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精子发生过程中基因组完整性面临的挑战

IF 2.7 3区 生物学 Q3 CELL BIOLOGY
Nucleus Pub Date : 2024-04-09 DOI:10.1080/19491034.2024.2339220
Maiko Kitaoka, Yukiko M. Yamashita
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引用次数: 0

摘要

物种的延续有赖于配子的产生，只有配子产生的细胞类型才能跨代传递遗传信息。精子发生包括减数分裂后的单倍体阶段...
本文章由计算机程序翻译，如有差异，请以英文原文为准。
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Running the gauntlet: challenges to genome integrity in spermiogenesis
Species’ continuity depends on gametogenesis to produce the only cell types that can transmit genetic information across generations. Spermiogenesis, which encompasses post-meiotic, haploid stages ...
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来源期刊
Nucleus
Nucleus CELL BIOLOGY-
CiteScore
5.60
自引率
5.40%
发文量
16
审稿时长
13 weeks
期刊介绍： Nucleus is a fully open access peer-reviewed journal. All articles will (if accepted) be available for anyone to read anywhere, at any time immediately on publication. Aims & Scope: The eukaryotic cell nucleus is more than a storage organelle for genomic DNA. It is involved in critical steps of cell signaling and gene regulation, as well as the maintenance of genome stability, including DNA replication and DNA damage repair. These activities heavily depend on the spatial and temporal “functional” organization of the nucleus and its integration into the complex meshwork of cellular scaffolding. Nucleus provides a platform for presenting and discussing cutting-edge research on all aspects of biology of the cell nucleus. It brings together a multidisciplinary community of scientists working in the areas of: • Nuclear structure and dynamics • Subnuclear organelles • Chromatin organization • Nuclear transport • DNA replication and DNA damage repair • Gene expression and RNA processing • Nucleus in signaling and development Nucleus offers a variety of paper formats including: • Original Research articles • Short Reports • Reviews • Commentaries • Extra Views • Methods manuscripts.
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