NucleusPub Date : 2024-04-11DOI: 10.1080/19491034.2024.2310452
Erin R. Butterfield, Samson O. Obado, Simon R. Scutts, Wenzhu Zhang, Brian T. Chait, Michael P. Rout, Mark C. Field
{"title":"A lineage-specific protein network at the trypanosome nuclear envelope","authors":"Erin R. Butterfield, Samson O. Obado, Simon R. Scutts, Wenzhu Zhang, Brian T. Chait, Michael P. Rout, Mark C. Field","doi":"10.1080/19491034.2024.2310452","DOIUrl":"https://doi.org/10.1080/19491034.2024.2310452","url":null,"abstract":"The nuclear envelope (NE) separates translation and transcription and is the location of multiple functions, including chromatin organization and nucleocytoplasmic transport. The molecular basis fo...","PeriodicalId":19392,"journal":{"name":"Nucleus","volume":null,"pages":null},"PeriodicalIF":3.7,"publicationDate":"2024-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140589161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
NucleusPub Date : 2024-04-10DOI: 10.1080/19491034.2024.2339214
Isabella E. Perales, Samuel D. Jones, Katherine M. Piaszynski, Pamela K. Geyer
{"title":"Developmental changes in nuclear lamina components during germ cell differentiation","authors":"Isabella E. Perales, Samuel D. Jones, Katherine M. Piaszynski, Pamela K. Geyer","doi":"10.1080/19491034.2024.2339214","DOIUrl":"https://doi.org/10.1080/19491034.2024.2339214","url":null,"abstract":"The nuclear lamina (NL) changes composition for regulation of nuclear events. We investigated changes that occur in Drosophila oogenesis, revealing switches in NL composition during germ cell diffe...","PeriodicalId":19392,"journal":{"name":"Nucleus","volume":null,"pages":null},"PeriodicalIF":3.7,"publicationDate":"2024-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140602752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
NucleusPub Date : 2024-04-09DOI: 10.1080/19491034.2024.2339220
Maiko Kitaoka, Yukiko M. Yamashita
{"title":"Running the gauntlet: challenges to genome integrity in spermiogenesis","authors":"Maiko Kitaoka, Yukiko M. Yamashita","doi":"10.1080/19491034.2024.2339220","DOIUrl":"https://doi.org/10.1080/19491034.2024.2339220","url":null,"abstract":"Species’ continuity depends on gametogenesis to produce the only cell types that can transmit genetic information across generations. Spermiogenesis, which encompasses post-meiotic, haploid stages ...","PeriodicalId":19392,"journal":{"name":"Nucleus","volume":null,"pages":null},"PeriodicalIF":3.7,"publicationDate":"2024-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140589581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
NucleusPub Date : 2024-02-21DOI: 10.1080/19491034.2024.2320656
Maria Kristha Fernandez, Molika Sinha, Mia Zidan, Malte Renz
{"title":"Nuclear actin filaments – a historical perspective","authors":"Maria Kristha Fernandez, Molika Sinha, Mia Zidan, Malte Renz","doi":"10.1080/19491034.2024.2320656","DOIUrl":"https://doi.org/10.1080/19491034.2024.2320656","url":null,"abstract":"The view on nuclear filaments formed by non-skeletal β-actin has significantly changed over the decades. Initially, filamentous actin was observed in amphibian oocyte nuclei and only under specific...","PeriodicalId":19392,"journal":{"name":"Nucleus","volume":null,"pages":null},"PeriodicalIF":3.7,"publicationDate":"2024-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139922420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
NucleusPub Date : 2024-02-08DOI: 10.37010/nuc.v4i2.1480
W. Anggraeni
{"title":"Analisis Pengelompokan Gempa Bumi di Indonesia Berdasarkan Ruang-Waktu-Kekuatan Kedalaman","authors":"W. Anggraeni","doi":"10.37010/nuc.v4i2.1480","DOIUrl":"https://doi.org/10.37010/nuc.v4i2.1480","url":null,"abstract":"\u0000 \u0000 \u0000 \u0000Indonesia merupakan daerah rawan gempa bumi dikarenakan terletak antar pertemuan lempeng Indo-Australia, Eurasia dan Pasifik. Pada periode 2009 s. 2021, terjadi 73,674 dengan kekuatan gempa berada dalam interval 1 sampai dengan 7.9 Skala Richter (SR) dan gempa lebih dari 6 SR sebanyak 162 kejadian. Analisa Seismik dalam penelitian ini mengelompokkan jarak Space, Time, Depth dan Magnitude (STDM) pada kejadian gempa ke-i dan ke-j dimana menggunakan kombinasi Metode K-Means dan Indeks Silhouette. Hasil pengelompokkan