Neuroradiology最新文献

{"title":"Understanding complication rates in elective endovascular aneurysm repair for consideration of same-day discharge.","authors":"Aliana N Rao, Theodore C Hannah, Emily B Harvey, Erin K M Graves, Eric T Quach, Kadir Erkmen, Rami O Almefty","doi":"10.1007/s00234-026-04185-4","DOIUrl":"https://doi.org/10.1007/s00234-026-04185-4","url":null,"abstract":"<p><strong>Objective: </strong>Elective repair of unruptured intracranial aneurysms (UIA) is performed to prevent potentially catastrophic rupture. There exists potential for outpatient elective endovascular aneurysm repair given low risk for complications. However, concern remains for development of delayed post-operative complications, which has led to overnight observation being common practice. We aim to determine this practice's necessity by identifying rate and timing of delayed complications and associated factors.</p><p><strong>Methods: </strong>All patients undergoing elective endovascular UIA treatment between 2014 and 2024 were included. Demographic and clinical data, including primary aneurysm location and size, complications, anticoagulant/antiplatelet (AC/AP) use, and discharge destination was collected.</p><p><strong>Results: </strong>Of 151 patients, 4 experienced intra-operative complications and 9 (5.9%) experienced post-operative complications. The average time to post-operative complication was 4.67 hours. MCA aneurysms were found to be an independent risk factor for peri-procedural complication (OR = 9.65, 95% CI: 1.15-80.7, p = 0.03). Conversely, no peri-procedural complications were seen when treating posterior circulation aneurysms. Although a significant proportion of peri-procedural complications were associated with bleeding, the rate of peri-procedural complications was not significantly higher in those on AC/AP. All but two peri-procedural complications resolved by discharge, with one resolving upon follow-up. The rate of permanent deficit from peri-procedural complications was 0.66%.</p><p><strong>Conclusion: </strong>Elective repair of UIA carries a low post-operative complication rate (5.9%) and a very low permanent complication rate (0.66%) in this study. The incidence of delayed complication is low, however, it does occur at a mean time of nearly 5 hours and up to 24 hours requiring additional hospital-based services for diagnosis and management. Based on these findings, we advocate for continued practice of overnight observation.</p>","PeriodicalId":19422,"journal":{"name":"Neuroradiology","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2026-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148990643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Minocycline for neuroprotection in stroke and cerebral ischemia: a systematic review and meta-analysis.","authors":"Omar Fayez Abbas, Aya Magdy Siam, Abdullah Almarfadi, Nour Aldin T Ahmed, Roaa Haddad, Ahmed Harb, Hannah Hurtig, Hasan Banihani, Mohamed Hamouda, Abdelrahman M Hamouda, Sherief Ghozy, Ram Kadrivel, Kogulavadanan Arumathurai, David F Kallmes","doi":"10.1007/s00234-026-04173-8","DOIUrl":"https://doi.org/10.1007/s00234-026-04173-8","url":null,"abstract":"<p><strong>Background: </strong>Stroke remains a leading cause of mortality and long-term disability worldwide, with substantial socioeconomic and healthcare burdens. Minocycline, a tetracycline antibiotic with anti-inflammatory and antioxidant properties and the ability to cross the blood-brain barrier, has emerged as a potential neuroprotective agent in acute ischemic stroke (AIS). However, clinical evidence remains inconsistent. This systematic review and meta-analysis aimed to evaluate the efficacy and safety of minocycline in patients with AIS.</p><p><strong>Methods: </strong>We systematically searched PubMed, Scopus, Web of Science, and the Cochrane Library from inception to February 2026 for randomized controlled trials (RCTs) evaluating minocycline in adults with AIS. The primary outcomes were functional outcomes assessed using the modified Rankin Scale (mRS) and neurological outcomes assessed using the National Institutes of Health Stroke Scale. Dichotomous outcomes were pooled as risk ratios (RRs), while continuous outcomes were synthesized as mean differences (MDs), each with 95% confidence intervals (CIs), using random-effects meta-analysis with restricted maximum likelihood estimation. The Hartung-Knapp-Sidik-Jonkman adjustment was applied.</p><p><strong>Results: </strong>Seven RCTs comprising 2,242 patients (1,113 receiving minocycline and 1,129 receiving placebo) were included. Minocycline was not associated with a statistically significant difference in continuous mRS scores at 90 days (MD = - 0.88; 95% CI: -4.03 to 2.28; p = 0.18; I² = 53.2%). Similarly, minocycline did not significantly improve excellent functional outcome (mRS 0-1) (RR = 1.09; 95% CI: 0.95-1.26; p = 0.14; I² = 0%) or functional independence (mRS 0-2) (RR = 1.05; 95% CI: 0.69-1.59; p = 0.76; I² = 65.2%). Similarly, minocycline was not associated with a statistically significant reduction in NIHSS scores at 90 days (MD = - 2.52; 95% CI: -5.37 to 0.33; p = 0.06) or improvement in BI scores (MD = 8.13; 95% CI: -29.32 to 45.58; p = 0.22). No significant differences were found in stroke recurrence (RR = 1.07; 95% CI: 0.70-1.61; p = 0.58) or mortality (RR = 0.69; 95% CI: 0.40-1.20; p = 0.12).