Nutrition and Metabolic Insights最新文献

{"title":"Carrot Juice Consumption Reduces High Fructose-Induced Adiposity in Rats and Body Weight and BMI in Type 2 Diabetic Subjects.","authors":"Malleswarapu Mahesh,&nbsp;Himanshi Pandey,&nbsp;Mooli Raja Gopal Reddy,&nbsp;Prashanti Prabhakaran Sobhana,&nbsp;Damayanti Korrapati,&nbsp;Putcha Uday Kumar,&nbsp;Ayyalasomayajula Vajreswari,&nbsp;Shanmugam Murugaiha Jeyakumar","doi":"10.1177/11786388211014917","DOIUrl":"https://doi.org/10.1177/11786388211014917","url":null,"abstract":"<p><p>Nutritional intervention is a key strategy in the control and management of non-communicable diseases. Here, initially, we evaluated the effects of carrot juice (CJ) on some of the physical and biochemical parameters in rats fed with high-fructose diet, then in type 2 diabetic subjects. For the animal study, weanling male Wistar rats were given control (n = 6) or high fructose (HFr; n = 24) diet for 8 weeks. Then, the HFr group rats were subdivided into 4 groups (n = 6 in each) and continued either on HFr diet or shifted to control diet, with or without CJ (0.3 mg β-carotene) ingestion orally for 8 weeks. At the end, the ingestion of CJ reversed the HFr-induced adiposity (23 ± 1.6 vs 18 ± 1.1, <i>P</i> = .038), hypertriglyceridemia (182 ± 18.2 vs 90 ± 10.5 mg/dL, <i>P</i><0.001), and hyperinsulinemia (81 ± 14.7 vs 40 ± 7.5 µU/mL, <i>P</i> = .014), while increased the retinol levels in liver (240 ± 38.4 vs 492 ± 61.2 µg/g, <i>P</i> = .002) and adipose tissue (1.8 ± 0.09 vs 2.5 ± 0.18 µg/g, <i>P</i> = .026). On the other hand, in the diabetic subjects (7 males and females each, n = 14) compared to their baseline, the daily consumption of 50 mL CJ (~2400 µg β-carotene) for 6 weeks significantly reduced the body weight (69.4 ± 4.13 vs 69.0 ± 4.09 kg, <i>P</i> = .014), BMI (27.4 ± 1.07 vs 27.2 ± 1.06 kg/m², <i>P</i> = .007), and fat% (33.4 ± 1.87 vs 31.9 ± 2.13, <i>P</i> = .029) with an increase in plasma β-carotene levels (0.21 ± 0.045 vs 0.45 ± 0.089 µmol/L, <i>P</i> = .044). Although CJ increased the glucose (145 ± 10.4 vs 165 ± 11.4 mg/dL, <i>P</i> = .039), insulin, and glycated hemoglobin levels remained unaltered. In conclusion, the consumption of carrot juice reversed the HFr-induced metabolic abnormalities in a rat model and decreased body weight and BMI of diabetic subjects.</p>","PeriodicalId":19396,"journal":{"name":"Nutrition and Metabolic Insights","volume":"14 ","pages":"11786388211014917"},"PeriodicalIF":1.7,"publicationDate":"2021-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/11786388211014917","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39276464","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Early Exposure is Necessary for the Lifespan Extension Effects of Cocoa in <i>C. elegans</i>.","authors":"Mihiri Munasinghe,&nbsp;Abdullah Almotayri,&nbsp;Jency Thomas,&nbsp;Deniz Heydarian,&nbsp;Markandeya Jois","doi":"10.1177/11786388211029443","DOIUrl":"https://doi.org/10.1177/11786388211029443","url":null,"abstract":"<p><strong>Background: </strong>We previously showed that cocoa, a rich source of polyphenols improved the age-associated health and extended the lifespan in <i>C. elegans</i> when supplemented starting from L1 stage.</p><p><strong>Aim: </strong>In this study, we aimed to find out the effects of timing of cocoa exposure on longevity improving effects and the mechanisms and pathways involved in lifespan extension in <i>C. elegans</i>.</p><p><strong>Methods: </strong>The standard <i>E. coli</i> OP50 diet of wild type <i>C. elegans</i> was supplemented with cocoa powder starting from different larval stages (L1, L2, L3, and L4) till the death, from L1 to adult day 1 and from adult day 1 till the death. For mechanistic studies, different mutant strains of <i>C. elegans</i> were supplemented with cocoa starting from L1 stage till the death. Survival curves were plotted, and mean lifespan was reported.</p><p><strong>Results: </strong>Cocoa exposure starting from L1 stage till the death and till adult day 1 significantly extended the lifespan of worms. However, cocoa supplementation at other larval stages as well as at adulthood could not extend the lifespan, instead the lifespan was significantly reduced. Cocoa could not extend the lifespan of <i>daf-16, daf-2, sir-2.1</i>, and <i>clk-1</i> mutants.