Obesity Science & Practice最新文献

{"title":"The individual-level effects of social media campaigns related to healthy eating, physical activity, and healthy weight: A narrative review.","authors":"Yajing Luo, Ana G Maafs-Rodríguez, Daniel P Hatfield","doi":"10.1002/osp4.731","DOIUrl":"10.1002/osp4.731","url":null,"abstract":"<p><strong>Objective: </strong>Social media are promising channels for health communication promoting positive weight-related behaviors, but no prior studies have synthesized evidence on the independent effects of social media campaigns focused on promoting healthy eating, physical activity (PA), and healthy weight. This study aimed to fill that gap and inform future social media-based obesity-prevention research and practice by reviewing findings from studies testing the effects of such campaigns on individual-level cognitive, behavioral, and anthropometric outcomes.</p><p><strong>Method: </strong>The Web of Science and PubMed databases were searched for peer-reviewed articles published between 2012 and 2023 that explored the independent effects of social media campaigns related to healthy eating, PA, or weight management. Study characteristics and outcomes were extracted and summarized.</p><p><strong>Results: </strong>Eleven studies were included in this review describing campaigns targeting healthy eating-related outcomes (e.g., fruit and vegetable consumption, meal preparation, nutrition label reading), PA, or weight management. Most campaigns (<i>n</i> = 7) were developed by universities or research centers. Priority audiences included parents, adult females, adolescents, college students, and adult government employees. The majority (<i>n</i> = 8) of the campaigns used single platforms, with the most common being Facebook, Instagram, blogs, and YouTube. Campaigns had mixed effects on cognitive outcomes (e.g., intention, attitude, knowledge), behavioral outcomes (e.g., food choices, PA), and anthropometric outcomes (e.g., weight, waist circumference).</p><p><strong>Conclusion: </strong>Social media campaigns focused on promoting healthy eating, PA, and healthy weight had mixed effects on individual-level cognitive, behavioral, and anthropometric outcomes. Various limitations of the included studies make it difficult to ascertain which factors influence campaign effectiveness. Advancing knowledge in this area is important, particularly given social media's widespread use and potential for broad reach. New research with features such as rigorous study designs, larger and more diverse samples, and strong theoretical foundations may provide important insights into what types of interventions are effective or not and under what conditions.</p>","PeriodicalId":19448,"journal":{"name":"Obesity Science & Practice","volume":"10 1","pages":"e731"},"PeriodicalIF":1.9,"publicationDate":"2024-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10767147/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139378026","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Continuous glucose monitoring captures glycemic variability in obesity after sleeve gastrectomy: A prospective cohort study.","authors":"Brenda Dorcely, Julie DeBermont, Akash Gujral, Migdalia Reid, Sally M Vanegas, Collin J Popp, Michael Verano, Melanie Jay, Ann Marie Schmidt, Michael Bergman, Ira J Goldberg, José O Alemán","doi":"10.1002/osp4.729","DOIUrl":"10.1002/osp4.729","url":null,"abstract":"<p><strong>Objective: </strong>HbA1c is an insensitive marker for assessing real-time dysglycemia in obesity. This study investigated whether 1-h plasma glucose level (1-h PG) ≥155 mg/dL (8.6 mmol/L) during an oral glucose tolerance test (OGTT) and continuous glucose monitoring (CGM) measurement of glucose variability (GV) better reflected dysglycemia than HbA1c after weight loss from metabolic and bariatric surgery.</p><p><strong>Methods: </strong>This was a prospective cohort study of 10 participants with type 2 diabetes compared with 11 participants with non-diabetes undergoing sleeve gastrectomy (SG). At each research visit; before SG, and 6 weeks and 6 months post-SG, body weight, fasting lipid levels, and PG and insulin concentrations during an OGTT were analyzed. Mean amplitude of glycemic excursions (MAGE), a CGM-derived GV index, was analyzed.</p><p><strong>Results: </strong>The 1-h PG correlated with insulin resistance markers, triglyceride/HDL ratio and triglyceride glucose index in both groups before surgery. At 6 months, SG caused 22% weight loss in both groups. Despite a reduction in HbA1c by 3.0 ± 1.3% in the diabetes group (<i>p</i> < 0.01), 1-h PG, and MAGE remained elevated, and the oral disposition index, which represents pancreatic <i>β</i>-cell function, remained reduced in the diabetes group when compared to the non-diabetes group.