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Multifaceted roles of SUMO in DNA metabolism SUMO 在 DNA 代谢中的多方面作用
IF 3.7 3区 生物学
Nucleus Pub Date : 2024-09-17 DOI: 10.1080/19491034.2024.2398450
Yee Mon Thu
{"title":"Multifaceted roles of SUMO in DNA metabolism","authors":"Yee Mon Thu","doi":"10.1080/19491034.2024.2398450","DOIUrl":"https://doi.org/10.1080/19491034.2024.2398450","url":null,"abstract":"Sumoylation, a process in which SUMO (small ubiquitin like modifier) is conjugated to target proteins, emerges as a post-translational modification that mediates protein−protein interactions, prote...","PeriodicalId":19392,"journal":{"name":"Nucleus","volume":null,"pages":null},"PeriodicalIF":3.7,"publicationDate":"2024-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142261520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Deciphering the intrinsically disordered characteristics of the FG-Nups through the lens of polymer physics. 从聚合物物理学的角度解读 FG-Nups 固有的无序特性。
IF 3.7 3区 生物学
Nucleus Pub Date : 2024-09-16 DOI: 10.1080/19491034.2024.2399247
Atsushi Matsuda,Abdullah Mansour,Mohammad R K Mofrad
{"title":"Deciphering the intrinsically disordered characteristics of the FG-Nups through the lens of polymer physics.","authors":"Atsushi Matsuda,Abdullah Mansour,Mohammad R K Mofrad","doi":"10.1080/19491034.2024.2399247","DOIUrl":"https://doi.org/10.1080/19491034.2024.2399247","url":null,"abstract":"The nuclear pore complex (NPC) is a critical gateway regulating molecular transport between the nucleus and cytoplasm. It allows small molecules to pass freely, while larger molecules require nuclear transport receptors to traverse the barrier. This selective permeability is maintained by phenylalanine-glycine-rich nucleoporins (FG-Nups), intrinsically disordered proteins that fill the NPC's central channel. The disordered and flexible nature of FG-Nups complicates their spatial characterization with conventional structural biology techniques. To address this challenge, polymer physics offers a valuable framework for describing FG-Nup behavior, reducing their complex structures to a few key parameters. In this review, we explore how polymer physics models FG-Nups using these parameters and discuss experimental efforts to quantify them in various contexts, providing insights into the conformational properties of FG-Nups.","PeriodicalId":19392,"journal":{"name":"Nucleus","volume":null,"pages":null},"PeriodicalIF":3.7,"publicationDate":"2024-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142261523","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nuclear bodies: concentrating at an aqueous site, with momentum. 核体：在水体中集中，具有动量。
IF 3.7 3区 生物学
Nucleus Pub Date : 2024-09-16 DOI: 10.1080/19491034.2024.2404677
Ling-Ling Chen,Erica Larschan,A Gregory Matera,Amy Strom,Thoru Pederson
{"title":"Nuclear bodies: concentrating at an aqueous site, with momentum.","authors":"Ling-Ling Chen,Erica Larschan,A Gregory Matera,Amy Strom,Thoru Pederson","doi":"10.1080/19491034.2024.2404677","DOIUrl":"https://doi.org/10.1080/19491034.2024.2404677","url":null,"abstract":"The second FASEB conference on Nuclear Bodies: Hubs of Genome Activity was held June 2-7, 2024, at Niagara Falls, NY. The central theme was how these protein and RNA-protein complexes that are situated in the nucleus outside the genome support and regulate gene expression. Topics included their relevance to disease, especially cancer, their molecular dynamics, and their phase separation transition properties. The meeting included numerous trainees as speakers and session chairs, hosted a memorable Keynote talk on diversity, and a vibrant career development session.","PeriodicalId":19392,"journal":{"name":"Nucleus","volume":null,"pages":null},"PeriodicalIF":3.7,"publicationDate":"2024-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142261521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Potential of Solid Waste from Palm Oil as Fuel for Steam Power Plants in Palm Oil Factories 棕榈油固体废物作为棕榈油工厂蒸汽发电厂燃料的潜力
