Neurology India最新文献_第2页

Gadolinium Deposition in the Rat Brain after Repeated Administration of the Liver-Specific Gadolinium-Based Contrast Agent Gadoxetic Acid. 肝特异性钆造影剂加多乙酸对大鼠脑内钆沉积的影响。

IF 0.9 3区医学

Neurology India Pub Date : 2025-05-01 Epub Date: 2025-05-23 DOI: 10.4103/NI.NI_776_20

Kai Zhu, Yikai Xu

{"title":"Gadolinium Deposition in the Rat Brain after Repeated Administration of the Liver-Specific Gadolinium-Based Contrast Agent Gadoxetic Acid.","authors":"Kai Zhu, Yikai Xu","doi":"10.4103/NI.NI_776_20","DOIUrl":"https://doi.org/10.4103/NI.NI_776_20","url":null,"abstract":"Background: Studies on gadolinium deposition have recently been reported.Objective: The objective of this study was to investigate whether there is an increased magnetic resonance signal intensity (SI) of the dentate nucleus (DCN) and quantification of gadolinium (Gd) brain concentrations by inductively coupled plasma-mass spectrometry (ICP-MS) test in rats who had undergone multiple administrations of gadoxetic acid and gadobutrol.Materials and methods: Sprague-Dawley rats (24) were equally divided into three groups. Eight animals per group received 20 intravenous injections of gadoxetic acid (0.15 mmol/kg) and gadobutrol (0.6 mmol/kg) per injection. MRI was performed at 0, 5, and 20 weeks. Subsequently, all animals were euthanized and their brains were dissected for Gd quantification by ICP-MS.Results: ICP-MS revealed higher Gd content in cerebellum tissue after administration of gadoxetic acid compared to gadobutrol (P < 0.05). The mean Gd concentrations in the cerebellum were 0.48 nmol/g gadoxetic acid and 0.26 nmol/g gadobutrol after intravenous administration. No visually evident enhancement was found after administration of gadoxetic acid, gadobutrol, or saline at any time point. The DCN-to-pons SI ratios for gadoxetic acid and gadobutrol were not different from the saline control group (P > 0.05, saline vs. gadoxetic acid and saline vs. gadobutrol, respectively).Conclusions: Our results demonstrated that gadolinium concentrations in the cerebellum after intravenous gadoxetic acid administration were higher than for gadobutrol. Multiple administrations of gadoxetic acid disodium are not associated with increased SI in DCN.","PeriodicalId":19429,"journal":{"name":"Neurology India","volume":"73 3","pages":"495-499"},"PeriodicalIF":0.9,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144132679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Craniospinal Hypotension - An Unusual Cause for Fluctuating Sensorium after Aneurysm Clipping. 颅脊髓低血压-动脉瘤夹闭后感觉波动的不寻常原因。

IF 0.9 3区医学

Neurology India Pub Date : 2025-05-01 Epub Date: 2024-11-29 DOI: 10.4103/ni.ni_621_21

Ishaan Suniara, Karen R Lionel, Georgene Singh, Baylis V Joseph

引用次数: 0

Extended Laminectomy in Chiari Malformation Treatment: A Systematic Review. 扩展椎板切除术治疗Chiari畸形：系统综述。

IF 0.9 3区医学

Neurology India Pub Date : 2025-05-01 Epub Date: 2025-05-23 DOI: 10.4103/neurol-india.Neurol-India-D-24-00117

