Neurology India最新文献

{"title":"Nonconvulsive Status Epilepticus in a Case with Down Syndrome.","authors":"Burcin Sanlıdag, Mehmet Alp Dirik, Eray Dirik","doi":"10.4103/neuroindia.NI_530_17","DOIUrl":"10.4103/neuroindia.NI_530_17","url":null,"abstract":"","PeriodicalId":19429,"journal":{"name":"Neurology India","volume":" ","pages":"868-869"},"PeriodicalIF":0.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144326436","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pediatric Foramen Ovale Dermoid Cyst: A Rare Case and Systematic Review of Middle Fossa Dermoid Cysts in Children.","authors":"Joseline Haizel-Cobbina, Saqib K Bakhshi, Michael Cools, Campbell Liles, Michael C Dewan","doi":"10.4103/neurol-india.Neurol-India-D-24-00137","DOIUrl":"10.4103/neurol-india.Neurol-India-D-24-00137","url":null,"abstract":"<p><p>Intracranial dermoid cysts are usually asymptomatic and discovered incidentally. In children, intracranial dermoid cysts occurring beyond the confines of the posterior cranial fossa are rare. We present the first case of an unruptured pediatric foramen ovale dermoid cyst with 18 months of follow-up along with a systematic review of the literature on middle fossa dermoid cysts in children. Using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, a literature search was conducted to identify all cases of pediatric middle fossa dermoid cysts. Uponcomprehensive review of the literature, we found only nine cases of middle cranial fossa dermoid cysts in children. Gross total resection was achieved in seven cases commonly via a subtemporal or pterional approach. All patients were alive at the last follow-up. Surgical resection of middle fossa dermoid cysts can be safely performed in children while protecting neurologic function and achieving durable radiographic results.</p>","PeriodicalId":19429,"journal":{"name":"Neurology India","volume":"73 4","pages":"770-775"},"PeriodicalIF":0.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144699080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reliability, Validity, and Feasibility of Customizable Ictal Testing Battery (C-ITB) for Assessing Cognitive Functions in Epilepsy Monitoring Unit (EMU).","authors":"Manjari Tripathi, Vasundhara Shukla, Pradeep Sura Reddy, Rekha Dwivedi, Shashank Tripathi, Rajesh Kumar Singh, Shailesh Gaikwad, Madhvi Tripathi, ChandraShekhar Bal, Ashima Nehra, Deepti Vibha, Sarat P Chandra","doi":"10.4103/neurol-india.Neurol-India-D-24-00251","DOIUrl":"10.4103/neurol-india.Neurol-India-D-24-00251","url":null,"abstract":"<p><strong>Background: </strong>Ictal cognitive assessments carried out in Epilepsy Monitoring Units (EMUs) have been standardized on the Western population which is unable to capture the socioeducational differences present in the Indian population.</p><p><strong>Objective: </strong>This study focuses on modifying and rearranging components of the International League Against Epilepsy's Ictal Testing Battery (ILAE-ITB) in a local setting at an Indian epilepsy center.</p><p><strong>Methods: </strong>The Customizable Ictal Testing Battery (C-ITB) was modified using ILAE-ITB by enabling variable order of item administration, prioritizing items testing the suspect seizure onset region. The consenting participants were assessed using both batteries. The diagnostic performance and localization ability of C-ITB were also measured.</p><p><strong>Results: </strong>116 patients with drug-resistant epilepsy were recruited. Association between both batteries was statistically significant using the Chi-square/Fisher's exact test (P value < 0.001). The Cohen's kappa was 85.6 and the sensitivity and specificity indices were 100% and 80% respectively. C-ITB demonstrated an inherent validity of 94.8%. There was a significant association between the localization demonstrated by C-ITB and vEEG, MRI. The localization capabilities of C-ITB and ILAE-ITB were comparable.</p><p><strong>Significance: </strong>C-ITB is a comprehensive measure of ictal functioning adapted according to the requirements of Indian patients with epilepsy and might facilitate further research into the domain of ictal response deficits.</p>","PeriodicalId":19429,"journal":{"name":"Neurology India","volume":"73 4","pages":"740-745"},"PeriodicalIF":0.