Obesity Science & Practice最新文献

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Home access to a weight scale in the Hispanic/Latino population attending a community‐based free clinic 参加社区免费诊所的西班牙裔/拉丁裔人群的家庭体重秤
Obesity Science & Practice Pub Date : 2023-09-30 DOI: 10.1002/osp4.711
Ken Fujioka, Jacob Fujioka, Kaley Mafong, Nicole Wetherhold, Sally Kim, Amin Rasul, Alyssa Lopez, Kevin Cummins
{"title":"Home access to a weight scale in the Hispanic/Latino population attending a community‐based free clinic","authors":"Ken Fujioka, Jacob Fujioka, Kaley Mafong, Nicole Wetherhold, Sally Kim, Amin Rasul, Alyssa Lopez, Kevin Cummins","doi":"10.1002/osp4.711","DOIUrl":"https://doi.org/10.1002/osp4.711","url":null,"abstract":"Abstract Background Daily weighing has been shown to help with weight management. In primary care, the majority of virtual visits will ask patients about their weight. However, little is known about whether patients, especially those in the Hispanic/Latino population, have access to a weight scale. Our aim was to determine scale access and perceived height and weight in the Hispanic/Latino population attending a volunteer, no cost, community clinic. Methods Questionnaires were issued to patients attending the community clinic and a comparator group attending a medically insured primary care practice. Results Only 52% of the Hispanic/Latino patients attending the community clinic had access to a scale compared with 85% of patients in the primary care office. Patients underreported weight and overreported height leading to underreporting body mass index by 0.6 ± 3.2 kg/m 2 . Conclusions Healthcare providers who care for uninsured Hispanic/Latino patients in community clinics may need to be aware that patients may not have access to a scale.","PeriodicalId":19448,"journal":{"name":"Obesity Science & Practice","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136277029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of overweight/obesity and metabolic syndrome on frailty in middle‐aged and older Japanese adults 超重/肥胖和代谢综合征对日本中老年成年人虚弱的影响
Obesity Science & Practice Pub Date : 2023-09-27 DOI: 10.1002/osp4.714
Yuki Nishida, Yosuke Yamada, Satoshi Sasaki, Eiichiro Kanda, Yoshihiko Kanno, Tatsuhiko Anzai, Kunihiko Takahashi, Keita Yamauchi, Fuminori Katsukawa
{"title":"Effect of overweight/obesity and metabolic syndrome on frailty in middle‐aged and older Japanese adults","authors":"Yuki Nishida, Yosuke Yamada, Satoshi Sasaki, Eiichiro Kanda, Yoshihiko Kanno, Tatsuhiko Anzai, Kunihiko Takahashi, Keita Yamauchi, Fuminori Katsukawa","doi":"10.1002/osp4.714","DOIUrl":"https://doi.org/10.1002/osp4.714","url":null,"abstract":"Abstract Background The potential for developing frailty exists in middle‐aged and older adults. While obesity and metabolic syndrome (MetS) increase the risk of frailty in older adults, this relationship remains unclear in middle‐aged adults, who are prone to developing lifestyle‐related diseases. Objective To examine the effect of overweight/obesity and MetS on frailty development in middle‐aged and older Japanese adults using real‐world data. Methods This nationwide cohort study used exhaustive health insurance claims data of 3,958,708 Japanese people from 2015 to 2019 provided by the Japan Health Insurance Association. Participants aged ≥35 and < 70 years who received health checkups in 2015 were included. Multivariate logistic regression was used to assess the effect of body mass index (BMI) and MetS or MetS components (i.e., diabetes, hypertension, and dyslipidemia) in 2015 on frailty risk assessed using the hospital frailty risk score in 2019. Additionally, a subgroup analysis was performed to examine the interaction effects of MetS components and 4‐year weight change (%) on frailty risk among participants who were overweight and obese (BMI ≥25 kg/m 2 ). Results In 2019, 7204 (0.2%) and 253,671 (6.4%) participants were at high and intermediate frailty risks, respectively. Obesity and MetS were independently associated with intermediate/high frailty risk (odds ratio (OR) 1.36, p < 0.05; OR 1.23, p < 0.05, respectively) and high frailty risk (OR 1.80, p < 0.05; OR 1.37, p < 0.05, respectively) in all participants. Although all MetS components were frailty risk factors, these effects diminished with age in both