Odontology最新文献_第5页

Three-dimensional finite element analysis of the biomechanical properties of different material implants for replacing missing teeth. 对用于替代缺失牙齿的不同材料植入体的生物力学特性进行三维有限元分析。

IF 1.9 3区医学

Odontology Pub Date : 2025-01-01 Epub Date: 2024-05-08 DOI: 10.1007/s10266-024-00942-0

Yichen Gao, Xianyi He, Wei Xu, Yuyao Deng, Zhaoxin Xia, Junliang Chen, Yun He

{"title":"Three-dimensional finite element analysis of the biomechanical properties of different material implants for replacing missing teeth.","authors":"Yichen Gao, Xianyi He, Wei Xu, Yuyao Deng, Zhaoxin Xia, Junliang Chen, Yun He","doi":"10.1007/s10266-024-00942-0","DOIUrl":"10.1007/s10266-024-00942-0","url":null,"abstract":"The purpose of this study was to analyze the biomechanical properties of implants made of different materials to replace missing teeth by using three-dimensional finite element analysis and provide a theoretic basis for clinical application. CBCT data was imported into the Mimics and 3-Matic to construct the three-dimensional finite element model of a missing tooth restored by an implant. Then, the model was imported into the Marc Mentat. Based on the variations of the implant materials (titanium, titanium-zirconia, zirconia and poly (ether-ether-ketone) (PEEK)) and bone densities (high and low), a total of eight models were created. An axial load of 150 N was applied to the crown of the implant to simulate the actual occlusal situation. Both the maximum values of stresses in the cortical bone and implant were observed in the Zr-low model. The maximum displacements of the implants were also within the normal range except for the PEEK models. The cancellous bone strains were mainly distributed in the apical area of the implant, and the maximum value (3225 μstrain) was found in PEEK-low model. Under the premise of the same implant material, the relevant data from various indices in low-density bone models were larger than that in high-density bone models. From the biomechanical point of view, zirconia, titanium and titanium-zirconia were all acceptable implant materials for replacing missing teeth and possessed excellent mechanical properties, while the application of PEEK material needs to be further optimized and modified.","PeriodicalId":19390,"journal":{"name":"Odontology","volume":" ","pages":"80-88"},"PeriodicalIF":1.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140876858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The existence of cells exhibiting characteristics of both Type II and Type III cells in rat taste buds. An immunohistochemical and electron-microscopic study. 大鼠味蕾中同时存在具有 II 型和 III 型细胞特征的细胞。免疫组织化学和电子显微镜研究。

IF 1.9 3区医学

Odontology Pub Date : 2025-01-01 Epub Date: 2024-05-26 DOI: 10.1007/s10266-024-00948-8

Shuhei Inoko, Hiroki Katagiri, Maiko Tsujimura, Sumio Yoshie

{"title":"The existence of cells exhibiting characteristics of both Type II and Type III cells in rat taste buds. An immunohistochemical and electron-microscopic study.","authors":"Shuhei Inoko, Hiroki Katagiri, Maiko Tsujimura, Sumio Yoshie","doi":"10.1007/s10266-024-00948-8","DOIUrl":"10.1007/s10266-024-00948-8","url":null,"abstract":"Taste bud cells are classified into four types by their ultrastructural features. Immunohistochemical detection of taste-signaling molecules is used to distinguish cell types of taste bud cells; however, the characteristics of taste cell types such as the immunoreactivity for taste-signaling molecules have long remained unclear. We investigated the detailed characteristics of taste cells in rat vallate taste buds by electron microscopy and immunohistochemistry for gustducin, neural cell adhesion molecule (NCAM) and vesicle-associated membrane protein 2 (VAMP2), which are known as markers of Type II cells, Type III cells and both cell types, respectively. Triple immunostaining for these molecules discriminated seven kinds of cell, including the totally immunopositive cell. Electron microscopy revealed Type III cells with a typical synaptic structure and subsurface cisterna as a specialized contact between a nerve and a Type II cell. The present study clarified the existence of cells with features of both Type II and Type III cells as a subtype of taste bud cells in the rat taste bud.","PeriodicalId":19390,"journal":{"name":"Odontology","volume":" ","pages":"126-134"},"PeriodicalIF":1.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141155066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparative evaluation of six commercial adult toothpaste formulations reveals cytotoxicity and altered functions in a human oral melanocyte model: an in vitro study. 六种商用成人牙膏配方的比较评估揭示了人类口腔黑色素细胞模型的细胞毒性和功能改变：一项体外研究。

