Hedyeh Saneifard, Marjan Shakiba, Ali Sheikhy, Leila Baniadam, Fatemeh Abdollah Gorji, Aida Fallahzadeh
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Vitamin D deficiency was found in 49% of the total cases and was significantly more prevalent in females than males (33.1% in female; 15.9% in male, <i>P</i> < .001). Mean vitamin D level was lower in obese children compared with non-obese (<i>P</i> < .001). Non-obese group had significantly higher levels of vitamin D in Tanner stage IV of puberty than obese individuals (20.1 ± 17.0 vs 5.4 ± 2.0) (<i>P</i> = .03). Vitamin D levels were significantly lower in females than males only in Tanner stage II (12.3 ± 9.0 vs 19.6 ± 16.6) (<i>P</i> = .005). The lowest level of Vitamin D was in Tanner stage Ⅳ-Ⅴ in boys and in Tanner stage Ⅱ-Ⅲ in girls (<i>P</i> < .001).</p><p><strong>Conclusion: </strong>Puberty is an additional risk factor for vitamin D deficiency especially in girls and obese children. This increased risk, together with the fact that most important time for building a proper skeleton is during childhood and adolescent, makes it essential to monitor vitamin D in these age groups.</p>","PeriodicalId":19396,"journal":{"name":"Nutrition and Metabolic Insights","volume":"14 ","pages":"11786388211018726"},"PeriodicalIF":2.3000,"publicationDate":"2021-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/11786388211018726","citationCount":"7","resultStr":"{\"title\":\"Vitamin D Deficiency in Children and Adolescents: Role of Puberty and Obesity on Vitamin D Status.\",\"authors\":\"Hedyeh Saneifard, Marjan Shakiba, Ali Sheikhy, Leila Baniadam, Fatemeh Abdollah Gorji, Aida Fallahzadeh\",\"doi\":\"10.1177/11786388211018726\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Vitamin D deficiency is common among children and adolescents and can be affected by several factors such as puberty and obesity.</p><p><strong>Objective: </strong>The aim of this study was to evaluate vitamin D status in children and adolescents and to analyse the influence of puberty and obesity on its level.</p><p><strong>Method: </strong>A cross-sectional study was carried-out, in which clinical and biochemical data were gathered from 384 healthy children and adolescents between May 2019 to May 2020.</p><p><strong>Results: </strong>220 females and 164 males were enrolled (aged 7-16 years; mean ± SD: 11 ± 2.5). Vitamin D deficiency was found in 49% of the total cases and was significantly more prevalent in females than males (33.1% in female; 15.9% in male, <i>P</i> < .001). Mean vitamin D level was lower in obese children compared with non-obese (<i>P</i> < .001). Non-obese group had significantly higher levels of vitamin D in Tanner stage IV of puberty than obese individuals (20.1 ± 17.0 vs 5.4 ± 2.0) (<i>P</i> = .03). Vitamin D levels were significantly lower in females than males only in Tanner stage II (12.3 ± 9.0 vs 19.6 ± 16.6) (<i>P</i> = .005). The lowest level of Vitamin D was in Tanner stage Ⅳ-Ⅴ in boys and in Tanner stage Ⅱ-Ⅲ in girls (<i>P</i> < .001).</p><p><strong>Conclusion: </strong>Puberty is an additional risk factor for vitamin D deficiency especially in girls and obese children. 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引用次数: 7
摘要
背景:维生素D缺乏症在儿童和青少年中很常见，可能受到青春期和肥胖等多种因素的影响。目的:本研究的目的是评估儿童和青少年的维生素D水平，并分析青春期和肥胖对其水平的影响。方法:采用横断面研究方法，收集2019年5月至2020年5月384例健康儿童青少年的临床及生化资料。结果:纳入220名女性和164名男性(年龄7-16岁;平均值±SD: 11±2.5)。在所有病例中，有49%的人缺乏维生素D，女性的患病率明显高于男性(女性为33.1%;男性15.9%，P < 0.001)。肥胖儿童的平均维生素D水平低于非肥胖儿童(P < 0.001)。非肥胖组青春期Tanner期维生素D水平显著高于肥胖组(20.1±17.0 vs 5.4±2.0)(P = 0.03)。维生素D水平仅在Tanner II期女性明显低于男性(12.3±9.0 vs 19.6±16.6)(P = 0.005)。男孩Tanner期Ⅳ~Ⅴ、女孩Tanner期Ⅱ~Ⅲ维生素D水平最低(P < 0.001)。结论:青春期是维生素D缺乏的另一个危险因素，尤其是在女孩和肥胖儿童中。由于风险增加，再加上儿童和青少年是骨骼发育最重要的时期，因此监测这些年龄段的维生素D至关重要。
Vitamin D Deficiency in Children and Adolescents: Role of Puberty and Obesity on Vitamin D Status.
Background: Vitamin D deficiency is common among children and adolescents and can be affected by several factors such as puberty and obesity.
Objective: The aim of this study was to evaluate vitamin D status in children and adolescents and to analyse the influence of puberty and obesity on its level.
Method: A cross-sectional study was carried-out, in which clinical and biochemical data were gathered from 384 healthy children and adolescents between May 2019 to May 2020.
Results: 220 females and 164 males were enrolled (aged 7-16 years; mean ± SD: 11 ± 2.5). Vitamin D deficiency was found in 49% of the total cases and was significantly more prevalent in females than males (33.1% in female; 15.9% in male, P < .001). Mean vitamin D level was lower in obese children compared with non-obese (P < .001). Non-obese group had significantly higher levels of vitamin D in Tanner stage IV of puberty than obese individuals (20.1 ± 17.0 vs 5.4 ± 2.0) (P = .03). Vitamin D levels were significantly lower in females than males only in Tanner stage II (12.3 ± 9.0 vs 19.6 ± 16.6) (P = .005). The lowest level of Vitamin D was in Tanner stage Ⅳ-Ⅴ in boys and in Tanner stage Ⅱ-Ⅲ in girls (P < .001).
Conclusion: Puberty is an additional risk factor for vitamin D deficiency especially in girls and obese children. This increased risk, together with the fact that most important time for building a proper skeleton is during childhood and adolescent, makes it essential to monitor vitamin D in these age groups.
期刊介绍：
Nutrition and Metabolic Insights is a peer-reviewed, open-access online journal focusing on all aspects of nutrition and metabolism. This encompasses nutrition, including the biochemistry of metabolism, exercise and associated physical processes and also includes clinical articles that relate to metabolism, such as obesity, lipidemias and diabetes. It includes research at the molecular, cellular and organismal levels. This journal welcomes new manuscripts for peer review on the following topics: Nutrition, including the biochemistry of metabolism, Exercise and associated physical processes, Clinical articles that relate to metabolism, such as obesity, lipidemias and diabetes, Research at the molecular, cellular and organismal levels, Other areas of interest include gene-nutrient interactions, the effects of hormones, models of metabolic function, macronutrient interactions, outcomes of changes in diet, and pathophysiology.
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