Neurology IndiaPub Date : 2026-05-01Epub Date: 2026-05-06DOI: 10.4103/neurol-india.Neurol-India-D-25-00598
Saraj K Singh, Kranti Bhavana, Arun Srinivaasan, Govind S Bhuskute
{"title":"Surgical Nuances of Managing Sinonasal Malignancy by Endoscopic Endonasal Transcribriform Approach.","authors":"Saraj K Singh, Kranti Bhavana, Arun Srinivaasan, Govind S Bhuskute","doi":"10.4103/neurol-india.Neurol-India-D-25-00598","DOIUrl":"https://doi.org/10.4103/neurol-india.Neurol-India-D-25-00598","url":null,"abstract":"<p><strong>Abstract: </strong>Sinonasal malignancies especially involving the ethmoidal sinuses, and nasal cavity can involve the cribriform plate and base of anterior cranial fossa. Endoscopic endonasal transcribriform approach gives a minimally invasive corridor to achieve a complete tumor removal with negative margins. To demonstrate the surgical techniques of endoscopic transcribriform approach to anterior cranial fossa in a case of adenoid cystic carcinoma of nose. Rapid debulking of tumor was performed on the right nasal cavity with removal of orbital portion of tumor, and complete excision of involved dura after an endoscopic craniectomy. This was followed by a multi-layered repair of the skull base defect. Transcribriform approach is a minimally invasive corridor to approach the sinonasal malignancies extending in the anterior cranial fossa and tumors of olfactory. Appropriate case selection is pertinent for considering a case of sinonasal malignancy for endoscopic endonasal transcribriform approach. Involvement of external nasal skin and periorbita is a contraindication for an endoscopic approach.</p>","PeriodicalId":19429,"journal":{"name":"Neurology India","volume":"74 3","pages":"399-402"},"PeriodicalIF":0.8,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147840249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Neurology IndiaPub Date : 2026-05-01Epub Date: 2026-05-06DOI: 10.4103/neurol-india.Neurol-India-D-25-00915
Laisson de Moura Feitoza, Leonardo de Deus Silva, Fabiano Reis
{"title":"Acute Subdural Hematoma Secondary to Paraclinoid Internal Carotid Aneurysm with Rebleeding following Angiography.","authors":"Laisson de Moura Feitoza, Leonardo de Deus Silva, Fabiano Reis","doi":"10.4103/neurol-india.Neurol-India-D-25-00915","DOIUrl":"https://doi.org/10.4103/neurol-india.Neurol-India-D-25-00915","url":null,"abstract":"","PeriodicalId":19429,"journal":{"name":"Neurology India","volume":"74 3","pages":"544-545"},"PeriodicalIF":0.8,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147841086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Neurology IndiaPub Date : 2026-05-01Epub Date: 2026-05-06DOI: 10.4103/neurol-india.Neurol-India-D-25-00833
Jitin Bajaj, Amar Pratap, Diya Bajaj, Jayant Patidar, Mukesh Sharma, Mallika Sinha, Shailendra Ratre, Vijay S Parihar, Yad R Yadav
{"title":"Endoscopic Transorbital Excision of an Intraconal Hemangioma.","authors":"Jitin Bajaj, Amar Pratap, Diya Bajaj, Jayant Patidar, Mukesh Sharma, Mallika Sinha, Shailendra Ratre, Vijay S Parihar, Yad R Yadav","doi":"10.4103/neurol-india.Neurol-India-D-25-00833","DOIUrl":"https://doi.org/10.4103/neurol-india.Neurol-India-D-25-00833","url":null,"abstract":"<p><strong>Abstract: </strong>Intraconal orbital tumors require a surgical approach tailored to their relationship with the optic nerve. Endoscopic transorbital surgery offers a minimally invasive corridor for lesions located lateral to the nerve. It avoids the morbidity of traditional cranio-orbital approaches. We present a step-by-step operative video of excision of an intraconal cavernous hemangioma through the endoscopic transorbital approach in a 55-year-old man with progressive left-eye proptosis and facial pain. Under endoscopic visualization, through a lateral canthal incision, the lateral canthal tendon and crura were divided, the periorbita opened, and the tumor dissected and removed en bloc without orbital bone drilling. Postoperative vision and extraocular movements were preserved. This case demonstrates step-by-step operative nuances of the safety and efficacy of the endoscopic transorbital route