Neurology India最新文献

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Birds of a Feather Flock Together! A Rare Case of Sporadic Inclusion Body Myositis and Rheumatoid Arthritis Treated with Rituximab. 物以类聚,人以群分利妥昔单抗治疗散发性包涵体肌炎合并类风湿关节炎1例。
IF 0.8 3区 医学
Neurology India Pub Date : 2026-09-01 Epub Date: 2026-09-08 DOI: 10.4103/neurol-india.Neurol-India-D-25-00704
Sayooja Sachithanandan, Rajalakshmi Poyuran, Sruthi S Nair, Asish Vijayaraghavan
{"title":"Birds of a Feather Flock Together! A Rare Case of Sporadic Inclusion Body Myositis and Rheumatoid Arthritis Treated with Rituximab.","authors":"Sayooja Sachithanandan, Rajalakshmi Poyuran, Sruthi S Nair, Asish Vijayaraghavan","doi":"10.4103/neurol-india.Neurol-India-D-25-00704","DOIUrl":"10.4103/neurol-india.Neurol-India-D-25-00704","url":null,"abstract":"<p><strong>Abstract: </strong>Inclusion body myositis (IBM) is considered an inflammatory myopathy with a degenerative counterpart that is generally refractory to standard immunotherapy. We describe the case of a 47-year-old lady who had a long history of rheumatoid arthritis (RA) and subsequently developed weakness in her limbs. A muscle biopsy revealed typical features of IBM along with vasculitis. She was initiated on pulse corticosteroids followed by rituximab. The patient made a steady and marked recovery in both muscle weakness and inflammatory arthritis. Rare cases of IBM in patients with RA with favorable responses to immunotherapy have been reported before. This case demonstrates the importance of identifying coexisting autoimmune disorders and executing a long-term immunomodulatory plan.</p>","PeriodicalId":19429,"journal":{"name":"Neurology India","volume":" ","pages":"904-907"},"PeriodicalIF":0.8,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148906883","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Agony and the Ecstasy: Refining Surgical Decision-Making in Trigeminal Neuralgia. 痛苦与狂喜:改进三叉神经痛的手术决策。
IF 0.8 3区 医学
Neurology India Pub Date : 2026-09-01 Epub Date: 2026-09-11 DOI: 10.4103/neurol-india.Neurol-India-D-26-00682
Dwarakanath Srinivas
{"title":"The Agony and the Ecstasy: Refining Surgical Decision-Making in Trigeminal Neuralgia.","authors":"Dwarakanath Srinivas","doi":"10.4103/neurol-india.Neurol-India-D-26-00682","DOIUrl":"10.4103/neurol-india.Neurol-India-D-26-00682","url":null,"abstract":"","PeriodicalId":19429,"journal":{"name":"Neurology India","volume":"74 5","pages":"837-839"},"PeriodicalIF":0.8,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148956348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Look at the History of the Brain Ventricles from the Perspective of Eponyms and Medical Education: Scoping Review. 从人名和医学教育的角度看脑室的历史:范围综述。
IF 0.8 3区 医学
Neurology India Pub Date : 2026-09-01 Epub Date: 2026-09-04 DOI: 10.4103/neurol-india.Neurol-India-D-25-00978
Hayriye Dilek Akdoğan, Ali Çağlar Turgut, Ilgaz Akdoğan, R Shane Tubbs
{"title":"A Look at the History of the Brain Ventricles from the Perspective of Eponyms and Medical Education: Scoping Review.","authors":"Hayriye Dilek Akdoğan, Ali Çağlar Turgut, Ilgaz Akdoğan, R Shane Tubbs","doi":"10.4103/neurol-india.Neurol-India-D-25-00978","DOIUrl":"10.4103/neurol-india.Neurol-India-D-25-00978","url":null,"abstract":"<p><strong>Abstract: </strong>The cerebral ventricles are fluid-filled cavities within the cerebral hemispheres and contain cerebrospinal fluid. Historically, the structure and presumed functions of the cerebral ventricles were often associated with the soul, intellect, memory, or mind. A comprehensive understanding of their true anatomy and functions emerged only through the application of scientific methods, including dissection, experimental research, and the correlation of structure with function. Many eponyms are reused to describe the anatomy of the cerebral ventricles. The aim of this study is to examine the historical development of the conceptualization of the ventricles and their interconnections, to elucidate their functions, and to investigate the origins of the eponyms commonly used in their anatomical description. The study was conducted as a