</p><p><strong>Conclusion: </strong>Early-start supplementation is essential for cocoa-mediated lifespan extension which is dependent on insulin/IGF-1 signaling pathway and mitochondrial respiration.</p>","PeriodicalId":19396,"journal":{"name":"Nutrition and Metabolic Insights","volume":"14 ","pages":"11786388211029443"},"PeriodicalIF":1.7,"publicationDate":"2021-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/11786388211029443","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39206658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between Physical Activity and Cognitive Function among the Elderly in the Health and Social Centers in Kenitra, Rabat, and Sidi Kacem City (Morocco).","authors":"Abdeljalil Talhaoui,&nbsp;Youssef Aboussaleh,&nbsp;Ahmed Ahami,&nbsp;Rachid Sbaibi,&nbsp;Naima Agoutim,&nbsp;Fatima Zohra Rouim,&nbsp;Khadija Karjouh","doi":"10.1177/11786388211026758","DOIUrl":"https://doi.org/10.1177/11786388211026758","url":null,"abstract":"<p><strong>Objective: </strong>The aim of this study was to determine the link between the physical activity (PA) and cognitive function among the elderly in the health and social centers in Kenitra, Rabat, and Sidi Kacem city (Morocco).</p><p><strong>Materials and methods: </strong>This study was conducted among 172 elderly (56.4% men) aged above 60 years (67.53 ± 7.53) in the health and social centers in Kenitra, Rabat, and Sidi Kacem city (Morocco). Cognitive functions were assessed by the Mini-Mental State Examination (MMSE) (Normal: MMSE's score >24 and cognitive impairment (CI): MMSE's score ⩽ 24). The physical activity (PA) was evaluated using the GPAQ (Global Physical Activity Questionnaire), ranking the elderly by high, moderate, and limited level of PA. The binary logistic regression was performed by the cognitive function (dependent variable), and PA level (independent variable).</p><p><strong>Results: </strong>The elderly people with cognitive impairment (MMSE score <24 tend to practice less walking and cycling activities <b>(</b> <i>P</i> <i>=</i> <i>.005</i>). However no difference was found between normal and cognitively impaired subjects for all other subtypes of PA (<i>P</i> > .05). The binary logistic regression adjusted for gender, education, profession, pension, depression, and nutritional status reveled that only the moderate level of PA was a protective factor against cognitive impairment compared to limited level (ORa = 0.136, 95% CI: 0.04-0.41) (ORa: Adjusted Odd Ratio; 95% CI: 95% of Confidence Interval).</p><p><strong>Conclusion: </strong>Our finding demonstrates that moderate PA specially walking or cycling is associated with lower risk of cognitive impairment. This indicates that a regular practice of walking or cycling as PA can play an important role for cognitive impairment prevention. And the necessity for further researches to more understands this association.</p>","PeriodicalId":19396,"journal":{"name":"Nutrition and Metabolic Insights","volume":"14 ","pages":"11786388211026758"},"PeriodicalIF":1.7,"publicationDate":"2021-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/11786388211026758","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39196712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"TSH Mediated the Effect of Iodized Salt on Child Cognition in a Randomized Clinical Trial.","authors":"Husein Mohammed,&nbsp;Grace S Marquis,&nbsp;Frances Aboud,&nbsp;Karim Bougma,&nbsp;Aregash Samuel","doi":"10.1177/11786388211025352","DOIUrl":"https://doi.org/10.1177/11786388211025352","url":null,"abstract":"<p><strong>Objectives: </strong>This study examines the hormonal mediators of the effect of iodized salt in pregnancy on child cognition.