{"title":"Traumatic Cervical Spondyloptosis: A Comprehensive Analysis of 16 Cases at a Level 1 Trauma Center in a Developing Nation.","authors":"Hitesh Inder Singh Rai, Sandeep Mishra, Tungish Bansal, Kanwaljeet Garg, Shashwat Mishra, Pankaj Kumar Singh, Santanu Kumar Bora, Sachin Borkar, Dattaraj Sawarkar, Ramesh Doddamani, Shweta Kedia, Satish Verma, Rajeev Sharma, Deepak Agrawal, Deepak Gupta, P S Chandra, Shashank Sharad Kale","doi":"10.4103/neurol-india.Neurol-India-D-24-00116","DOIUrl":"https://doi.org/10.4103/neurol-india.Neurol-India-D-24-00116","url":null,"abstract":"<p><strong>Background: </strong>Traumatic cervical spondyloptosis (TCS) is a rare and the most severe form of cervical spine injury.</p><p><strong>Aims/objective: </strong>The primary and secondary objectives were assessment of improvement in neurological status and rate of complications respectively.</p><p><strong>Methods: </strong>Sixteen patients of TCS operated between 2015 and 2019 were included. The pertinent details including demographics, neurological status, associated injuries, reduction method, surgical approach, complications, and outcomes at follow-up were recorded.</p><p><strong>Results: </strong>The mean age was 35.0 ± 12.1 (range 16-65). Fall from height (56%) and road traffic accidents (37.5%) were the common modes of injury. The most common level of injury was C6-C7 in eight patients, C5-C6 in five patients, and C7-T1 in two patients. The neurological status was ASIA A, D, and B in 12, 3, and 1 patients, respectively. Seven patients had one or more associated injuries. Surgical approaches included anterior (A), anterior and posterior (AP), and APA approach in 8, 6, and 2 patients, respectively. Cerebrospinal fluid leak was noticed in six cases. The median postoperative ICU stay was 17.5 days (2-80 days). Ten (62.5%) patients had one or more major postoperative complications. Four patients died during the hospital course. Of the 10/12 discharged patients who followed up, 6 patients (ASIA A) expired within 12 months from complications of recumbency. Three out of the remaining four patients, who survived, showed improvement.</p><p><strong>Conclusion: </strong>We report the largest case series of TCS to the best of our knowledge. These cases can be a surgical challenge, and complications and outcomes depend on the function of preoperative neurological status of the patient.</p>","PeriodicalId":19429,"journal":{"name":"Neurology India","volume":"73 3","pages":"454-462"},"PeriodicalIF":0.9,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144131895","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Neurology IndiaPub Date : 2025-05-01Epub Date: 2025-05-23DOI: 10.4103/neurol-india.Neurol-India-D-24-00457
Andrei Fernandes Joaquim, Eloy Rusafa Neto, Leon Cleres Penido Pinheiro, Osmar Jose Santos de sMoraes, Eberval Gadelha Figueiredo, Carlos Gilberto Carloti, Roger Schimdt Brock
{"title":"Surgical Treatment of Basilar Invagination without Evident Atlantoaxial Instability (Type B) - A Systematic Review.","authors":"Andrei Fernandes Joaquim, Eloy Rusafa Neto, Leon Cleres Penido Pinheiro, Osmar Jose Santos de sMoraes, Eberval Gadelha Figueiredo, Carlos Gilberto Carloti, Roger Schimdt Brock","doi":"10.4103/neurol-india.Neurol-India-D-24-00457","DOIUrl":"https://doi.org/10.4103/neurol-india.Neurol-India-D-24-00457","url":null,"abstract":"<p><p>Chiari 1 malformation (CM1) and Basilar Invagination (BI) are the most common congenital bone and neural disorders of the craniovertebral junction. There is still discussion in the literature regarding best treatment practices for Type B BI. This systematic review aims to evaluate the treatment options for symptomatic type B BI especially concerning the need for craniocervical fusion. We performed a systematic literature review, focusing on surgical studies of patients with type B BI that reported the surgical technique used and the clinical outcomes. The MINORS instrument was utilized for methodological quality assessment as well as the level of evidence (LOL) of the included studies. Six studies were included, two of which used similar patients' samples. Posterior fossa decompression (PFD) with or without duroplasty was employed in three studies, C1-2 fusion in one, and C1-2 distraction and fusion in two studies. All reported patients' improvement post-surgery regardless of the technique used. Failure of PFD was associated with bone segmental anomalies in one study, and early deaths were associated with C1-2 fusion. The quality of the included studies was acceptable, with four studies at LOL 4 and two studies at LOL 3. There are varying surgical treatments for type B BI. PFD (most often with duroplasty) is safe and effective for patients without ventral compression. Some authors recommended C1-2 stabilization in all cases, and reported clinical improvement. Until prospective comparative studies, the ideal treatment option for type B BI remains unclear.</p>","PeriodicalId":19429,"journal":{"name":"Neurology India","volume":"73 3","pages":"423-428"},"PeriodicalIF":0.9,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144132694","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"An Unusual Case of Two Large Aneurysms Arising from Opposite Walls of Right Internal Carotid Artery Cavernous Segment and its Management.","authors":"Batuk Diyora, Anup Purandare, Kavin Devani, Ravi Wankhade, Sagar Gawali, Prakash Palave, Rushabh Chheda","doi":"10.4103/ni.ni_479_22","DOIUrl":"10.4103/ni.ni_479_22","url":null,"abstract":"","PeriodicalId":19429,"journal":{"name":"Neurology India","volume":" ","pages":"580-583"},"PeriodicalIF":0.9,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142771017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Neurology IndiaPub Date : 2025-05-01Epub Date: 2024-11-29DOI: 10.4103/ni.ni_302_20