scoping review in accordance with the PRISMA-ScR guidelines. PubMed, Web of Science, Scopus, and Google Scholar were searched. Data extraction and quality assessment were performed according to pre-established guidelines. The anatomical description of the cerebral ventricles can be traced back to Herophilus, Erasistratus, and Hippocrates and was further advanced by Galen (129-200). In the modern era, anatomical insight into the ventricles was refined through experimental research. Pioneering scholars such as Leonardo da Vinci (1452-1519), Andreas Vesalius (1514-1564), Franciscus de la Boe Sylvius (1614-1672), Alexander Monro (1733-1817), Domenico Cotugno (1736-1822), François Magendie (1783-1855), and Hubert von Luschka (1820-1875) made significant contributions to the field. An understanding of the historical emergence of eponymous terms and the processes by which anatomical structures were discovered is of considerable value in medical education.</p>","PeriodicalId":19429,"journal":{"name":"Neurology India","volume":" ","pages":"785-796"},"PeriodicalIF":0.8,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148897741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Gamma Knife Radiosurgery for Endolymphatic Sac Tumors: A Single-Institution Experience. 伽玛刀放射治疗内淋巴囊肿瘤:单一机构的经验。
IF 0.8 3区 医学
Neurology India Pub Date : 2026-09-01 Epub Date: 2026-09-04 DOI: 10.4103/neurol-india.Neurol-India-D-25-00986
Vedang Bhushan Mahajan, Sandeep Mishra, Kanwaljeet Garg, Ajay Garg, Manmohan Singh, P S Chandra
{"title":"Gamma Knife Radiosurgery for Endolymphatic Sac Tumors: A Single-Institution Experience.","authors":"Vedang Bhushan Mahajan, Sandeep Mishra, Kanwaljeet Garg, Ajay Garg, Manmohan Singh, P S Chandra","doi":"10.4103/neurol-india.Neurol-India-D-25-00986","DOIUrl":"10.4103/neurol-india.Neurol-India-D-25-00986","url":null,"abstract":"<p><strong>Background: </strong>Endolymphatic sac tumors (ELSTs) are rare, locally aggressive tumors often associated with von Hippel-Lindau disease. Due to their location and hypervascularity, complete surgical excision is challenging, and recurrence is common. Gamma knife radiosurgery (GKRS) has emerged as a potential noninvasive treatment modality, particularly in recurrent or inoperable cases.</p><p><strong>Methods: </strong>A retrospective analysis of five patients with radiologically diagnosed ELSTs treated with GKRS at our institution between 2012 and 2023 was performed. Patients who had received either upfront or adjuvant GKRS with a minimum of 1 year follow-up were included. Treatment planning involved frame-based MRI and GKRS delivery using the Leksell GammaPlan system. Clinical and radiological outcomes were assessed through clinical review and follow-up imaging.</p><p><strong>Results: </strong>Of the five patients, two received primary GKRS, and three received secondary GKRS following surgical resection. Marginal doses ranged from 20 to 25 Gy. At follow-up, MRIs showed stable disease with no increase in tumor size. Clinically, patients remained stable, with no worsening or emergence of new neurological symptoms. No procedure-related or radiation-induced complications, including radiation necrosis, were observed, and none required corticosteroid therapy.</p><p><strong>Conclusions: </strong>GKRS is a safe and effective treatment modality for the management of ELSTs, particularly in residual or recurrent disease. Our experience suggests that GKRS offers excellent radiological control and symptom stabilization, supporting its role as both a primary and adjunctive treatment option.</p>","PeriodicalId":19429,"journal":{"name":"Neurology India","volume":" ","pages":"864-869"},"PeriodicalIF":0.8,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148897653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Neural Circuit Dysfunctions in Migraine: A Stage-Specific Dynamic Perspective. 偏头痛的神经回路功能障碍:一个特定阶段的动态视角。
IF 0.8 3区 医学
Neurology India Pub Date : 2026-09-01 Epub Date: 2026-09-04 DOI: 10.4103/neurol-india.Neurol-India-D-26-00542
Dashan Lu, Ming Yao, Fan Bu, Ping He, Shizhen Wang, Longsheng Xu, Wenyu Chen, Qinli Feng
