Obesity Science & Practice最新文献

{"title":"Body Composition Changes in Latino Population: Longitudinal Associations of Fat and Muscle Mass Indices.","authors":"Rosero-Revelo Ricardo, Mateo Tamayo, Ricardo Correa, Bartolome Burguera, Marcio L Griebeler","doi":"10.1002/osp4.70077","DOIUrl":"10.1002/osp4.70077","url":null,"abstract":"<p><strong>Background: </strong>BMI has limitations in assessing metabolic health, especially in diverse populations. Fat mass index (FMI) and skeletal muscle mass (SMM) are more accurate predictors of obesity-related risks. Redefining obesity as a fat accumulation disease highlights the need for body composition-focused assessments in clinical practice.</p><p><strong>Objectives: </strong>This study assessed body composition changes in a Latino population over 6 months, evaluating the utility of fat mass index (FMI) and skeletal muscle mass (SMM) in detecting significant variations and exploring associations with baseline characteristics.</p><p><strong>Methods: </strong>In this retrospective observational study, 1571 Latino patients were categorized into hypocaloric-high protein (HHP) and eucaloric-high protein (EHP) groups based on baseline BMI. Body composition was measured using bioelectrical impedance analysis at baseline and after 6 months. Chi-square tests evaluated categorical shifts in classifications, while multinomial logistic and linear regression models identified factors associated with fat and muscle mass changes, adjusting for sex, age, and baseline composition metrics.</p><p><strong>Results: </strong>Over 6 months, participants experienced significant reductions in body fat mass (31.24-27.25 kg, <i>p</i> < 0.001) and increases in skeletal muscle mass (24.31-25.85 kg, <i>p</i> < 0.001). In the HHP group, baseline FMI and age were significantly associated with fat mass changes, with younger individuals and those with lower baseline FMI being more prone to fat accumulation (<i>p</i> < 0.001). In both groups, higher baseline SMM was associated with greater likelihood of muscle loss and lower probability of muscle gain, suggesting a physiological ceiling effect (<i>p</i> < 0.001).</p><p><strong>Conclusions: </strong>FMI and SMM enhance clinical assessments by providing more individualized metrics for obesity management in Latino populations. These findings support the integration of body composition analysis into clinical practice for more precise evaluation of metabolic health beyond traditional BMI classifications.</p>","PeriodicalId":19448,"journal":{"name":"Obesity Science & Practice","volume":"11 3","pages":"e70077"},"PeriodicalIF":1.9,"publicationDate":"2025-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12199286/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144507149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prospective Associations Between Salivary Biomarkers of Inflammation and Body Mass Index in Adolescents.","authors":"Keri M Kemp, Catheryn A Orihuela, Douglas A Granger, Retta R Evans, Sylvie Mrug","doi":"10.1002/osp4.70081","DOIUrl":"10.1002/osp4.70081","url":null,"abstract":"<p><strong>Background: </strong>Childhood and adolescent obesity, which affects nearly 1 in 5 youth in the US, presents a pressing public health concern. Obesity is linked to chronic low-grade inflammation, which exacerbates comorbidities. Noninvasive tools are needed to monitor obesity-related inflammation and assess weight-management interventions in children and adolescents.</p><p><strong>Objective: </strong>This study investigated the associations between Body Mass Index z-score (BMIz) and salivary biomarkers: C-reactive protein (CRP), cytokines interleukin (IL)-1β, IL-6, IL-8, and tumor necrosis factor (TNF)-α.</p><p><strong>Methods: </strong>A sample of 280 adolescents (Mage = 12.1 years, SD = 0.44) was followed for 2 years (3 time points) from 2019 to 2021. An autoregressive cross-lagged path model was used to examine the prospective relationships between BMIz and salivary biomarkers.</p><p><strong>Results: </strong>Findings indicated a bidirectional relationship between BMIz and salivary CRP levels, suggesting a feed-forward cycle in which excessive weight gain and inflammation mutually amplify each other. Salivary cytokines were not associated with BMIz.</p><p><strong>Conclusions: </strong>This study underscores the utility of salivary CRP as a noninvasive biomarker for obesity-related inflammation. Monitoring salivary CRP levels could aid in targeting interventions to prevent obesity-related complications early in life.