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Optic Neuritis and Short-Segment Myelitis Following ChAdOx1 Adenovirus Vector-Based Vaccination: A Case Report. 基于ChAdOx1腺病毒载体接种视神经炎和短节段脊髓炎1例报告
IF 0.9 3区 医学
Neurology India Pub Date : 2024-11-01 Epub Date: 2024-12-17 DOI: 10.4103/ni.ni_410_22
Ravindra Kumar Garg, Praveen Kumar Sharma, Rajarshi Chakraborty, Anit Parihar
{"title":"Optic Neuritis and Short-Segment Myelitis Following ChAdOx1 Adenovirus Vector-Based Vaccination: A Case Report.","authors":"Ravindra Kumar Garg, Praveen Kumar Sharma, Rajarshi Chakraborty, Anit Parihar","doi":"10.4103/ni.ni_410_22","DOIUrl":"10.4103/ni.ni_410_22","url":null,"abstract":"","PeriodicalId":19429,"journal":{"name":"Neurology India","volume":"72 6","pages":"1280-1282"},"PeriodicalIF":0.9,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142847272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Schwannomas of C1: A Novel Classification and Description of Growth Patterns Based on a Personal Series and Review of Literature. C1神经鞘瘤：基于个人丛书和文献综述的一种新的生长模式分类和描述。
IF 0.9 3区 医学
Neurology India Pub Date : 2024-11-01 Epub Date: 2024-12-17 DOI: 10.4103/neurol-india.Neurol-India-D-24-00150
Krish Sridhar
{"title":"Schwannomas of C1: A Novel Classification and Description of Growth Patterns Based on a Personal Series and Review of Literature.","authors":"Krish Sridhar","doi":"10.4103/neurol-india.Neurol-India-D-24-00150","DOIUrl":"10.4103/neurol-india.Neurol-India-D-24-00150","url":null,"abstract":"<p><strong>Background: </strong>Schwannomas of C1 are rare tumors. Because of the wide variation in their anatomy, and presentation and their rarity, there is no proper understanding of their pathological anatomy nor their optimal management.</p><p><strong>Methods: </strong>A retrospective study of the C1 schwannomas operated by the author between 2000 and 2020 and a PubMed-based search of English literature were done to analyze data on the location and extent of the lesions, surgical approaches used, and operative outcomes. Using this data, a classification system was created indicating the location and extent of these lesions, depending on whether they were extradural (E) or intradural (I); with further subdivisions based on their relation to the vertebral artery, and cervicomedullary junction (CMJ).</p><p><strong>Results: </strong>Six patients with C1 schwannoma were operated by the author in the said period. Literature search yielded 44 cases in 16 publications. The details of location and extent of tumor were available in 22 patients including six of this article. Most of the tumors were intradural (13/22), with six in intradural and extradural compartments. Specific growth patterns were identified and a theory for this is proposed. Different surgical approaches were used; the far lateral and the posterolateral in 9 patients each, and the posterior midline in 7 of 25 patients. Using the available data, preferred surgical approaches are also presented.</p><p><strong>Conclusions: </strong>C1 schwannomas are a rare and complex group of tumors. The classification presented will help in understanding the growth pattern and pathological anatomy and choose the preferred surgical approach.</p>","PeriodicalId":19429,"journal":{"name":"Neurology India","volume":"72 6","pages":"1223-1230"},"PeriodicalIF":0.9,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142847301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sporadic Late-Onset Nemaline Rod Myopathy: An Interesting Case. 散发性迟发性线状杆肌病：一个有趣的病例。
IF 0.9 3区 医学
Neurology India Pub Date : 2024-11-01 Epub Date: 2024-12-17 DOI: 10.4103/ni.ni_1008_21
Anubhav Narwal, Mohit Mann, Achal K Srivastava, Mehar C Sharma
{"title":"Sporadic Late-Onset Nemaline Rod Myopathy: An Interesting Case.","authors":"Anubhav Narwal, Mohit Mann, Achal K Srivastava, Mehar C Sharma","doi":"10.4103/ni.ni_1008_21","DOIUrl":"10.4103/ni.ni_1008_21","url":null,"abstract":"<p><p>Sporadic late-onset nemaline rod myopathy is a rare, acquired, sub-acute, adult-onset myopathy characterized by proximal muscle weakness and nemaline rods in the myofibers. In contrast to its congenital form, the prevalence in adult population is comparatively rare. Herein, we report a case of 60-year-old male who presented with insidious onset proximal muscle weakness with myopathic pattern on electromyography. Histopathological examination showed type 1 and 2 muscle fiber atrophy with minimal chronic inflammatory cell infiltrate. Modified Gomori trichrome staining revealed granular deposits in the myofibers. Ultrastructure examination showed numerous nemaline rods in the myofibers; hence, the diagnosis of sporadic late-onset nemaline myopathy was rendered. Its association with monoclonal protein has been reported in the past. One should be aware of this rare entity as without correct diagnosis, there can be treatment failure and unfavorable outcome.</p>","PeriodicalId":19429,"journal":{"name":"Neurology India","volume":"72 6","pages":"1270-1272"},"PeriodicalIF":0.9,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142847305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Surgical Construction of Wide-Neck Bifurcation Experimental Aneurysm in an In Vivo Canine Model to Test Neurovascular Device. 在活体犬模型中通过手术构建宽颈分叉实验性动脉瘤，以测试神经血管装置。
