Neurology India最新文献

{"title":"Childhood Chronic Progressive Ataxia with Normal Neuroimaging: Think of CONDSIAS.","authors":"Singanamalla Bhanudeep, Bramhini Bhargavi Koneti","doi":"10.4103/neurol-india.Neurol-India-D-24-00642","DOIUrl":"10.4103/neurol-india.Neurol-India-D-24-00642","url":null,"abstract":"","PeriodicalId":19429,"journal":{"name":"Neurology India","volume":" ","pages":"568-569"},"PeriodicalIF":0.9,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142771027","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rheumatoid Pachymeningitis as the Sole Manifestation of Rheumatoid Arthritis.","authors":"Akanksha Choudhary, Shubhakaran Khichar, Amita Bhargava, Arvind Lakesar","doi":"10.4103/ni.ni_113_20","DOIUrl":"10.4103/ni.ni_113_20","url":null,"abstract":"","PeriodicalId":19429,"journal":{"name":"Neurology India","volume":" ","pages":"592-593"},"PeriodicalIF":0.9,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142771040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hangman's Fracture (Atypical Type) with Vertebral-Venous Fistula Following Blunt Trauma to the Cervical Spine.","authors":"Rajesh Meena, Pankaj K Singh, Kalyan Sarma, Leve Joseph Devarajan Sebastian, Ramesh S Doddamani, Sarat P Chandra","doi":"10.4103/ni.ni_524_21","DOIUrl":"10.4103/ni.ni_524_21","url":null,"abstract":"","PeriodicalId":19429,"journal":{"name":"Neurology India","volume":" ","pages":"596-599"},"PeriodicalIF":0.9,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143458833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Neuroimaging in Listeria Rhombencephalitis: Hydrocephalus and Parenchymal Hemorrhages as Key Findings.","authors":"Sayooja Sachithanandan, Adarsh Anil, Asish Vijayaraghavan, Soumya Sundaram, Sajith Sukumaran","doi":"10.4103/neurol-india.Neurol-India-D-24-00662","DOIUrl":"10.4103/neurol-india.Neurol-India-D-24-00662","url":null,"abstract":"","PeriodicalId":19429,"journal":{"name":"Neurology India","volume":" ","pages":"636-637"},"PeriodicalIF":0.9,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143996315","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Formation of the NSI-Young Neurosurgeons Forum and the Fellowship Landscape in India: Wants vs Needs.","authors":"Harsh Deora, Md Krishna Narayanan, Manjul Tripathi, Prashant Punia, Sachin Chemate, P Anabhazaghan, Prakash Nair, Venkatesh Madugiri, Binoy Kumar, Sukirti Chauhan, Vamsi Krishna, Sachin Borkar, V R Roopesh Kumar, K Sridhar, Manas Panigrahi, V P Singh","doi":"10.4103/neurol-india.Neurol-India-D-25-00228","DOIUrl":"10.4103/neurol-india.Neurol-India-D-25-00228","url":null,"abstract":"<p><strong>Background: </strong>Post-residency fellowship training is essential for neurosurgeons to gain expertise in specialized subspecialties. In India, where residency programs are not standardized, inadequate exposure to subspecialties, in many institutes, drives young neurosurgeons to seek fellowship training. The fellowship landscape remains fragmented, with formal programs accredited by bodies like CAST (USA) and RCS (UK), alongside informal observer ship. Understanding the expectations and barriers faced by fellowship aspirants can help tailor Indian fellowship programs to meet these needs effectively.</p><p><strong>Objective: </strong>This study aims to evaluate the needs and preferences of young neurosurgeons in India regarding fellowship training. It also seeks to understand the perspectives of fellowship directors to align aspirants' expectations with available training opportunities.</p><p><strong>Methods and materials: </strong>A cross-sectional survey was conducted among members of the Neurological Society of India (NSI) under 40 years of age. Eligible participants included neurosurgeons in residency or within 4 years of completion. The survey assessed demographic details, residency exposure, preferred fellowship duration, location, subspecialty interests, barriers to training, and directors' perspectives. Responses were collected electronically over 3 months.</p><p><strong>Results: </strong>A total of 177 respondents participated, with 81.9% currently in or recently out of residency. Exposure to subspecialties varied significantly, with high exposure in trauma (61.5%) but low exposure in functional, epilepsy, and endovascular neurosurgery (46.3% and 43.5% reporting \"less than adequate\"). A majority (52%) pursued fellowships for skill enhancement, preferring domestic programs (65.5%) over international ones. The most cited barriers included financial constraints (37.9%) and relocation concerns (12.4%). Fellowship directors emphasized the need for structured training, technical proficiency, and accreditation to enhance career prospects.