IF 1.9 3区医学

Odontology Pub Date : 2025-01-01 Epub Date: 2024-06-01 DOI: 10.1007/s10266-024-00957-7

Shilpi Goenka

{"title":"Comparative evaluation of six commercial adult toothpaste formulations reveals cytotoxicity and altered functions in a human oral melanocyte model: an in vitro study.","authors":"Shilpi Goenka","doi":"10.1007/s10266-024-00957-7","DOIUrl":"10.1007/s10266-024-00957-7","url":null,"abstract":"This study aims to compare six commercial adult toothpaste (labeled as A, B, C, D, E, and F) for cytotoxicity and melanocyte function alterations in vitro using primary human epidermal melanocytes from a Caucasian donor (HEMn-LP cells) as a model of oral melanocytes. Cells were incubated with toothpaste extracts (50% w/v) in culture media at dilutions (1:25, 1:50, 1:100, 1:200, 1:500, 1:800, and 1:1000) for 24 h. MTS and LDH assays were used to assess cytotoxicity. The effects of noncytotoxic toothpaste concentrations on melanocyte functional endpoints were then examined using spectrophotometric methods. All toothpaste showed concentration-dependent cytotoxicity that was heterogeneous across toothpaste containing SLS detergent. IC50 values of cytotoxicity followed the order: A = E > C > B > D > F. To compare toothpaste, they were tested at 1:800 and 1:1000 dilutions that were noncytotoxic after 24 h. None of the toothpaste affected cellular melanin production. However, toothpaste A, C, and D suppressed tyrosinase activity at both dilutions, while toothpaste B suppressed tyrosinase activity only at 1:800 dilution. Toothpaste A, C, E, and F elevated ROS production at 1:800 dilution, with no change at 1:1000 dilution. Toothpaste has a heterogeneous effect on melanocytes. Toothpaste B, E, and F at 1:1000 dilution were the safest as they did not alter melanocyte functions at this dilution, although toothpaste F is the least cytotoxic of these. Future studies are necessary to expand these results in a physiological environment of oral tissue. The findings of this study provide novel insight into the biocompatibility studies of toothpaste on oral melanocytes. They can aid dental practitioners and consumers in selecting noncytotoxic toothpaste that do not contribute to ROS generation by melanocytes in the oral cavity or lead to cytotoxicity and impaired cellular function.","PeriodicalId":19390,"journal":{"name":"Odontology","volume":" ","pages":"163-179"},"PeriodicalIF":1.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141186596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Long-term clinical comparison of a resin-based composite and resin modified glass ionomer in the treatment of cervical caries lesions. 树脂基复合材料和树脂改性玻璃离聚体在治疗牙颈部龋损方面的长期临床比较。

IF 1.9 3区医学

Odontology Pub Date : 2025-01-01 Epub Date: 2024-06-05 DOI: 10.1007/s10266-024-00958-6