</p><p><strong>Methods: </strong>Sixty districts across 6 zones in the Amhara region of Ethiopia were randomly allocated to a control or intervention arm of early market access to iodized salt. Twenty-two villages per arm were randomly selected for this sub-study. A total of 1220 pregnant women who conceived after the intervention began were enrolled and assessed for their iodine and iron status. Data were collected once on the household socio-demographic status and iodized salt use, and maternal urinary iodine during pregnancy. Then, infants' diet, urinary iodine level, cognitive development (Bayley III), serum hormonal levels, iron status, and inflammation markers were measured between 2 and 13 months of age.</p><p><strong>Results: </strong>The median maternal urinary iodine concentration was adequate and significantly higher in the intervention mothers than that of the controls (163 vs 121 µg/L, <i>P</i> < .0001). Intervention children compared to the control children had lower thyroid-stimulating hormone (TSH) (mean: 2.4 ± 1.0 µIU/mL vs 2.7 ± 1.0 µIU/mL, effect size = 0.18, <i>P</i> < .01) and thyroglobulin (Tg) (41.6 ± 1.0 ng/mL vs 45.1 ± 1.0 ng/mL, effect size = 0.14, <i>P</i> < .05). There was an interaction between the intervention and iron stores such that cognition was higher with iron (effect size = 0.28, 100 vs 94 IQ points). TSH was a partial mediator (12%) of the effect of the intervention on child cognition (Sobel z-score = 2.1 ± 0.06, <i>P</i> < .05).</p><p><strong>Conclusion: </strong>TSH partially mediated the effect of the iodized salt intervention on child cognition.</p>","PeriodicalId":19396,"journal":{"name":"Nutrition and Metabolic Insights","volume":"14 ","pages":"11786388211025352"},"PeriodicalIF":1.7,"publicationDate":"2021-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/11786388211025352","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39142319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Magnitude, Trends, and Determinants of Iodized Salt Availability among Households in Ethiopia: Analysis of Ethiopian Demographic and Health Surveys (2000-2016).","authors":"Amare Abera Tareke,&nbsp;Taddese Alemu Zerfu","doi":"10.1177/11786388211025342","DOIUrl":"https://doi.org/10.1177/11786388211025342","url":null,"abstract":"<p><strong>Background: </strong>Iodine deficiency causes various health problems such as mental defects, goiter, reproductive damage, hypo and hyperthyroidism, stillbirth, abortion, congenital abnormalities, cretinism, mental retardation, muscle anomalies, and reduced work output. Although the adverse effects on health and socio-economic development are well known, they persisted as a public health problem worldwide. Salt iodization is recommended as a simple cost-effective method to prevent iodine deficiency disorders. This study aimed to determine the magnitude, trends, and determinants of iodized salt availability in the household in Ethiopia.</p><p><strong>Methods: </strong>The current study used the Ethiopian Demographic and Health Surveys conducted from 2000 to 2016 with a total of 57 939 households. Descriptive statistics were performed on selected background characteristics to provide an overall picture of the sample after considering sample weights. To ensure the representativeness of the sample we applied a complex sample design considering household weights, primary sampling units, and the strata associated with it. The Cochran-Armitage test was performed to assess the trend of iodized salt availability in the household. Multivariate logistic regression was used to determine the association between the dependent variable and independent variables. A significance level of .05 was chosen for all analyses.</p><p><strong>Results: </strong>The magnitude of iodized salt availability in the household was 28.45% in 2000, 54.34% in 2005, 15.42% in 2011, and 89.28% in 2016. Iodized salt availability increased from 28.45% [95% CI: 27.69-29.21] in 2000 to 89.28% [95% CI: 88.79-89.75] in 2016. Despite the decline from 2005 to 2011 in the percentage of households with iodized salt, overall, there was a significant increment from 2000 to 2016 in Ethiopia (<i>P</i>-value <.001). There were differences in the status of salt iodization in the administrative region, wealth, family size, and ownership of radio or television.