</p><p><strong>Conclusion: </strong>This study highlights systemic gaps in Indian neurosurgical fellowship training, emphasizing the need for modular programs, improved financial aid, and standardized curricula. Strengthening domestic training infrastructure and fostering global collaborations can bridge these gaps, ensuring young neurosurgeons receive adequate subspecialty training.</p>","PeriodicalId":19429,"journal":{"name":"Neurology India","volume":"73 3","pages":"557-564"},"PeriodicalIF":0.9,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144476166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Awake Sciatic Nerve Neurolysis after Injection Injury - An Innovative Technique and Our Experience.","authors":"Ishu Bishnoi, Alberto Feletti, Amanpreet Singh, Bansi Lal, Devendra Kumar","doi":"10.4103/neurol-india.Neurol-India-D-24-00763","DOIUrl":"10.4103/neurol-india.Neurol-India-D-24-00763","url":null,"abstract":"<p><strong>Background and introduction: </strong>Sciatic nerve injection injury is the most common type of injection nerve injury. Injection injury to nerve causes severe, intractable radicular pain in affected limb. Owing to chemical damage, nerve is damaged both mechanically and chemically. As a result, adhesions and nerve fibers damage is more than expected. Surgical neurolysis is recommended for pain relief. However it is done in general anesthesia and effect of neurolysis is checked only after reversal.</p><p><strong>Objective: </strong>There are chances that incomplete neurolysis can cause persistence of pain. To overcome this limitation, we evaluated \"awake sciatic neurolysis technique.\"</p><p><strong>Methods: </strong>This was a prospective, nonrandomized study which evaluated awake sciatic neurolysis in sciatic nerve injection injury patients. A total of 11 patients underwent this procedure after evaluating clinical profile. During this procedure, patients were asked about pain relief on rest and leg movement. When VAS score decreased to 3 or less, procedure was stopped.</p><p><strong>Results: </strong>The average VAS score was 9.5 (10 in 7 cases). During surgery, VAS score decreased to 3 and below in all except in 2 cases. In long-term follow-up, one patient had VAS more than 3.</p><p><strong>Conclusion: </strong>Our study is about a novel technique \"awake sciatic neurolysis.\" The results were satisfactory, but it has some technical difficulties. It has advantage of checking impact of neurolysis during surgery and modify technique according to relief.</p>","PeriodicalId":19429,"journal":{"name":"Neurology India","volume":"73 3","pages":"546-550"},"PeriodicalIF":0.9,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144476081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cerebellum-Predominant Progressive Multifocal Leukoencephalopathy: An Under-recognized Cause of Cerebellar Syndrome among People with Human Immunodeficiency Virus Infection.","authors":"Selwyn Selva Kumar, Priyanka Gautam, Harshad Arvind Vanjare, P Prasanna Kumar, Asha Mary Abraham, Rajiv Karthik, Abi Manesh","doi":"10.4103/neurol-india.Neurol-India-D-23-00603","DOIUrl":"10.4103/neurol-india.Neurol-India-D-23-00603","url":null,"abstract":"<p><p>Progressive multifocal leukoencephalopathy (PMLE) is caused by severe cortical demyelination due to reactivation of the polyomavirus, JC virus in profound immunosuppression, like advanced HIV infection. Cerebellum-predominant PMLE is rare and underreported. We report seven patients with confirmed cerebellum-predominant PMLE from a quaternary care center in South India over a five-year period. We report their outcomes and disability using modified Rankin scores (mRS). All seven patients had advanced HIV infection with low CD4 counts [median (IQR) 79 (51-155) cells/μL]. Ataxia (5/7; 71.4%), dysarthria (4/7; 57.1%), and vertigo (2/7; 28.5%) were the common symptoms at presentation. Cerebellar hemisphere or cerebellar peduncles with or without brainstem involvement were noted in all patients. Concomitant supratentorial involvement was also present in six patients. 