</p>","PeriodicalId":19448,"journal":{"name":"Obesity Science & Practice","volume":"11 3","pages":"e70081"},"PeriodicalIF":1.9,"publicationDate":"2025-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12181989/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144476186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring the Acceptability of the STOP Method for Addressing Weight Loss Misinformation on Social Media: An Interview Study.","authors":"Danielle E Jake-Schoffman, Chrishann Walcott, Hannah A Lavoie, Francesca Wilkins, Megan A McVay, Montserrat Carrera Seoane","doi":"10.1002/osp4.70080","DOIUrl":"10.1002/osp4.70080","url":null,"abstract":"<p><strong>Background: </strong>Adults attempting weight loss often seek information online, though high prevalence of health misinformation. We aimed to gather feedback on a novel video-based approach to support adults in navigating weight-related misinformation online.</p><p><strong>Methods: </strong>We developed three brief videos presenting our novel mnemonic approach, the <b>STOP</b> method: Is someone trying to <b>S</b>ell you something? Does it sound <b>T</b>oo good to be true? Is it <b>O</b>ut of step with messages from trusted sources? Does it focus on fast <b>P</b>rogress? Adults with BMI ≥ 25 kg/m² interested in weight management strategies provided feedback on the videos via semi-structured interviews. Interviews were transcribed verbatim and analyzed using an emerging theme approach.</p><p><strong>Results: </strong>Participants (<i>N</i> = 14) were 64.3% female, 57.1% non-Hispanic white, with a mean age of 44.6 ± 18.0 years and BMI 31.5 ± 4.3 kg/m². Interviews revealed several themes. Participants found the STOP method to be accessible and would recommend it to others. They felt the videos effectively introduced the STOP method and its application and had minor suggestions for improved clarity and suggestions regarding visual appeal and ways to promote video engagement.</p><p><strong>Conclusions: </strong>The STOP method was acceptable and the brief videos were well-received; the results will direct video refinement and further testing.</p>","PeriodicalId":19448,"journal":{"name":"Obesity Science & Practice","volume":"11 3","pages":"e70080"},"PeriodicalIF":1.9,"publicationDate":"2025-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12182187/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144476175","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of Glucagon-Like Peptide Agonist Therapy With Dietary Patterns in a Cross-Sectional Cohort.","authors":"Eric J Brandt, Kendrin Sonneville, Matthias Kirch, Tammy Chang","doi":"10.1002/osp4.70079","DOIUrl":"10.1002/osp4.70079","url":null,"abstract":"<p><strong>Background: </strong>Mechanisms by which glucagon-like peptide receptor agonists (GLPRAs) improve cardiovascular outcomes remain incompletely understood. Whether taking GLPRAs are associated with differential dietary patterns remains unknown.</p><p><strong>Methods: </strong>Data from the National Health and Nutrition Examination Survey (2009-2020) were used to match GLPRA users to non-users with exact matching. Dietary patterns were identified using principal component analysis.</p><p><strong>Results: </strong>The four dietary patterns were \"Standard American\", \"Legume-Heavy\", \"Animal Protein and Vegetable\", and \"Whole Food Carbohydrate\". In a multinomial logit model among matched cases (<i>n</i> = 127) and comparisons (<i>n</i> = 1264), taking a GLPRA (vs. not) was associated with lower alignment with the Legume-Heavy pattern (0.15 vs. 0.24, <i>p</i> = 0.01), but no difference for Standard American (0.29 vs. 0.29, <i>p</i> = 0.97), Animal Protein and Vegetable (0.30 vs. 0.22, <i>p</i> = 0.07), or Whole Food Carbohydrate patterns (0.26 vs. 0.25, <i>p</i> = 0.87). There was no difference in dietary quality based on taking or not taking GLPRAs (mean Healthy Eating Index 53.7 (12.1) versus 52.6 (12.3), <i>p</i> = 0.09).</p><p><strong>Conclusion: </strong>GLPRAs were associated with lower likelihood of legume-focused dietary pattern and no difference in dietary healthfulness. Without simultaneous improvement in dietary healthfulness, there is a risk of a missed opportunity to promote healthy dietary habits among those taking GLPRAs.