{"title":"Neural Circuit Dysfunctions in Migraine: A Stage-Specific Dynamic Perspective.","authors":"Dashan Lu, Ming Yao, Fan Bu, Ping He, Shizhen Wang, Longsheng Xu, Wenyu Chen, Qinli Feng","doi":"10.4103/neurol-india.Neurol-India-D-26-00542","DOIUrl":"10.4103/neurol-india.Neurol-India-D-26-00542","url":null,"abstract":"<p><strong>Abstract: </strong>Migraine is increasingly recognized as a cyclical brain state disorder rather than an isolated vascular or nociceptive condition. Its clinical phases may reflect dynamic reorganization of interacting neural circuits involved in sensory processing, homeostasis, pain modulation, and cognition. This review aims to synthesize current evidence and propose a stage-specific neural circuit dynamic model of migraine, linking each clinical phase to distinct patterns of circuit dysfunction and recovery. A narrative review of studies published between January 2010 and December 2024 was conducted using PubMed, Web of Science, and Embase. Controlled vocabulary and free-text terms were combined, and the article selection process was documented numerically to improve transparency. Evidence from human neuroimaging, electrophysiology, preclinical circuit manipulation, and neuromodulation studies was qualitatively integrated according to migraine phase and circuit domain. The interictal phase is characterized by vulnerable homeostasis, with heightened cortical excitability, impaired sensory gating, and weakened descending inhibition. During the prodromal phase, hypothalamic involvement and altered limbic-reward signaling may contribute to attack-related network priming. The ictal phase involves trigeminovascular activation, thalamocortical amplification, and engagement of pain and sensory networks; in migraine with aura, cortical spreading depression may contribute to these processes. Attack resolution may involve endogenous reset mechanisms engaging brainstem and hypothalamic modulatory systems, whereas chronic migraine may reflect maladaptive circuit plasticity and more persistent network reconfiguration. A stage-specific circuit framework can integrate fragmented evidence on migraine pathophysiology and may support circuit-based biotyping, biomarker development, and targeted neuromodulatory or pharmacological interventions.</p>","PeriodicalId":19429,"journal":{"name":"Neurology India","volume":" ","pages":"775-784"},"PeriodicalIF":0.8,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148897662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
"Bihemispheric Jacksonian March" In Autoimmune Epilepsy. 自身免疫性癫痫的“双脑杰克逊三月”
IF 0.8 3区 医学
Neurology India Pub Date : 2026-09-01 Epub Date: 2026-08-19 DOI: 10.4103/neurol-india.Neurol-India-D-25-00789
Jomal Mathew
{"title":"\"Bihemispheric Jacksonian March\" In Autoimmune Epilepsy.","authors":"Jomal Mathew","doi":"10.4103/neurol-india.Neurol-India-D-25-00789","DOIUrl":"10.4103/neurol-india.Neurol-India-D-25-00789","url":null,"abstract":"","PeriodicalId":19429,"journal":{"name":"Neurology India","volume":" ","pages":"914-916"},"PeriodicalIF":0.8,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148796149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Claustrum Sign in Febrile Infection-Related Epilepsy Syndrome. 发热性感染相关性癫痫综合征的闭锁征。
IF 0.8 3区 医学
Neurology India Pub Date : 2026-09-01 Epub Date: 2026-08-19 DOI: 10.4103/neurol-india.Neurol-India-D-25-01018
Aarman Saanea Khan, Bheru Dan Charan, Akash Rauniyar, Michael Kumar Sah
{"title":"Claustrum Sign in Febrile Infection-Related Epilepsy Syndrome.","authors":"Aarman Saanea Khan, Bheru Dan Charan, Akash Rauniyar, Michael Kumar Sah","doi":"10.4103/neurol-india.Neurol-India-D-25-01018","DOIUrl":"10.4103/neurol-india.Neurol-India-D-25-01018","url":null,"abstract":"","PeriodicalId":19429,"journal":{"name":"Neurology India","volume":" ","pages":"947-948"},"PeriodicalIF":0.8,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148796230","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Chiari Malformation: From Posterior Fossa Decompression to Atlantoaxial Stabilization-Has the Instability Concept Redefined the Disease? Chiari畸形:从后窝减压到寰枢椎稳定-不稳定的概念是否重新定义了该疾病?