sexes. Subgroup analysis of patients with diabetes revealed that 5%–10% weight loss was associated with reduced frailty risk in both sexes. Conclusions Obesity, MetS, and MetS components were independent frailty risk factors in middle‐aged and older Japanese adults. Weight loss of up to 10% over 4 years prevented frailty in patients with diabetes who were overweight and obese.","PeriodicalId":19448,"journal":{"name":"Obesity Science & Practice","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135477021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Trends in the burden of most common obesity‐related cancers in 16 Southern Africa Development Community countries, 1990‐2019. Findings from the Global Burden of Disease Study 1990 - 2019年南部非洲发展共同体16个国家最常见肥胖相关癌症负担趋势来自全球疾病负担研究的发现
Obesity Science & Practice Pub Date : 2023-09-27 DOI: 10.1002/osp4.715
Philimon Gona, Clara Gona, Suha Ballout, Chabila Mapoma, Sowmya Rao, Ali Mokdad
{"title":"Trends in the burden of most common obesity‐related cancers in 16 Southern Africa Development Community countries, 1990‐2019. Findings from the Global Burden of Disease Study","authors":"Philimon Gona, Clara Gona, Suha Ballout, Chabila Mapoma, Sowmya Rao, Ali Mokdad","doi":"10.1002/osp4.715","DOIUrl":"https://doi.org/10.1002/osp4.715","url":null,"abstract":"Abstract Background Obesity‐related cancers in the 16 Southern African Development Community (SADC) countries is quite prominent. The changes and time trends of the burden of obesity‐related cancers in developing countries like SADC remain largely unknown. A descriptive epidemiological analysis was conducted to assess the burden of obesity‐related cancers, (liver, esophageal, breast, prostate, colon/rectal, leukemia, ovarian, uterine, pancreatic, kidney, gallbladder/biliary tract, and thyroid cancers) in SADC countries. Methods Data from the 2019 Global Burden of Diseases (GBD) Study was used. Deaths extracted from vital registration, verbal autopsies and ICD codes. Cancer‐type, mortality and prevalence per 100,000 population and 95% uncertainty intervals (UIs) were calculated using the Cause of Death Ensemble model (CODEm) and Spatio‐Temporal Gaussian process with mixed effects regression models. Annual rates of change (AROCs) between 1990 and 2019 and the corresponding UIs were calculated. Results The top age‐standardized mortality rates per 100,000 in 2019 for males were leukemia, 20.1(14.4‐26.4), esophageal cancer, 15.1 (11.2‐19.1), and colon and rectal cancer, 10.3 (8.6‐12.6). For females, breast cancer, 20.6 (16.6‐25.0), leukemia, 17.1 (11.4‐23.7), and esophageal cancer, 8.3(5.5‐10.7), had the leading mortality rates. For males, AROC substantial (p<0.05) increase for kidney cancer for 11 of the countries (AROC from 0.41‐1.24%), colon cancer for eight of the countries (from 0.39‐0.92%), and pancreatic cancer for seven countries (from 0.26‐1.01%). In females, AROC showed substantial increase for pancreatic cancer for 13 of the countries from (0.34‐1.67%), nine countries for kidney cancer (from 0.27‐1.02%), seven countries each for breast cancer (0.35‐1.13%), and ovarian cancer (from 0.33‐1.21%). Conclusions There is need for location‐specific and culturally appropriate strategies for better nutrition and weight control, and improved screening for all cancers. Health promotion messaging should target kidney, colon, pancreatic, and breast cancers and encourage clinically tested methods of reducing BMI such as increasing personal physical activity and adoption of effective dietary regimes. This article is protected by copyright. All rights reserved.","PeriodicalId":19448,"journal":{"name":"Obesity Science & Practice","volume":"79 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135536098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Real world evidence on the characteristics of regular and intermittent users of a very‐low calorie diet program and associations with measures of program success, health, and quality of life 关于定期和间歇性极低卡路里饮食计划使用者特征的真实世界证据,以及与计划成功、健康和生活质量测量的关联
Obesity Science & Practice Pub Date : 2023-09-20 DOI: 10.1002/osp4.712
Patrice Jones, Michelle Blumfield, Emma Beckett, Skye Marshall, Kylie Abbott, Emily Duve, Flavia Fayet‐Moore
