Neurology India最新文献

{"title":"The German Neurologist Joachim Bodamer Who Should Be Remembered and His Legacy to Neurology: \"Prosopagnosia\".","authors":"Hayriye Dilek Akdoğan, Ali Çağlar Turgut, Yaren Akdoğan, Fuyou Guo","doi":"10.4103/neurol-india.Neurol-India-D-25-00972","DOIUrl":"10.4103/neurol-india.Neurol-India-D-25-00972","url":null,"abstract":"","PeriodicalId":19429,"journal":{"name":"Neurology India","volume":"74 4","pages":"666-669"},"PeriodicalIF":0.8,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148536554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Curious Case of Cushing's Disease.","authors":"Kuntal K Das, Bibhuti B Mohanta, Arun K Srivastava","doi":"10.4103/neurol-india.Neurol-India-D-26-00568","DOIUrl":"10.4103/neurol-india.Neurol-India-D-26-00568","url":null,"abstract":"","PeriodicalId":19429,"journal":{"name":"Neurology India","volume":"74 4","pages":"604-605"},"PeriodicalIF":0.8,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148536579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Letter to the Editor on \"Rapid Progression and Atypical Imaging in Neurological Wilson's Disease\"-The Need to Find the Biomarkers Predicting the Severity of Neurological Disease.","authors":"Agnieszka Antos, Tomasz Litwin, Jan Paweł Bembenek","doi":"10.4103/neurol-india.Neurol-India-D-25-00309","DOIUrl":"10.4103/neurol-india.Neurol-India-D-25-00309","url":null,"abstract":"","PeriodicalId":19429,"journal":{"name":"Neurology India","volume":" ","pages":"695-696"},"PeriodicalIF":0.8,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146157864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of Balloon Guide Catheter and Non-Balloon Techniques in Middle Cerebral Artery (MCA) and Proximal M3 Occlusion Thrombectomy: A Retrospective Two-Center Study.","authors":"Wook-Joo Kim, Shang Hun Shin, Jung Min Choi, Sung Won Youn","doi":"10.4103/neurol-india.Neurol-India-D-25-00457","DOIUrl":"10.4103/neurol-india.Neurol-India-D-25-00457","url":null,"abstract":"<p><strong>Background: </strong>While balloon guide catheters (BGCs) are widely used during endovascular thrombectomy (EVT) for large vessel occlusions, prior studies evaluated heterogeneous occlusion locations. The specific benefits of BGCs in M1, or more distal middle cerebral artery (MCA) occlusions remain uncertain.</p><p><strong>Methods: </strong>We retrospectively analyzed 61 patients with acute ischemic stroke due to M1, M2, or proximal M3 occlusion who underwent EVT at two tertiary centers between January 2020 and December 2021. Patients were treated using the stent retriever thrombectomy (SRT), direct aspiration first-pass technique (ADAPT), or combined techniques, with or without BGC, at the operator's discretion. Primary endpoints were successful recanalization (mTICI ≥2b), first-pass recanalization, and procedural time. Clinical outcomes included the 90-day modified rankin scale (mRS), symptomatic intracranial hemorrhage, and mortality.</p><p><strong>Results: </strong>Among the 61 patients (mean age 68.9 ± 12.8 years), 35 (57.4%) were treated with BGC. Successful recanalization rates were similar between the BGC and non-BGC groups (88.6% vs. 92.3%, P = 0.960). However, first-pass recanalization was lower in the BGC group (42.9% vs. 69.2%, P = 0.041), and procedural time was longer (57.1 ± 29.6 vs. 38.4 ± 19.7 min, P = 0.005). No significant differences were observed in functional independence at 90 days (40.0% vs. 50.0%, P = 0.440), symptomatic hemorrhage, or mortality. In multivariate logistic regression adjusting for age, baseline NIHSS, occlusion site, and recanalization success, BGC use was not independently associated with good functional outcome.</p><p><strong>Conclusion: </strong>In M1 and more distal MCA occlusions, BGC use was not associated with improved angiographic or clinical outcomes and was linked to lower first-pass recanalization rates and longer procedural times. These exploratory findings indicate that the utility of BGCs may depend on the occlusion location and procedural context, supporting a more tailored approach to device selection rather than a uniform preference for BGC use.