IF 0.8 3区 医学
Neurology India Pub Date : 2026-09-01 Epub Date: 2026-09-11 DOI: 10.4103/neurol-india.Neurol-India-D-26-00693
Atul Goel
{"title":"Chiari Malformation: From Posterior Fossa Decompression to Atlantoaxial Stabilization-Has the Instability Concept Redefined the Disease?","authors":"Atul Goel","doi":"10.4103/neurol-india.Neurol-India-D-26-00693","DOIUrl":"10.4103/neurol-india.Neurol-India-D-26-00693","url":null,"abstract":"","PeriodicalId":19429,"journal":{"name":"Neurology India","volume":"74 5","pages":"771-772"},"PeriodicalIF":0.8,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148956213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Autoimmune Encephalitis: A Case Series from a Tertiary Care Center in South India. 自身免疫性脑炎:来自印度南部三级保健中心的病例系列。
IF 0.8 3区 医学
Neurology India Pub Date : 2026-09-01 Epub Date: 2026-09-04 DOI: 10.4103/neurol-india.Neurol-India-D-26-00412
N S Manoj Kumar, A Santhosh Kumar, Vignesh Anbalagan, Marian Jude Vijay, N Shanmuga Sundaram, Mugundhan Krishnan
{"title":"Autoimmune Encephalitis: A Case Series from a Tertiary Care Center in South India.","authors":"N S Manoj Kumar, A Santhosh Kumar, Vignesh Anbalagan, Marian Jude Vijay, N Shanmuga Sundaram, Mugundhan Krishnan","doi":"10.4103/neurol-india.Neurol-India-D-26-00412","DOIUrl":"10.4103/neurol-india.Neurol-India-D-26-00412","url":null,"abstract":"<p><strong>Abstract: </strong>Autoimmune encephalitis (AE) is a heterogeneous group of immune-mediated disorders of the central nervous system characterized by neuropsychiatric symptoms, seizures, cognitive decline, and movement abnormalities. Timely recognition and initiation of immunotherapy are critical to improving outcomes. We report three cases of AE presenting with varied clinical phenotypes from the Neurology department of Madras Medical College. The first, a 44-year-old male, presented with altered sensorium, action tremor, and myokymia, and was diagnosed with LGI1 and CASPR2 antibody-positive AE. The second, a 16-year-old girl, presented with seizures, progressive cognitive decline, behavioral disturbance, and focal weakness, confirmed as anti-NMDAR encephalitis. The third, a 14-year-old boy, developed seizures and behavioral changes following herpes simplex encephalitis and was later confirmed to have anti-NMDAR antibody-positive AE with features of Kluver-Bucy syndrome. All patients received first-line immunotherapy (steroids, IVIg), with escalation to rituximab in resistant cases.</p>","PeriodicalId":19429,"journal":{"name":"Neurology India","volume":" ","pages":"908-911"},"PeriodicalIF":0.8,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148897727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Renal Artery Lesions in Moyamoya Disease. 烟雾病肾动脉病变。
IF 0.8 3区 医学
Neurology India Pub Date : 2026-09-01 Epub Date: 2026-08-19 DOI: 10.4103/neurol-india.Neurol-India-D-26-00068
Poornima Nair, Manuraj Natarajan, E R Jayadevan, Sapna E Sreedharan, P N Sylaja
{"title":"Renal Artery Lesions in Moyamoya Disease.","authors":"Poornima Nair, Manuraj Natarajan, E R Jayadevan, Sapna E Sreedharan, P N Sylaja","doi":"10.4103/neurol-india.Neurol-India-D-26-00068","DOIUrl":"10.4103/neurol-india.Neurol-India-D-26-00068","url":null,"abstract":"","PeriodicalId":19429,"journal":{"name":"Neurology India","volume":" ","pages":"917-918"},"PeriodicalIF":0.8,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148796162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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