{"title":"Real world evidence on the characteristics of regular and intermittent users of a very‐low calorie diet program and associations with measures of program success, health, and quality of life","authors":"Patrice Jones, Michelle Blumfield, Emma Beckett, Skye Marshall, Kylie Abbott, Emily Duve, Flavia Fayet‐Moore","doi":"10.1002/osp4.712","DOIUrl":"https://doi.org/10.1002/osp4.712","url":null,"abstract":"Abstract Background Very low‐calorie diet (VLCD) programs are readily available in Australia. However, there is a lack of real‐world evidence describing the characteristics related to positive outcomes. Aims To examine the demographic, eating, self‐efficacy and program engagement characteristics of VLCD users in Australia, and the associations between user characteristics and program success, weight loss, quality of life (QOL) and health. Method Cross‐sectional data from Australian adults; regular users (n=189: VLCD user ≥4 days/week for >4 weeks) and intermittent users (n=111, VLCD user <4 weeks and/or <4 days/week). Self‐reported data on demographics, VLCD program use, support, eating behaviour, weight‐related QOL, mental health, physical health, self‐efficacy, and physical activity. Descriptive and inferential statistics were performed in R. Results Compared to regular users, intermittent users reported lower percentage weight loss (15.1%±SD 9.8 vs. 9.9%±SD 6.8, relative to starting weight), fewer reported their VLCD program as very successful (44% vs. 35%), higher depressive symptom scores (8.7±SD 2.8 vs. 6.7±SD 5.1), and lower general self‐efficacy (23.9±SD 4.7 vs. 29.4±SD5.7), nutrition self‐efficacy (11.9± SD 2.0 vs. 14.5± SD 3.1) and weight‐related QOL scores (60.9±SD 22.2 vs. 65.0±SD 11.8; p<0.001 for all). In regular users, older age and longer program duration were associated with greater total weight loss, support, and program success (p<0.001 for all). In intermittent users, program success was greater when dietitian support was used (OR 6.50) and for those with higher BMIs (OR 1.08, p<0.001 for all). In both groups, more frequent support was associated with better weight‐related QOL (p<0.001). Conclusion This study provides real‐world evidence that regular VLCD users had greater success and weight loss over intermittent program users. Findings may be used to tailor and improve the delivery of VLCD programs in Australia and other countries with retail access to VLCDs. This article is protected by copyright. All rights reserved.","PeriodicalId":19448,"journal":{"name":"Obesity Science & Practice","volume":"36 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136374480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Higher BMI is Strongly Linked to Poor Outcomes in Adult COVID‐19 Hospitalizations: A National Inpatient Sample Study 高BMI与成人COVID - 19住院治疗的不良结果密切相关:一项全国住院患者样本研究
Obesity Science & Practice Pub Date : 2023-09-11 DOI: 10.1002/osp4.692
Ahmed Elkhapery, Ali Abdelhay, Hemanth Krishna Boppana, Zeinab Abdalla, Mohamed Mohamed, Omar Al‐Ali, Anas Hashem, Amir Mahmoud, Eisa Mahmoud, Chengu Niu, Rami Dalbah, Ming‐Yan Chow
{"title":"Higher BMI is Strongly Linked to Poor Outcomes in Adult COVID‐19 Hospitalizations: A National Inpatient Sample Study","authors":"Ahmed Elkhapery, Ali Abdelhay, Hemanth Krishna Boppana, Zeinab Abdalla, Mohamed Mohamed, Omar Al‐Ali, Anas Hashem, Amir Mahmoud, Eisa Mahmoud, Chengu Niu, Rami Dalbah, Ming‐Yan Chow","doi":"10.1002/osp4.692","DOIUrl":"https://doi.org/10.1002/osp4.692","url":null,"abstract":"Abstract Aims The coronavirus disease 2019 (COVID‐19) pandemic has resulted in more than 6 million deaths worldwide. Studies on the impact of obesity on patients hospitalized with COVID‐19 pneumonia have been conflicting, with some studies describing worse outcomes in patients with obesity, while other studies reporting no difference in outcomes. Previous studies on obesity and critical illness have described improved outcomes in patients with obesity, termed the “obesity paradox.” The study assessed the impact of obesity on the outcomes of COVID‐19 hospitalizations, using a nationally representative database. Materials and Methods ICD‐10 code U071 was used to identify all hospitalizations with the principal diagnosis of COVID‐19 infection in the National Inpatient Database 2020. ICD‐10 codes were used to identify outcomes and comorbidities. Hospitalizations were grouped based on body mass index (BMI). Multivariable logistic regression was used to adjust for demographic characteristics and comorbidities. Results A total of 56,033 hospitalizations were identified. 