</p><p><strong>Conclusions: </strong>Elevation of GV markers and reduced disposition index following SG-induced weight loss in the diabetes group underscores persistent <i>β</i>-cell dysfunction and the potential residual risk of diabetes complications.</p>","PeriodicalId":19448,"journal":{"name":"Obesity Science & Practice","volume":"10 1","pages":"e729"},"PeriodicalIF":1.9,"publicationDate":"2024-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10768733/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139378024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Long term cost outcomes among commercially insured patients undergoing bariatric surgical procedures.","authors":"Sonali Shambhu, Qinli Ma, Aliza S Gordon, David Pryor, Joseph A Karam, Andrea DeVries","doi":"10.1002/osp4.727","DOIUrl":"10.1002/osp4.727","url":null,"abstract":"<p><strong>Objective: </strong>Bariatric procedures have become safer in recent years, warranting new data on long-term costs. This study examined the impact of bariatric procedures on a person's long-term healthcare costs up to 10 years and if it differed by socio-economic status (SES).</p><p><strong>Methods: </strong>This retrospective observational study compared the downstream health care cost of patients with obesity who had undergone bariatric surgery (BS) between 2009 and 2018 to a 1:1 matched group of members with obesity but no surgery.</p><p><strong>Results: </strong>167,764 individuals from administrative claims data with an obesity diagnosis were included; 83,882 in the BS group and 83,882 in the non-surgical group. In follow-up years 2-10, the BS group was associated with lower total medical healthcare cost compared to the non-surgical group (cost ratios ranged 0.85-0.93, <i>p</i> values < 0.05). When stratifying the BS group by SES quartiles, there were no significant cost differences by SES (cost ratios ranged from 0.96 to 1.05, most <i>p</i> values > 0.05).</p><p><strong>Conclusions: </strong>BS was associated with lower long-term follow-up medical cost and cost savings appeared similar among the SES quartiles in the BS group. The study results may help policy makers and employers in designing benefits and extending coverage for bariatric surgical procedures.</p>","PeriodicalId":19448,"journal":{"name":"Obesity Science & Practice","volume":"10 1","pages":"e727"},"PeriodicalIF":1.9,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10766043/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139378025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Associations of daily weight management‐focused social support with weight loss, activity behaviors, and eating regulation in the context of metabolic and bariatric surgery","authors":"Dale S. Bond, Kathryn E. Smith, Leah M. Schumacher, Sivamainthan Vithiananthan, Daniel B. Jones, Pavlos Papasavas, Jennifer Webster, J. Graham Thomas","doi":"10.1002/osp4.717","DOIUrl":"https://doi.org/10.1002/osp4.717","url":null,"abstract":"Abstract Objective Greater perceived social support (PSS) is associated with more favorable changes in weight loss, activity behaviors, and eating regulation after metabolic and bariatric surgery (MBS). However, studies have relied on generic, retrospective PSS measures, and stability of PSS levels and relations with weight loss and weight‐related behaviors over time is unknown. Using smartphone‐based Ecological Momentary Assessment, this study evaluated pre‐to 1‐year post‐MBS changes in daily weight management‐focused PSS and associations with weight loss, device‐measured activity behaviors, and eating regulation before and during the initial year after MBS. Method Adult MBS patients ( n = 71) received (1) an accelerometer to measure daily moderate‐to‐vigorous intensity physical activity (MVPA) and sedentary time (ST) minutes/day, and (2) a smartphone to complete morning weight‐focused PSS ratings and eating regulation (dietary restraint/disinhibition) ratings at four semi‐random times daily for 10 days at pre‐ and 3, 6, and 12‐month postoperative. Generalized linear mixed models analyzed the associations of PSS with total weight loss (%TWL) and activity/eating outcomes. Results Participants on average reported relatively stable moderate‐to‐high PSS (3.98 on one to five scale) across assessments. Perceived social support was not related to %TWL, MVPA, or ST. Participants with higher PSS reported lower disinhibition and higher restraint than those with lower PSS (ps < 0.05); however, participants reported higher restraint on days that PSS was lower than their usual levels ( p = 0.009). Conclusions MBS patients on average had stable PSS levels across time. Higher PSS levels were associated with greater resistance to overeating cues (disinhibition) and cognitive control to restrict food intake (restraint) over time. Additionally, participants reported higher restraint when PSS levels were lower than usual. Overall, weight‐focused PSS appeared