Neurology India最新文献_第9页

Olfactory Evoked Potential Monitoring: Technical Note and Challenges Faced. 嗅觉诱发电位监测：技术说明和面临的挑战。

IF 0.9 3区医学

Neurology India Pub Date : 2024-11-01 Epub Date: 2024-12-17 DOI: 10.4103/ni.ni_532_22

Bujji Karre, Gopalakrishnan M Sasidharan

{"title":"Olfactory Evoked Potential Monitoring: Technical Note and Challenges Faced.","authors":"Bujji Karre, Gopalakrishnan M Sasidharan","doi":"10.4103/ni.ni_532_22","DOIUrl":"10.4103/ni.ni_532_22","url":null,"abstract":"Background and aim: Despite the sustained progress in the realm of intraoperative neurophysiologic monitoring of the nervous system, little progress has been achieved in monitoring the olfactory pathway. Loss of olfactory function due to retraction-induced physical damage during operations has ill-appreciated negative consequences for the patients and is often underreported. Improvements in this area of neuromonitoring require a revisit of the technical challenges. We aim to describe the method to construct flexible, bipolar silver ball electrodes to stimulate the olfactory mucosa during cranial neurosurgery and suggest ways to overcome the challenges in eliciting olfactory evoked potentials.Materials and methods: We analyze the potential difficulties in routinely eliciting olfactory evoked potential in neurosurgical operations and summarize ways to overcome them. We also describe the construction of a simple electrical stimulator electrode for the olfactory mucosa, its application, and potential recording sites in an effort to detect the potential during cranial neurosurgery.Results: We created flexible, insulated bipolar silver electrodes and placed them atraumatically on the olfactory mucosa under endoscopic guidance, bilaterally, in 22 patients. We obtained an optimal position in less than 10 minutes in most cases. We also summarize the challenges faced and potential paths to overcome them.Conclusions: Though electrical stimulation of the olfactory mucosa using custom-made silver electrodes is possible and takes little time to place them as part of an intraoperative neurophysiologic monitoring setup, detecting the minute potential remains elusive.","PeriodicalId":19429,"journal":{"name":"Neurology India","volume":"72 6","pages":"1237-1240"},"PeriodicalIF":0.9,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142847269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Role of Nonsteroidal Anti-Inflammatory Drugs as a Protective Factor in Alzheimer's Disease: A Systematic Review and Meta-Analysis. 非甾体抗炎药作为阿尔茨海默病保护因素的作用：系统综述和荟萃分析

IF 0.9 3区医学

Neurology India Pub Date : 2024-11-01 Epub Date: 2024-12-17 DOI: 10.4103/ni.ni_1073_22

Akash Asthana, Shashank Tripathi, Rachna Agarwal

{"title":"Role of Nonsteroidal Anti-Inflammatory Drugs as a Protective Factor in Alzheimer's Disease: A Systematic Review and Meta-Analysis.","authors":"Akash Asthana, Shashank Tripathi, Rachna Agarwal","doi":"10.4103/ni.ni_1073_22","DOIUrl":"10.4103/ni.ni_1073_22","url":null,"abstract":"Alzheimer's disease (AD) is a major neurodegenerative disease, affecting more than two-third cases of dementia in the world. Nonsteroidal anti-inflammatory drugs (NSAIDs) are widely used anti-inflammatory analgesic agents, representing 7.7% of worldwide prescriptions, of which 90% are in patients over 65 years old. Based on mixed findings by different randomized clinical trials (RCTs), a systematic review and meta-analysis were conducted to develop a better understanding of the protective role of NSAIDs in AD. Database search was Pubmed, WebScience, and Embase. RCTs investigating the effect of NSAIDs on AD or test scores assessing cognitive function in people without AD at baseline were included. Two indicators were the Mini-Mental State Examination (MMSE) Score and Hazard Ratio. 09 studies were included in the present Meta-analysis. For the MMSE score difference, the pooled effect size was - 0.06 (-0.22, 0.10) which was not statistically significant (P value = 0.47). For the MMSE score, the pooled effect size was - 0.0036(-0.0320, 0.0248), which was also not statistically significant (P value = 0.87). For Hazard Ratio (HR), the pooled HR calculated using the random effect model was 1.20 (95% CI: 0.95, 1.51), which was not statistically significant (P value = 0.15). Present meta-analysis shows that NSAIDs, in general, are not effective in the treatment of AD. They also have no protective effect against the development of AD on their sustained use.","PeriodicalId":19429,"journal":{"name":"Neurology India","volume":"72 6","pages":"1144-1151"},"PeriodicalIF":0.9,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142847297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Case Series in a Tertiary Care Headache Center: Ultrasound-Guided Proximal Greater Occipital Nerve Pulsed Radiofrequency is Effective in Migraine with Aura for Six Months. 一家三级头痛治疗中心的病例系列：超声引导下的大枕神经近端脉冲射频治疗先兆偏头痛疗效显著，可持续六个月。

IF 0.9 3区医学

Neurology India Pub Date : 2024-11-01 Epub Date: 2024-12-17 DOI: 10.4103/neurol-india.Neurol-India-D-24-00654