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144699085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effect of Total Intravenous Anesthesia and Inhalational Anesthesia on the Markers of Neuronal and Systemic Inflammation in Patients Undergoing Resection of Supratentorial Gliomas (TINSI Trial): Study Protocol for a Randomized Controlled Trial.","authors":"Sreeja Ravindranath, Ajay Prasad Hrishi, Ranganatha Praveen, Manikandan Sethuraman, Krishnakumar Keshavapisharady, U K Madhusoodanan","doi":"10.4103/neurol-india.Neurol-India-D-24-00488","DOIUrl":"10.4103/neurol-india.Neurol-India-D-24-00488","url":null,"abstract":"<p><p>Brain tumors and craniotomy surgeries can induce both systemic and neuronal inflammation. Currently, there is a limited amount of literature addressing the influence of anesthetic agents on neuronal and systemic inflammation in neurosurgical settings and its impact on the occurrence of postoperative neurocognitive dysfunction (PND). Our primary objective is to assess the effects of propofol-based total intravenous anesthesia (TIVA) compared to sevoflurane inhalational anesthesia (INHA) with respect to the levels of perioperative inflammatory markers, specifically neuron-specific enolase (NSE) and interleukin-6 (IL-6) in patients undergoing craniotomy for supratentorial tumor surgery. Our secondary objective is to evaluate the correlation of neuronal, systemic inflammatory markers, and the incidence of PND and functional outcomes in patients receiving TIVA versus INHA for supratentorial tumor surgeries. This study protocol details the methodology of a prospective, randomized, and single-center trial approved by the Institutional Ethics Committee and registered with the Clinical Trial Registry of India. The study focuses on patients undergoing craniotomy for supratentorial glioma decompression. Assessing changes in the biomarker level is the primary objective and correlation of this change in biomarker with PND and functional outcome is our secondary objective. The sample size of 45 patients in each group was calculated using n master software by considering alpha of 5%, power of 80%, a mean difference of 79.2 between the groups, and an effect size of 0.603. We describe the study protocol of the single-center trial. The first patient was recruited on September 17, 2023, and we will complete recruitment before March 2025. Our study is expected to inform the impact of anesthesia technique on the biomarkers of the inflammation and consequently PND. Knowledge about this will help the anesthesiologist to select the appropriate anesthetic drug in their clinical practice.</p>","PeriodicalId":19429,"journal":{"name":"Neurology India","volume":"73 4","pages":"764-769"},"PeriodicalIF":0.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144699088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Mercedes Benz Approach to the Lumbosacral Junction: A Technical Note.","authors":"Venugopal K Menon, Mandar Borde, Umesh P Kanade, Renjit K Jayavhandran, Mantu Jain","doi":"10.4103/neurol-india.Neurol-India-D-24-00218","DOIUrl":"10.4103/neurol-india.Neurol-India-D-24-00218","url":null,"abstract":"<p><p>Posterior midline incision is the standard approach to the lumbosacral junction (LSJ). However, this approach has many limitations and can have complications. Few other incisions have been described but are mostly confined to sacral tumor excisions and often not suited to lumbosacral fixations. The authors describe the \"Mercedes Benz\" incision (MBI), which they have used extensively over the past two decades with satisfaction. The present report is a step-by-step guidance of the technical details of this novel approach and illustration of three cases. MBI approach is anatomical and therefore reduces denervation. MBI, by the approach described by the authors, provides excellent exposure of the LSJ, including the ilium, and can have wide indications with minimal complications.</p>","PeriodicalId":19429,"journal":{"name":"Neurology India","volume":"73 4","pages":"758-763"},"PeriodicalIF":0.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144699089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Middle Cranial Fossa Approach for Surgical Repair of Superior Semicircular Canal Dehiscence and Tegmen Defect: Operative Video of Two Illustrative Cases.","authors":"Kautilya R Patel, Daniel L Surdell, Geoffrey Casazza, Anne K Maxwell, Sara Wattier, Mithun G Sattur","doi":"10.4103/neurol-india.Neurol-India-D-25-00078","DOIUrl":"https://doi.org/10.4103/neurol-india.Neurol-India-D-25-00078","url":null,"abstract":"","PeriodicalId":19429,"journal":{"name":"Neurology India","volume":"73 4","pages":"692-695"},"PeriodicalIF":0.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144699078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Carotid Stenting of Multichannel Pseudoocclusion of Internal Carotid Artery using 5-French Picard as a Supporting Catheter for Microwire Navigation Across Tight Stenosis: Report of Two Cases.","authors":"Anshu Mahajan, Gaurav Goel, Biplab Das, Vinit Banga","doi":"10.4103/neuroindia.NI_854_18","DOIUrl":"10.4103/neuroindia.NI_854_18","url":null,"abstract":"","PeriodicalId":19429,"journal":{"name":"Neurology India","volume":" ","pages":"889-891"},"PeriodicalIF":0.