to hold greater importance in relation to regulating eating behavior than engaging in activity behaviors or weight loss among MBS patients during the initial postoperative year. Clinical Trial Registration NCT02777177.","PeriodicalId":19448,"journal":{"name":"Obesity Science & Practice","volume":"74 4","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135088363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A comparison of virtual and in person delivery of a full meal replacement program for obesity","authors":"Matthew Skeldon, David Harris, Robert Dent, Judy Y Shiau","doi":"10.1002/osp4.718","DOIUrl":"https://doi.org/10.1002/osp4.718","url":null,"abstract":"Abstract Objective Full meal replacement (FMR) Intensive Lifestyle Interventions (ILI) have been used for weight management. However, predictors of efficacy with these programs are less clear. The primary objective was to assess weight loss predictors in a community‐based FMR ILI program. A secondary objective was to determine if weight loss was different between virtual and in person ILI. Methods This was a retrospective cohort study involving 234 patients who started the program between 1 January 2016 and 3 March 2021. In the 24‐week program, patients spent 12 weeks on FMR and then transitioned back to food for the remainder, with weekly follow up with a physician and group sessions with a dietitian. Visits were in person prior to March 2020 and virtual afterward. Results Patients' average age was 47.5 years (SD = 12.0) and 73.5% were female. Average weight loss was 14.3% (SD = 6.2%). There was no significant difference in weight loss between virtual and in person programs. Patients on a Glucagon‐like Peptide‐1 Receptor Agonist prior lost less weight. Other significant associations between groups were baseline Hemoglobin A 1 C, classes attended, as well as the age since peak weight. Conclusion Weight loss from virtual ILI was not significantly different from person ILI. More research is needed to determine how to best stratify care as virtual or in person using FMR programs.","PeriodicalId":19448,"journal":{"name":"Obesity Science & Practice","volume":"34 4","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135769513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Patient perspectives about treatment preferences for obesity with complications","authors":"Craig HC, Alsaeed D, Norris S, Holian J, Kennedy C, Feldman A, CW le Roux","doi":"10.1002/osp4.720","DOIUrl":"https://doi.org/10.1002/osp4.720","url":null,"abstract":"Abstract Objective Obesity and many of its comorbidities can be improved by nutritional therapy, lifestyle modification, pharmacotherapy, and surgical intervention. Relatively little is known about patients' preferences for the range of obesity treatments. The present study was undertaken to identify factors that may influence these preferences. By evaluating patient‐preferred treatment options and factors influencing patients, treatment adherence and efficacy may be improved. Our objective was to identify factors that influence patient preferences and subsequent choice of obesity treatment among those seeking treatment for obesity‐related complications. Methods Participatory action research, using purposeful sampling, was used to recruit 33 patients with obesity complications. Recruitment took place in specialist clinics for non‐alcoholic fatty liver disease, diabetes, hypertension, and chronic kidney disease. Sixteen males and 17 females aged 18–70 years with a BMI&gt;35 kg/m 2 were recruited. Prior to the interview, participants watched a 60‐min video explaining nutritional therapies, pharmacotherapies, and surgical therapies in equipoise. Data were collected in one‐to‐one semi‐structured interviews using zoom or the telephone; reflective thematic analysis was used. Results Four themes emerged: 1) structural factors, 2) autonomy, 3) interaction with formal care, and 4) the emotional and physical consequences of obesity. 39% of participants preferred nutritional therapy with support from medical professionals. 27% chose bariatric surgery. 24% chose pharmacotherapy alone, while 6% chose pharmacotherapy combined with nutritional therapy, 3% of participants wanted no intervention. Conclusion The challenges can be addressed by increasing support for healthcare professionals toward enhancing both their knowledge and the health literacy of patients. Future research should focus on improving access to treatment pathways for patients as well as developing health literacy programs and educational programs for healthcare professionals.","PeriodicalId":19448,"journal":{"name":"Obesity Science & Practice","volume":"63 9","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136134075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A qualitative study of perceived barriers and facilitators to interrupting sedentary