Uzay Koç-Vural, Leyla Kerimova-Köse, Arlin Kiremitci

{"title":"Long-term clinical comparison of a resin-based composite and resin modified glass ionomer in the treatment of cervical caries lesions.","authors":"Uzay Koç-Vural, Leyla Kerimova-Köse, Arlin Kiremitci","doi":"10.1007/s10266-024-00958-6","DOIUrl":"10.1007/s10266-024-00958-6","url":null,"abstract":"This 72-month study compared the clinical effectiveness of a resin-based composite (RBC) (Spectrum TPH3, Dentsply Sirona) with a resin-modified glass ionomer cement (RMGIC) (Riva Light Cure, SDI) in restoring cervical caries lesions (CCLs). Thirty-three patients, each with at least two CCLs, were enrolled. After caries removal, the dimensions of the cavities were recorded. In a split-mouth study design, a total of 110 restorations were randomly placed. Fifty-five restorations were placed with RBC using an etch-and-rinse adhesive system (Prime&Bond NT, Dentsply Sirona), while the remaining 55 were restored with RMGIC. The restorations were assessed at baseline, 6, 12, 18, 24, 36, 60, and 72 months according to modified USPHS criteria. Statistical analysis included Pearson Chi-square, Friedman tests, Kaplan Meier, and Logistic Regression analysis (p < 0.05). After 72 months, 47 restorations in 19 patients were evaluated (55% follow-up rate). Seventy-five percent of the RBC (n = 26) and 74% (n = 21) of the RMGIC restorations were fully retained. There were no significant differences between materials regarding retention and marginal adaptation (p > 0.05). Cavity dimensions, caries activity, and retention exhibited no correlation (p > 0.05). The increase in marginal staining in both groups over time was significant (p < 0.001). RMGIC restorations exhibited higher discoloration than RBC restorations (p = 0.014). At 72 months, three secondary caries lesions were detected in both restoration groups: two RMGIC and one RBC. There were no reports of sensitivity. After 72 months, both RBC and RMGIC restorations were clinically successful, with similar retention and marginal adaptation scores. However, it is noteworthy that RMGIC restorations tend to discoloration over time compared to RBC. The trial is registered in the database of \"Clinical Trials\". The registration number is NCT0372-2758, October 29, 2018.","PeriodicalId":19390,"journal":{"name":"Odontology","volume":" ","pages":"404-415"},"PeriodicalIF":1.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141248442","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Correction: Maximum standardized uptake value in ¹¹C-methionine positron emission tomography may predict the prognosis of patients with oral squamous cell carcinoma. 更正：11C-蛋氨酸正电子发射断层扫描的最大标准化摄取值可预测口腔鳞状细胞癌患者的预后。

IF 1.9 3区医学

Odontology Pub Date : 2025-01-01 DOI: 10.1007/s10266-024-00955-9

Takeshi Kuroshima, Yoshimasa Kitagawa, Jun Sato, Shiro Watanabe, Takuya Asaka, Takahiro Abe, Hiroyuki Harada, Kenji Hirata, Yuji Kuge

引用次数: 0

The expression of salivary EGF, VEGF, endothelin, and transferrin in waterpipe and cigarette smokers. 水烟和香烟吸烟者唾液中表皮生长因子、血管内皮生长因子、内皮素和转铁蛋白的表达。

IF 1.9 3区医学

Odontology Pub Date : 2025-01-01 Epub Date: 2024-05-06 DOI: 10.1007/s10266-024-00947-9

Mohammad S Alrashdan, Hisham Al-Shorman, Amal Bouzid, Ahmed Al-Dwairi, Melanie Alazzam, Mohammad Alqudah