48% were male, 49% were white and 22% were black. Patients hospitalized with COVID‐19 pneumonia in the setting of obesity and clinically severe obesity were often younger. Adjusted for differences in comorbidities, there was a significant increase in mortality, incidence of mechanical ventilation, shock, and sepsis with increased BMI. The mortality was highest among hospitalizations with BMI ≥60, with an adjusted odds ratio of 2.66 (95% Confidence interval 2.18–3.24) compared to hospitalizations with normal BMI. There were increased odds of mechanical ventilation across all BMI groups above normal, with the odds of mechanical ventilation increasing with increasing BMI. Conclusion The results show that obesity is independently associated with worse patient outcomes in COVID‐19 hospitalizations and is associated with higher in‐patient mortality and higher rates of mechanical ventilation. The underlying mechanism of this is unclear, and further studies are needed to investigate the cause of this.","PeriodicalId":19448,"journal":{"name":"Obesity Science & Practice","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135938176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correction to "Maternal vitamin D status in relation to infant BMI growth trajectories up to 2 years of age in two prospective pregnancy cohorts". 修正了“在两个预期怀孕队列中,母亲维生素D状态与婴儿2岁前BMI增长轨迹的关系”。
IF 2.2
Obesity Science & Practice Pub Date : 2023-08-01 DOI: 10.1002/osp4.664
{"title":"Correction to \"Maternal vitamin D status in relation to infant BMI growth trajectories up to 2 years of age in two prospective pregnancy cohorts\".","authors":"","doi":"10.1002/osp4.664","DOIUrl":"https://doi.org/10.1002/osp4.664","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.1002/osp4.602.].</p>","PeriodicalId":19448,"journal":{"name":"Obesity Science & Practice","volume":"9 4","pages":"440"},"PeriodicalIF":2.2,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10399519/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9955310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An intervention to decrease sedentary behavior in older adults: A secondary analysis of a randomized controlled trial. 减少老年人久坐行为的干预措施:一项随机对照试验的二次分析。
IF 1.9
Obesity Science & Practice Pub Date : 2023-06-15 eCollection Date: 2023-10-01 DOI: 10.1002/osp4.687
Nikita Abraham, Kate Lyden, Robert Boucher, Guo Wei, Victoria Gonce, Judy Carle, Katalin Fornadi, Mark A Supiano, Jesse Christensen, Srinivasan Beddhu
{"title":"An intervention to decrease sedentary behavior in older adults: A secondary analysis of a randomized controlled trial.","authors":"Nikita Abraham, Kate Lyden, Robert Boucher, Guo Wei, Victoria Gonce, Judy Carle, Katalin Fornadi, Mark A Supiano, Jesse Christensen, Srinivasan Beddhu","doi":"10.1002/osp4.687","DOIUrl":"10.1002/osp4.687","url":null,"abstract":"<p><strong>Background: </strong>Sedentary behaviors are associated with adverse health outcomes in older adults. The feasibility of behavioral interventions in this population is unclear.</p><p><strong>Methods: </strong>In the Sit Less, Interact, Move More (SLIMM) trial of 106 participants who had obesity, those randomized to the SLIMM intervention (<i>N</i> = 54) were instructed to replace sedentary activities with stepping. An accelerometer was used to measure physical activity. In this secondary analysis, mixed effect models were used to examine the effects of the SLIMM intervention on sedentary and stepping durations and steps/day by age (<70 and ≥ 70 years).</p><p><strong>Results: </strong>Mean ages in the <70 years (<i>N</i> = 47) and ≥70 years (<i>N</i> = 59) groups were 58 ± 11 and 78 ± 5. In the older subgroup, compared to standard-of-care (<i>N</i> = 29), the SLIMM intervention (<i>N</i> = 30) significantly increased stepping duration (13, 95%CI 1-24 min/d, <i>p</i> = 0.038) and steps per day (1330, 95% CI 322-2338, <i>p</i> = 0.01) and non-significantly decreased sedentary duration by (28,95% CI -61-5 min/d, <i>p</i> = 0.09). In the age <70 subgroup, there was no separation between the standard of care (<i>N</i> = 23) and SLIMM (<i>N</i> = 24) groups.