for appropriately selected intraconal lesions.Pearls and Pitfalls:Review detailed orbital anatomy and preoperative imaging. Protect the globe with a moist shield throughout the procedure. Adequately release the lateral canthal tendon to create a proper corridor, and retract it using stay sutures. Use 0°/30° endoscopes and perform gentle, circumferential dissection. One should strive to preserve the orbital fat and prefer its retraction to prevent postoperative fibrosis and enophthalmos. Excision of fat should be as minimal as possible. Avoid lesions medial to or crossing the optic nerve-these are contraindications. Ensure good visualization; poor exposure increases the risk of injury. Handle the optic nerve and extraocular muscles with extreme care to prevent deficits. Avoid unnecessary bone drilling. Be cautious with large vascular tumors; piecemeal removal can increase bleeding and risk incomplete excision.</p>","PeriodicalId":19429,"journal":{"name":"Neurology India","volume":"74 3","pages":"403-406"},"PeriodicalIF":0.8,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147841100","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Neurology IndiaPub Date : 2026-05-01Epub Date: 2026-05-06DOI: 10.4103/neurol-india.Neurol-India-D-25-00548
Sreekanth Velpula, Pushpendu Chakraborty, Kaashvi Gupta, Ravi H Phulware, Saravanan Sadhasivam
{"title":"An Unusual Location and Association of Primary Extra-Renal Wilms' Tumor with Spinal Dysraphism.","authors":"Sreekanth Velpula, Pushpendu Chakraborty, Kaashvi Gupta, Ravi H Phulware, Saravanan Sadhasivam","doi":"10.4103/neurol-india.Neurol-India-D-25-00548","DOIUrl":"https://doi.org/10.4103/neurol-india.Neurol-India-D-25-00548","url":null,"abstract":"","PeriodicalId":19429,"journal":{"name":"Neurology India","volume":"74 3","pages":"498-501"},"PeriodicalIF":0.8,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147841110","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Neurology IndiaPub Date : 2026-05-01Epub Date: 2026-05-06DOI: 10.4103/neurol-india.Neurol-India-D-25-00444
Anand Raksha, Kamath Sriganesh, Ganjigere Palaksha Deepak, Konar Subhas
{"title":"Anesthetic Management of a Child with Hydrocephalic Macrocephaly for Reduction Cranioplasty Surgery.","authors":"Anand Raksha, Kamath Sriganesh, Ganjigere Palaksha Deepak, Konar Subhas","doi":"10.4103/neurol-india.Neurol-India-D-25-00444","DOIUrl":"https://doi.org/10.4103/neurol-india.Neurol-India-D-25-00444","url":null,"abstract":"","PeriodicalId":19429,"journal":{"name":"Neurology India","volume":"74 3","pages":"495-497"},"PeriodicalIF":0.8,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147841140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Surgical Management of Giant Cervico-Dorsal Aneurysmal Bone Cyst: Case Report with Literature-Review.","authors":"Sivaraman Kumarasamy, Satish Kumar Verma, Pankaj Kumar Singh, Poodipedi Sarat Chandra, Shashank Sharad Kale","doi":"10.4103/neurol-india.Neurol-India-D-24-00626","DOIUrl":"https://doi.org/10.4103/neurol-india.Neurol-India-D-24-00626","url":null,"abstract":"<p><strong>Abstract: </strong>Aneurysmal bone cysts (ABC) are benign, vascular, osseous lesions accounting for 1% of all bony tumors. Giant cervicodorsal ABC are rare. Surgical excision is the treatment of choice. Incomplete excision has a high chance of recurrence. Giant lesions of the spinal column require staged surgeries and circumferential instrumentation to avoid instability. An 18-year-old male presenting with acute onset paraplegia and urinary incontinence with features of myelopathy. On evaluation, he was diagnosed with multi-level giant ABC of the cervico-dorsal spine. He underwent tumor excision and instrumentation via staged surgery. The postoperative course was uneventful. The patient was planned for adjuvant therapy but lost to follow up. He developed torrential bleeding from the tracheostomy site and expired. Management of giant ABC poses a challenge to the neurosurgeon. Multidisciplinary approach is mandatory for successful management of these patients. Surgical excision is the treatment of choice. Complete excision is achievable using staged excision.</p>","PeriodicalId":19429,"journal":{"name":"Neurology India","volume":"74 3","pages":"480-485"},"PeriodicalIF":0.8,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147841175","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Neurology IndiaPub Date : 2026-05-01Epub Date: 2026-05-06DOI: 10.4103/neurol-india.Neurol-India-D-25-00733
