Obesity research & clinical practice最新文献

{"title":"Once-weekly semaglutide in heart failure with preserved ejection fraction and obesity: main results from the STEP-HFpEF trial","authors":"Andrew Sindone ⁎, , Mikhail Kosiborod , Steen Z Abildstrøm , Barry A Borlaug , Javed Butler , Søren Rasmussen , Melanie J Davies , G. Kees Hovingh , Dalane W Kitzman , Marie L Lindegaard , Daniél Vega Møller , Sanjiv J Shah , Marianne Bach Treppendahl , Subodh Verma , Mark C Petrie","doi":"10.1016/j.orcp.2024.09.084","DOIUrl":"10.1016/j.orcp.2024.09.084","url":null,"abstract":"","PeriodicalId":19408,"journal":{"name":"Obesity research & clinical practice","volume":"18 5","pages":"Pages S36-S37"},"PeriodicalIF":2.5,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142328175","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The impact of obesity on pregnancy outcomes in women with type 1 and type 2 diabetes across the NSW population","authors":"Xavier XR Rickard ⁎, , Matilda ML Longfield , Sarah SG Glastras","doi":"10.1016/j.orcp.2024.09.069","DOIUrl":"10.1016/j.orcp.2024.09.069","url":null,"abstract":"","PeriodicalId":19408,"journal":{"name":"Obesity research & clinical practice","volume":"18 5","pages":"Pages S29-S30"},"PeriodicalIF":2.5,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142328177","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Integrating health literacy and cultural considerations into a web-based program promoting healthy behaviours in infants","authors":"Danielle Jawad ⁎, , Li Ming Wen , Louise Baur , Chris Rissel , Seema Mihrshahi , Sarah Taki","doi":"10.1016/j.orcp.2024.09.024","DOIUrl":"10.1016/j.orcp.2024.09.024","url":null,"abstract":"","PeriodicalId":19408,"journal":{"name":"Obesity research & clinical practice","volume":"18 5","pages":"Pages S10-S11"},"PeriodicalIF":2.5,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142328225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cycling between chow and high-fat diet: a longitudinal follow-up of diet-induced obesity","authors":"Nhan Ho Trong Pham ⁎, , Mahek Thanki , Ehsan Alvandi , Wilson Wong , Mugdha Joglekar , Anandwardhan Hardikar","doi":"10.1016/j.orcp.2024.09.057","DOIUrl":"10.1016/j.orcp.2024.09.057","url":null,"abstract":"","PeriodicalId":19408,"journal":{"name":"Obesity research & clinical practice","volume":"18 5","pages":"Page S24"},"PeriodicalIF":2.5,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142326339","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Developing a framework to enable clinical health promotion across the healthcare system in Queensland, Australia.","authors":"Jacqueline Walker , Alice Doring , Jacqueline Cotugno , Rebecca Farletti , Lynne McKinlay , Jessica Hardt , Miranda Campbell , Li Kheng Chai ⁎, , Judy Nean , Sjaan Gomersall , Joanna Munro , Robyn Littlewood","doi":"10.1016/j.orcp.2024.09.035","DOIUrl":"10.1016/j.orcp.2024.09.035","url":null,"abstract":"","PeriodicalId":19408,"journal":{"name":"Obesity research & clinical practice","volume":"18 5","pages":"Page S15"},"PeriodicalIF":2.5,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142327788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Uptake of voluntary versus mandatory food labels: A natural experiment in Australia","authors":"Alexandra Jones ⁎, , Damian Maganja , Maria Shahid , Bruce Neal , Simone Pettigrew","doi":"10.1016/j.orcp.2024.09.037","DOIUrl":"10.1016/j.orcp.2024.09.037","url":null,"abstract":"","PeriodicalId":19408,"journal":{"name":"Obesity research & clinical practice","volume":"18 5","pages":"Page S16"},"PeriodicalIF":2.5,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142327790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Characterising support needs of adolescents with obesity participating in a dietary intervention","authors":"Cathy Kwok , Louise A Baur , Eve T House , Kaitlin Day , Megan Gow , Mary Kate Inkster , Sarah Lang , Natalie B Lister , Hiba Jebeile ⁎,","doi":"10.1016/j.orcp.2024.09.046","DOIUrl":"10.1016/j.orcp.2024.09.046","url":null,"abstract":"","PeriodicalId":19408,"journal":{"name":"Obesity research & clinical practice","volume":"18 5","pages":"Pages S19-S20"},"PeriodicalIF":2.5,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142326543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Barriers to accessing a public hospital multidisciplinary weight management program for women with class 3 obesity","authors":"Aman Juneja ⁎, , Kate McBride , Patrick Tran , Milan Piya","doi":"10.1016/j.orcp.2024.09.048","DOIUrl":"10.1016/j.orcp.2024.09.048","url":null,"abstract":"","PeriodicalId":19408,"journal":{"name":"Obesity research & clinical practice","volume":"18 5","pages":"Page S20"},"PeriodicalIF":2.5,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142327303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of different