Tom Kakkanattu, Jasmine Sethi, Smita Divyaveer, K V Mahesh, Raja Ramachandran, Harbir S Kohli
{"title":"Sensorimotor Neuropathy with Chronic Kidney Disease: A Rare Etiology.","authors":"Tom Kakkanattu, Jasmine Sethi, Smita Divyaveer, K V Mahesh, Raja Ramachandran, Harbir S Kohli","doi":"10.4103/ni.ni_302_20","DOIUrl":"10.4103/ni.ni_302_20","url":null,"abstract":"","PeriodicalId":19429,"journal":{"name":"Neurology India","volume":" ","pages":"594-595"},"PeriodicalIF":0.9,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142771063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pseudotumor Cerebri Syndrome Precipitated by Ketoconazole Therapy in a Patient with Persistent Cushing's Disease Following Trans-Sphenoidal Surgery and Radiotherapy.","authors":"Niya Narayanan, Ayan Roy, Chandhana Merugu, Sadishkumar Kamalanathan, Jayaprakash Sahoo, Dukhabandhu Naik, Pradeep Nair","doi":"10.4103/ni.ni_478_21","DOIUrl":"10.4103/ni.ni_478_21","url":null,"abstract":"","PeriodicalId":19429,"journal":{"name":"Neurology India","volume":" ","pages":"604-606"},"PeriodicalIF":0.9,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143458885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Neurology IndiaPub Date : 2025-05-01Epub Date: 2025-05-23DOI: 10.4103/neurol-india.Neurol-India-D-23-00265
Guru C Desari, Kiran Jangra, Virendra K Arya, Sabina Regmi, Ashish Aggarwal, Hemant Bhagat, Nidhi B Panda, Shiv L Soni, Summit D Bloria
{"title":"Transthoracic Echocardiography for Assessing the Preoperative Hypovolemia in Patients with Aneurysmal Subarachnoid Hemorrhage: A Prospective Observational Study.","authors":"Guru C Desari, Kiran Jangra, Virendra K Arya, Sabina Regmi, Ashish Aggarwal, Hemant Bhagat, Nidhi B Panda, Shiv L Soni, Summit D Bloria","doi":"10.4103/neurol-india.Neurol-India-D-23-00265","DOIUrl":"https://doi.org/10.4103/neurol-india.Neurol-India-D-23-00265","url":null,"abstract":"<p><strong>Background: </strong>Volume disturbances frequently occur after aneurysmal subarachnoid hemorrhage (a-SAH). Both hypovolemia and hypervolemia are associated with poor outcomes. Hence, we planned this study to determine preoperative volume status using echocardiography.</p><p><strong>Objectives: </strong>The primary objective was to determine the incidence of preoperative hypovolemia in a-SAH patients with echocardiography. The secondary objectives include association between hypovolemia and induction hypotension and relative risk, and relative sensitivity and specificity of echocardiographic indices in predicting induction hypotension.</p><p><strong>Methods and material: </strong>Ninety-eight ASA-I or -II patients, aged 18-65 years, undergoing aneurysmal clipping surgery were included. Hypovolemia was assessed by inferior vena cava (IVC) diameter, IVC collapsibility index in subcostal view, left ventricular end-diastolic area and kissing-papillary sign in parasternal short axis view, and variations in left-ventricular outflow tract velocity-time integral (LVOT-VTI) in apical view. Induction-hypotension was defined as mean arterial pressure <70 mm of Hg until 10 min after induction.</p><p><strong>Results: </strong>Out of 98 patients, 69 (70%) were hypovolemic and 59 (60%) developed induction hypotension with a relative risk of 2.26. The IVC-Cx and LVOT-VTI were the most sensitive parameters for determining induction hypotension (76% and 91%, respectively). A combination of IVC-Cx and kissing-papillary signs were most reliable for determining induction hypotension (P = 0.010).</p><p><strong>Conclusions: </strong>We conclude that the incidence of preoperative hypovolemia was 70%, and 60% of patients had induction hypotension. Dynamic parameters including IVC-Cx and VTI-variations are more reliable in predicting induction hypotension. We emphasize that preoperative screening of patients using ultrasound helps identify the hypovolemic patients in the preoperative area.</p>","PeriodicalId":19429,"journal":{"name":"Neurology India","volume":"73 3","pages":"474-479"},"PeriodicalIF":0.9,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144131931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Neurology IndiaPub Date : 2025-05-01Epub Date: 2025-05-23DOI: 10.4103/neurol-india.Neurol-India-D-24-00656
Josef Finsterer
{"title":"Hyperintensity in Diffusion-Weighted Imaging is not Necessarily a Sign of Ischemic Stroke.","authors":"Josef Finsterer","doi":"10.4103/neurol-india.Neurol-India-D-24-00656","DOIUrl":"https://doi.org/10.4103/neurol-india.Neurol-India-D-24-00656","url":null,"abstract":"","PeriodicalId":19429,"journal":{"name":"Neurology India","volume":"73 3","pages":"567"},"PeriodicalIF":0.9,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144132681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}