Ines Ari, Jacques Himpens, Patricia Loi, Tiana Duray, Marie Barea, Jean Closset
{"title":"比利时某学术中心腹腔镜袖式胃切除术的远期疗效（9年随访）。","authors":"Ines Ari, Jacques Himpens, Patricia Loi, Tiana Duray, Marie Barea, Jean Closset","doi":"10.1007/s11695-025-08301-w","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Laparoscopic sleeve gastrectomy (LSG) is a widely used metabolic-bariatric surgical (MBS) technique, but long-term outcome data remain limited. This study aims to assess the 9-year progression of weight and related comorbidities following LSG.</p><p><strong>Methods: </strong>This retrospective study analyzed data from patients who underwent LSG in 2014, with consent to share data. Participants also completed an \"ad hoc\" questionnaire. Medical data and responses were analyzed using descriptive and inferential statistics.</p><p><strong>Results: </strong>Of the 96 patients, 56 (23/33 males/females) agreed to participate in the follow-up (66.7%) and were assessed. The average initial weight was 119.7 ± 17.3 kg with a median of 117.0 kg (average BMI was 41.1 ± 3.48 kg/m<sup>2</sup> - median 40.5 kg/m<sup>2</sup>). Preoperatively, comorbidities included arterial hypertension (AHT) in 44.6%, dyslipidemia (DL) in 46.4%, sleep apnea syndrome (SAS) in 33.9%, type 2 diabetes (T2DM) in 21.4%, and gastroesophageal reflux disease (GERD) in 53.6% of participants. Nadir BMI was assessed at year 3 (Y3) at a value of 28.2 ± 3.8 kg/m<sup>2</sup>, corresponding to a 31.1 ± 8.8% total weight loss (TWL) - median 30.9%. Weight regains occurred post-Y3, with %TWL of 27.3 ± 9.4% at Y6 and 26.4 ± 10.3% at Y9. The regain between Y3-Y6, Y3-Y9 and Y6-Y9 is considered as being significant; excess weight loss (EWL) at Y9 was 68.0 ± 25.8%. All comorbidities improved, but GERD significantly increased to 75.0% at Y9 (p = 0.0110). Emotional eating significantly impacted weight loss (p = 0.03829).</p><p><strong>Conclusions: </strong>LSG leads to significant long-term weight loss, although some weight regains starting at 3 years postoperatively. LSG also demonstrates lasting benefits for AHT, DL, SAS, and T2DM. However, GERD worsened overtime.</p>","PeriodicalId":19460,"journal":{"name":"Obesity Surgery","volume":" ","pages":""},"PeriodicalIF":3.1000,"publicationDate":"2025-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Long Term Outcomes of Laparoscopic Sleeve Gastrectomy in an Academic Center in Belgium (9 Years Follow-Up).\",\"authors\":\"Ines Ari, Jacques Himpens, Patricia Loi, Tiana Duray, Marie Barea, Jean Closset\",\"doi\":\"10.1007/s11695-025-08301-w\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Laparoscopic sleeve gastrectomy (LSG) is a widely used metabolic-bariatric surgical (MBS) technique, but long-term outcome data remain limited. This study aims to assess the 9-year progression of weight and related comorbidities following LSG.</p><p><strong>Methods: </strong>This retrospective study analyzed data from patients who underwent LSG in 2014, with consent to share data. Participants also completed an \\\"ad hoc\\\" questionnaire. Medical data and responses were analyzed using descriptive and inferential statistics.</p><p><strong>Results: </strong>Of the 96 patients, 56 (23/33 males/females) agreed to participate in the follow-up (66.7%) and were assessed. The average initial weight was 119.7 ± 17.3 kg with a median of 117.0 kg (average BMI was 41.1 ± 3.48 kg/m<sup>2</sup> - median 40.5 kg/m<sup>2</sup>). Preoperatively, comorbidities included arterial hypertension (AHT) in 44.6%, dyslipidemia (DL) in 46.4%, sleep apnea syndrome (SAS) in 33.9%, type 2 diabetes (T2DM) in 21.4%, and gastroesophageal reflux disease (GERD) in 53.6% of participants. Nadir BMI was assessed at year 3 (Y3) at a value of 28.2 ± 3.8 kg/m<sup>2</sup>, corresponding to a 31.1 ± 8.8% total weight loss (TWL) - median 30.9%. Weight regains occurred post-Y3, with %TWL of 27.3 ± 9.4% at Y6 and 26.4 ± 10.3% at Y9. The regain between Y3-Y6, Y3-Y9 and Y6-Y9 is considered as being significant; excess weight loss (EWL) at Y9 was 68.0 ± 25.8%. All comorbidities improved, but GERD significantly increased to 75.0% at Y9 (p = 0.0110). Emotional eating significantly impacted weight loss (p = 0.03829).