{"title":"The expression of salivary EGF, VEGF, endothelin, and transferrin in waterpipe and cigarette smokers.","authors":"Mohammad S Alrashdan, Hisham Al-Shorman, Amal Bouzid, Ahmed Al-Dwairi, Melanie Alazzam, Mohammad Alqudah","doi":"10.1007/s10266-024-00947-9","DOIUrl":"10.1007/s10266-024-00947-9","url":null,"abstract":"The aim of this study was to evaluate the effects of two forms of tobacco smoking, cigarettes and water pipe smoking (WPS), on the expression of a panel of salivary proteins in healthy adults. Three groups of age and gender-matched participants were enrolled in the study: never-smokers, cigarette smokers and WPS (N = 55 per group). Expression of epidermal growth factor (EGF), vascular endothelial growth factor (VEGF), endothelin and transferrin in unstimulated whole saliva was estimated using enzyme-linked immunosorbent assays. Statistical analysis consisted of one-way ANOVA and Tukey's post hoc tests, in addition to bioinformatics analysis. VEGF expression was the least in WPS (51.1 ± 14.5 pg/ml) compared to both controls (150.1 ± 13.8 pg/ml) and cigarette smokers (93 ± 9.9 pg/ml), with a significant difference in WPS (p < 0.001) and cigarette smokers (p < 0.01) compared to controls. Furthermore, transferrin showed the weakest expression in the WPS group (1238 ± 261.4 pg/ml) compared to controls (2205.6 ± 298.6 pg/ml) (p = 0.05) and cigarette smokers (1805.4 ± 244 pg/ml). Neither EGF nor endothelin expression showed any statistical difference between the groups (p > 0.05). Gene-gene interaction network demonstrated that FLT1, TFRC, KDR, VEGFB and PGF genes had the highest potential for interaction with the studied proteins. Further functional annotations on the identified markers in the interaction network were performed to identify HIF-1 pathways among the most relevant pathways. In conclusion, smoking habits alter the expression of salivary VEGF and transferrin, which may correspond to early sub-clinical changes in the oral mucosa. The clinical relevance of these salivary changes requires further research.","PeriodicalId":19390,"journal":{"name":"Odontology","volume":" ","pages":"380-389"},"PeriodicalIF":1.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140859867","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effects of pre-heating on physical-mechanical-chemical properties of contemporary resin composites. 预热对当代树脂复合材料物理-机械-化学特性的影响

IF 1.9 3区医学

Odontology Pub Date : 2025-01-01 Epub Date: 2024-05-27 DOI: 10.1007/s10266-024-00953-x

Thamires Bueno, Nivien Masoud, Anna Akkus, Italo Silva, Karen McPherson, Adilson Yoshio Furuse, Fabio Rizzante

{"title":"Effects of pre-heating on physical-mechanical-chemical properties of contemporary resin composites.","authors":"Thamires Bueno, Nivien Masoud, Anna Akkus, Italo Silva, Karen McPherson, Adilson Yoshio Furuse, Fabio Rizzante","doi":"10.1007/s10266-024-00953-x","DOIUrl":"10.1007/s10266-024-00953-x","url":null,"abstract":"This research assessed the effects of pre-heating on the physical-mechanical-chemical properties of different resin composites. For this, resin composites were evaluated in 6 levels: Admira/ADM, Vitra/VIT, Filtek Supreme/FS, Filtek Supreme Flowable/FSF, Filtek One/FO, and Filtek Bulk Fill Flowable/FBF; temperature was evaluated in 4 levels using a composite heater: room temperature/22 ºC, 37 ºC, 54 ºC, and 68 ºC. Response variables were: degree of conversion/DC, flexural strength/FS and color stability/ΔE (immediately after light curing/LC, after 7 days of dark-dry-storage, and after 24 h and 3 days of artificial aging in water at 60 ºC). Data were subjected to 2-way ANOVA (DC and FR) and 3-way repeated measurements ANOVA (ΔE), all followed by Tukey's test (α = 5%). DC were similar (FBF, FS, and FSF) or increased (ADM, FO, and VIT) as the temperature increased. Results of FR were unchanged or increased for all composites except VIT and ADM. High-viscosity composites (VIT and FS) showed higher FR values than low-viscosity composite (FSF). For bulk-fill composites, FBF and FO showed similar results, but lower than high-viscosity composites. Results of color stability showed acceptable values up to 3 days aging except for ADM and FSF. ΔE was not influenced by pre-heating and, overall, ΔE: FS < VIT < FO < FSF < ADM < FBF. Only VIT and FS showed ΔE ≤ 3.3 (clinical threshold). Therefore, the effects of pre-heating depend on the material. The tested materials generally showed similar or enhanced properties after pre-heating (except ADM and VIT).","PeriodicalId":19390,"journal":{"name":"Odontology","volume":" ","pages":"135-142"},"PeriodicalIF":1.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141155060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Examining enamel-surface demineralization upon exposure to acidic solutions and the remineralization potential of milk and artificial saliva. 研究接触酸性溶液后珐琅质表面的脱矿化以及牛奶和人工唾液的再矿化潜力。