</p>","PeriodicalId":19429,"journal":{"name":"Neurology India","volume":"74 4","pages":"616-620"},"PeriodicalIF":0.8,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148536270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ordinary Differential Equation-Based Individualized Pharmacokinetic Simulation for Dose Optimization in an Infant with Global Developmental Delay and Drug-Resistant Epilepsy.","authors":"Archana Mishra, Krishna M Gulla, Rituparna Maiti, Debasish Hota, Anand Srinivasan","doi":"10.4103/neurol-india.Neurol-India-D-25-00261","DOIUrl":"10.4103/neurol-india.Neurol-India-D-25-00261","url":null,"abstract":"<p><strong>Abstract: </strong>In children with epilepsy associated with global developmental delay (GDD), around 10-20% experience refractory epilepsy, often requiring multiple antiseizure drugs (ASDs). These ASDs have narrow therapeutic indices. Therapeutic drug monitoring is crucial for optimizing ASD therapy. In this case, an infant with GDD with TBC1D24 mutation and refractory seizures was admitted with uncontrolled seizures despite multiple ASDs. The patient's serum levels of valproic acid, carbamazepine, and phenytoin were subtherapeutic. Simulations were performed by solving the pharmacokinetic ordinary differential equations numerically to optimize the dose. The modifications were made for valproate (240 mg every 4 h) and carbamazepine (100 mg thrice a day) to achieve therapeutic concentrations. Serum drug levels, after dose adjustment, were within the therapeutic range. The patient experienced no further seizure episodes. This case highlights the importance of individualized pharmacokinetic simulation in optimizing drug doses instead of empirical dose adjustments.</p>","PeriodicalId":19429,"journal":{"name":"Neurology India","volume":"74 4","pages":"670-674"},"PeriodicalIF":0.8,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148536453","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Suction Catheter as an Endoscopic Port for Simultaneous Real-Time Neuronavigation and Neuroendoscopy: A Technical Note.","authors":"Himanshu Prasad, J S Karthik, Bhaskar Suryanarayanan, Kshitij R Mahajan, Abhishek Prakash, Rajesh Lamba, Mayank Garg, Jaskaran S Gosal, Deepak K Jha","doi":"10.4103/neurol-india.Neurol-India-D-26-00268","DOIUrl":"10.4103/neurol-india.Neurol-India-D-26-00268","url":null,"abstract":"<p><strong>Abstract: </strong>The combined use of neuronavigation and neuroendoscopy enhances safety and accuracy during intraventricular procedures, particularly in pediatric patients with complex ventricular anatomy such as multiseptate hydrocephalus. However, conventional endoscopic sheaths and integrated systems often limit the simultaneous use of navigation, visualization, and endoscopic instruments. We describe a simple, cost-effective technical modification using a standard 14 Fr green suction catheter (approximately 4.7 mm internal diameter and 20 cm length) repurposed as a working conduit to allow simultaneous passage of a rigid neuroendoscope along with either a navigation wand or an interventional instrument such as a Fogarty catheter or monopolar cautery. The technique was successfully applied in an 8-month-old infant with congenital multiseptate hydrocephalus undergoing navigation-guided endoscopic septal fenestration. The modified conduit enabled uninterrupted real-time navigation and visualization, provided adequate working space for intervention, and eliminated the need for repeated instrument exchanges without intraoperative complications. A routinely available suction catheter can serve as an effective dual-channel endoscopic port, allowing simultaneous neuronavigation, neuroendoscopic visualization, and intraventricular intervention without additional cost.