</p><p><strong>Conclusions: </strong>Minocycline did not demonstrate a statistically significant improvement in functional or neurological outcomes at 90 days compared with the control group. The available evidence suggests no significant increase in stroke recurrence or mortality. Further large-scale, high-quality RCTs are warranted to clarify the potential neuroprotective effects of minocycline and determine its role in the routine management of AIS.</p>","PeriodicalId":19422,"journal":{"name":"Neuroradiology","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2026-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148983337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Angioplasty and stenting of symptomatic intracranial atherosclerotic stenosis: a dual-center experience using NeuroSpeed balloon-catheter and CREDO heal stent.","authors":"Tawfik Moher Alsady, Abdallah Aburub, Oussama Dob, André Kemmling, Mohammad Almohammad","doi":"10.1007/s00234-026-04181-8","DOIUrl":"https://doi.org/10.1007/s00234-026-04181-8","url":null,"abstract":"<p><strong>Background: </strong>Intracranial atherosclerotic stenosis (ICAS) remains a significant cause of recurrent ischemic strokes. While aggressive medical management is the mainstay of treatment, percutaneous transluminal angioplasty (PTA) and intracranial stenting (ICS) are increasingly used, especially in cases refractory to medical therapy or as a bailout during frustrating thrombectomy.</p><p><strong>Objective: </strong>To evaluate the safety, technical feasibility, and short-term outcomes of NeuroSpeed balloon-catheter angioplasty and CREDO heal stent implantation in patients with symptomatic ICAS with and without large or medium vessel occlusion (LVO/MeVO).</p><p><strong>Methods: </strong>This retrospective, dual-center study included 42 patients who underwent ICS using the NeuroSpeed balloon-catheter and fibrin-heparin coated CREDO heal stent. Patients were divided into two subgroups: ICAS (n = 23) and Bailout stenting (n = 19). Procedural success with a stenosis grade reduction to ≤ 50%, complication rates, and clinical outcomes were analyzed.</p><p><strong>Results: </strong>Technical success was achieved in 83% of cases. Clinical improvement was significant between baseline and follow-up, with a reduction in the median modified Rankin Scale score from 2 to 0 (p = 0.005). Acute stent occlusion occurred in 2 of 19 patients (10.5%) in the bailout group. Late vascular follow-up imaging was available in 30 patients; two asymptomatic delayed stent occlusions occurred in the ICAS group (2/23, 8.7%) and two cases of in-stent restenosis in the bailout group (2/19, 10.5%). Procedure-related intracranial hemorrhage occurred in one patient in the ICAS group (1/23, 4.3%) and one patient in the bailout group (1/19, 5.3%). One access-site pseudoaneurysm (1/42, 2.4%) was observed.</p><p><strong>Conclusion: </strong>NeuroSpeed/CREDO-based intracranial stenting appears to be a technically feasible treatment for high-grade ICAS and as a bailout during thrombectomy, with favorable short-term clinical outcomes and acceptable complication rates. Further prospective studies are warranted to assess long-term safety, efficacy, and durability.</p>","PeriodicalId":19422,"journal":{"name":"Neuroradiology","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2026-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148977603","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intrasinus solitary fibrous tumor mimicking cerebral venous sinus thrombosis: A case report.","authors":"Toshiki Hayashi, Chiaki Sato, Asako Yamamoto, Yuki Nakamura, Takeshi Uno, Masahiro Shin, Yuko Sasajima, Hiroshi Oba","doi":"10.1007/s00234-026-04191-6","DOIUrl":"https://doi.org/10.1007/s00234-026-04191-6","url":null,"abstract":"<p><p>Solitary fibrous tumors (SFTs), encompassing lesions previously classified as hemangiopericytoma, are rare mesenchymal neoplasms. Intracranial SFTs confined to the dural venous sinus are extremely rare and may mimic cerebral venous sinus thrombosis (CVST). A 76-year-old man presented with impaired consciousness and an elevated D-dimer level. Non-contrast computed tomography and magnetic resonance imaging (MRI) revealed an intraluminal lesion within the posterior superior sagittal sinus. The lesion exhibited mild T2-weighted hyperintensity, without internal flow voids or associated mass effect. CVST was suspected, and anticoagulation therapy was initiated. Imaging follow-up was discontinued after symptomatic improvement. One year later, the patient re-presented with a headache. MRI demonstrated marked enlargement of the lesion, with extension beyond the dura into the adjacent brain parenchyma. Biopsy and subsequent surgical resection confirmed a World Health Organization Central Nervous System grade 1 SFT. Small intrasinus SFTs may closely mimic CVST; therefore, careful imaging follow-up is essential for accurate differentiation.