IF 1.9 3区医学

Odontology Pub Date : 2025-01-01 Epub Date: 2024-06-21 DOI: 10.1007/s10266-024-00960-y

Sri Larnani, Youngha Song, Soyeon Kim, Young-Seok Park

{"title":"Examining enamel-surface demineralization upon exposure to acidic solutions and the remineralization potential of milk and artificial saliva.","authors":"Sri Larnani, Youngha Song, Soyeon Kim, Young-Seok Park","doi":"10.1007/s10266-024-00960-y","DOIUrl":"10.1007/s10266-024-00960-y","url":null,"abstract":"The enamel surface may undergo demineralization due to exposure to acidic substances and the remineralization of the etched enamel is crucial to regain or maintain integrity. This study aimed to investigate the erosive effect of 10 acidic solutions on tooth enamel and the remineralization capacity of milk and artificial saliva by measuring surface roughness (Ra), enamel depth, and microhardness. A total of 80 bovine incisor enamel specimens were immersed in 10 different acidic solutions, including four different acidic drinks, three different citric acid solutions, and three different citric acid buffer solutions, for 1 h. After demineralization, the specimens were immersed in milk and artificial saliva for 3 h. Surface roughness, enamel abraded depth, and microhardness were measured before demineralization, in-between time intervals and after remineralization. Data were analyzed using Friedman and Kruskal-Wallis tests (p < 0.05). The results indicate a significant difference in surface roughness between the measurements taken at different time intervals, particularly between the baseline and after 1 h demineralization. Also, the specimens immersed in CAB1 exhibited greatest increase in Ra among other acidic solutions (Δ: 0.18 ± 0.07). Moreover, only the microhardness increased after remineralization (p < 0.05). Enamel demineralization using various acidic solutions revealed increased Ra and enamel abraded depth, and decreased microhardness. The use of remineralization agents, milk and artificial saliva, demonstrated an increase in microhardness. This study provides insights into the effects of different acidic solutions and potential remineralization agents on tooth enamel.","PeriodicalId":19390,"journal":{"name":"Odontology","volume":" ","pages":"201-212"},"PeriodicalIF":1.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141432456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hormone replacement therapy did not alleviate temporomandibular joint inflammatory pain in ovariectomized rats. 激素替代疗法不能缓解卵巢切除大鼠的颞下颌关节炎性疼痛。

IF 1.9 3区医学

Odontology Pub Date : 2025-01-01 Epub Date: 2024-07-02 DOI: 10.1007/s10266-024-00964-8

Giovana Paola Heck Kroeff, Josimar Macedo de Castro, Hemily Barbosa Braga, Tenille Dal Bosco, Thais Collioni de Oliveira, Iala Thais de Sousa Morais, Liciane Fernandes Medeiros, Wolnei Caumo, Dirson J Stein, Iraci L S Torres