</p>","PeriodicalId":19448,"journal":{"name":"Obesity Science & Practice","volume":"11 3","pages":"e70079"},"PeriodicalIF":1.9,"publicationDate":"2025-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12181988/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144476173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluating Abdominal Obesity by Waist Circumference, Anthropometric Indices and Bioelectrical Impedance Analysis: A Comparative Pilot Study.","authors":"Anastasiia Nahorna, Heiner Baur","doi":"10.1002/osp4.70078","DOIUrl":"10.1002/osp4.70078","url":null,"abstract":"<p><strong>Introduction: </strong>Abdominal obesity significantly increases the risk of various health conditions, making accurate assessment crucial for diagnosis and treatment. This study compares the effectiveness of anthropometric methods and conventional bioelectrical impedance analysis in evaluating abdominal obesity.</p><p><strong>Materials and methods: </strong>Twenty adults (10 males, 10 females; age 45 ± 11.4 years; height 170 ± 8.63 cm; body weight 91.3 ± 19.2 kg; BMI 31.7 ± 5.31 kg/m²) participated in a single-visit pilot study at the Bern Movement Lab at Bern University of Applied Sciences. Anthropometric measurements; including body weight, height, waist and hip circumferences; anthropometric indices; including BMI, waist-to-hip ratio, waist-to-height ratio and conventional bioelectrical impedance analysis were collected. Spearman's Rank Correlation was used for statistical analysis due to non-normal data distribution.</p><p><strong>Results: </strong>Waist circumference, waist-to-hip ratio, and waist-to-height ratio consistently classified all participants as having abdominal obesity. In contrast, bioelectrical impedance analysis identified fewer cases, with only 40% of men and 10% of women classified as having abdominal obesity. Strong correlations were observed between waist circumference, waist-to-height ratio, and visceral fat, whereas waist-to-hip ratio showed weaker correlations.</p><p><strong>Conclusions: </strong>Simple anthropometric methods such as waist circumference, waist-to-hip ratio, and waist-to-height ratio are useful for evaluating abdominal obesity, with waist-to-height ratio often considered a more reliable predictor of central obesity. However, bioelectrical impedance analysis shows inconsistencies, and the waist-to-height ratio should be considered as a standard metric in future guidelines. Large-scale multiethnic studies are recommended to validate these findings.</p>","PeriodicalId":19448,"journal":{"name":"Obesity Science & Practice","volume":"11 3","pages":"e70078"},"PeriodicalIF":1.9,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12180561/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144476174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of Obesity on Appetite-Related Behaviors and Biomarkers in Older Adults: A Cross-Sectional Study.","authors":"Sean J Iwamoto, Tanya M Halliday, Jason R Tregellas, Kristina T Legget, Allison K Hild, Marc-André Cornier","doi":"10.1002/osp4.70076","DOIUrl":"10.1002/osp4.70076","url":null,"abstract":"<p><strong>Objective: </strong>Although aging is associated with reduced hunger and energy intake (EI), obesity is increasing in older adults. This study aimed to identify appetite regulation differences between older adults with obesity and older adults with normal weight (NW).</p><p><strong>Methods: </strong>This cross-sectional study recruited older adults with obesity (BMI 30-40 kg/m²) and NW (BMI < 25 kg/m²) aged 65-85 years. Fasting appetite-related behavioral questionnaires were collected. Ghrelin, polypeptide YY [PYY], glucagon-like peptide-1 [GLP-1], glucose, insulin, and triglycerides were measured fasting and every 30 min for 3 h following a test breakfast, and the incremental area under the curve (iAUC) was calculated.</p><p><strong>Results: </strong>13 older adults with obesity (aged 70.8 ± 4.0 years, 54% female, BMI 33.1 ± 3.6 kg/m²) and 14 with NW (aged 70.8 ± 5.3 years, 71% female, BMI 22.5 ± 2.1 kg/m²) were analyzed. Compared to older adults with NW, older adults with obesity had higher disinhibition and perceived hunger (<i>p</i> < 0.001 and <i>p</i> < 0.05, respectively), lower confidence in preventing overeating (<i>p</i> < 0.05), higher fasting GLP-1 and insulin (both <i>p</i> < 0.05), and higher PYY and insulin iAUCs (<i>p</i> < 0.01 and <i>p</i> < 0.05, respectively).</p><p><strong>Conclusion: </strong>Despite similar meal-related appetite and EI, older adults with obesity had higher fasting disinhibition, perceived hunger, GLP-1 and insulin, higher PYY and insulin iAUCs, and lower confidence in preventing overeating than those with NW. These differences between older adults with obesity and NW have implications for tailored obesity treatments in older adults.