Neurology India最新文献

{"title":"Whether Air Pollution and Climate Change Actually Increase the Stroke Risk Requires Appropriately Designed Studies.","authors":"Josef Finsterer","doi":"10.4103/neurol-india.Neurol-India-D-26-00197","DOIUrl":"https://doi.org/10.4103/neurol-india.Neurol-India-D-26-00197","url":null,"abstract":"","PeriodicalId":19429,"journal":{"name":"Neurology India","volume":" ","pages":""},"PeriodicalIF":0.8,"publicationDate":"2026-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148983339","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"In Patients with Juvenile Myasthenia Gravis, the Search for Alternative Antibodies and the Application of Novel Therapies is Recommended.","authors":"Josef Finsterer","doi":"10.4103/neurol-india.Neurol-India-D-26-00329","DOIUrl":"https://doi.org/10.4103/neurol-india.Neurol-India-D-26-00329","url":null,"abstract":"","PeriodicalId":19429,"journal":{"name":"Neurology India","volume":" ","pages":""},"PeriodicalIF":0.8,"publicationDate":"2026-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148897647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"TASBAC Composite Score Predicts Neurological Improvement after Alteplase in Acute Ischemic Stroke.","authors":"Chaminda Kumara Udumulle Gedara, Janaka Peiris","doi":"10.4103/neurol-india.Neurol-India-D-25-00985","DOIUrl":"10.4103/neurol-india.Neurol-India-D-25-00985","url":null,"abstract":"<p><strong>Background: </strong>Time to treatment, baseline stroke severity, blood pressure, age, atrial fibrillation, and imaging findings are known determinants of outcome after thrombolysis. Their combined effect has not been well quantified.</p><p><strong>Methods: </strong>We conducted a cross-sectional study of 150 acute ischemic stroke patients treated with intravenous alteplase. We developed the TASBAC score (Time + Age + Stroke Severity + Blood Pressure + Atrial fibrillation + CT findings). Neurological improvement was defined as the change in NIHSS (NIHSSDIF) within 72 hours post treatment. Nonparametric (Spearman) and parametric (Pearson) correlations were used; significance was set at P < 0.05.</p><p><strong>Results: </strong>The mean age was 62.7 ± 10.4 years; 57.3% were male. Onset-to-needle time, door-to-needle time, baseline NIHSS, and diastolic BP were negatively correlated with NIHSSDIF (r s = -0.202, P = 0.013; -0.438, P < 0.001; -0.464, P < 0.001; -0.477, P < 0.001, respectively). Dense MCA sign was associated with lower NIHSS improvement (mean 0.04 vs. 2.09). TASBAC score showed a strong negative correlation with NIHSS improvement (r = -0.761, P < 0.001).</p><p><strong>Conclusions: </strong>TASBAC quantifies cumulative risk and robustly predicts early neurological recovery after thrombolysis. It may help in clinical stratification and decision-making.</p>","PeriodicalId":19429,"journal":{"name":"Neurology India","volume":" ","pages":"840-843"},"PeriodicalIF":0.8,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148897302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Umbrella Sign: Magnetic Resonance Imaging Marker of Central Brainstem Herniation in Hypoxic-Ischemic Encephalopathy.","authors":"Rishu Bansal, Atma Ram Bansal, Arun Garg, Tanu Singh","doi":"10.4103/neurol-india.Neurol-India-D-26-00159","DOIUrl":"10.4103/neurol-india.Neurol-India-D-26-00159","url":null,"abstract":"","PeriodicalId":19429,"journal":{"name":"Neurology India","volume":" ","pages":"951-952"},"PeriodicalIF":0.8,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148897488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Value of Anterior Petrosectomy During an Interdural, Trans-Meckel's Cave Approach to Dumbbell-Shaped Trigeminal Schwannoma.","authors":"Swarjith Nimmakayala, Kuntal K Das, Chandana Kanuru, Kamlesh S Bhaisora, Ved P Maurya, Ashutosh Kumar, Arun K Srivastava","doi":"10.4103/neurol-india.Neurol-India-D-26-00204","DOIUrl":"10.4103/neurol-india.Neurol-India-D-26-00204","url":null,"abstract":"<p><strong>Abstract: </strong>A detailed understanding of the dural anatomy of the trigeminal nerve, particularly the Meckel's cave, and the petrous apex is essential to accomplish an interdural approach in dumbbell-shaped trigeminal schwannomas (TSs) from the middle fossa side. A 34-year-old gentleman with left hemifacial pain and masseter weakness on examination was found to have a dumbbell-shaped TS around the petrous apex occupying the adjacent middle cranial fossa, posterior fossa, and the cavernous sinus. We performed an extended middle fossa approach (EMFA), taking an interdural route, and with the addition of an extradural anterior petrosectomy (AP), the tumor was completely resected. Postoperative imaging revealed a complete tumor excision, and the patient has been doing well at follow-up examinations. An EMFA with tailored AP provides an excellent control of the posterior fossa component of TS due to improved angulation and blind spot visualization.