Debabrata Chakraborty
{"title":"Might We Consider Placing More Emphasis on the Relationship Between Autonomic Dysfunction and Stroke?","authors":"Debabrata Chakraborty","doi":"10.4103/neurol-india.Neurol-India-D-25-00733","DOIUrl":"https://doi.org/10.4103/neurol-india.Neurol-India-D-25-00733","url":null,"abstract":"","PeriodicalId":19429,"journal":{"name":"Neurology India","volume":"74 3","pages":"542-543"},"PeriodicalIF":0.8,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147841190","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Neurology IndiaPub Date : 2026-05-01Epub Date: 2026-05-06DOI: 10.4103/neurol-india.Neurol-India-D-25-00097
Sonali Mishra, Saurabh Kumar Gautam, Bibek Keshari, Amber Prasad, Nishant Goyal, Ravi Hari Phulware
{"title":"Cerebral Chromoblastomycosis: A Clinico-Pathological Feature of a Single Case.","authors":"Sonali Mishra, Saurabh Kumar Gautam, Bibek Keshari, Amber Prasad, Nishant Goyal, Ravi Hari Phulware","doi":"10.4103/neurol-india.Neurol-India-D-25-00097","DOIUrl":"https://doi.org/10.4103/neurol-india.Neurol-India-D-25-00097","url":null,"abstract":"","PeriodicalId":19429,"journal":{"name":"Neurology India","volume":"74 3","pages":"522-525"},"PeriodicalIF":0.8,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147841063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Neurology IndiaPub Date : 2026-05-01Epub Date: 2026-05-06DOI: 10.4103/neurol-india.Neurol-India-D-25-00950
Bibesh Pokhrel, Amit Thapa
{"title":"Intravenous Tranexamic Acid in Primary Intracerebral Hemorrhage Trial: A Phase 2 Randomized Control Trial.","authors":"Bibesh Pokhrel, Amit Thapa","doi":"10.4103/neurol-india.Neurol-India-D-25-00950","DOIUrl":"https://doi.org/10.4103/neurol-india.Neurol-India-D-25-00950","url":null,"abstract":"<p><strong>Background: </strong>In low- and middle-income countries (LMICs) where neurosurgical access is limited, early nonsurgical medical interventions in primary intracerebral hemorrhage (ICH) has potential benefits. This study assesses the efficacy of early intravenous tranexamic acid (TXA), in reducing expansion of hematoma and improving long-term outcomes in ICH patients.</p><p><strong>Methods: </strong>We conducted a phase 2, randomized, double-blind, placebo-controlled trial. Besides controlling blood pressure, patients with primary ICH presenting within 24 hours were randomly assigned to receive either 1g intravenous TXA or a placebo. The primary outcome was hematoma size change at 48 hours. Secondary outcomes included neurological recovery, survival, healthcare utilization, and complications. Data were analyzed on an intention-to-treat basis.</p><p><strong>Results: </strong>A total of 154 patients were enrolled, with 78 in the TXA group. At 48 hours, the TXA group had a mean reduction in hematoma size of -0.434 ± 2.23 mL, while the placebo group exhibited increase of 0.462 ± 3.02 mL (P = 0.038). Nonprogression of hematoma occurred in 58.1% of the TXA group versus 43.7% in the placebo group (NNT = 7). Mortality at 180 days was significantly lower in the TXA group (25.6%) compared with the placebo group (38.2%, P = 0.047). Surgical intervention rates were also lower in the TXA group (15.4% vs. 26.3%, P = 0.048). No adverse events related to TXA were reported.</p><p><strong>Conclusion: </strong>Intravenous TXA administered within 24 hours reduced hematoma progression, mortality, and surgical intervention in primary ICH. These findings support its safety and potential benefit, particularly in LMICs, pending confirmation in larger trials.</p>","PeriodicalId":19429,"journal":{"name":"Neurology India","volume":"74 3","pages":"411-417"},"PeriodicalIF":0.8,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147841085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}