</p>","PeriodicalId":19422,"journal":{"name":"Neuroradiology","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2026-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148970437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Does residual ADP reactivity within the therapeutic range predict intraoperative thromboembolic events during endovascular treatment of intracranial aneurysms?","authors":"Volga Ulaş Ercan, Yılmaz Önal, Murat Velioğlu","doi":"10.1007/s00234-026-04189-0","DOIUrl":"https://doi.org/10.1007/s00234-026-04189-0","url":null,"abstract":"<p><strong>Purpose: </strong>Thromboembolic events remain one of the major complications during endovascular treatment of intracranial aneurysms. Platelet function testing is widely used to identify clopidogrel resistance, yet its role in predicting intraoperative thromboembolic complications among pharmacologically responsive patients remains unclear. This study aimed to evaluate the association between preoperative ADP-induced platelet reactivity and intraoperative thromboembolic events in patients undergoing endovascular aneurysm treatment.</p><p><strong>Methods: </strong>We retrospectively analyzed 196 patients treated for unruptured intracranial aneurysms between March 2017 and March 2020. Patients presenting with subarachnoid hemorrhage or without available preoperative ADP values were excluded. Multiplate platelet function testing was used to measure ADP-induced platelet reactivity. Patients with ADP values > 46 AUC were considered resistant and were switched to ticagrelor or prasugrel before re-testing; resistant cases were excluded from the final analysis. Associations between preoperative ADP values and intraoperative thromboembolic complications were assessed using multivariate logistic regression.</p><p><strong>Results: </strong>The mean age was 55.3 ± 10.9 years, and 72.4% were female. The median preoperative ADP value was 15 (range 0-70). Intraoperative thromboembolic events occurred in 25 patients (12.8%), including material thrombus (6.6%), distal embolism (4.6%), and combined events (1.5%). Female sex was identified as an independent risk factor (OR 3.82, p = 0.045), while patients treated with a flow diverter stent had a lower risk of thromboembolic complications (OR 0.24, p = 0.029). There was no significant association between preoperative ADP reactivity and intraoperative thromboembolic events (p = 0.874).</p><p><strong>Conclusion: </strong>In this cohort of 196 patients with adequate preoperative platelet inhibition, residual ADP-induced platelet reactivity was not associated with the risk of intraoperative thromboembolic complications. These findings suggest that residual ADP reactivity within the therapeutic range has limited value for predicting intraoperative thromboembolic events.</p>","PeriodicalId":19422,"journal":{"name":"Neuroradiology","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2026-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148956292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multiparametric static hybrid ¹⁸F-FET PET/MR for preoperative prediction of TERT promoter mutation in glioblastoma.","authors":"Xiaohong Liang, Leiming Wang, Kai Xiao, Huantong Diao, Meng Zhang, Fengqi Li, Jie Lu","doi":"10.1007/s00234-026-04077-7","DOIUrl":"https://doi.org/10.1007/s00234-026-04077-7","url":null,"abstract":"<p><strong>Purposes: </strong>To determine whether multiparametric hybrid ¹⁸F-FET PET/MRI enables noninvasive prediction of telomerase reverse transcriptase (TERT) promoter mutation in glioblastoma and to assess the incremental value of combined clinical and imaging parameters.</p><p><strong>Methods: </strong>We retrospectively included 220 patients with newly diagnosed glioblastoma at our institution between June 2021 and December 2025. Parametric maps, including ¹⁸F-FET PET, cerebral blood flow (CBF), and apparent diffusion coefficient (ADC), were co-registered with fluid-attenuated inversion recovery (FLAIR) images. Tumor volumes of interest (VOIs) were delineated on FLAIR and transferred to aligned maps for quantitative analysis. Contralateral normal white matter served as the reference region to calculate normalized ADC and CBF values (nADC and nCBF), defined as tumor-to-normal ratios, while PET uptake was expressed as a tumor-to-brain ratio (TBR). Independent predictors were identified using multivariable logistic regression. Diagnostic performance was evaluated using receiver operating characteristic (ROC) analysis with calculation of the area under the curve (AUC).