</p><p><strong>Conclusion: </strong>Remarkable progress has been made in Ethiopia regarding iodized salt availability in recent years. Besides the current efforts to achieve universal salt iodization, future interventions should prioritize specific groups like those with lower socioeconomic status and geographic areas with lower availability of iodized salt in the household.</p>","PeriodicalId":19396,"journal":{"name":"Nutrition and Metabolic Insights","volume":"14 ","pages":"11786388211025342"},"PeriodicalIF":1.7,"publicationDate":"2021-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/11786388211025342","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39142780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Protein Intake and Cognitive Function in Older Adults: A Systematic Review and Meta-Analysis.","authors":"Hélio José Coelho-Júnior,&nbsp;Riccardo Calvani,&nbsp;Francesco Landi,&nbsp;Anna Picca,&nbsp;Emanuele Marzetti","doi":"10.1177/11786388211022373","DOIUrl":"https://doi.org/10.1177/11786388211022373","url":null,"abstract":"<p><strong>Introduction: </strong>The present study investigated the association between protein intake and cognitive function in older adults.</p><p><strong>Methods: </strong>We performed a literature search with no restriction on publication year in MEDLINE, SCOPUS, CINAHL, AgeLine from inception up to October 2020. Observational studies that investigated as a primary or secondary outcome the association of protein intake and cognitive function in older adults aged ⩾60 years were included.</p><p><strong>Results: </strong>Nine cross-sectional studies that investigated a total of 4929 older adults were included in the qualitative analysis. Overall cognitive function was examined in 6 studies. Four investigations reported null associations and 2 studies found that older adults with a high protein intake had higher global cognitive function than their counterparts. Results from the meta-analysis suggested that there were no significant associations between protein consumption and global cognitive function in older adults, regardless of gender. Three studies investigated other cognitive domains. Memory and protein intake were significantly and positively correlated in all studies. In addition, visuospatial, verbal fluency, processing speed, and sustained attention were positively associated with protein consumption in 1 study each.</p><p><strong>Conclusion: </strong>No significant associations between protein intake and global cognitive function were observed in neither qualitative nor quantitative analyses. The association between protein consumption with multiple other cognitive domains were also tested. As a whole, 3 studies reported a positive and significant association between high protein intake and memory, while 1 study observed a significant and positive association with visuospatial, verbal fluency, processing speed, and sustained attention.</p>","PeriodicalId":19396,"journal":{"name":"Nutrition and Metabolic Insights","volume":"14 ","pages":"11786388211022373"},"PeriodicalIF":1.7,"publicationDate":"2021-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/11786388211022373","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39097034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fish Consumption: A Review of Its Effects on Metabolic and Hormonal Health.","authors":"Carlos O Mendivil","doi":"10.1177/11786388211022378","DOIUrl":"10.1177/11786388211022378","url":null,"abstract":"<p><p>Dietary habits are a major determinant of the risk of chronic disease, particularly metabolic and endocrine disorders. Fish as a food group are a unique source of nutrients with metabolic and hormonal importance including omega-3 fatty acids, iodine, selenium, vitamin D, taurine and carnitine. Fish are also a source of high quality protein and have in general low caloric density. The impact of these nutrients on cardiovascular risk has been extensively reviewed, but the impact of fish on the broader field of endocrine and metabolic health is sometimes not sufficiently appreciated. This article aimed to summarize the impact the effect of regular fish consumption on conditions like the metabolic syndrome, obesity, diabetes, hypothyroidism, polycystic ovary syndrome and the menopausal transition, which are in