</p>","PeriodicalId":19448,"journal":{"name":"Obesity Science & Practice","volume":"11 3","pages":"e70076"},"PeriodicalIF":1.9,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12180562/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144476185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Confronting Pediatric Weight-Based Cybervictimization: Time for Action.","authors":"Silvia Zumaglini, Stephanie Fredrick, J Kevin Thompson, Myles S Faith","doi":"10.1002/osp4.70073","DOIUrl":"10.1002/osp4.70073","url":null,"abstract":"<p><p>Weight-based victimization represents a critical challenge for youth, particularly those with obesity, and has been linked to a range of negative psychological, academic, and behavioral outcomes. While research has extensively examined in-person victimization, the rise of digital platforms has given way to weight-based cybervictimization, which remains understudied. This paper highlights the urgent need for research, prevention, and intervention strategies focused on weight-based cybervictimization, emphasizing its harmful effects and its overlap with traditional forms of victimization. It identifies gaps in the existing literature, particularly regarding the inconsistent use of assessment tools and terminology in research on weight-based victimization, and proposes the necessity for culturally relevant and validated measurement tools that accurately capture youth experiences. Finally, it aims to inform best practices for healthcare providers, educators, and parents by promoting strategies that effectively address and mitigate the impact of weight-based victimization among youth.</p>","PeriodicalId":19448,"journal":{"name":"Obesity Science & Practice","volume":"11 3","pages":"e70073"},"PeriodicalIF":1.9,"publicationDate":"2025-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12178210/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144333574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Views Among the General Public on New Anti-Obesity Medications and on the Perception of Obesity as a Failure of Willpower.","authors":"Maya Goldkorn, Barry Schwartz, John Monterosso","doi":"10.1002/osp4.70041","DOIUrl":"https://doi.org/10.1002/osp4.70041","url":null,"abstract":"<p><strong>Background: </strong>The experience of obesity stigma is associated with negative clinical outcomes that include increased mental health problems and additional weight gain. Researchers have treated the public view that obesity is caused by poor willpower as both an <i>element</i> of obesity stigma and as a <i>cause</i> of obesity stigma. Here we test the hypothesis that awareness of new and effective glucagon-like peptide receptor agonist anti-obesity medications (AOMs) will encourage the view that obesity is a biologically-determined medical condition rather than a personal willpower failure and thereby lessen obesity stigma.</p><p><strong>Materials and methods: </strong>Two questionnaire studies, in which participants were randomly assigned to either read about the success of AOMs or to read various alternative material (<i>N</i> = 640 in total), investigated the effect that AOM awareness has on views of obesity.</p><p><strong>Results: </strong>Contrary to the study hypotheses, reading about AOMs did not increase the degree to which participants viewed obesity as a medical condition, nor did it reduce the role willpower failure was believed to play in obesity. Across conditions, participants reporting more personal success in weight loss without medication indicated greater belief that obesity was amenable to self-control, expressed greater obesity stigma, and held less positive attitudes toward the use of AOMs to manage weight.</p><p><strong>Conclusion: </strong>Taken together, these two studies provide no evidence that the success of AOMs will, in the short-term, lead to changes in how people view the etiology of obesity or to a reduction in obesity stigma. Correlational data suggest the possibility that blame and stigma associated with obesity may be robustly informed by participants' understanding of their own experiences managing weight.