IF 0.9 3区 医学
Neurology India Pub Date : 2024-11-01 Epub Date: 2024-12-17 DOI: 10.4103/ni.ni_1002_22
Kuhyun Yang, Hong Bum Kim, Woong Sub Park
{"title":"Surgical Construction of Wide-Neck Bifurcation Experimental Aneurysm in an In Vivo Canine Model to Test Neurovascular Device.","authors":"Kuhyun Yang, Hong Bum Kim, Woong Sub Park","doi":"10.4103/ni.ni_1002_22","DOIUrl":"10.4103/ni.ni_1002_22","url":null,"abstract":"<p><p>Stents are increasingly used for coiling difficult aneurysms, to reduce the risk of recurrences, or to modify blood flow. Currently, available bifurcation aneurysm models are ill-suited to assess stent performance before clinical use. We designed a new animal model of wide-neck canine Y-type bifurcation aneurysm (such as middle cerebral artery (MCA) bifurcation) and previously reported one of T-type (such as basilar bifurcation). Its potential value as a training tool as well as in the evaluation of new techniques or stent or embolic agents was assessed. Seven canine aneurysms were created (three: Y-type, four: T-type). Aneurysms were followed by transfemoral cerebral angiography (TFCA) and computed tomography angiography (CTA). We performed TFCA and self-expandable stent placement for the parent artery adjoined to the aneurysmal neck in one month's follow-up. We assessed the long-term patency of the parent artery with CTA and euthanasia and got a specimen for pathologic study at six months' follow-up. In six models except one (T-type), a wide-neck bifurcation aneurysm was created successfully and they showed good long-term patency at six months' follow-up. Stent placement was technically difficult in these cases, but did not lead to aneurysm thrombosis in CTA or neointimal closure of the aneurysm neck in pathologic finding at postoperative six months later. This model may be suitable for studying the effects of endovascular treatment on aneurysm and branch occlusion rates, for preclinical testing of stents and other intravascular devices, and for training students in endovascular technique.</p>","PeriodicalId":19429,"journal":{"name":"Neurology India","volume":"72 6","pages":"1241-1245"},"PeriodicalIF":0.9,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142847331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Effect of Acute Stroke Treatment on S100B, IMA, and Thiol-Disulfide Balance. 急性脑卒中治疗对S100B、IMA和硫醇-二硫平衡的影响。
IF 0.9 3区 医学
Neurology India Pub Date : 2024-11-01 Epub Date: 2024-12-17 DOI: 10.4103/ni.ni_511_22
Edip Varan, Esra F Oguz, Salim Neselioglu, Özcan Erel, Hesna Bektas
{"title":"The Effect of Acute Stroke Treatment on S100B, IMA, and Thiol-Disulfide Balance.","authors":"Edip Varan, Esra F Oguz, Salim Neselioglu, Özcan Erel, Hesna Bektas","doi":"10.4103/ni.ni_511_22","DOIUrl":"10.4103/ni.ni_511_22","url":null,"abstract":"<p><strong>Background: </strong>A variety of processes, ranging from blood-brain barrier disruption to circulating biomarkers, contributes to reperfusion injury in acute stroke treatment.</p><p><strong>Objective: </strong>We aimed to investigate the effects of thrombolytic therapy and endovascular thrombectomy therapy on serum S100 calcium-binding protein B, ischemia-modified albumin and thiol-disulfide balance in patients who arrived within the first 6 h of acute ischemic stroke.</p><p><strong>Material and methods: </strong>The study considered 66 patients with the diagnosis of acute ischemic stroke who underwent thrombolytic therapy or EVT in the first 6 h, as well as 32 healthy volunteers. Venous blood samples were collected before tPA and EVT and 24 h after treatment. S100B, native thiol, disulfide, total thiol, and Ischemia-modified albumin (IMA) levels were measured.</p><p><strong>Results: </strong>The S100B, total thiol, and native thiol values of the patients in the tPA group before and after the treatment showed statistical significance (P < 0.001). S100B, total thiol, and native thiol values were shown to be lower. The disulfide and IMA values of the patients in the tPA group did not differ significantly (respectively, P = 0.302, P = 0.054). However, disulfide and IMA levels were found to increase after treatment compared to pretreatment. The patients in the EVT group showed a significant difference in terms of S100B values (P < 0.001) and IMA values (P = 0.024).</p><p><strong>Conclusions: </strong>Determining how to protect the brain from free radical damage is important. More research should be carried out on treatments that prevent free radical damage in ischemia-reperfusion injury, as well as treatments for acute ischemic stroke.</p>","PeriodicalId":19429,"journal":{"name":"Neurology India","volume":"72 6","pages":"1231-1236"},"PeriodicalIF":0.9,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142847335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Learning Curve - A Neurosurgeon's Memoirs. 学习曲线——一位神经外科医生的回忆录。