and of themselves significant causes of morbidity and mortality worldwide. The review revealed that scientific evidence from food science, translational research, epidemiologic studies and interventional trials shows that regular fish consumption has a positive impact on thyroid homeostasis, facilitates maintenance of a healthy body weight, reduces the magnitude of age-associated increases in blood pressure, improves glucose homeostasis helping prevent diabetes and the metabolic syndrome, and has a positive impact on muscle mass preservation among the elderly. These effects are mediated by multiple mechanisms, only some of which have been identified. For most of these effects it holds true that the potential benefits are more substantial when baseline fish consumption is low.</p>","PeriodicalId":19396,"journal":{"name":"Nutrition and Metabolic Insights","volume":"14 ","pages":"11786388211022378"},"PeriodicalIF":2.3,"publicationDate":"2021-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/eb/70/10.1177_11786388211022378.PMC8182174.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39097035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vitamin D Deficiency in Children and Adolescents: Role of Puberty and Obesity on Vitamin D Status.","authors":"Hedyeh Saneifard,&nbsp;Marjan Shakiba,&nbsp;Ali Sheikhy,&nbsp;Leila Baniadam,&nbsp;Fatemeh Abdollah Gorji,&nbsp;Aida Fallahzadeh","doi":"10.1177/11786388211018726","DOIUrl":"https://doi.org/10.1177/11786388211018726","url":null,"abstract":"<p><strong>Background: </strong>Vitamin D deficiency is common among children and adolescents and can be affected by several factors such as puberty and obesity.</p><p><strong>Objective: </strong>The aim of this study was to evaluate vitamin D status in children and adolescents and to analyse the influence of puberty and obesity on its level.</p><p><strong>Method: </strong>A cross-sectional study was carried-out, in which clinical and biochemical data were gathered from 384 healthy children and adolescents between May 2019 to May 2020.</p><p><strong>Results: </strong>220 females and 164 males were enrolled (aged 7-16 years; mean ± SD: 11 ± 2.5). Vitamin D deficiency was found in 49% of the total cases and was significantly more prevalent in females than males (33.1% in female; 15.9% in male, <i>P</i> < .001). Mean vitamin D level was lower in obese children compared with non-obese (<i>P</i> < .001). Non-obese group had significantly higher levels of vitamin D in Tanner stage IV of puberty than obese individuals (20.1 ± 17.0 vs 5.4 ± 2.0) (<i>P</i> = .03). Vitamin D levels were significantly lower in females than males only in Tanner stage II (12.3 ± 9.0 vs 19.6 ± 16.6) (<i>P</i> = .005). The lowest level of Vitamin D was in Tanner stage Ⅳ-Ⅴ in boys and in Tanner stage Ⅱ-Ⅲ in girls (<i>P</i> < .001).</p><p><strong>Conclusion: </strong>Puberty is an additional risk factor for vitamin D deficiency especially in girls and obese children. This increased risk, together with the fact that most important time for building a proper skeleton is during childhood and adolescent, makes it essential to monitor vitamin D in these age groups.</p>","PeriodicalId":19396,"journal":{"name":"Nutrition and Metabolic Insights","volume":"14 ","pages":"11786388211018726"},"PeriodicalIF":1.7,"publicationDate":"2021-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/11786388211018726","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39007194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Knowledge of Vegetarian and Nonvegetarian Peruvian Dietitians about Vegetarianism at Different Stages of Life.","authors":"Jacksaint Saintila,&nbsp;Yaquelin E Calizaya-Milla,&nbsp;David J Javier-Aliaga","doi":"10.1177/1178638821997123","DOIUrl":"https://doi.org/10.1177/1178638821997123","url":null,"abstract":"<p><strong>Background: </strong>The vegetarian diet continues to gain recognition and popularity among people; however, few studies have considered the level of knowledge of professional dietitians about this dietary pattern.</p><p><strong>Objective: </strong>This study aimed to compare the level of knowledge of vegetarian and nonvegetarian Peruvian dietitians regarding vegetarianism at different life stages.