Guilherme L O Lima, Fábio B R Silva, Daniel F F Paiva

{"title":"Extended Laminectomy in Chiari Malformation Treatment: A Systematic Review.","authors":"Guilherme L O Lima, Fábio B R Silva, Daniel F F Paiva","doi":"10.4103/neurol-india.Neurol-India-D-24-00117","DOIUrl":"https://doi.org/10.4103/neurol-india.Neurol-India-D-24-00117","url":null,"abstract":"Extended C2 laminectomy may expand the formation of the neocisterna magna in Chiari malformation (CM) surgery to improve cerebrospinal fluid (CSF) flow in the craniovertebral junction (CVJ). We aimed to clarify indications, outcomes, and complications of C2 laminectomy in CM. A systematic review (PROSPERO CRD42022340553) following the PRISMA protocol was performed in Pubmed, Web of Science, Cochrane, Embase, and Scopus databases with the Medical Subject Headings-based search strategy \"(\"Arnold-Chiari Malformation\") AND (\"Decompression, Surgical\" OR \"Axis, Cervical\") AND (Headache OR Vertigo OR \"Deglutition Disorders\")\". The endpoints were symptom improvement and complication rates. Thirteen original articles included were case reports or series. The extent of laminectomy was directly related to the degree of tonsillar herniation. Six studies presented the perception of improvement (Gestalt) range from 83% to 100%. Three articles applied objective scales to report improvement in headache (VAS) and strength (MRC or ASIA). Nine studies reported complication rates. Fistula occurred in a range of 2% to 9.5% of cases. Three articles presented data on multilevel laminectomy for CM, and five studies reported on pediatric cases. Spine deformity was observed in children after wide multilevel laminectomy. This review showed a few concerns about C2 laminectomy. The descent of tonsilar herniation was the parameter for removing C2 lamina with good global results and complication rates. C2 laminectomy can be performed in young patients without previous instability. However, the lack of stratification of cases and systematization of the evaluation of results compromised the comparative analysis of the usefulness of C2 laminectomy in treating CM.","PeriodicalId":19429,"journal":{"name":"Neurology India","volume":"73 3","pages":"415-422"},"PeriodicalIF":0.9,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144132677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Postoperative Hyperglycemia with Ketosis Sans Acidemia in a Child Immediately Following Fourth Ventricular Medulloblastoma Resection: Anesthetic Concerns and Intensive Care Management. 第四脑室髓母细胞瘤切除术后立即发生高血糖伴酮症无酸血症的儿童：麻醉问题和重症监护管理。

IF 0.9 3区医学

Neurology India Pub Date : 2025-05-01 Epub Date: 2025-05-23 DOI: 10.4103/neurol-india.Neurol-India-D-24-00159

Arvin Ahuja, Ranganatha Praveen, Manikandan Sethuraman, Ajay P Hrishi, Jeeva George

引用次数: 0

Bannwarth's Syndrome - Meningoradiculoneuritis Due to European Neuroborreliosis in Kerala. Bannwarth综合征-由欧洲喀拉拉邦神经螺旋体病引起的脑膜根状神经炎。

IF 0.9 3区医学

Neurology India Pub Date : 2025-05-01 Epub Date: 2024-11-29 DOI: 10.4103/ni.ni_1840_20

Boby Varkey Maramattom, Anup Warrier

引用次数: 0

Adult-Onset Leucoencephalopathy with Axonal Spheroids and Pigmented Glia: Report of Two Cases. 成人发病伴轴突球体和色素胶质的白质脑病：附2例报告。

IF 0.9 3区医学

Neurology India Pub Date : 2025-05-01 Epub Date: 2024-11-29 DOI: 10.4103/ni.ni_376_22

Sharath Kumar Goddu Govindappa, Chaitra Parameshwara Adiga, Lakshmikanth N Goolahally, P Prakash

引用次数: 0

Bibliometrics and Visualization Analysis of Neuromuscular Junction Model. 神经肌肉连接模型的文献计量学与可视化分析。

IF 0.9 3区医学

Neurology India Pub Date : 2025-05-01 Epub Date: 2025-05-23 DOI: 10.4103/ni.ni_385_22