{"title":"Hormone replacement therapy did not alleviate temporomandibular joint inflammatory pain in ovariectomized rats.","authors":"Giovana Paola Heck Kroeff, Josimar Macedo de Castro, Hemily Barbosa Braga, Tenille Dal Bosco, Thais Collioni de Oliveira, Iala Thais de Sousa Morais, Liciane Fernandes Medeiros, Wolnei Caumo, Dirson J Stein, Iraci L S Torres","doi":"10.1007/s10266-024-00964-8","DOIUrl":"10.1007/s10266-024-00964-8","url":null,"abstract":"This study had the aim of examining the relationships between variations in estrogen levels resulting from ovariectomy, and estrogen hormone replacement therapy (HRT) in rats subjected to an orofacial inflammatory pain model. Eighty adult female Wistar rats were initially divided into 2 groups: Sham or ovariectomy (OVX-D1). Seven days later (D7), the rats were subjected to an unilateral infiltration of Freund's Complete Adjuvant (CFA) or saline solution into the right temporomandibular joint (TMJ). Then, rats received 17β-estradiol (28 µg/kg/day) or placebo for 21 days (D10-D31). Nociception was evaluated by the von Frey (VF) and the Hot Plate (HP) tests, and depressive-like behavior by the Forced Swimming (FS) test. On D32 all rats were euthanized and serum, hippocampus and brainstem were collected. The CFA groups presented a mechanical hyperalgesia until day 21 (p ≤ 0.05). No differences were observed among groups in the HP (p = 0.735), and in the immobility and swimming time of the FS (p = 0.800; p = 0.998, respectively). In the brainstem, there was a significant difference in the TNF-ɑ levels (p = 0.043), and a marginal significant difference in BDNF levels (p = 0.054), without differences among groups in the hippocampal BDNF and TNF-ɑ levels (p = 0.232; p = 0.081, respectively). In conclusion, the hormone replacement therapy did not alleviate orofacial pain in ovariectomized rats. However, there is a decrease in brainstem TNF-ɑ levels in the animals submitted to both models, which was partially reverted by HRT.","PeriodicalId":19390,"journal":{"name":"Odontology","volume":" ","pages":"232-244"},"PeriodicalIF":1.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141492884","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Assessment of the effect of experimental gel of pregabalin associated with 35% hydrogen peroxide bleaching on bovine dental enamel: an in vitro study. 评估普瑞巴林实验凝胶与 35% 过氧化氢漂白剂对牛牙釉质的影响：一项体外研究。

IF 1.9 3区医学

Odontology Pub Date : 2025-01-01 Epub Date: 2024-07-26 DOI: 10.1007/s10266-024-00978-2

Gabriela Monteiro Barbosa Xavier, Giovana Sholheid Gil, Yngrid Fernanda Oliveira Paes, Lindalva Maria de Meneses Costa Ferreira, Cecy Martins Silva, Roseane Maria Ribeiro-Costa, Jesuína Lamartine Nogueira Araújo

{"title":"Assessment of the effect of experimental gel of pregabalin associated with 35% hydrogen peroxide bleaching on bovine dental enamel: an in vitro study.","authors":"Gabriela Monteiro Barbosa Xavier, Giovana Sholheid Gil, Yngrid Fernanda Oliveira Paes, Lindalva Maria de Meneses Costa Ferreira, Cecy Martins Silva, Roseane Maria Ribeiro-Costa, Jesuína Lamartine Nogueira Araújo","doi":"10.1007/s10266-024-00978-2","DOIUrl":"10.1007/s10266-024-00978-2","url":null,"abstract":"To assess the effect of bleaching with gel of pregabalin associated with 35% hydrogen peroxide on the mechanical and chemical properties and ultramorphology of dental enamel. Thirty-six (36) specimens of bovine dental incisors were obtained and divided into three groups (n = 12), namely: CG = bleaching with 35% hydrogen peroxide; KFG = bleaching with 5% potassium nitrate and 2% sodium fluoride gel + 35% hydrogen peroxide; and PGG = bleaching with experimental gel of pregabalin + 35% hydrogen peroxide. The specimens were assessed with respect to Knoop microhardness, surface roughness, and colour change, before and after bleaching. They were also assessed using scanning electron microscopy and energy-dispersive spectroscopy after treatments. All groups exhibited an increase in surface roughness and a reduction in Knoop microhardness after the protocols. There was colour change in all groups, with no difference between them. In addition, there were changes in enamel morphology and non-significant loss of calcium and phosphorus. The experimental gel of pregabalin did not influence the action of 35% hydrogen peroxide, yielding results similar to those of the other groups assessed in all the parameters. Therefore, the gel of pregabalin can be an alternative for topical application on the surfaces of the teeth in association with bleaching treatments.","PeriodicalId":19390,"journal":{"name":"Odontology","volume":" ","pages":"331-339"},"PeriodicalIF":1.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141766894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0