</p><p><strong>Discussion: </strong>In older adults who had obesity, SLIMM intervention significantly increased stepping duration and steps per day. Interventions targeting sedentary behaviors by promoting low intensity physical activity may be feasible in this population.</p>","PeriodicalId":19448,"journal":{"name":"Obesity Science & Practice","volume":"9 5","pages":"529-537"},"PeriodicalIF":1.9,"publicationDate":"2023-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/54/f9/OSP4-9-529.PMC10551115.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41143173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Geographic differences in the magnitude of black-white disparities in having obesity. 黑人和白人肥胖程度差异的地理差异。
IF 1.9
Obesity Science & Practice Pub Date : 2023-05-26 eCollection Date: 2023-10-01 DOI: 10.1002/osp4.679
Steven A Cohen, Monique J Brown, Furong Xu, Caitlin C Nash, Mary L Greaney
{"title":"Geographic differences in the magnitude of black-white disparities in having obesity.","authors":"Steven A Cohen, Monique J Brown, Furong Xu, Caitlin C Nash, Mary L Greaney","doi":"10.1002/osp4.679","DOIUrl":"10.1002/osp4.679","url":null,"abstract":"<p><strong>Background: </strong>Obesity disparities in the United States are well documented, but the limited body of research suggests that geographic factors may alter the magnitude of these disparities. A growing body of evidence has identified a \"rural mortality penalty\" where morbidity and mortality rates are higher in rural than urban areas, even after controlling for other factors. Black-White differences in health and mortality are more pronounced in rural areas than in urban areas.</p><p><strong>Objective: </strong>Therefore, the purpose of this study was to explore how rural-urban status and region moderate Black-White health disparities in obesity.</p><p><strong>Methods: </strong>Data were abstracted from the 2012 Behavioral Risk Factor Surveillance System, with the sample being restricted to Black and White respondents (n = 403,231). Respondents' county of residence was linked to US Census information to obtain the county-level Index of Relative Rurality (IRR) and Census division. Crude and adjusted logistic regression models were utilized to assess the magnitude of Black-White disparities in having obesity (yes/no) by IRR quartile and by Census division.</p><p><strong>Results: </strong>Overall, Black-White differences in obesity were wider in rural than in urban counties, with a significant linear trend (p < 0.001). Furthermore, when stratified by US Census division, results revealed that disparities were significantly wider in rural than urban areas for respondents living in the Middle Atlantic and South Atlantic divisions. In contrast, the association was reversed for the remaining divisions (New England, East North Central, West North Central, Mountain, and Pacific), where the magnitude of the Black-White difference was the largest in urban areas.</p><p><strong>Conclusion: </strong>Findings highlight the need to understand and account for critical place-based factors that exacerbate racial obesity disparities to develop and maximize the effectiveness of policies and programs designed to reduce racial inequalities and improve population health.</p>","PeriodicalId":19448,"journal":{"name":"Obesity Science & Practice","volume":"9 5","pages":"516-528"},"PeriodicalIF":1.9,"publicationDate":"2023-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10551120/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41168134","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence of genetic causes of obesity in clinical practice. 临床实践中肥胖遗传原因的患病率。
IF 1.9
Obesity Science & Practice Pub Date : 2023-05-26 eCollection Date: 2023-10-01 DOI: 10.1002/osp4.671
Jaclyn Tamaroff, Dylan Williamson, James C Slaughter, Meng Xu, Gitanjali Srivastava, Ashley H Shoemaker