menunjukkan bahwa karakteristik seismisitas berdasarkan transformasi logaritma jarak STDM, zona 1, zona 2, zona 4, zona 5 memiliki 2 tipe, zona 7 memiliki 4 tipe sedangkan zona 3 dan zona 6 memiliki 6 tipe. Hasil penelitian ini diharapkan dapat menjadi salah satu metode alternatif dalam pengelompokkan data kegempaan sehingga dapat menggambarkan kondisi seismik suatu wilayah. \u0000 \u0000 \u0000 \u0000","PeriodicalId":19392,"journal":{"name":"Nucleus","volume":null,"pages":null},"PeriodicalIF":3.7,"publicationDate":"2024-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139791580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
NucleusPub Date : 2024-02-08DOI: 10.37010/nuc.v4i2.1480
W. Anggraeni
{"title":"Analisis Pengelompokan Gempa Bumi di Indonesia Berdasarkan Ruang-Waktu-Kekuatan Kedalaman","authors":"W. Anggraeni","doi":"10.37010/nuc.v4i2.1480","DOIUrl":"https://doi.org/10.37010/nuc.v4i2.1480","url":null,"abstract":"\u0000 \u0000 \u0000 \u0000Indonesia merupakan daerah rawan gempa bumi dikarenakan terletak antar pertemuan lempeng Indo-Australia, Eurasia dan Pasifik. Pada periode 2009 s. 2021, terjadi 73,674 dengan kekuatan gempa berada dalam interval 1 sampai dengan 7.9 Skala Richter (SR) dan gempa lebih dari 6 SR sebanyak 162 kejadian. Analisa Seismik dalam penelitian ini mengelompokkan jarak Space, Time, Depth dan Magnitude (STDM) pada kejadian gempa ke-i dan ke-j dimana menggunakan kombinasi Metode K-Means dan Indeks Silhouette. Hasil pengelompokkan menunjukkan bahwa karakteristik seismisitas berdasarkan transformasi logaritma jarak STDM, zona 1, zona 2, zona 4, zona 5 memiliki 2 tipe, zona 7 memiliki 4 tipe sedangkan zona 3 dan zona 6 memiliki 6 tipe. Hasil penelitian ini diharapkan dapat menjadi salah satu metode alternatif dalam pengelompokkan data kegempaan sehingga dapat menggambarkan kondisi seismik suatu wilayah. \u0000 \u0000 \u0000 \u0000","PeriodicalId":19392,"journal":{"name":"Nucleus","volume":null,"pages":null},"PeriodicalIF":3.7,"publicationDate":"2024-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139851347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
NucleusPub Date : 2024-02-01DOI: 10.37010/nuc.v4i2.1448
Sugiyatno Sugiyatno, P. Sidiq, Ibrahim Fikma Edrisy
{"title":"Pengaruh Teknologi 5G pada Evolusi Komunikasi: Sebuah Kajian Terhadap Perkembangan dan Implikasinya di Bidang Sains","authors":"Sugiyatno Sugiyatno, P. Sidiq, Ibrahim Fikma Edrisy","doi":"10.37010/nuc.v4i2.1448","DOIUrl":"https://doi.org/10.37010/nuc.v4i2.1448","url":null,"abstract":"Teknologi 5G merepresentasikan titik balik dalam evolusi komunikasi dan sains, menjanjikan kecepatan, kapasitas, dan latensi yang sangat ditingkatkan dibandingkan dengan generasi sebelumnya. Kajian ini mengeksplorasi potensi transformasional dari 5G dalam berbagai sektor, khususnya dalam mendukung inovasi ilmiah melalui Internet of Things (IoT), kecerdasan buatan (AI), dan analisis big data. Dengan kemampuan untuk mempercepat eksperimen dan simulasi dalam berbagai bidang sains, serta memfasilitasi kolaborasi ilmiah jarak jauh, 5G diharapkan dapat mempercepat inovasi dan penemuan ilmiah. Namun, kajian ini juga mengidentifikasi tantangan yang dihadapi dalam implementasi dan adopsi 5G, termasuk isu keamanan data, kebutuhan akan investasi infrastruktur yang besar, dan potensi masalah kesehatan serta lingkungan. Kajian ini menyarankan pendekatan interdisipliner dalam penelitian untuk mengatasi tantangan ini dan memanfaatkan teknologi 5G secara maksimal. Selain itu, penekanan pada pengurangan penggunaan energi dan adopsi sumber energi terbarukan menunjukkan kebutuhan akan komunikasi yang lebih ramah lingkungan. Kesimpulannya, 5G memiliki potensi untuk merevolusi bidang sains dan teknologi, namun keberhasilannya tergantung pada kolaborasi antarsektoral dan pengembangan strategi yang komprehensif untuk mengatasi tantangan yang ada.","PeriodicalId":19392,"journal":{"name":"Nucleus","volume":null,"pages":null},"PeriodicalIF":3.7,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139819106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
NucleusPub Date : 2024-02-01DOI: 10.37010/nuc.v4i2.1448
Sugiyatno Sugiyatno, P. Sidiq, Ibrahim Fikma Edrisy
