Neurology IndiaPub Date : 2025-07-01Epub Date: 2025-06-18DOI: 10.4103/neuroindia.NI_190_20
Evgenii P Nuzhnyi, Ekaterina Y Fedotova, Natalya Y Abramycheva, Zoya V Surnina, Anna S Vetchinova, Maksim N Andreev, Sergei N Illarioshkin
{"title":"Two Cases of PNPLA6 -Associated Ataxia with Novel Mutations.","authors":"Evgenii P Nuzhnyi, Ekaterina Y Fedotova, Natalya Y Abramycheva, Zoya V Surnina, Anna S Vetchinova, Maksim N Andreev, Sergei N Illarioshkin","doi":"10.4103/neuroindia.NI_190_20","DOIUrl":"10.4103/neuroindia.NI_190_20","url":null,"abstract":"","PeriodicalId":19429,"journal":{"name":"Neurology India","volume":" ","pages":"844-846"},"PeriodicalIF":0.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144326446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Study on the Pattern of Spinal Cord Involvement in Type 2 Diabetes Mellitus Patients with and without Nerve Conduction Study-Proven Neuropathy: A Cross-Sectional Analytical Study.","authors":"Sruthi Vamadevan, Sudhir Saxena, Mritunjay Kumar, Khanak Nandolia, Ravikant","doi":"10.4103/neurol-india.Neurol-India-D-24-00258","DOIUrl":"https://doi.org/10.4103/neurol-india.Neurol-India-D-24-00258","url":null,"abstract":"<p><strong>Background: </strong>Diabetic myelopathy is the pathological changes in the spinal cord due to diabetes. Despite extensive histopathological evidence supporting spinal cord atrophy, only two in vivo studies have reported radiological spinal cord atrophy, without any electrophysiological correlation, in diabetic patients.</p><p><strong>Objective: </strong>Our study aims to determine the radiological and electrophysiological patterns of spinal cord involvement in patients with and without nerve conduction study-proven neuropathy.</p><p><strong>Methods and materials: </strong>A cross-sectional analytical study was conducted on all consenting type 2 diabetic patients, 18-65 years old, admitted to our diabetic ward after executing stringent inclusion and exclusion criteria. After screening and categorizing the patients for neuropathy via clinical and electrophysiological methods, the patients were subjected to magnetic resonance imaging of the cervical spine and somatosensory evoked potential to trace radiological and electrophysiological evidence of spinal cord involvement and also to make a comparison between neuropathy and non-neuropathy subjects.</p><p><strong>Findings: </strong>We demonstrated significant radiological spinal cord atrophy (P value 0.006) and electrophysiological slowing of conduction velocities within the spinal cord (P value <0.001) in patients with diabetic neuropathy as compared to diabetic patients without neuropathy. Furthermore, the post hoc analysis suggested a significant association of the severity of neuropathy with the severity of myelopathy (χ2 11.927, P value 0.003) and glycemic status (χ2 7.564, P value 0.023).</p><p><strong>Interpretation: </strong>The study demonstrates significant radiological and electrophysiological spinal cord involvement in diabetic neuropathy patients than in non-neuropathy patients. The severity of spinal cord involvement is associated with the severity of neuropathy.</p>","PeriodicalId":19429,"journal":{"name":"Neurology India","volume":"73 4","pages":"746-751"},"PeriodicalIF":0.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144699135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Neurology IndiaPub Date : 2025-07-01Epub Date: 2025-07-24DOI: 10.4103/neurol-india.Neurol-India-D-24-00355
T P Waseem Ahamed, Ved P Maurya, Lily Pal, Vivek Singh, Arun K Srivastava
{"title":"Malignant Transformation of Tentorial Schwannoma.","authors":"T P Waseem Ahamed, Ved P Maurya, Lily Pal, Vivek Singh, Arun K Srivastava","doi":"10.4103/neurol-india.Neurol-India-D-24-00355","DOIUrl":"10.4103/neurol-india.Neurol-India-D-24-00355","url":null,"abstract":"<p><p>Schwannomas are benign tumors derived from Schwann cells, usually seen in the peripheral nervous system. 6.8%-8.0% of all intracranial tumors are accounted by intracranial schwannomas. 90% of these arise from the eighth cranial nerve, less frequently from the fifth, seventh, and twelfth cranial nerves. Schwannomas of the central nervous system [CNS] not arising from cranial nerves are rare. The genesis of these schwannomas in these unusual locations is still controversial since Schwann cells are not a natural component of the CNS. Only 18 tentorial schwannoma [TS] cases have been reported. Interestingly, this is the first reported case of a tentorial schwannoma transforming into a malignant peripheral nerve sheath tumor [MPNST]. We present the case of a 45-year-old gentleman with a giant TS with supra- and infratentorial growth, without any features of neurofibromatosis, and unusual recurrence on follow-up.</p>","PeriodicalId":19429,"journal":{"name":"Neurology India","volume":"73 4","pages":"776-780"},"PeriodicalIF":0.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144699146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Neurology IndiaPub Date : 2025-07-01Epub Date: 2024-11-29DOI: 10.4103/ni.ni_1025_20
Krishnan Balagopal, Aju Mathew, A Muraleedharan, Kurian Babu
{"title":"Essential Thrombocythemia Presenting with Stroke and Pulmonary Embolism.","authors":"Krishnan Balagopal, Aju Mathew, A Muraleedharan, Kurian Babu","doi":"10.4103/ni.ni_1025_20","DOIUrl":"10.4103/ni.ni_1025_20","url":null,"abstract":"","PeriodicalId":19429,"journal":{"name":"Neurology India","volume":" ","pages":"898-900"},"PeriodicalIF":0.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142771028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Neurology IndiaPub Date : 2025-07-01Epub Date: 2025-02-19DOI: 10.4103/neuroindia.NI_1262_20
Githin B George, Jose K Paul, Praveen Panicker, Dileep Ramachandran, B Srikumar, Thomas Iype
{"title":"A Case Series of Eosinophilic Meningitis from Kerala.","authors":"Githin B George, Jose K Paul, Praveen Panicker, Dileep Ramachandran, B Srikumar, Thomas Iype","doi":"10.4103/neuroindia.NI_1262_20","DOIUrl":"10.4103/neuroindia.NI_1262_20","url":null,"abstract":"","PeriodicalId":19429,"journal":{"name":"Neurology India","volume":" ","pages":"892-894"},"PeriodicalIF":0.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143458753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Neurology IndiaPub Date : 2025-07-01Epub Date: 2025-02-19DOI: 10.4103/NI.NI_727_20
Prashant R Singh, Tarun K Pandey, Faran Ahmad, Devendra K Chhabra, Anju Shukla, Raghavendra K Sharma
{"title":"A Rare Case of Extra-Axial Frontal Schwannoma Mimicking Atypical Meningioma.","authors":"Prashant R Singh, Tarun K Pandey, Faran Ahmad, Devendra K Chhabra, Anju Shukla, Raghavendra K Sharma","doi":"10.4103/NI.NI_727_20","DOIUrl":"10.4103/NI.NI_727_20","url":null,"abstract":"","PeriodicalId":19429,"journal":{"name":"Neurology India","volume":" ","pages":"919-921"},"PeriodicalIF":0.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143458756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}