Histone locus bodies: a paradigm for how nuclear biomolecular condensates control cell cycle regulated gene expression

IF 2.7 3区生物学 Q3 CELL BIOLOGY

Nucleus Pub Date : 2023-12-14 DOI:10.1080/19491034.2023.2293604

Mark S. Geisler, James P. Kemp Jr., Robert J. Duronio

引用次数: 0

Abstract

Histone locus bodies (HLBs) are biomolecular condensates that assemble at replication-dependent (RD) histone genes in animal cells. These genes produce unique mRNAs that are not polyadenylated and ...

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组蛋白基因座体：核生物分子凝聚体控制细胞周期调控基因表达的范例

组蛋白位点体(hlb)是在动物细胞中复制依赖(RD)组蛋白基因上聚集的生物分子凝聚体。这些基因产生独特的mrna，不会被聚腺苷化，而且……

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来源期刊

Nucleus CELL BIOLOGY-

CiteScore

5.60

自引率

5.40%

发文量

审稿时长

13 weeks

期刊介绍： Nucleus is a fully open access peer-reviewed journal. All articles will (if accepted) be available for anyone to read anywhere, at any time immediately on publication. Aims & Scope: The eukaryotic cell nucleus is more than a storage organelle for genomic DNA. It is involved in critical steps of cell signaling and gene regulation, as well as the maintenance of genome stability, including DNA replication and DNA damage repair. These activities heavily depend on the spatial and temporal “functional” organization of the nucleus and its integration into the complex meshwork of cellular scaffolding. Nucleus provides a platform for presenting and discussing cutting-edge research on all aspects of biology of the cell nucleus. It brings together a multidisciplinary community of scientists working in the areas of: • Nuclear structure and dynamics • Subnuclear organelles • Chromatin organization • Nuclear transport • DNA replication and DNA damage repair • Gene expression and RNA processing • Nucleus in signaling and development Nucleus offers a variety of paper formats including: • Original Research articles • Short Reports • Reviews • Commentaries • Extra Views • Methods manuscripts.