similar between the two cohorts. Weight loss at 6 months favored the sequential fire arm, but our preliminary data shows this difference diminishes at 1 year.</p><p><strong>Conclusions: </strong>Here we report our data on patients undergoing LSG using the latest Titan stapler. We show the device is safe, effective, and has resulted in an improvement in length of stay, readmissions, and post-operative nausea/vomiting. We also noted reduced operative time with this technique.</p>","PeriodicalId":19460,"journal":{"name":"Obesity Surgery","volume":null,"pages":null},"PeriodicalIF":2.9,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11349793/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141894008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}