</p><p><strong>Methods: </strong>A cross-sectional study was carried out. An online questionnaire based on the recommendations of the current dietary guidelines was administered to more than 400 registered dietitians. Of which, a total of 179 decided to participate in the study: 72 vegetarians and 107 nonvegetarians. The data were analyzed using the chi-square test, considering a significance level of 5%.</p><p><strong>Results: </strong>Women represented the largest proportion of the sample. The participants demonstrated a complete and exhaustive knowledge of the definition of vegetarian diets. Regarding the risks and benefits associated with vegetarianism, the largest proportion of those who got the correct answers were vegetarians. The percentage of correct answers selected for both groups regarding the critical nutrients were less than 50%. Only 17.6% identified the correct answer regarding the risk of eating disorders of vegetarianism.</p><p><strong>Conclusions: </strong>Dietitians did not demonstrate complete and comprehensive knowledge of the critical nutrients of vegetarianism and lack information on the risks of eating disorders from the vegetarian diet.</p>","PeriodicalId":19396,"journal":{"name":"Nutrition and Metabolic Insights","volume":"14 ","pages":"1178638821997123"},"PeriodicalIF":1.7,"publicationDate":"2021-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/1178638821997123","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39066322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Factors Associated with Intended Postpartum OGTT Uptake and Willingness to Receive Preventive Behavior Support to Reduce Type 2 Diabetes Risk Among Women with Gestational Diabetes in Singapore: An Exploratory Study.","authors":"Sumali S Hewage,&nbsp;Su Aw,&nbsp;Claudia Chi,&nbsp;Joanne Yoong","doi":"10.1177/11786388211016827","DOIUrl":"https://doi.org/10.1177/11786388211016827","url":null,"abstract":"<p><strong>Aim: </strong>To assess and explore the factors affecting willingness to undergo an early postpartum oral glucose tolerance test (OGTT) and receive postpartum lifestyle modification assistance.</p><p><strong>Methods: </strong>An explanatory sequential mixed-method design was used. A prenatal cross-sectional survey questionnaire (n = 216) was given to women diagnosed with GDM in a tertiary health institution in Singapore and followed up with postpartum semi-structured interviews (n = 30). Multivariate logistic regression and thematic analysis were conducted before merging the findings.</p><p><strong>Results: </strong>Despite universal GDM education, fewer than 75% intended to take the OGTT postpartum, and only 63% felt it was very important. The plan to take the OGTT postpartum was positively associated with a prenatal care provider's specific recommendation. In contrast, Malay women were less likely to take the test. Most women interpreted a care provider's recommendation as implying standard practice, which encouraged intended and actual compliance with testing after giving birth. The perception of moderate to high T2DM risk in the following decade, and subsidized prenatal care, and plan to take the OGTT postpartum were positively associated with willingness to receive postpartum lifestyle behavior support. A mobile application was the preferred method to receive support.</p><p><strong>Conclusions: </strong>In the early postpartum period, women with a history of GDM were willing to receive measures to reduce T2DM risk, primarily if it was under the supervision and recommendation of a care provider. A carefully designed but simple postpartum lifestyle intervention incorporating these preferences that can be integrated into mainstream diabetes prevention programs is warranted.</p>","PeriodicalId":19396,"journal":{"name":"Nutrition and Metabolic Insights","volume":"14 ","pages":"11786388211016827"},"PeriodicalIF":1.7,"publicationDate":"2021-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/11786388211016827","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38936851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}