'Shrimp sign' was seen in five of the seven patients. Only one patient had significant neurological recovery on follow-up. Cerebellum predominant PMLE is a severe, disabling opportunistic infection among patients with advanced HIV infection.</p>","PeriodicalId":19429,"journal":{"name":"Neurology India","volume":"73 3","pages":"519-523"},"PeriodicalIF":0.9,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144476082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Encephalocraniocutaneous Lipomatosis - A Rare Neurophakomatoses.","authors":"Jaya Pamnani, Sarbesh Tiwari, Taruna Yadav, Kavita R Bhatnagar","doi":"10.4103/ni.ni_799_21","DOIUrl":"10.4103/ni.ni_799_21","url":null,"abstract":"","PeriodicalId":19429,"journal":{"name":"Neurology India","volume":" ","pages":"620-622"},"PeriodicalIF":0.9,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143458821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Serum Cytokine 6, 10 and α-Tumour Necrosis Factor Levels in Alzheimer's Disease Subjects Treated with Donepezil Plus Vitamin B12.","authors":"Neelam Yeram, Shubhangi M Dalvi, Vinayak P Kale, Vinayak W Patil, Ranjit Mankeshwar, Kamlesh Jagiasi, Leela G Abichandani","doi":"10.4103/neuroindia.NI_1615_20","DOIUrl":"10.4103/neuroindia.NI_1615_20","url":null,"abstract":"<p><strong>Background: </strong>Neuroinflammation is a key feature of Alzheimer's disease (AD) pathology.</p><p><strong>Objectives: </strong>The aim of this study was to investigate the serum levels of Cytokine 6 (Cyto-6), Cytokine 10 (Cyto-10), and alpha-tumor necrosis factor (α-TNF) in Alzheimer's disease patients and observe the effects of donepezil plus vitamin B12 (VB12) treatment on these cytokines.</p><p><strong>Methods and materials: </strong>Seventy-one AD cases and 70 controls with age more than 60 years. Cyto-6, Cyto-10, and α-TNF were measured using the Chemiluminescence Immulite 1000 system, Siemens. Alzheimer's disease subjects were treated with donepezil (5 mg/day) plus VB12 (1.5 mg/day) supplement for 6 months, and serum cytokine levels were reinvestigated. Statistical analysis was done using SPSS software.</p><p><strong>Result: </strong>Cyto-6, Cyto-10, and α-TNF values were raised in Alzheimer's disease as compared to controls (P < 0.001) [AD (Cyto-6: 10.27 ± 2.76 pg/ml; Cyto-10: 6.2 ± 1.48 pg/ml; α-TNF: 26.49 ± 6.85 pg/ml) and Control (Cyto-6: 3.29 ± 0.77 pg/ml; Cyto-10: 8.213 ± 0.787 pg/ml; α-TNF: 5.18 ± 1.65 pg/ml)]. After 6 months, a significant decrease (P < 0.01) was observed in Cyto-6 (7.95 ± 2.21 pg/ml), Cyto-10 (4.77 ± 1.12 pg/ml), and α-TNF (22.67 ± 7.00 pg/ml) levels in AD.</p><p><strong>Conclusion: </strong>We conclude that serum Cyto-6, Cyto-10, and α-TNF play an inflammatory role in Alzheimer's disease progression. Combined therapy of donepezil and VB12 supplement showed a beneficial effect in reducing inflammation. This study might benefit further research along with molecular follow-up studies for development of novel therapeutic strategies in Alzheimer's disease.</p>","PeriodicalId":19429,"journal":{"name":"Neurology India","volume":"73 3","pages":"488-494"},"PeriodicalIF":0.9,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144132693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lessons Learnt From Glioblastoma Surviving 20 Years Progression Free: A Case Report.","authors":"Vyom Bhargava","doi":"10.4103/neurol-india.Neurol-India-D-24-00487","DOIUrl":"10.4103/neurol-india.Neurol-India-D-24-00487","url":null,"abstract":"<p><p>Glioblastoma (GBM), the commonest primary brain tumor, mostly dies in 2-3 years, despite all the latest advances. Shorter lifespan justifying subtotal resection for functional preservation, a common, but not optimum scenario for patients. A 22-year-old man with raised intracranial pressure and focal deficits underwent Gross total removal (GTR). Following irradiation, he has survived for over 20 years since his first brain CT, and the latest MRI has no recurrence. This case provides the possibility of giving HOPE of living long to the next suspected glioblastoma during consent or counseling and a reason to achieve GTR in most cases to find some of such lucky cases. The specimen should be preserved for newer tests in the future. Building meaningful relationships with patients is needed for long follow-ups.</p>","PeriodicalId":19429,"journal":{"name":"Neurology India","volume":"73 3","pages":"541-543"},"PeriodicalIF":0.9,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144132687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}