behaviour among adults living with obesity","authors":"Fiona Curran, Carol Brennan, James Matthews, Grainne O’ Donoghue","doi":"10.1002/osp4.721","DOIUrl":"https://doi.org/10.1002/osp4.721","url":null,"abstract":"Abstract Introduction Both obesity and sedentary behaviour (SB), are associated with negative health consequences including cardiovascular disease, diabetes, certain cancers and all‐cause mortality. To date, perceived barriers and facilitators to interrupting SB in adults living with obesity have not been identified. Objective This study aimed to identify these perceived barriers and facilitators by conducting a behavioural analysis underpinned by the theoretical domains framework (TDF) and the Capability, Opportunity, Motivation‐Behaviour (COM‐B) model, to enhance knowledge and inform future intervention development. Methods A purposive and snowball sample (N=21) of adults living with obesity took part in semi‐structured interviews, guided by the TDF, to investigate perceived barriers or facilitators to interrupting SB. Transcribed interviews were inductively coded using reflexive thematic analysis. Key themes and subthemes were generated by grouping similar and recurring codes. Finally, subthemes were mapped to the TDF and COM‐B. Results Five key themes were identified, which influence SB across all domains of living. These relate to (i) physical and mental wellbeing; (ii) motivational readiness; (iii) roles, responsibilities and support; (iv) weight bias and stigma and (v) the environment. These themes were then deductively mapped to all 14 TDF domains and all six of the COM‐B constructs. Conclusion A complex interplay of individual, societal and policy factors contribute to the development and habituation of SB patterns for adults living with obesity. Factors identified in this study could assist in the development of interventions, strategies and policies designed to interrupt or reduce sedentary behaviour for this population. This article is protected by copyright. All rights reserved.","PeriodicalId":19448,"journal":{"name":"Obesity Science & Practice","volume":"9 2","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136312049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"“Psychological well‐being as a motive for and result of post‐bariatric body contouring procedures”","authors":"Authors Britta Pehlke, Filipa Oliveira, Charalampos Varnava, Fabian Nehls, Philipp Wiebringhaus, Maximilian Kueckelhaus, Tobias Hirsch, Alexander Frederik Dermietzel","doi":"10.1002/osp4.719","DOIUrl":"https://doi.org/10.1002/osp4.719","url":null,"abstract":"Abstract Objective This study investigates whether psychological well‐being in post‐bariatric patients seeking body contouring procedures differ from those who do not seek body contouring procedures, those who have already undergone body contouring procedures, and those who are unsure about body contouring procedures. Methods An anonymous, nonrandomized, cross‐sectional survey study was designed. Psychological well‐being of four groups of post‐bariatric‐patients (undergone body contouring procedures, seeking body contouring procedures, not seeking body contouring procedures, unsure about body contouring procedures) was compared. Results A total of 345 patients were included in this study. No significant difference between patients seeking body contouring procedures and those not seeking body contouring procedures was found with regard to depressive symptoms, self‐esteem, and body image. Patients who had already undergone body contouring procedures scored lower on depressive symptoms (p=.035), and reported to feel more attractive (p<.001) and less insecure (p=.030) than patients who had not undergone body contouring procedures yet but seeked it. Satisfaction with the result of the body contouring procedures was associated with lower depression levels (p<.001), higher self‐esteem (p<.001) and a more positive body‐image (p<.001). Conclusions Depressive symptoms or a low self‐esteem are not motivational factors for post‐bariatric patients to seek body contouring procedures. body contouring procedures is, however, associated with improvement in psychological well‐being in post‐bariatric patients. The patients’ satisfaction with the result of the body contouring procedures is significantly associated with positive psychological well‐being. This article is protected by copyright. All rights reserved.","PeriodicalId":19448,"journal":{"name":"Obesity Science & Practice","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135617667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adipose triglyceride lipase gene expression in peripheral blood mononuclear cells of subjects with obesity and its association with insulin resistance, inflammation and lipid accumulation in liver","authors":"Samira Ezzati‐Mobaser, Sahar Yarahmadi, Nikta Dadkhah