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143458818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Endoscopic Endonasal Approach to Occipital Condyle: Key to \"Far-Medial Approach\" - A Cadaveric Study.","authors":"Keyur G Shah, Srinivas Dwarakanath, Gyani J S Birua, Anita Mahadevan, Priya Ranganath","doi":"10.4103/neurol-india.Neurol-India-D-24-00788","DOIUrl":"10.4103/neurol-india.Neurol-India-D-24-00788","url":null,"abstract":"<p><strong>Background: </strong>We present a descriptive anatomical study for the endoscopic endonasal approach to occipital condyle.</p><p><strong>Objective: </strong>To describe the anatomy of various structures encountered during the expanded endoscopic endonasal approach to the occipital condyles and to elaborate on the technical steps for exposure while preventing injury to vital neurovascular structures on the way.</p><p><strong>Methods and materials: </strong>A total of 20 sides in ten human cadavers were evaluated for the research after obtaining informed consent. Cadavers were placed in a deep freezer at -20 degree Celsius before thawing 24 hours prior to the dissection. A standard 0-degree endoscope was used to aid in stepwise dissection to the occipital condyle. Anatomically significant photos and videos were recorded, and appropriate anatomical measurements were taken.</p><p><strong>Results: </strong>The mean distance from the tip of the nose to the anterior border of the occipital (ToN-aOC) was 10.8 cm, whereas the mean distance between tip of the nose and the anterior border of the hypoglossal canal (ToN-aHG) was 11.4 cm. The average intercondylar distance (aOC-aOC) and interhypoglossal canal distances (aHG-aHG) were 1.3 cm and 3.1 cm, respectively.</p><p><strong>Conclusions: </strong>This study serves as a stepwise guide for endoscopic endonasal approach to the occipital condyle. This approach warrants the innovation of new longer instruments in comparison to the transsphenoidal approach (15-17 cm vs 12-15 cm). Drilling of the anterior part of the occipital condyle, up to the hypoglossal canal, increases the surgical corridor in the lower lateral clivus.</p>","PeriodicalId":19429,"journal":{"name":"Neurology India","volume":"73 4","pages":"698-703"},"PeriodicalIF":0.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144699140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Post Scrotal Tap Morvan's Syndrome with Nephrotic Syndrome.","authors":"Chhatrapal Singh Sahu, Krishna Somani","doi":"10.4103/ni.ni_40_20","DOIUrl":"https://doi.org/10.4103/ni.ni_40_20","url":null,"abstract":"","PeriodicalId":19429,"journal":{"name":"Neurology India","volume":"73 4","pages":"850-852"},"PeriodicalIF":0.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144699081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cerebellopontine Angle Meningeal Melanocytoma: A Rare Case and Literature Review of Outcomes and Recurrences.","authors":"Geetha Sundar, Benak Shivalingappa, Geetha Vasudevan, G Lakshmi Prasad","doi":"10.4103/neurol-india.Neurol-India-D-24-00518","DOIUrl":"10.4103/neurol-india.Neurol-India-D-24-00518","url":null,"abstract":"<p><p>Melanocytes are neural crest derived cells. Intracranial meningeal melanocytomas (MM) are rare tumors that were first described in 1972. Authors report a rare case of a cerebellopontine (CP) angle MM. In addition, a literature review of CP angle MM is provided and compared with other cranial MMs in terms of recurrence and outcomes. A 45 year old male presented with tinnitus and occipital headache. He had mild sensorineural hearing loss. MRI showed an extra axial CP angle lesion that was hyperintense on T1 and hypointense on T2, with blooming on SWI sequences. A retrosigmoid craniotomy and near total resection was performed. Postoperatively, he developed paresis of the facial and lower cranial nerves, hemiparesis, developed pulmonary complications and died 3 months later. A total of 20 cases of CP angle MM were retrieved and analysed from literature. We noted significant differences between the overall cranial MM and CP angle MM in terms of recurrence and malignant transformation. The recurrence rate was 60%, the higher grade transformation rate was 10%, and mortality was 18%, which was higher than that of cranial MM in general. Authors believe that upfront adjuvant radiotherapy may possibly reduce the recurrence rates in this location.</p>","PeriodicalId":19429,"journal":{"name":"Neurology India","volume":"73 4","pages":"794-797"},"PeriodicalIF":0.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144699136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}