Suna Aşkın Turan, Şenay Aydın

引用次数: 0

A Rare Case of Coexistence between Epidermoid Cyst and Meningioma in Cerebellopontine Angle Manifesting as Trigeminal Neuralgia. 小脑脑角表皮样囊肿与脑膜瘤并存并表现为三叉神经痛的罕见病例

IF 0.9 3区医学

Neurology India Pub Date : 2024-11-01 Epub Date: 2024-12-17 DOI: 10.4103/neurol-india.Neurol-India-D-24-00265

Wang Hongzhang, Zhang Xiaobiao, Sun Chongjing

引用次数: 0

Erratum: Diagnostic Dilemma between Scrub Typhus Meningoencephalitis and Dengue Encephalopathy Resolved! - A Novel Prediction Score. 勘误：丛林斑疹伤寒脑膜脑炎和登革热脑病的诊断困境解决！-一个新颖的预测分数。

IF 0.9 3区医学

Neurology India Pub Date : 2024-11-01 Epub Date: 2024-12-17 DOI: 10.4103/neurol-india.neurol-india_99_24

引用次数: 0

Sprengel Deformity with Bilateral Omovertebral Bars in Klippel-Feil Syndrome. Klippel-Feil综合征伴双侧大椎弓根的Sprengel畸形。

IF 0.9 3区医学

Neurology India Pub Date : 2024-11-01 Epub Date: 2024-12-17 DOI: 10.4103/neurol-india.Neurol-India-D-24-00317

Shruthi M Maivizhi, Sahoo Biswajit, Manoj Kumar Nayak

引用次数: 0

Uncommon Manifestation of a Common Disease: Neurogenic Claudication Secondary to Epidural Spillage of Vertebral Hemangioma. 一种常见疾病的不常见表现：椎体血管瘤硬膜外渗漏继发神经源性跛行。

IF 0.9 3区医学

Neurology India Pub Date : 2024-11-01 Epub Date: 2024-12-17 DOI: 10.4103/neurol-india.Neurol-India-D-24-00546

Anish Kosanam, Varunil Shah, Manish K Kasliwal

引用次数: 0

Coiling of a Bihemispheric ACA Aneurysm Associated with Contralateral Persistent Primitive Olfactory Artery. 卷曲伴有对侧持续性原始嗅动脉的双半球 ACA 动脉瘤。

IF 0.9 3区医学

Neurology India Pub Date : 2024-11-01 Epub Date: 2024-12-17 DOI: 10.4103/neurol-india.Neurol-India-D-24-00519

Arpan Dutta, Subhadeep Gupta, Uddalak Chakraborty, Deep Das, Biman Kanti Ray

引用次数: 0

Assessment of White Matter Alterations in Patients of Migraine Using Diffusion Tensor Imaging. 弥散张量成像评估偏头痛患者白质改变。

IF 0.9 3区医学

Neurology India Pub Date : 2024-11-01 Epub Date: 2024-12-17 DOI: 10.4103/ni.ni_894_22

Civilee Nanda, Namrita Sachdev

{"title":"Assessment of White Matter Alterations in Patients of Migraine Using Diffusion Tensor Imaging.","authors":"Civilee Nanda, Namrita Sachdev","doi":"10.4103/ni.ni_894_22","DOIUrl":"10.4103/ni.ni_894_22","url":null,"abstract":"Background: Vascular hypotheses was previously considered to play a major role in pathophysiology of migraine. Recently, neurological mechanisms have been proposed with implication of the trigemino-vascular pathway. Deciphering the pathophysiology of this disorder is extremely important for diagnosis, assessment of progression and to explore targeted treatment options.Objectives: To assess white matter alterations in patients of migraine by using Diffusion Tensor Imaging.Materials and methods: We performed Diffusion Tensor Imaging in migraine patients to assess changes in microstructural integrity of white matter tracts involved in pain processing to localize the tracts involved in migraine. This is a cross-sectional observational study involving 50 subjects (30 patients of migraine diagnosed as per ICHD-III and 20 age and sex matched controls). DTI was performed on 3T MRI and the mean diffusivity and fractional anisotropy values of the cases were compared with controls.Results and conslusion: Significant changes were noted in the multiple white matter tracts implicated in pain processing compared to the controls. Significant association was also noted between the DTI parameters and the type and frequency of migraine. DTI can thus assist in the diagnosis, assessing the extent of neurological damage in patients of migraine and follow up post treatment.","PeriodicalId":19429,"journal":{"name":"Neurology India","volume":"72 6","pages":"1169-1173"},"PeriodicalIF":0.9,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142847157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Diffuse Leptomeningeal Glioneuronal Tumor: A Rare Clinico-radiological Masquerade. 弥漫性轻脑膜胶质细胞肿瘤：罕见的临床-放射伪装。

IF 0.9 3区医学

Neurology India Pub Date : 2024-11-01 Epub Date: 2024-12-17 DOI: 10.4103/neurol-india.Neurol-India-D-23-00651

Charu Paruthi, Rohini Gupta Ghasi, Rachna Sehgal, Amitabh Singh

引用次数: 0