Nikroo, Mohammad Hasan Maleki, Zeynab Yousefi, Pegah Golpour, Mona Nourbakhsh, Mitra Nourbakhsh","doi":"10.1002/osp4.716","DOIUrl":"https://doi.org/10.1002/osp4.716","url":null,"abstract":"Abstract Introduction Adipose triglyceride lipase (ATGL) is a crucial enzyme responsible for the release of fatty acids from various tissues. The expression of ATGL is regulated by insulin and this enzyme is linked to insulin resistance. On the other hand, ATGL‐mediated lipolysis is connected to macrophage function and thus ATGL is involved in inflammation and the pathogenesis of lipid‐related disorders. This study aims to investigate the correlation between ATGL, obesity, metabolic syndrome, and inflammation. Methods A total of 100 participants, including 50 individuals with obesity and 50 healthy particiapnts, were recruited for this study and underwent comprehensive clinical evaluations. Blood samples were collected to measure plasma lipid profiles, glycemic indices, and liver function tests. Additionally, peripheral blood mononuclear cells (PBMCs) were isolated and used for the assessment of the gene expression of ATGL, using real‐time PCR. Furthermore, PBMCs were cultured and exposed to lipopolysaccharides (LPS) with simultaneous ATGL inhibition, and the gene expression of inflammatory cytokines, along with the secretion of prostaglandin E2 (PGE2), were measured. Results The gene expression of ATGL was significantly elevated in PBMCs obtained from participants with obesity and was particularly higher in those diagnosed with metabolic syndrome. It exhibited a correlation with insulin levels and Homeostatic Model Assessment for Insulin Resistance (HOMA‐IR), and it was associated with lipid accumulation in the liver. Stimulation with LPS increased ATGL expression in PBMCs, while inhibition of ATGL attenuated the inflammatory responses induced by LPS. Conclusions Obesity and metabolic syndrome were associated with dysregulation of ATGL. ATGL might play a role in the upregulation of inflammatory cytokines and act as a significant contributor to the development of metabolic abnormalities related to obesity. This article is protected by copyright. All rights reserved.","PeriodicalId":19448,"journal":{"name":"Obesity Science & Practice","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136185516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lipid Accumulation Product and Visceral Adiposity Index for Incidence of Cardiovascular Diseases and Mortality; Results From 13 Years Follow‐up in Isfahan Cohort Study","authors":"Mohammad Fakhrolmobasheri, Amir Parsa Abhari, Maryam Heidarpour, Saina Paymannejad, Mahsa Pourmahdi‐Boroujeni, Amir Sepehr Saffari, Paria Okhovat, Hamidreza Roohafza, Masoumeh Sadeghi, Najmeh Rabanipour, Davood Shafie, Nizal Sarrafzadehgan","doi":"10.1002/osp4.713","DOIUrl":"https://doi.org/10.1002/osp4.713","url":null,"abstract":"Abstract Background /Aims: Visceral adiposity index (VAI) and lipid accumulation product (LAP) are novel anthropometric indices that have shown an association with metabolic syndrome; however, limited data are available regarding the predictive performance of these indices for the incidence of cardiovascular diseases (CVD) and mortality. Methods This study was performed on the data retrieved from Isfahan Cohort Study (ICS). ICS is an ongoing population‐based cohort study conducted in 3 counties in central Iran. Pearson correlation analysis was performed between LAP, VAI, and metabolic parameters. Cox regression analysis and receiver operative characteristics (ROC) curve analysis were performed in order to evaluate the ability of VAI and LAP for the incidence of CVD, CVD‐associated mortality, and all‐cause mortality. We further compared the predictive performance of VAI and LAP with body mass index (BMI). Results LAP and VAI were significantly correlated with all metabolic variables, including blood pressure, fasting blood glucose, and lipid profile components. Univariate regression analysis indicated a significant association between LAP and VAI and CVD incidence. In multivariate analysis, only VAI was significantly associated with CVD incidence. Regarding CVD mortality, only VAI in the multivariate analysis revealed a significant association. Interestingly, Both VAI and LAP were negatively associated with all‐cause mortality. ROC curve analysis indicated the superior performance of LAP and VAI for predicting CVD incidence compared to BMI; however, BMI was better in predicting all‐cause mortality. Conclusion Compared to BMI, LAP and VAI have better predictive performance for the incidence of CVD. In contrast, BMI was superior to VAI and LAP in the prediction of all‐cause mortality.","PeriodicalId":19448,"journal":{"name":"Obesity Science & Practice","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135790227","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}