obesity indices with nephrolithiasis in community-dwelling older adults","authors":"Mohamad Gholizade ,&nbsp;Maryam Marzban ,&nbsp;Akram Farhadi ,&nbsp;Hadith Tangestani ,&nbsp;Mehdi Mahmudpour ,&nbsp;Katerina Trajanoska ,&nbsp;Elnaz Shabankari ,&nbsp;Sadaf Rezaie ,&nbsp;Mohammad Mehdi Khaleghi ,&nbsp;Azam Amini ,&nbsp;Iraj Nabipour ,&nbsp;Mohammadreza Kalantarhormozi ,&nbsp;Hadi Emamat ,&nbsp;Afshin Ostovar ,&nbsp;Bagher Larijani ,&nbsp;Amir Hossein Darabi","doi":"10.1016/j.orcp.2024.11.003","DOIUrl":"10.1016/j.orcp.2024.11.003","url":null,"abstract":"<div><h3>Background and objective</h3><div>Obesity has been linked to various conditions, including nephrolithiasis. Given the rising prevalence of both nephrolithiasis and obesity in older adults, this study aimed to examine the association of different obesity-related indices with nephrolithiasis.</div></div><div><h3>Methods</h3><div>This cross-sectional study included 2419 individuals (mean age 69.34 ± 6.40; 51.92 % female) from the Bushehr Elderly Health (BEH) program, a population-based measured using Dual-energy X-ray absorptiometry (DXA), while nephrolithiasis history was assessed through medical records. The associations between obesity-related indices and nephrolithiasis were analyzed using multivariable logistic regression models, adjusted for relevant confounders.</div></div><div><h3>Results</h3><div>Among the 2419 participants, 212 (8.76 %) had a history of nephrolithiasis. In the overall population, only the android-to-gynoid fat mass (FM) ratio was significantly associated with nephrolithiasis (odds ratio [OR] 3.28, 95 % Confidence Interval [CI] 1.06–10.18). In females, the trunk-to-limb FM ratio (OR 2.62, 95 % CI 1.10–6.23) and the visceral adipose index (VAI) (OR 1.092, 95 % CI 1.005–1.187) were associated with nephrolithiasis. In males, only the body adipose index (BAI) was significantly associated with nephrolithiasis (OR 1.082, 95 % CI 1.017–1.151).</div></div><div><h3>Conclusion</h3><div>In this study, the android-to-gynoid FM ratio in the total population, the trunk-to-limb FM ratio and VAI in females, and BAI in males were significantly associated with nephrolithiasis. Monitoring and managing these indices may enhance quality of life for elderly individuals by facilitating early diagnosis of nephrolithiasis and preventing stone formation.</div></div>","PeriodicalId":19408,"journal":{"name":"Obesity research & clinical practice","volume":"18 5","pages":"Pages 371-379"},"PeriodicalIF":2.5,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142770972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of body mass index on semen quality, sperm chromatin integrity and sperm DNA methylation","authors":"Miluse Vozdova,&nbsp;Svatava Kubickova,&nbsp;Vera Kopecka,&nbsp;Jaroslav Sipek,&nbsp;Jiri Rubes","doi":"10.1016/j.orcp.2024.09.276","DOIUrl":"10.1016/j.orcp.2024.09.276","url":null,"abstract":"<div><div>Obesity represents a growing problem due to its impacts on human health and reproduction. In this study, we analysed semen quality, sperm DNA integrity and gene-specific CpG methylation in 116 healthy men from normal population. The men were divided into three groups according to their body mass index (BMI), and their ejaculates were analysed using standard methods, sperm chromatin structure assay (SCSA), methylation next generation sequencing (NGS) and amplicon sequencing. The sperm methylation NGS revealed six significantly differentially methylated regions (DMRs). Using subsequent targeted amplicon sequencing in 116 men, two of the DMRs were proved as differentially methylated in sperm of men with normal BMI vs. BMI ≥ 25. The DMRs were located in the <em>EPHA8</em> and <em>ANKRD11</em> gene. Also, we detected a significant decline in the <em>EPHA8, ANKRD11</em> and <em>CFAP46</em> gene methylation in association with increasing BMI values. The genes <em>EPHA8</em> and <em>ANKRD11</em> are involved in the nervous system and brain development; the <em>CFAP46</em> gene plays a role in a flagellar assembly and is associated with sperm motility. Significantly lower rates of motile and progressive motile sperm were observed in men with BMI ≥ 30. Our results show that excess body weight can modify CpG methylation of specific genes, affect sperm motility, and compromise sperm chromatin integrity. These factors can stand behind the observed reduced fertility in men with obesity. The methylation changes might be transmitted to their offspring through sperm, and become a basis for possible developmental and reproductive issues in the next generation.</div></div>","PeriodicalId":19408,"journal":{"name":"Obesity research & clinical practice","volume":"18 5","pages":"Pages 380-387"},"PeriodicalIF":2.5,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142365969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}