IF 3.7 3区 生物学
Nucleus Pub Date : 2024-05-21 DOI: 10.37010/nuc.v5i1.1542
Dino Erivianto, Ahmad Dani
{"title":"Potential of Solid Waste from Palm Oil as Fuel for Steam Power Plants in Palm Oil Factories","authors":"Dino Erivianto, Ahmad Dani","doi":"10.37010/nuc.v5i1.1542","DOIUrl":"https://doi.org/10.37010/nuc.v5i1.1542","url":null,"abstract":"This research aims to analyze the potential electric energy contained in the by-products and processed waste of palm oil. Biomass derived from palm oil by-products can serve as an alternative source of energy, with potential calorific value to generate electricity from boilers or as renewable energy. While solid waste from palm oil by-products is commonly utilized as boiler fuel and fertilizer, it holds promise as a renewable energy source in its entirety. The research process includes problem identification, formulation, determination of research objectives, literature review, field surveys, primary data collection through observation and interviews, data analysis, and presentation of research results. Field observations from several visited palm oil mills reveal that solid waste by-products typically consist of 5-7% shell, 11-14% fiber, and 20-22% Empty Fruit Bunches (EFB) per ton of processed Fresh Fruit Bunches (FFB). Considering the maximum electricity requirement for processing 30 tons/hour and the potential electrical energy contained in each waste type, utilizing fiber waste alone as boiler fuel is sufficient, offering a potential electrical energy of 542.1 kW. Any excess electrical power generated (580 kW) by the boiler can be sourced from shell waste, enabling surplus electricity to be sold to external parties. With the surplus electrical power estimated at 130 – 70 kW/hour, operating for 20 hours per day yields a surplus of 1.4 – 2.6 MW/day from processing. The calorific value of solid palm oil waste is notably affected by its moisture content. Proper management of fiber waste utilization can effectively fulfill the energy needs of palm oil mills. Additionally, there is potential to sell approximately 648 – 686 kW of electrical energy externally, derived from shell waste and EFB.","PeriodicalId":19392,"journal":{"name":"Nucleus","volume":null,"pages":null},"PeriodicalIF":3.7,"publicationDate":"2024-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141114854","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Analisis Bibliometrik Vector Error Correction Model 文献分析向量误差修正模型
IF 3.7 3区 生物学
Nucleus Pub Date : 2024-05-21 DOI: 10.37010/nuc.v5i1.1541
Putri Aura Santika, Dewi Retno Sari Saputro, N. A. Kurdhi
{"title":"Analisis Bibliometrik Vector Error Correction Model","authors":"Putri Aura Santika, Dewi Retno Sari Saputro, N. A. Kurdhi","doi":"10.37010/nuc.v5i1.1541","DOIUrl":"https://doi.org/10.37010/nuc.v5i1.1541","url":null,"abstract":"Analisis Bibliometrik adalah teknik kuantitatif untuk menganalisis literatur ilmiah hal ini mencakup penghitungan jumlah publikasi, analisis sitasi, dan penemuan tren penelitian. Analisis bibliometrik berguna dalam memahami serta mengklasifikasikan dokumen yang diterbitkan dan bisa menjelaskan perkembangan yang sedang berlangsung serta penelitian baru terkait topik yang ditentukan. Alat pemetaan yang dapat digunakan adalah VOSviewer untuk memvisualisasikan peta grafis