</p>","PeriodicalId":19429,"journal":{"name":"Neurology India","volume":"74 4","pages":"659-661"},"PeriodicalIF":0.8,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148536521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acute Cholecystitis as a Potentially Fatal Complication of Cerebrovascular Disease.","authors":"Hiroshi Yokota, Masahiro Terabe, Yuko Matsumoto, Daisuke Wajima, Yuki Ida, Hiroyuki Kubota, Hiroo Itoh","doi":"10.4103/neuroindia.NI_130_20","DOIUrl":"https://doi.org/10.4103/neuroindia.NI_130_20","url":null,"abstract":"<p><strong>Background/objective: </strong>Acute cholecystitis (AC) can occur as a potentially fatal complication in critically ill patients, with multiple risk factors such as old age, male sex, diabetes mellitus, and history of cardiovascular disease reported. Recently, a history of cerebrovascular disease (CVD) has been suggested as a risk factor for the development of a complication in which vascular disease pathogenic factors, including atherosclerosis and ischemia, may play a role. However, little has been reported about the occurrence of AC in patients who have experienced CVD. This study aimed to investigate the incidence and clinical details of AC after CVD.</p><p><strong>Methods: </strong>This was a retrospective review performed at a single institution. The records of all patients hospitalized with CVD were examined. In addition to the incidence of AC, atherosclerotic factors as well as previously reported risk factors were reviewed and then compared with those in patients with traumatic brain injury (TBI).</p><p><strong>Results: </strong>AC was identified in 4/156 (2.6%) patients with CVD and 1/135 (0.7%) patients with TBI, which was not a statistically significant difference ( P = 0.233). In addition, factors were comparable, except for hypertension, fever, and nonambulant status, which were found significantly more often in CVD patients. Notably, three of the four patients developed AC after recurrent CVD.</p><p><strong>Conclusions: </strong>AC can occur as a potentially fatal complication in CVD patients. In addition to nonspecific clinical findings, consciousness disturbance with neurological deficits may lead to delayed diagnosis. A prospective study with a larger cohort is warranted to clarify the relationship between AC development and CVD.</p>","PeriodicalId":19429,"journal":{"name":"Neurology India","volume":"74 4","pages":"637-641"},"PeriodicalIF":0.8,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148605729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Letting Nature Take Its Course: Harish Rana First case of Withdrawal of Life-Sustaining Treatment Under the Supreme Court Guidance.","authors":"Seema Mishra, Deepak K Gupta, Nishkarsh Gupta, Deepti Vibha, Sachidanand J Bharati, Rakesh Garg, Puneet Rathore, Suhana Sulfiker","doi":"10.4103/neurol-india.Neurol-India-D-26-00487","DOIUrl":"10.4103/neurol-india.Neurol-India-D-26-00487","url":null,"abstract":"","PeriodicalId":19429,"journal":{"name":"Neurology India","volume":"74 4","pages":"567-570"},"PeriodicalIF":0.8,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148536469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ultrasound-Guided Pulsed Radiofrequency of the Proximal Greater Occipital Nerve for Refractory Geniculate Neuralgia: A Case Series.","authors":"Suna Aşkın Turan, Derya Güner","doi":"10.4103/neurol-india.Neurol-India-D-26-00219","DOIUrl":"10.4103/neurol-india.Neurol-India-D-26-00219","url":null,"abstract":"","PeriodicalId":19429,"journal":{"name":"Neurology India","volume":"74 4","pages":"688-691"},"PeriodicalIF":0.8,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148536563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chorea Secondary to Subdural Hematoma.","authors":"Jamir Pitton Rissardo, Ana Letícia Fornari Caprara","doi":"10.4103/neurol-india.Neurol-India-D-25-00663","DOIUrl":"10.4103/neurol-india.Neurol-India-D-25-00663","url":null,"abstract":"","PeriodicalId":19429,"journal":{"name":"Neurology India","volume":"74 4","pages":"718-719"},"PeriodicalIF":0.8,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148536236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}