{"title":"Pengaruh Teknologi 5G pada Evolusi Komunikasi: Sebuah Kajian Terhadap Perkembangan dan Implikasinya di Bidang Sains","authors":"Sugiyatno Sugiyatno, P. Sidiq, Ibrahim Fikma Edrisy","doi":"10.37010/nuc.v4i2.1448","DOIUrl":"https://doi.org/10.37010/nuc.v4i2.1448","url":null,"abstract":"Teknologi 5G merepresentasikan titik balik dalam evolusi komunikasi dan sains, menjanjikan kecepatan, kapasitas, dan latensi yang sangat ditingkatkan dibandingkan dengan generasi sebelumnya. Kajian ini mengeksplorasi potensi transformasional dari 5G dalam berbagai sektor, khususnya dalam mendukung inovasi ilmiah melalui Internet of Things (IoT), kecerdasan buatan (AI), dan analisis big data. Dengan kemampuan untuk mempercepat eksperimen dan simulasi dalam berbagai bidang sains, serta memfasilitasi kolaborasi ilmiah jarak jauh, 5G diharapkan dapat mempercepat inovasi dan penemuan ilmiah. Namun, kajian ini juga mengidentifikasi tantangan yang dihadapi dalam implementasi dan adopsi 5G, termasuk isu keamanan data, kebutuhan akan investasi infrastruktur yang besar, dan potensi masalah kesehatan serta lingkungan. Kajian ini menyarankan pendekatan interdisipliner dalam penelitian untuk mengatasi tantangan ini dan memanfaatkan teknologi 5G secara maksimal. Selain itu, penekanan pada pengurangan penggunaan energi dan adopsi sumber energi terbarukan menunjukkan kebutuhan akan komunikasi yang lebih ramah lingkungan. Kesimpulannya, 5G memiliki potensi untuk merevolusi bidang sains dan teknologi, namun keberhasilannya tergantung pada kolaborasi antarsektoral dan pengembangan strategi yang komprehensif untuk mengatasi tantangan yang ada.","PeriodicalId":19392,"journal":{"name":"Nucleus","volume":null,"pages":null},"PeriodicalIF":3.7,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139878841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
NucleusPub Date : 2024-02-01DOI: 10.1080/19491034.2024.2307665
Martin Rey-Millet, Kerstin Bystricky, the International Nucleome Consortium
{"title":"The genome in space and time comes of age","authors":"Martin Rey-Millet, Kerstin Bystricky, the International Nucleome Consortium","doi":"10.1080/19491034.2024.2307665","DOIUrl":"https://doi.org/10.1080/19491034.2024.2307665","url":null,"abstract":"DNA sequencing is not enough to grasp the complexity of genome organization and function. The four-dimensional (three in space, one in time) configuration of the eukaryotic nucleus varies with cell...","PeriodicalId":19392,"journal":{"name":"Nucleus","volume":null,"pages":null},"PeriodicalIF":3.7,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139668942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Gambaran Tingkat Kecemasan pada Ibu Postpartum Spontan di Puskesmas Ibrahim Adjie Kota Bandung","authors":"Nuur Afifah Ishmah, Qorinah Estiningtyas, Neneng Martini, Yogi Pramatirta, Lani Gumilang","doi":"10.37010/nuc.v4i2.1453","DOIUrl":"https://doi.org/10.37010/nuc.v4i2.1453","url":null,"abstract":"Masa postpartum merupakan masa kritis dan merupakan predisposisi terjadinya kecemasan, di mana wanita mengalami perubahan peran sebagai seorang ibu. Jika, kecemasan tidak ditangani dapat menyebabkan depresi postpartum dan dapat berpengaruh pada hasil kognitif, perilaku, dan neurofisiologis yang merugikan pada anak. Tujuan penelitian ini yaitu untuk mengetahui gambaran tingkat kecemasan pada ibu postpartum spontan di Puskesmas Ibrahim Adji Kota Bandung. Penelitian ini menggunakan metode deskriptif dengan desain penelitian cross sectional dengan sampel 36 ibu postpartum spontan. Instrumen yang digunakan yaitu instrumen Postpartum Specific Anxiety Scale (PSAS). Hasil penelitian menunjukkan sebagian besar ibu postpartum mengalami kecemasan ringan sebanyak 41.6%, kecemasan sedang sebanyak 25%, kecemasan berat sebanyak 16.7%, serta ibu postpartum yang tidak ada kecemasan sebanyak 16.7%. Simpulan penelitian ini menunjukkan ibu postpartum cenderung mengalami kecemasan ringan. Diharapkan tenaga kesehatan khususnya bidan dapat memberikan konseling serta memberikan dukungan psikologis karena hal ini sangat penting dalam masa postpartum.","PeriodicalId":19392,"journal":{"name":"Nucleus","volume":null,"pages":null},"PeriodicalIF":3.7,"publicationDate":"2024-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140485916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}