Xincheng Du, Wenwen Liu, Jin Geng, Haowen Qiao, Yu Zhou

{"title":"Bibliometrics and Visualization Analysis of Neuromuscular Junction Model.","authors":"Xincheng Du, Wenwen Liu, Jin Geng, Haowen Qiao, Yu Zhou","doi":"10.4103/ni.ni_385_22","DOIUrl":"https://doi.org/10.4103/ni.ni_385_22","url":null,"abstract":"Objective: Neuromuscular junctions, which are responsible for voluntary motor function, are the chemical synapses between motor neurons and skeletal muscle fibers. In this study, we performed a scientometric analysis that can be used to construct and visualize networks of neuromuscular junction model (NMJM) using bibliometric methods.Materials and methods: A literature survey for NMJM was conducted using \"TS= (neuromuscular junction model),\" including literature titles, abstracts, and keywords, under the Web of Science Core Collection (WoSCC). Document production was analyzed by document citation, source journals, authors, highly cited documents, countries, organizations, impact factors.Results: A total of 2046 articles published over the past two decades were retrieved and analyzed. Our results showed that the number of publications in NMJM has increased rapidly over the past 20 years. The most productive author in terms of total publications about NMJM was Thomas H. Gillingwater with 27 documents, who worked at the University of Miami. The geographic distribution of publications showed that majority of them were from the USA. In addition, the research hotspot of NMJM was expanding from the establishment of NMJM to mechanistic studies of diseases.Conclusions: This study provides a unique perspective for understanding the evaluative history and future trends of NMJM.","PeriodicalId":19429,"journal":{"name":"Neurology India","volume":"73 3","pages":"506-512"},"PeriodicalIF":0.9,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144132667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Expanding Phenotype of ATP1A3 Mutation. ATP1A3突变的扩展表型。

IF 0.9 3区医学

Neurology India Pub Date : 2025-05-01 Epub Date: 2024-11-29 DOI: 10.4103/ni.ni_1335_20

Ajith Cherian, J Nandana, K P Divya

引用次数: 0

IF 0.9 3区医学

Neurology India Pub Date : 2025-05-01 Epub Date: 2024-11-29 DOI: 10.4103/ni.ni_839_21

Madihah Faisal, Rajesh B Iyer, Javeria Nooraine, Sanjeev J Mudakavi, R Jaychandran, S Raghavendra

引用次数: 0

Normative Value of F-wave Minimum Latency in a Tertiary Care Center In Eastern India. 印度东部三级医疗中心f波最小潜伏期的规范值。

IF 0.9 3区医学

Neurology India Pub Date : 2025-05-01 Epub Date: 2025-05-23 DOI: 10.4103/ni.ni_491_21

Alak Pandit, Srimant Pattnaik, Samar Biswas, Bijaya N Naik

{"title":"Normative Value of F-wave Minimum Latency in a Tertiary Care Center In Eastern India.","authors":"Alak Pandit, Srimant Pattnaik, Samar Biswas, Bijaya N Naik","doi":"10.4103/ni.ni_491_21","DOIUrl":"https://doi.org/10.4103/ni.ni_491_21","url":null,"abstract":"Background: F-wave normative values may be country- or geographic locality-specific, as shown in various studies. Hence, using the same cut-off value in all laboratories leads to errors. This study attempts to determine the normative value of the F-wave in eastern India.Objective: This study aims to find normative data on F-wave minimum latency in a healthy population in Eastern India and to check the correlation of F-wave minimum latency with height, age, and sex.Methods: Healthy volunteers aged 18-45 participated in the nerve conduction study to determine F-wave minimum latency in the bilateral median, ulnar, and tibial nerves. The height of the volunteers was recorded. This is a descriptive cross-sectional study.Results: A total of 150 healthy volunteers participated (70 females, 80 males). The mean age of the study population was 30.7 ± 8.4 years. The mean height of the participants was 160.5 ± 9.0 cm. The mean values of F-wave minimum latencies are as follows: 24.85 ± 1.87 msec for the median nerve, 25.1 ± 2.01 msec for the ulnar nerve, and 45.56 ± 3.74 msec for the tibial nerve. The most significant effect on latency was by height.Conclusions: The cut-off value for F-wave minimal latency may be kept as follows: right median nerve: 28.57 msec, left median nerve: 28.58 msec, left ulnar nerve: 29.24 msec, right ulnar nerve: 29.01 msec, left tibial nerve: 53.21 msec, and right tibial nerve: 52.85 msec.","PeriodicalId":19429,"journal":{"name":"Neurology India","volume":"73 3","pages":"469-473"},"PeriodicalIF":0.9,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144132691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0