bibliometrik. Artikel ini bertujuan memberikan arah atau landasan terhadap penelitian selanjutnya terkait vector error correction model (VECM). Penelitian ini merupakan studi pustaka dengan menggunakan pengumpulan data bibliometrik yang berfokus pada topik terkait vector error correction model (VECM), langkah penelitian yang dilakukan adalah menentukan kata kunci pencarian, penelitian pencarian awal, penyempurnaan pencarian, penyusunan statistik data, dan analisis data. Data diperoleh dari laman Scopus dalam rentang tahun 2009 hingga 2023. Dari data tersebut diperoleh publikasi terbanyak pada tahun 2023 sejumlah 585 publikasi. Setelah dilakukan visualisasi menggunakan VOSviewer diketahui berbagai istilah pada vector error correction model (VECM) yang sering muncul dan berkaitan dengan variabel lainnya.","PeriodicalId":19392,"journal":{"name":"Nucleus","volume":null,"pages":null},"PeriodicalIF":3.7,"publicationDate":"2024-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141116150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nuclear functions regulated by the VRK1 kinase. 受 VRK1 激酶调控的核功能
IF 3.7 3区 生物学
Nucleus Pub Date : 2024-05-16 DOI: 10.1080/19491034.2024.2353249
Pedro A. Lazo
{"title":"Nuclear functions regulated by the VRK1 kinase.","authors":"Pedro A. Lazo","doi":"10.1080/19491034.2024.2353249","DOIUrl":"https://doi.org/10.1080/19491034.2024.2353249","url":null,"abstract":"In the nucleus, the VRK1 Ser-Thr kinase is distributed in nucleoplasm and chromatin, where it has different roles. VRK1 expression increases in response to mitogenic signals. VRK1 regulates cyclin D1 expression at G0 exit and facilitates chromosome condensation at the end of G2 and G2/M progression to mitosis. These effects are mediated by the phosphorylation of histone H3 at Thr3 by VRK1, and later in mitosis by haspin. VRK1 regulates the apigenetic patterns of histones in processes requiring chromating remodeling, such as transcription, replication and DNA repair. VRK1 is overexpressed in tumors, facilitating tumor progression and resistance to genotoxic treatments. VRK1 also regulates the organization of Cajal bodies assembled on coilin, which are necessary for the assembly of different types of RNP complexes. VRK1 pathogenic variants cuase defects in Cajal bodies, functionally altering neurons with long axons and leading to neurological diseases, such as amyotrophic laterla sclerosis, spinal muscular atrophy, distal hereditay motor neuropathies and Charcot-Marie-Tooth.","PeriodicalId":19392,"journal":{"name":"Nucleus","volume":null,"pages":null},"PeriodicalIF":3.7,"publicationDate":"2024-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140969267","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Peningkatan Kesehatan dan Keselamatan Kerja dalam Bidang Dermatologi, Venereologi, dan Estetika: Tinjauan Literatur Komprehensif untuk Pendidikan Kedokteran di Indonesia 改善皮肤科、性病科和美容科的职业健康与安全：印度尼西亚医学教育综合文献综述
IF 3.7 3区 生物学
Nucleus Pub Date : 2024-05-15 DOI: 10.37010/nuc.v5i1.1536
Reza Yuridian Purwoko, Rimah Melati, Sri Idaiani, Inneke Winda Ferianasari, Evy Aryanti
{"title":"Peningkatan Kesehatan dan Keselamatan Kerja dalam Bidang Dermatologi, Venereologi, dan Estetika: Tinjauan Literatur Komprehensif untuk Pendidikan Kedokteran di Indonesia","authors":"Reza Yuridian Purwoko, Rimah Melati, Sri Idaiani, Inneke Winda Ferianasari, Evy Aryanti","doi":"10.37010/nuc.v5i1.1536","DOIUrl":"https://doi.org/10.37010/nuc.v5i1.1536","url":null,"abstract":"Peningkatan keselamatan dan kesehatan kerja (K3) di bidang dermatologi, venereologi, dan estetika sangat penting untuk melindungi penyedia layanan kesehatan dan pasien di Indonesia. Tinjauan