{"title":"Prevalence of genetic causes of obesity in clinical practice.","authors":"Jaclyn Tamaroff, Dylan Williamson, James C Slaughter, Meng Xu, Gitanjali Srivastava, Ashley H Shoemaker","doi":"10.1002/osp4.671","DOIUrl":"10.1002/osp4.671","url":null,"abstract":"<p><strong>Background: </strong>While obesity is common in the United States, monogenic obesity is rare, accounting for approximately 5% of individuals with obesity. New targeted therapies for genetic forms of obesity are available but there is limited guidance on who requires testing. The aims of this study were to evaluate the prevalence of potentially clinically significant variants among individuals in Pediatric Endocrinology or Medical Weight Center clinics at a single center and to identify clinical characteristics that may make genetic obesity more likely.</p><p><strong>Methods: </strong>Children and adults who had a genetic test for obesity, Uncovering Rare Obesity Gene panel, ordered during routine clinic visits from December 2019 to March 2021 were identified.</p><p><strong>Results: </strong>Of the 139 patients with testing ordered, 117 had available results and clinical data. Over 40% (52/117, 44%) had at least one positive result (variant) with a variant that is considered pathogenic, likely pathogenic, or a variant of uncertain significance. No association was detected between age, sex, race, and body mass index (BMI) or BMI <i>z</i>-score with a variant. Twenty-six individuals (22%) had one or more variants in genes associated with Bardet Biedl Syndrome, and 8 (6.8%) of them had pathogenic variants, higher than expected.</p><p><strong>Conclusion: </strong>Overall, clinical suspicion for genetic obesity is important in determining who requires genetic testing but no clinical factors were found to predict results. While obesity is multifactorial, novel medications for genetic forms of obesity indicate the need for evidence-based guidelines for who requires genetic testing for obesity.</p>","PeriodicalId":19448,"journal":{"name":"Obesity Science & Practice","volume":"9 5","pages":"508-515"},"PeriodicalIF":1.9,"publicationDate":"2023-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/c6/c9/OSP4-9-508.PMC10551116.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41138896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Health care providers' attitudes and counseling behaviors related to obesity. 医疗保健提供者对肥胖的态度和咨询行为。
IF 1.9
Obesity Science & Practice Pub Date : 2023-05-25 eCollection Date: 2023-10-01 DOI: 10.1002/osp4.686
Marjanna Smith, Christine Gallagher, Deanne Weber, William H Dietz
{"title":"Health care providers' attitudes and counseling behaviors related to obesity.","authors":"Marjanna Smith, Christine Gallagher, Deanne Weber, William H Dietz","doi":"10.1002/osp4.686","DOIUrl":"10.1002/osp4.686","url":null,"abstract":"<p><strong>Background: </strong>Obesity affects over 42% of the U.S. adult population, yet it remains undertreated. Many healthcare providers are biased in their perceptions and attitudes regarding obesity management and lack knowledge about how to treat it.</p><p><strong>Methods: </strong>The authors analyzed the results of the 2021 DocStyles survey to examine primary care providers' treatment and perceptions of obesity. The sample consisted of primary care physicians and nurse practitioners/physician assistants. Questions assessed healthcare providers' attitudes and counseling behaviors related to obesity, including referrals, use of medical therapy, barriers to care, and perceived risk factors for obesity.</p><p><strong>Results: </strong>1168 primary care providers who treat obesity participated in the survey. About half of the providers reported referring patients for obesity treatment. Almost two-thirds of providers had prescribed anti-obesity medications in the last 12 months. Those who did not prescribe anti-obesity medications reported a lack of familiarity with the medications or concerns about safety. Over three-quarters of providers indicated at least one barrier to treating obesity. Over half of the providers reported that poverty and food insecurity contributed significantly to the high prevalence of obesity in communities of color.</p><p><strong>Conclusion: </strong>Increased familiarity with anti-obesity medications may improve treatment. Reasons for patients' low priority accorded to obesity care remain the focus of future research.</p>","PeriodicalId":19448,"journal":{"name":"Obesity Science & Practice","volume":"9 5","pages":"501-507"},"PeriodicalIF":1.9,"publicationDate":"2023-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10551113/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41139600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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