</p>","PeriodicalId":19429,"journal":{"name":"Neurology India","volume":" ","pages":"803-806"},"PeriodicalIF":0.8,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148897555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Early-Onset Epilepsy with Developmental Delay - A Novel C.1640A>C Mutation in the SETD1A Gene with Sensorineural Hearing Loss.","authors":"Uk Kandha Kumar, Pradeep Kumar Gunasekaran, Rahul Gupta, Kuldeep Singh, Lokesh Saini","doi":"10.4103/neurol-india.Neurol-India-D-25-00876","DOIUrl":"10.4103/neurol-india.Neurol-India-D-25-00876","url":null,"abstract":"","PeriodicalId":19429,"journal":{"name":"Neurology India","volume":" ","pages":"912-913"},"PeriodicalIF":0.8,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148897679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Safe Resection of Sciatic Neuroma and Reconstruction of the Tibial and Common Peroneal Nerves Using Autologous Sural Nerve Graft: Operative Video.","authors":"Rahul Ray, Sreekanth Velpula, Amol Raheja","doi":"10.4103/neurol-india.Neurol-India-D-26-00161","DOIUrl":"10.4103/neurol-india.Neurol-India-D-26-00161","url":null,"abstract":"<p><strong>Abstract: </strong>Sciatic nerve injuries result in profound motor and sensory deficits, and when direct repair is not feasible, autologous sural nerve grafting remains the gold standard for reconstruction. In this context, distal sciatic neuroma excision followed by sural nerve autografting illustrates the surgical nuances and technical challenges of bridging large distal nerve gaps. The procedure involves careful neuroma excision and reconstruction of the tibial and peroneal divisions using multiple reversed sural nerve cable grafts, with tension-free epineural coaptation performed under magnification to optimize outcomes. Although long grafts are associated with limited recovery, meticulous microsurgical technique and prioritization of the tibial division can enable meaningful functional restoration. Thus, autologous sural nerve grafting continues to provide a practical and viable solution for complex sciatic defects, underscoring its role in challenging reconstructions.</p>","PeriodicalId":19429,"journal":{"name":"Neurology India","volume":" ","pages":"807-810"},"PeriodicalIF":0.8,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148897835","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Two Anatomical Vantage Points, One Vision.","authors":"Ashutosh Carpenter, Prakash Nair","doi":"10.4103/neurol-india.neurol-india_12_26","DOIUrl":"https://doi.org/10.4103/neurol-india.neurol-india_12_26","url":null,"abstract":"","PeriodicalId":19429,"journal":{"name":"Neurology India","volume":"74 5","pages":"769-770"},"PeriodicalIF":0.8,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148963663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Craniotomy versus Endoscopic Membranectomy in the Treatment of Non-Homogeneous Chronic Subdural Hematoma: A Pilot Randomized Parallel-Group Active-Controlled Trial (EMiT CSDH 2).","authors":"K P Priyadharshan, M Kodeeswaran, S Prasad","doi":"10.4103/neurol-india.Neurol-India-D-25-00844","DOIUrl":"10.4103/neurol-india.Neurol-India-D-25-00844","url":null,"abstract":"<p><strong>Background: </strong>Chronic subdural hematoma (CSDH) is a prevalent neurosurgical condition with persistent challenges related to recurrence. Endoscopic membranectomy (EM) has shown promising results in managing symptomatic non-homogenous (SNH)-CSDH, but comparative evidence against craniotomy with membranectomy (CM) is lacking.</p><p><strong>Objectives: </strong>To compare the safety and efficacy of EM versus CM in managing SNH-CSDH.</p><p><strong>Materials and methods: </strong>A pilot randomized parallel-group active-controlled open- labeled superiority trial from September 2023 to November 2024 at Government Kilpauk Medical College, Chennai, India. Sixty patients with SNH-CSDH were randomized into EM and CM groups. Recurrence was the primary outcome. Secondary outcomes included operative time, complications, radiological indices, pain, hospital stay, and functional recovery. All patients were followed for six months.</p><p><strong>Results: </strong>No recurrence was observed in either group at six months. Two CM patients required reoperation on postoperative day one ( P = 0.15). EM was associated with shorter operative time ( P = 0.02), lower incidence of post-operative subdural residual fluid ( P = 0.015), better early hematoma reduction/subdural space reduction index ( P = 0.008), midline shift/symmetry improvement index ( P = 0.001), and lesser surgical site swelling ( P < 0.001). All patients were ambulant and had a Glasgow coma scale (GCS) 15 at discharge and at six months (including reoperated patients). Pain scores and functional recovery were comparable. EM patients had shorter hospital stays ( P = 0.004) and no significant complications.</p><p><strong>Conclusion: </strong>EM demonstrated favorable early radiological outcomes, fewer complications, and comparable functional recovery and recurrence versus CM in SNH-CSDH. Independent reproduction and larger multicentric trials are needed for validity and generalizability.</p>","PeriodicalId":19429,"journal":{"name":"Neurology India","volume":" ","pages":"844-852"},"PeriodicalIF":0.8,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148796208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Arterial Spin Labeling (ASL) Hyperperfusion in Wilson's Disease: When Copper Drives Inflammation, Not Seizures.","authors":"Jubin John, Smily Sharma, Adarsh A Kumar, M G Rohit, Ramshekhar N Menon, Chandrasekharan Kesavadas","doi":"10.4103/neurol-india.Neurol-India-D-25-01045","DOIUrl":"10.4103/neurol-india.Neurol-India-D-25-01045","url":null,"abstract":"","PeriodicalId":19429,"journal":{"name":"Neurology India","volume":" ","pages":"928-929"},"PeriodicalIF":0.8,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148897712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}