literatur komprehensif ini bertujuan untuk menilai keadaan praktik K3 saat ini dalam spesialisasi ini dan mengidentifikasi strategi efektif untuk perbaikan. Tinjauan ini menekankan pentingnya penerapan protokol kontrol infeksi yang komprehensif, termasuk sterilisasi peralatan yang tepat, kebersihan tangan yang teliti, dan penggunaan peralatan perlindungan diri untuk mengurangi penularan penyakit infeksi. Selain itu, praktik kerja ergonomis dan pelatihan keselamatan secara teratur ditekankan untuk mengurangi cedera muskuloskeletal dan bahaya kerja lainnya. Metodologi penelitian menggunakan pendekatan kualitatif, dengan menggabungkan teknik Analisis Dokumen dan Tinjauan Sistematis. Artikel relevan diperoleh dari basis data seperti PubMed, Scopus, dan ScienceDirect, dengan fokus pada yang diterbitkan dalam bahasa Inggris dan telah ditinjau oleh peer dari tahun 2010 ke atas. Temuan menunjukkan bahwa kepatuhan ketat terhadap protokol keselamatan secara signifikan meningkatkan keselamatan di tempat kerja. Namun, terdapat kesenjangan dalam penerapan praktik ini secara konsisten di berbagai setting. Inisiatif pemerintah Indonesia telah mendukung peningkatan K3 melalui berbagai program dan regulasi, namun masih ada tantangan dalam implementasi yang efektif. Tinjauan ini juga menyoroti kebutuhan untuk pendidikan profesional berkelanjutan dan penegakan standar keselamatan yang lebih ketat untuk membina lingkungan kerja yang lebih aman. Integrasi praktik K3 ini ke dalam kurikulum pendidikan medis sangat penting untuk membekali calon profesional kesehatan dengan keterampilan dan pengetahuan yang diperlukan untuk mempertahankan standar keselamatan yang tinggi.","PeriodicalId":19392,"journal":{"name":"Nucleus","volume":null,"pages":null},"PeriodicalIF":3.7,"publicationDate":"2024-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140973233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Implementasi Model Pembelajaran Berbasis Konstruktivisme untuk Meningkatkan Kemampuan Komunikasi Matematik dan Kemandirian Siswa 实施基于建构主义的学习模式，提高学生的数学交流能力和独立性
IF 3.7 3区 生物学
Nucleus Pub Date : 2024-05-15 DOI: 10.37010/nuc.v5i1.1509
Diana Astria Gultom
{"title":"Implementasi Model Pembelajaran Berbasis Konstruktivisme untuk Meningkatkan Kemampuan Komunikasi Matematik dan Kemandirian Siswa","authors":"Diana Astria Gultom","doi":"10.37010/nuc.v5i1.1509","DOIUrl":"https://doi.org/10.37010/nuc.v5i1.1509","url":null,"abstract":"Rendahnya kemampuan komunikasi matematik dan kemandirian belajar siswa disebabkan oleh pembelajaran yang berlangsung belum mengkonstruk pemikiran siswa. Adapun upaya yang dilakukan adalah menerapkan model pembelajaran CTL berbasis konstruktivisme  yang bertujuan untuk: (1) meningkatkan kemampuan komunikasi matematik siswa (2) meningkatkan kemandirian belajar siswa (3) mengetahui aktivitas aktif siswa (4) mengetahui kemampuan guru dalam mengelola pembelajaran (5) menganalisis proses jawaban siswa dalam menyelesaikan tes kemampuan komunikasi matematik siswa. Jenis penelitian ini merupakan Penelitian Tindakan Kelas (PTK) yang dilaksanakan di SMK Immanuel Medan. Subjek Penelitian kelas X Teknik Sepeda Motor (TSM) Tahun Pelajaran 2014/2015 sebanyak 32 orang. Objek pada penelitian ini adalah pembelajaran yang menerapkan model CTL untuk mengetahui meningkatnya aktivitas aktif, kemampuan komunikasi matematik dan kemandirian  siswa. Penelitian ini terdiri dari dua siklus yaitu siklus I dan siklus II terdiri dari 8 pertemuan. Adapun hasil penelitian ini dapat dilihat dari (1) meningkatnya kemampuan komunikasi matematik siswa. Hal ini dapat dilihat pada hasil perolehan pada siklus I terdapat 25 siswa atau 78,1%  