</p><p><strong>Results: </strong>In multivariable logistic regression analysis, age (OR 1.088, 95% CI 1.030-1.148; P = 0.002), TBR_max (OR 2.586, 95% CI 1.126-6.015; P = 0.033), and nADC_max (OR 0.130, 95% CI 0.024-0.700; P = 0.018) were independent predictors of TERT promoter mutations. The combined model incorporating clinical and imaging variables achieved the highest discriminative performance (AUC = 0.893), with a sensitivity of 84.3% and a specificity of 89.4%, outperforming the clinical-only model (AUC = 0.749) and the imaging-only model (AUC = 0.786).</p><p><strong>Conclusion: </strong>Combining age with multiparametric ¹⁸F-FET PET/MRI improves prediction of TERT promoter mutations in glioblastoma and may enable noninvasive preoperative stratification.</p>","PeriodicalId":19422,"journal":{"name":"Neuroradiology","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2026-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148920283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Feasibility and predictors of failure in a distal transradial-first access strategy for endovascular treatment of intracranial aneurysms: A single-center study of 208 cases.","authors":"Kenichi Haraguchi, Ichiro Nakahara, Jun Tanabe, Akiko Hasebe, Kento Sasaki, Kotaro Kihara, Tomoka Katayama, Chisato Fuseya, Riki Tanaka, Yasuhiro Yamada, Fuminari Komatsu, Mai Okubo, Yoko Kato","doi":"10.1007/s00234-026-04169-4","DOIUrl":"https://doi.org/10.1007/s00234-026-04169-4","url":null,"abstract":"<p><strong>Purpose: </strong>To assess the feasibility, procedural success, predictors of failure, and complications associated with the distal transradial approach (dTRA) as first-line endovascular treatment for intracranial aneurysms.</p><p><strong>Methods: </strong>We retrospectively reviewed 208 patients (211 aneurysms) treated between April 2024 and April 2025 in whom dTRA was the default access. Success rates, factors associated with failure, and access-related complications were analyzed.</p><p><strong>Results: </strong>Transradial approach (TRA) puncture success was achieved in 97.1% (202/208) of cases, with an overall success rate of 92.8% (193/208). For dTRA, the puncture success rate was 83.2% (159/191), with treatment success of 95.6% (152/159) after puncture success, comparable to conventional TRA. After successful puncture, procedures through the right internal carotid artery (ICA), left ICA with bovine aortic arch, and bilateral vertebral arteries were all successful, whereas those via the left ICA with a non-bovine aortic arch showed a lower success rate (52/61, 85.2%). In this subgroup, TRA failure was associated with shorter stature (160 cm vs. 151 cm, p=0.039), diabetes mellitus (11.5% vs. 44.4%, p=0.032), smaller brachiocephalic artery-left common carotid artery (BCA-LCCA) angle (19.9° vs. 5.5°, p=0.009), and type III aortic arch (42.3% vs. 88.9%, p=0.013). The optimal BCA-LCCA angle cut-off was 9.4° (area under the curve, 0.78). Access-related complications occurred in 3.4% (7/208) of patients. No symptomatic radial artery occlusion or dissection was observed.</p><p><strong>Conclusion: </strong>TRA with dTRA as a first-line access is feasible and effective. Left ICA access with a non-bovine aortic arch remains technically challenging, particularly in patients with unfavorable factors.</p>","PeriodicalId":19422,"journal":{"name":"Neuroradiology","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2026-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148920268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Altered cortical morphology and structural covariance network in chronic neck and shoulder pain.","authors":"Li Jia, Wenjing Han, Mengqi Li, Yi Zhang, Ke Yang, Yuan Wang","doi":"10.1007/s00234-026-04177-4","DOIUrl":"https://doi.org/10.1007/s00234-026-04177-4","url":null,"abstract":"<p><strong>Purpose: </strong>Despite regional brain structural alterations reported in patients with chronic neck and shoulder pain (CNSP), the specific characteristics of surface-based morphometry (SBM) and structural covariance networks (SCNs) still remain unknown. This study applied cortical morphological and graph theoretical analysis to investigate cortical morphometric alterations and global and nodal network abnormalities in CNSP.</p><p><strong>Methods: </strong>Fifty patients with CNSP and 50 matched healthy controls (HCs) were enrolled in this experiment. All participants underwent structural magnetic resonance imaging and clinical assessments. Cortical thickness (CT), sulcal depth (SD), cortical surface area (CSA), and cortical curvature (CC) of the two groups were calculated and compared. These metrics were then partial-correlated with clinical scales. Additionally, they were extracted from 68 brain regions according to the Desikan-Killiany atlas to construct SCNs for graph theoretical analysis, characterizing alterations in the topological properties in the patient group.