IF 0.9 3区 医学
Neurology India Pub Date : 2024-11-01 Epub Date: 2024-12-17 DOI: 10.4103/neurol-india.neurol-india_100_24
S Vsm Venkataraman Veteran
{"title":"The Learning Curve - A Neurosurgeon's Memoirs.","authors":"S Vsm Venkataraman Veteran","doi":"10.4103/neurol-india.neurol-india_100_24","DOIUrl":"10.4103/neurol-india.neurol-india_100_24","url":null,"abstract":"","PeriodicalId":19429,"journal":{"name":"Neurology India","volume":"72 6","pages":"1327-1328"},"PeriodicalIF":0.9,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142847339","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Traumatic Brain Injury in the Elderly - A "Growing Epidemic". 老年人的创伤性脑损伤--一种 "日益严重的流行病"。
IF 0.9 3区 医学
Neurology India Pub Date : 2024-11-01 Epub Date: 2024-12-17 DOI: 10.4103/neurol-india.neurol-india_102_24
R Girish Menon
{"title":"Traumatic Brain Injury in the Elderly - A \"Growing Epidemic\".","authors":"R Girish Menon","doi":"10.4103/neurol-india.neurol-india_102_24","DOIUrl":"10.4103/neurol-india.neurol-india_102_24","url":null,"abstract":"","PeriodicalId":19429,"journal":{"name":"Neurology India","volume":"72 6","pages":"1142-1143"},"PeriodicalIF":0.9,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142847349","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Pseudo Guillain Barre Syndrome (GBS) Presentation of Sjogren's Syndrome. 干燥综合征的伪格林-巴利综合征（GBS）表现。
IF 0.9 3区 医学
Neurology India Pub Date : 2024-11-01 Epub Date: 2024-12-17 DOI: 10.4103/ni.ni_4_23
Reshma S Shaik, Sandhya Manorenj
{"title":"A Pseudo Guillain Barre Syndrome (GBS) Presentation of Sjogren's Syndrome.","authors":"Reshma S Shaik, Sandhya Manorenj","doi":"10.4103/ni.ni_4_23","DOIUrl":"10.4103/ni.ni_4_23","url":null,"abstract":"","PeriodicalId":19429,"journal":{"name":"Neurology India","volume":"72 6","pages":"1283-1284"},"PeriodicalIF":0.9,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142847056","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Damaged Relay Station: EEG Neurofeedback Training in Isolated Bilateral Paramedian Thalamic Infarct. 受损的中继站：脑电图神经反馈训练在孤立的双侧旁脉丘脑梗死。
IF 0.9 3区 医学
Neurology India Pub Date : 2024-11-01 Epub Date: 2024-12-17 DOI: 10.4103/neuroindia.NI_605_20
Mohammed Afsar, Jamuna Rajeswaran
{"title":"Damaged Relay Station: EEG Neurofeedback Training in Isolated Bilateral Paramedian Thalamic Infarct.","authors":"Mohammed Afsar, Jamuna Rajeswaran","doi":"10.4103/neuroindia.NI_605_20","DOIUrl":"10.4103/neuroindia.NI_605_20","url":null,"abstract":"<p><p>Stroke is a major public health concern and leads to significant disability. Bilateral thalamic infarcts are rare and can result in severe and chronic cognitive and behavioral disturbances-apathy, personality change, executive dysfunctions, and anterograde amnesia. There is a paucity of literature on neuropsychological rehabilitation in patients with bilateral thalamic infarcts. Mr. M., a 51 years old, married male, a mechanical engineer, working as a supervisor was referred for neuropsychological assessment and rehabilitation with the diagnosis of bilateral paramedian thalamic infarct after seven months of stroke. A pre-post comprehensive neuropsychological assessment of his cognition, mood, and behavior was carried out. The patient received 40 sessions of EEG-Neurofeedback Training. The results showed significant improvement in sleep, motivation, and executive functions, however, there was no significant improvement in memory. The case represents the challenges in the memory rehabilitation of patients with bilateral thalamic lesions.</p>","PeriodicalId":19429,"journal":{"name":"Neurology India","volume":"72 6","pages":"1277-1279"},"PeriodicalIF":0.9,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142847166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
"Strokes" in MELAS are Actually Stroke-like Episodes Due To Metabolic Pathophysiology. MELAS中的“中风”实际上是由于代谢病理生理学引起的卒中样发作。
IF 0.9 3区 医学
Neurology India Pub Date : 2024-11-01 Epub Date: 2024-12-17 DOI: 10.4103/neurol-india.Neurol-India-D-24-00572
Josef Finsterer
{"title":"\"Strokes\" in MELAS are Actually Stroke-like Episodes Due To Metabolic Pathophysiology.","authors":"Josef Finsterer","doi":"10.4103/neurol-india.Neurol-India-D-24-00572","DOIUrl":"10.4103/neurol-india.Neurol-India-D-24-00572","url":null,"abstract":"","PeriodicalId":19429,"journal":{"name":"Neurology India","volume":"72 6","pages":"1287"},"PeriodicalIF":0.9,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142847048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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