memiliki nilai minimal 2,67 dan pada siklus II meningkat menjadi 31 siswa atau 97%  dan (2) meningkatnya  kemandirian siswa. Hal ini dapat dilihat pada hasil perolehan pada siklus I terdapat 33,13%  memiliki nilai terendah dan pada siklus II meningkat  sebesar  89,84%  (3) Aktifitas aktif siswa pada siklus I terdapat 5 kriteria pengamatan yang memiliki nilai rata – rata 3,42, pada siklus II terdapat 5 kriteria pengamatan yang memiliki nilai rata – rata 4,81. (4) Proses penyelesaian jawaban siswa menyelesaikan tes kemampuan komunikasi matematik dan kemandirian siswa lebih baik.","PeriodicalId":19392,"journal":{"name":"Nucleus","volume":null,"pages":null},"PeriodicalIF":3.7,"publicationDate":"2024-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140972671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Analisis Seismisitas Sumatera Barat menggunakan Space-Time-Depth-Magnitude 利用时空-深度-震级分析西苏门答腊岛的地震活动性
IF 3.7 3区 生物学
Nucleus Pub Date : 2024-05-15 DOI: 10.37010/nuc.v5i1.1501
A. Mulyono, Mufliha Dzahabiyyah, Ika Apriliani Putri, W. Anggraeni
{"title":"Analisis Seismisitas Sumatera Barat menggunakan Space-Time-Depth-Magnitude","authors":"A. Mulyono, Mufliha Dzahabiyyah, Ika Apriliani Putri, W. Anggraeni","doi":"10.37010/nuc.v5i1.1501","DOIUrl":"https://doi.org/10.37010/nuc.v5i1.1501","url":null,"abstract":"Sumatera Barat merupakan wilayah rawan gempa karena terletak pada lempeng tektonik India-Australia  dengan lempeng Eurasia, Mentawai Fault System (MFS) dan Sumatera Fault System (SFS) atau sesar Sumatera.  Oleh karena itu, perlu adanya kajian seismik untuk menggambarkan karakteristik kegempaan. Tujuan penelitian ini adalah memperoleh karakteristik gempa Sumatera Barat melalui Space-Time-Depth-Magnitude. Alur penelitian terdiri atas 7 tahap yaitu, penambangan data, preprocessing data, perhitungan nilai b pada persamaan Gutenberg Ritcher, fraktal, jarak haversine, STDM, interpretasi hasil. Data yang dipergunakan adalah data kejadian gempa periode 2009 hingga 2023 bersumber dari Badan Meterologi, Geofisika, dan Klimatologi (BMKG) dengan membaginya menjadi 3 periode yaitu periode 1 pada 30 September 2009 hingga 24 Oktober 2010, periode 2 pada 25 Oktober 2010 hingga 10 April 2012, periode 3 pada 11 April 2012 hingga 24 April 2023. Hasil yang diperoleh adalah penurunan jarak STDM pada suatu periode mengisyaratkan gempa merusak yang akan terjadi memiliki kekuatan lebih kecil dari gempa sebelumnya, sedangkan peningkatan STDM mengisyaratkan gempa merusak yang akan terjadi memiliki kekuatan lebih besar dari gempa merusak sebelumnya. Hasil penelitian diharapkan dapat berkontribusi dalam menggambarkan keadaan seismik Sumatera Barat sehingga dapat mengantisipasi terjadinya korban jiwa.","PeriodicalId":19392,"journal":{"name":"Nucleus","volume":null,"pages":null},"PeriodicalIF":3.7,"publicationDate":"2024-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140975019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nuclear bodies: a gene expression collection for our time 核体：我们时代的基因表达集
IF 3.7 3区 生物学
Nucleus Pub Date : 2024-04-14 DOI: 10.1080/19491034.2024.2339580
Thoru Pederson
{"title":"Nuclear bodies: a gene expression collection for our time","authors":"Thoru Pederson","doi":"10.1080/19491034.2024.2339580","DOIUrl":"https://doi.org/10.1080/19491034.2024.2339580","url":null,"abstract":"Published in Nucleus (Vol. 15, No. 1, 2024)","PeriodicalId":19392,"journal":{"name":"Nucleus","volume":null,"pages":null},"PeriodicalIF":3.7,"publicationDate":"2024-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140603409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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