</p>","PeriodicalId":19448,"journal":{"name":"Obesity Science & Practice","volume":"11 2","pages":"e70041"},"PeriodicalIF":1.9,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12012989/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144024786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An Assessment of the Long-Term Efficacy of an Undergraduate Curriculum-Embedded Weight Bias Intervention in Practicing Registered Nurses.","authors":"Caroline Hallen Moore, Tracy L Oliver, Elizabeth B Dowdell, Justus Randolph, Amanda Davis","doi":"10.1002/osp4.70072","DOIUrl":"https://doi.org/10.1002/osp4.70072","url":null,"abstract":"<p><strong>Background: </strong>Individuals with obesity often experience weight bias in healthcare, which may negatively impact health outcomes. Weight bias (WB) can be reduced by provider participation in weight bias interventions. This mixed-methods study investigated the sustainability of reduced WB in those who received a weight bias intervention.</p><p><strong>Method: </strong>Registered nurses (RNs) who completed a weight bias intervention during their nursing education and those who did not were recruited to complete an online survey. WB scores and approaches towards caring for patients with obesity were compared.</p><p><strong>Results: </strong>Eighty-four RNs (50 intervention; 34 control) participated. Reduced WB was sustained over 4 and 6 years compared to pre-intervention scores (<i>p</i> < 0.001). No significant WB differences were found between the groups (<i>p</i> = 0.501). Thematic analysis identified three overarching themes: <i>physical care differences</i>, <i>recognition of obesity's causality and controllability,</i> and <i>equal treatment of all patients</i>.</p><p><strong>Conclusions: </strong>Weight bias intervention effects were sustained, but non-intervention nurses had comparable WB scores, indicating multifaceted influences on WB in clinical practice. In order for nurses to provide unbiased care for individuals with obesity, it is important to develop and implement both high-impact educational interventions that support reduced weight bias and organizational and structural supports in the practice environment.</p>","PeriodicalId":19448,"journal":{"name":"Obesity Science & Practice","volume":"11 2","pages":"e70072"},"PeriodicalIF":1.9,"publicationDate":"2025-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11988204/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144030237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predicting Pregnancy in Preconception Weight Loss Trials: Is it Possible?","authors":"Jacqueline F Hayes, Suzanne Phelan, Elissa Jelalian, Aaron B Caughey, Kristin Castorino, Casey Heaney, Angelica Mchugh, Rena R Wing","doi":"10.1002/osp4.70060","DOIUrl":"10.1002/osp4.70060","url":null,"abstract":"<p><strong>Introduction: </strong>Predicting pregnancy is a challenge in preconception weight loss intervention trials. The current study examined whether self-reported pregnancy likelihood and timing were predictive of conception.</p><p><strong>Methods: </strong>Adults (<i>n</i> = 184; 58% Hispanic; age = 33.4 ± 5.1; BMI = 33.6 ± 6.6) with overweight or obesity, prior gestational diabetes mellitus, and plans to become pregnant participated in a pre-conception behavioral weight loss intervention or control. At baseline, participants reported their estimated likelihood of pregnancy from 1 to 10 (categorized as low [1-3], medium [4-7], and high [8-10] likelihood); they also reported expected timeframe for pregnancy.</p><p><strong>Results: </strong>Over the 4-year trial, 62 (30%) participants became pregnant. Participants who reported a high likelihood of pregnancy were more likely to conceive than those with a lower rating (45.7% vs. 21.1%). The sensitivity and specificity of a high likelihood rating predicting conception were 69%, 95% CI (56.2%, 80.1%), and 58%, 95% CI (48.9%, 67.0%), respectively. Among those who conceived, mean expected time to pregnancy was 21.6 ± 13.2 months while actual mean time was 11.3 ± 9.1 months. Baseline age, ethnicity, parity, BMI, income, and other demographics did not predict conception.</p><p><strong>Conclusions: </strong>Pregnancy likelihood estimates best predicted conception, but sensitivity and specificity were low. Future work may consider additional ways to screen for likelihood of conception in preconception trials.</p>","PeriodicalId":19448,"journal":{"name":"Obesity Science & Practice","volume":"11 2","pages":"e70060"},"PeriodicalIF":1.9,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11975599/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143812051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}