</p><p><strong>Results: </strong>Compared with HCs, patients with CNSP exhibited widespread cortical alterations in morphological measures (CT, CSA, SD, and CC), predominantly involving frontal, parietal, and temporal subregions. Moreover, in the CNSP group, the SD of the right inferior parietal lobule was positively correlated with Pain Catastrophizing Scale (PCS) scores. Additionally, the patient group exhibited higher clustering coefficient and longer characteristic path length compared to HCs.</p><p><strong>Conclusions: </strong>Our study demonstrated distinctive alterations of SBM and SCNs in patients with CNSP. These findings provide new insights into the cortical structural and network-level alterations associated with CNSP, contributing to a better understanding of its potential neurobiological basis.</p>","PeriodicalId":19422,"journal":{"name":"Neuroradiology","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2026-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148906893","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Large language models in neuroradiology: an international survey of awareness, applications, and concerns.","authors":"Pranjal Rai, Neetu Soni, Manish Ora, Blake A Kassmeyer, Victoria M Silvera, Amit Agarwal, David F Black, Rajan Jain, Max Wintermark, Girish Bathla","doi":"10.1007/s00234-026-04176-5","DOIUrl":"https://doi.org/10.1007/s00234-026-04176-5","url":null,"abstract":"<p><strong>Objectives: </strong>Large language models (LLMs) are increasingly used in medicine and research, but neuroradiologists' awareness, perceived utility, and concerns about integrity and disclosure remain incompletely characterized. This survey aimed to assess radiologists' awareness and perceptions of LLMs in clinical and research domains.</p><p><strong>Materials and methods: </strong>An anonymous, voluntary SurveyMonkey survey was distributed internationally (October 1, 2024 to March 31, 2025) via neuroradiology society newsletters/membership channels and social media. Categorical variables were summarized as counts and percentages; Likert items were summarized using weighted means and response distributions. Item-level complete-case denominators were reported. Prespecified subgroup analyses used chi-square/Fisher exact tests (categorical) and nonparametric tests (ordinal), with Holm multiplicity control within prespecified multi-item question blocks and within each subgroup factor.</p><p><strong>Results: </strong>A total of 265 respondents started the survey; after exclusions, 209 were included in the analytic sample, of whom 64.6% were male. Awareness of LLMs was high (ChatGPT: 83.3%), but knowledge gaps persisted (14.8% unfamiliar with all listed models; 16.7% misclassified DALL·E as an LLM). Respondents most frequently endorsed bounded, workflow-adjacent clinical applications, including guideline-based recommendations (75.6%) and protocol selection (60.8%), with lower endorsement for image interpretation (22.0%). Concerns were common regarding plagiarism/data fabrication (82.1%), inaccurate or biased outputs (75.8%), and accountability (72.1%), alongside support for AI-detection tools (77.0%) and documentation of LLM use aligned with an example journal policy (73.1%).</p><p><strong>Conclusion: </strong>Survey respondents reported cautious optimism toward LLM integration, favoring workflow-adjacent applications while emphasizing disclosure, oversight, and targeted education.</p>","PeriodicalId":19422,"journal":{"name":"Neuroradiology","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2026-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148897698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Large vessel occlusion in a carotid terminus pure arterial malformation treated with mechanical thrombectomy and early re-occlusion.","authors":"Francesco Biraschi, Carlo Cirelli, Luca Milonia, Francesco Arbia, Francesco Diana","doi":"10.1007/s00234-026-04124-3","DOIUrl":"https://doi.org/10.1007/s00234-026-04124-3","url":null,"abstract":"<p><p>Pure arterial malformations (PAMs) are rare arterial anomalies typically considered incidental, and their role in acute large vessel occlusion is not well defined. We describe a case of acute large vessel occlusion occurring in direct anatomical association with a carotid terminus PAM, treated with mechanical thrombectomy and followed by early selective re-occlusion of the malformed segment. Multimodal imaging and clinical history suggested pre-existing hemodynamic compromise and in situ thrombosis with distal embolization. Mechanical thrombectomy across the PAM segment was technically feasible and resulted in distal reperfusion, but durable patency of the malformed tract was not maintained. This case expands the recognized ischemic spectrum of PAM and suggests that selected morphologically complex lesions may behave as hemodynamically unstable substrates rather than incidental vascular variants.</p>","PeriodicalId":19422,"journal":{"name":"Neuroradiology","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2026-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148897718","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}