</p><p><strong>Conclusions: </strong>LSG leads to significant long-term weight loss, although some weight regains starting at 3 years postoperatively. LSG also demonstrates lasting benefits for AHT, DL, SAS, and T2DM. However, GERD worsened overtime.</p>\",\"PeriodicalId\":19460,\"journal\":{\"name\":\"Obesity Surgery\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":3.1000,\"publicationDate\":\"2025-10-16\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Obesity Surgery\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1007/s11695-025-08301-w\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"SURGERY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Obesity Surgery","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s11695-025-08301-w","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"SURGERY","Score":null,"Total":0}
Long Term Outcomes of Laparoscopic Sleeve Gastrectomy in an Academic Center in Belgium (9 Years Follow-Up).
Background: Laparoscopic sleeve gastrectomy (LSG) is a widely used metabolic-bariatric surgical (MBS) technique, but long-term outcome data remain limited. This study aims to assess the 9-year progression of weight and related comorbidities following LSG.
Methods: This retrospective study analyzed data from patients who underwent LSG in 2014, with consent to share data. Participants also completed an "ad hoc" questionnaire. Medical data and responses were analyzed using descriptive and inferential statistics.
Results: Of the 96 patients, 56 (23/33 males/females) agreed to participate in the follow-up (66.7%) and were assessed. The average initial weight was 119.7 ± 17.3 kg with a median of 117.0 kg (average BMI was 41.1 ± 3.48 kg/m2 - median 40.5 kg/m2). Preoperatively, comorbidities included arterial hypertension (AHT) in 44.6%, dyslipidemia (DL) in 46.4%, sleep apnea syndrome (SAS) in 33.9%, type 2 diabetes (T2DM) in 21.4%, and gastroesophageal reflux disease (GERD) in 53.6% of participants. Nadir BMI was assessed at year 3 (Y3) at a value of 28.2 ± 3.8 kg/m2, corresponding to a 31.1 ± 8.8% total weight loss (TWL) - median 30.9%. Weight regains occurred post-Y3, with %TWL of 27.3 ± 9.4% at Y6 and 26.4 ± 10.3% at Y9. The regain between Y3-Y6, Y3-Y9 and Y6-Y9 is considered as being significant; excess weight loss (EWL) at Y9 was 68.0 ± 25.8%. All comorbidities improved, but GERD significantly increased to 75.0% at Y9 (p = 0.0110). Emotional eating significantly impacted weight loss (p = 0.03829).
Conclusions: LSG leads to significant long-term weight loss, although some weight regains starting at 3 years postoperatively. LSG also demonstrates lasting benefits for AHT, DL, SAS, and T2DM. However, GERD worsened overtime.
期刊介绍：
Obesity Surgery is the official journal of the International Federation for the Surgery of Obesity and metabolic disorders (IFSO). A journal for bariatric/metabolic surgeons, Obesity Surgery provides an international, interdisciplinary forum for communicating the latest research, surgical and laparoscopic techniques, for treatment of massive obesity and metabolic disorders. Topics covered include original research, clinical reports, current status, guidelines, historical notes, invited commentaries, letters to the editor, medicolegal issues, meeting abstracts, modern surgery/technical innovations, new concepts, reviews, scholarly presentations and opinions.
Obesity Surgery benefits surgeons performing obesity/metabolic surgery, general surgeons and surgical residents, endoscopists, anesthetists, support staff, nurses, dietitians, psychiatrists, psychologists, plastic surgeons, internists including endocrinologists and diabetologists, nutritional scientists, and those dealing with eating disorders.
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